Displaying publications 21 - 40 of 80 in total

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  1. Queb-Pech NM, Núñez-Oreza LA, Estrada-Méndez A, Tamay-Segovia P, Collí-Heredia JP, Blum-Domínguez SC
    Trop Biomed, 2022 Dec 01;39(4):575-578.
    PMID: 36602218 DOI: 10.47665/tb.39.4.014
    Malaria and dengue fever are among the most common mosquito-borne diseases worldwide; however, reports of coinfection are rare. We present a case of severe malaria and dengue coinfection in a 16-yearold female patient presenting with fever, thrombocytopenia, pleural effusion, myopericarditis, and acute respiratory distress syndrome. Dengue infection was confirmed by the presence of immunoglobin M antibodies and nonstructural protein 1, while malaria was confirmed by the presence of Plasmodium vivax in thick and thin blood smears. This is the first report of a dengue/malaria coinfection in Mexico.
    Matched MeSH terms: Mexico
  2. Palm HW, Morales-Ávila JR, Galván-Magaña F, Haseli M
    Syst Parasitol, 2020 04;97(2):133-142.
    PMID: 32065375 DOI: 10.1007/s11230-020-09904-w
    Two new tentaculariid species were found infecting carcharhiniform sharks from off the coasts of Malaysian Borneo and the southwestern coast of the Baja California Sur, Mexico. Both new species exhibit a homeoacanthous heteromorphous basal and a homeoacanthous homeomorphous metabasal armature. Since this hook arrangement is unique within the tentaculariids and the taxonomy in this group deeply depends on the tentacular armature, Reimeriella n. g. is erected to accommodate R. varioacantha n. sp. ex Carcharhinus sorrah (Müller & Henle) and R. mexicoensis n. sp. ex Sphyrna lewini (Griffith & Smith). Unlike R. mexicoensis n. sp., R. varioacantha n. sp. has a pars bothrialis not overlapping the pars bulbosa and the number of testes is higher. Reimeriella mexicoensis n. sp. possesses very large uncinate to falcate hooks in the basal armature, while in R. varioacantha n. sp. these hooks are almost the same in size as the remaining hooks in both the basal and metabasal armature. The latter species is the first tentaculariid species where the metabasal armature very closely resembles an eutetrarhynchid with a heteroacanthous typical homeomorphous metabasal armature and a high number of spiniform hooks per half spiral row (10-11 vs 6-7 in R. mexicoensis n. sp.) in the metabasal and apical armature. This pattern provides further morphological evidence for the close relationship of the Eutetrarhynchoidea and the Tentacularioidea. Reimeriella varioacantha n. sp. enriches the trypanorhynch fauna from off the coast of Malaysian Borneo while R. mexicoensis n. sp. is a novel record of a tentaculariid trypanorhynch from the Mexican Pacific.
    Matched MeSH terms: Mexico
  3. Ozer J, Alon G, Leykin D, Varon J, Aharonson-Daniel L, Einav S
    BMC Med Ethics, 2019 12 26;20(1):102.
    PMID: 31878920 DOI: 10.1186/s12910-019-0439-x
    BACKGROUND: The ethical principle of justice demands that resources be distributed equally and based on evidence. Guidelines regarding forgoing of CPR are unavailable and there is large variance in the reported rates of attempted CPR in in-hospital cardiac arrest. The main objective of this work was to study whether local culture and physician preferences may affect spur-of-the-moment decisions in unexpected in-hospital cardiac arrest.

    METHODS: Cross sectional questionnaire survey conducted among a convenience sample of physicians that likely comprise code team members in their country (Indonesia, Israel and Mexico). The questionnaire included details regarding respondent demographics and training, personal value judgments and preferences as well as professional experience regarding CPR and forgoing of resuscitation.

    RESULTS: Of the 675 questionnaires distributed, 617 (91.4%) were completed and returned. Country of practice and level of knowledge about resuscitation were strongly associated with avoiding CPR performance. Mexican physicians were almost twicemore likely to forgo CPR than their Israeli and Indonesian/Malaysian counterparts [OR1.84 (95% CI 1.03, 3.26), p = 0.038]. Mexican responders also placed greater emphasison personal and patient quality of life (p 

    Matched MeSH terms: Mexico
  4. Ortiz RH, Leon DA, Estevez HO, Martin A, Herrera JL, Romo LF, et al.
    Clin Exp Immunol, 2009 Aug;157(2):271-81.
    PMID: 19604267 DOI: 10.1111/j.1365-2249.2009.03941.x
    Buruli ulcer (BU) is the third most common mycobacterial disease in immunocompetent hosts. BU is caused by Mycobacterium ulcerans, which produces skin ulcers and necrosis at the site of infection. The principal virulence factor of M. ulcerans is a polyketide-derived macrolide named mycolactone, which has cytotoxic and immunosuppressive activities. We determined the severity of inflammation, histopathology and bacillary loads in the subcutaneous footpad tissue of BALB/c mice infected with 11 different M. ulcerans isolates from diverse geographical areas. Strains from Africa (Benin, Ghana, Ivory Coast) induced the highest inflammation, necrosis and bacillary loads, whereas the strains collected from Australia, Asia (Japan, Malaysia, New Guinea), Europe (France) and America (Mexico) induced mild inflammation. Subsequently, animals were infected with the strain that exhibited the highest (Benin) or lowest (Mexico) level of virulence in order to analyse the local immune response generated. The Mexican strain, which does not produce mycolactone, induced a predominantly T helper type 1 (Th1) cytokine profile with constant high expression of the anti-microbial peptides beta defensins 3 and 4, in co-existence with low expression of the anti-inflammatory cytokines interleukin (IL)-10, IL-4 and transforming growth factor (TGF)-beta. The highly virulent strain from Benin which produces mycolactone A/B induced the opposite pattern. Thus, different local immune responses were found depending on the infecting M. ulcerans strain.
    Matched MeSH terms: Mexico
  5. Notzon F
    Pediatrics, 1984 Oct;74(4 Pt 2):648-66.
    PMID: 6384917
    Matched MeSH terms: Mexico
  6. Norain Mohd Tamsir, Norhaizan Mohd Esa, Siti Nursalwah Che Omar, Nurul Husna Shafie
    MyJurnal
    Introduction: Manilkara zapota (L.) P. Royen or sapodilla is a fruit-bearing tree that has been cultivated mainly in tropical areas including Mexico and South East Asia. The fruits and the other parts of M. zapota plant have been used since ages ago for various medicinal purposes. However, the data on the antioxidant properties of various parts of M. zapota is limited. Therefore, we aimed to measure the content and capacity of antioxidants in various M. zapota plant parts and also to screen the phytoconstituents present in the part with the highest antioxidant content and capacity. Methods: The in vitro antioxidant evaluation including the content of total phenolic (TPC) and total flavonoids (TFC) as well as β-carotene bleaching and 1-diphenyl-2-picrylhydrazyl (DPPH) scavenging ability of the leaves, seeds, flesh, and peels of M. zapota extracted by aqueous and ethanol were determined. The plant part that exhibited the highest TPC, TFC, and antioxidant capacity was selected for phytoconstituents identification using liq- uid chromatography mass spectrometry. Results: M. zapota leaves aqueous extract exhibited the highest TPC, TFC, and antioxidant capacities and therefore selected for phytoconstituents identification. Our study provide additional data in which a total of 39 phytoconstituents have been identified in the M. zapota leaves including m-coumaric acid, quinic acid, robinetinidol-4alpha-ol, isoorientin 6’’-O-caffeate, apocynin A, and C16 Sphinganine. Conclusion: Thus, our study revealed that M. zapota leaves aqueous extract has potential as a promising naturally-occurring an- tioxidant candidate which could be useful for medicinal and nutritional functions.
    Matched MeSH terms: Mexico
  7. Nazar GP, Lee JT, Arora M, Millett C
    Nicotine Tob Res, 2016 May;18(5):1230-9.
    PMID: 26610936 DOI: 10.1093/ntr/ntv261
    INTRODUCTION: In high-income countries, secondhand smoke (SHS) exposure is higher among disadvantaged groups. We examine socioeconomic inequalities in SHS exposure at home and at workplace in 15 low- and middle-income countries (LMICs).
    METHODS: Secondary analyses of cross-sectional data from 15 LMICs participating in Global Adult Tobacco Survey (participants ≥ 15 years; 2008-2011) were used. Country-specific analyses using regression-based methods were used to estimate the magnitude of socioeconomic inequalities in SHS exposure: (1) Relative Index of Inequality and (2) Slope Index of Inequality.
    RESULTS: SHS exposure at home ranged from 17.4% in Mexico to 73.1% in Vietnam; exposure at workplace ranged from 16.9% in Uruguay to 65.8% in Bangladesh. In India, Bangladesh, Thailand, Malaysia, Philippines, Vietnam, Uruguay, Poland, Turkey, Ukraine, and Egypt, SHS exposure at home reduced with increasing wealth (Relative Index of Inequality range: 1.13 [95% confidence interval [CI] 1.04-1.22] in Turkey to 3.31 [95% CI 2.91-3.77] in Thailand; Slope Index of Inequality range: 0.06 [95% CI 0.02-0.11] in Turkey to 0.43 [95% CI 0.38-0.48] in Philippines). In these 11 countries, and in China, SHS exposure at home reduced with increasing education. In India, Bangladesh, Thailand, and Philippines, SHS exposure at workplace reduced with increasing wealth. In India, Bangladesh, Thailand, Philippines, Vietnam, Poland, Russian Federation, Turkey, Ukraine, and Egypt, SHS exposure at workplace reduced with increasing education.
    CONCLUSION: SHS exposure at homes is higher among the socioeconomically disadvantaged in the majority of LMICs studied; at workplaces, exposure is higher among the less educated. Pro-equity tobacco control interventions alongside targeted efforts in these groups are recommended to reduce inequalities in SHS exposure.
    IMPLICATIONS: SHS exposure is higher among the socioeconomically disadvantaged groups in high-income countries. Comprehensive smoke-free policies are pro-equity for certain health outcomes that are strongly influenced by SHS exposure. Using nationally representative Global Adult Tobacco Survey (2008-2011) data from 15 LMICs, we studied socioeconomic inequalities in SHS exposure at homes and at workplaces. The study showed that in most LMICs, SHS exposure at homes is higher among the poor and the less educated. At workplaces, SHS exposure is higher among the less educated groups. Accelerating implementation of pro-equity tobacco control interventions and strengthening of efforts targeted at the socioeconomically disadvantaged groups are needed to reduce inequalities in SHS exposure in LMICs.
    Study name: Global Adults Tobacco Survey (GATS-2011)
    Matched MeSH terms: Mexico/epidemiology
  8. Moreno-Legorreta M, Tozar-Zamora I, Serrano-Pinto V
    Trop Biomed, 2020 Sep 01;37(3):722-729.
    PMID: 33612785 DOI: 10.47665/tb.37.3.722
    Chikungunya virus infection had not been reported by the National Secretary of Health of the State of Baja California Sur, Mexico before 2015, and until now, no information of the disease has been published. Thus, the objective of this study was to assess the tendency that the disease has shown since its introduction. The total number of cases in the state was analyzed, and the incidence rate of infection was evaluated in the general population, age groups, and gender. From 2015-2019, the year with the highest number of reported cases was 2016 with 210 cases, but no cases were reported from 2018-2019. The gender with the highest number of cases was female. The most affected age group was adults 45-64 years of age.
    Matched MeSH terms: Mexico
  9. Morales-Figueroa GG, Castro-García M, Esparza-Romero J, López-Mata MA, Quihui-Cota L
    Trop Biomed, 2019 Sep 01;36(3):718-725.
    PMID: 33597494
    Caborca is one of the most productive asparagus-growing regions in the state of Sonora in northwest Mexico, an area where some fresh fruits and vegetables are sold at unregulated open-air street markets. This is a cross-sectional study in which fifty bundles of asparagus for exportation, 50 bundles of sub-standard asparagus, and 50 bundles of asparagus from open-air markets were selected randomly and then subjected to Faust, Kinyoun and ELISA testing to detect intestinal parasites. Pearson's chi-square (χ2) and Student-NewmanKeuls tests were used to estimate differences among the sampling site groups (P < 0.05). The pathogens Cryptosporidium spp. (29%) G. intestinalis (5%) and Cyclospora spp. (3%) were found in the asparagus sold in the region. The prevalence of Cryptosporidium spp. was higher in both the sub-standard asparagus and the product sampled from the open-air markets than in the samples for exportation (P < 0.05). This is the first study to demonstrate contamination by intestinal parasites in asparagus sold in different markets in northwest Mexico.
    Matched MeSH terms: Mexico
  10. Medina MFE, Alaba PA, Estrada-Zuñiga ME, Velázquez-Ordoñez V, Barbabosa-Pliego A, Salem MZM, et al.
    Microb Pathog, 2017 Dec;113:286-294.
    PMID: 29101063 DOI: 10.1016/j.micpath.2017.10.053
    The aim of this study is to investigate the biopotency of methanolic extracts of Vitex mollis, Psidium guajava, Dalbergia retusa, and Crescential alata leaves against various staphylococcal strains isolated from cattle and rabbits. Methicillin-resistant S. aureus strains were isolated from cattle, while other strains were isolated from rabbits using standard methodology. The total phytochemical phenolic and saponins contents were obtained being the main groups of the antinutritional factors. The antimicrobial activity of the extracts against the standard culture of S. aureus (control) and S. aureus isolated from cattle and rabbits were investigated comparatively relative to that of oxacillin. It was found that both the control S. aureus and the isolated S. aureus are susceptible to all the four plant extracts, and sensitive to oxacillin. Of all the S. aureus including the control, MRSA2 is the most susceptible to all the extracts at 1000 μg/mL, except that of V. mollis where it is the least susceptible. Among all the plant extracts, P. guajava is the most active against MRSA2 and SOSA2. Therefore, the isolates from cattle (MRSA1 and MRSA2) are more susceptible to all the plant extracts than the isolates from rabbits. Among all the rabbit isolates, CoNS3 is the least susceptible to the extracts. Since all the plant extracts exhibit remarkable inhibitory activities against all the S. aureus strains, they are promising towards the production of therapeutic drugs.
    Matched MeSH terms: Mexico
  11. Marghany M
    Mar Pollut Bull, 2014 Dec 15;89(1-2):20-29.
    PMID: 25455367 DOI: 10.1016/j.marpolbul.2014.10.041
    In this work, a genetic algorithm is applied for the automatic detection of oil spills. The procedure is implemented using sequences from RADARSAT-2 SAR ScanSAR Narrow single-beam data acquired in the Gulf of Mexico. The study demonstrates that the implementation of crossover allows for the generation of an accurate oil spill pattern. This conclusion is confirmed by the receiver-operating characteristic (ROC) curve. The ROC curve indicates that the existence of oil slick footprints can be identified using the area between the ROC curve and the no-discrimination line of 90%, which is greater than that of other surrounding environmental features. In conclusion, the genetic algorithm can be used as a tool for the automatic detection of oil spills, and the ScanSAR Narrow single-beam mode serves as an excellent sensor for oil spill detection and survey.
    Matched MeSH terms: Gulf of Mexico
  12. Low EV, Lee M, Bauer C, Fisher-Hoch SP, McCormick JB, Abughosh S, et al.
    Metab Syndr Relat Disord, 2022 Oct;20(8):440-450.
    PMID: 35819796 DOI: 10.1089/met.2021.0151
    Background: This retrospective cohort study aimed to examine the interaction effect between puberty stage and weight status on individual and clustering of cardiometabolic risk factors (CMRFs) among Mexican American children and adolescents. A total of 333 children and adolescents (aged 8-18 years) enrolled in the Cameron County Hispanic Cohort (CCHC) from 2014 to 2020 were included in the study. Methods: CCHC is a longitudinal, randomly recruited cohort based on the United States Census tracts/blocks of Mexican Americans living on the Texas-Mexico border. Individual CMRFs, including high blood pressure, central obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol, and insulin resistance (IR) were assessed. Clustering of CMRFs is defined as the presence of three or more individual CMRFs. Puberty stages were assessed using the Tanner criteria. Multivariable logistic regressions were conducted to assess the association of puberty, weight status, and the interaction of the two main exposures with individual and clustering of CMRFs. Results: We observed that weight status had a dominant effect on all CMRF measures. The effect was especially prominent on central obesity and clustering of CMRFs. There were 95.4% of children with central obesity and 98.4% of those with clustering of CMRF were either overweight or obese. Entering puberty was associated with an increased risk of having IR [Tanner stage 2 vs. 1: odds ratio (OR) = 3.25, 95% confidence interval (95% CI) 1.28-8.27; Tanner stage 3 vs. 1: OR = 3.50, 95% CI 1.45-8.46] and hypertriglyceridemia (Tanner stage 2 vs. 1: OR = 2.67, 95% CI 1.11-6.45). However, the effects were not observed among those reaching the end of puberty (Tanner stage 4 and 5). Conclusions: A significant interaction effect between weight status and puberty was not detected on any individual CMRF and in the clustering of CMRFs. Other factors positively associated with individual CMRFs, especially IR, were being female and having a family history of diabetes.
    Matched MeSH terms: Mexico/epidemiology
  13. Loo JL, Keng SL, Ramírez-Espinosa IG, Nor Hadi NM, Ramírez-Gutiérrez JA, Shoesmith W
    Asia Pac Psychiatry, 2021 Mar;13(1):e12437.
    PMID: 33188568 DOI: 10.1111/appy.12437
    BACKGROUND: Borderline personality disorder (BPD) contributes to suicide-related morbidity and mortality and requires more intensive psychotherapeutic resources due to its high mental health service usage. Accessibility to an evidence-based treatment program is a cornerstone to support patients with BPD and part of broader suicide prevention efforts as well as improving their quality of life.

    AIMS: In this article, the authors aim to discuss and review available dialectical behavior therapy (DBT) and DBT-informed services of selected countries in the Asia-Pacific Rim, namely Singapore, Malaysia, and Mexico.

    MATERIALS & METHODS: We contacted providers of different services and gathered information on the process of setting up the service and adapting the treatment, in addition to reviewing the available literature published in the countries.

    RESULTS: To date, there have been a pair of DBT-informed services in Singapore, four in Malaysia, and several in Mexico with a few of them offering standard DBT. Different efforts have been put in place to increase the accessibility to training and also the number of DBT practitioners.

    DISCUSSION: Important considerations during the process of setting up new services include the use of domestic examples and local language that are contextually appropriate for the local community. Selected challenges faced in common include shortage of workforce, affordability of training programs, and the need for language adaptation with or without translation.

    CONCLUSION: Further long-term evaluation of locally adapted DBT-informed mental health services will help to elucidate the effectiveness and efficacy of the program which will potentially serve as a guide for other resource-scarce regions.

    Matched MeSH terms: Mexico
  14. Lombardo E
    Genus, 1983 Jan-Dec;39(1-4):167-73.
    PMID: 12266118
    "A tentative approximation of the expectation of life at 60-65 years, for populations with defective demographic statistics, is explored and expounded on the basis of a recent Horiuchi and [Coale] paper." The method is applied to data for El Salvador, Mexico, Puerto Rico, and Peninsular Malaysia, and it is shown that the method can be used on actual data, although it requires some drastic rounding off. (summary in ENG, FRE)
    Matched MeSH terms: Mexico
  15. Locke KD, Church AT, Mastor KA, Curtis GJ, Sadler P, McDonald K, et al.
    Pers Soc Psychol Bull, 2017 Jul;43(7):1033-1049.
    PMID: 28903706 DOI: 10.1177/0146167217704192
    We assessed self-consistency (expressing similar traits in different situations) by having undergraduates in the United States ( n = 230), Australia ( n = 220), Canada ( n = 240), Ecuador ( n = 101), Mexico ( n = 209), Venezuela ( n = 209), Japan ( n = 178), Malaysia ( n = 254), and the Philippines ( n = 241) report the traits they expressed in four different social situations. Self-consistency was positively associated with age, well-being, living in Latin America, and not living in Japan; however, each of these variables showed a unique pattern of associations with various psychologically distinct sources of raw self-consistency, including cross-situationally consistent social norms and injunctions. For example, low consistency between injunctive norms and trait expressions fully explained the low self-consistency in Japan. In accord with trait theory, after removing normative and injunctive sources of consistency, there remained robust distinctive noninjunctive self-consistency (reflecting individuating personality dispositions) in every country, including Japan. The results highlight how clarifying the determinants and implications of self-consistency requires differentiating its distinctive, injunctive, and noninjunctive components.
    Matched MeSH terms: Mexico
  16. Lee SC, Hashim R, Motamedi S, Song KI
    ScientificWorldJournal, 2014;2014:494020.
    PMID: 24955408 DOI: 10.1155/2014/494020
    Threats to beaches have accelerated the coastal destruction. In recent decades, geotextile tubes were used around the world to prevent coastal erosion, to encourage beach nourishment, and to assist mangrove rehabilitation. However, the applications of geotextile tube in sandy and muddy coasts have different concerns as the geological settings are different. Applications of geotextile tubes in sandy beaches were mainly to prevent coastline from further erosion and to nourish the beach. However, for the muddy coasts, mangrove rehabilitation and conservation were additional concerns in coastal management schemes. The mangrove forests are natural barriers which can be found on the muddy coasts of many tropical countries. In this paper, the viability of geotextile tubes in sandy and muddy beaches was analysed. The advantages and disadvantages of the utilization of geotextile tubes in coastal management were discussed based on the experiences from the tropical countries such as Mexico, Malaysia, and Thailand. From the case studies, impressive improvements in coastal restoration after installation of geotextile tubes were shown. Based on the discussion, several recommendations to improve the application of geotextile tubes were suggested in this paper.
    Matched MeSH terms: Mexico
  17. Ladner J, Madi F, Jayasundera R, Saba J, Audureau E
    J Comp Eff Res, 2023 Jul;12(7):e220210.
    PMID: 37278943 DOI: 10.57264/cer-2022-0210
    Aim: Survival of patients with Hodgkin's lymphoma is lower in in low- and middle-income countries, but factors leading to these outcomes are poorly understood. The objective of this study was to identify predictive factors associated with overall survival among cancer patients undergoing therapy in seven low- and middle-income countries. Materials & methods: A multicenter cohort was conducted in Egypt, Malaysia, Mexico, Peru, Philippines, Thailand and Ukraine. Results. A total of 460 patients were included. Phone-based support during patient follow-up and number of patients seen by the physician provided a positive impact, while the number of adverse events remains a predictor of death and physician decision to stop treatment. Conclusion: Furthers research on the potential benefit of phone-based programs to support patients with chronic diseases treatments should be explored in less developed countries.
    Matched MeSH terms: Mexico/epidemiology
  18. Kyriakos CN, Erinoso O, Driezen P, Thrasher JF, Katanoda K, Quah ACK, et al.
    BMJ Open, 2024 Apr 19;14(4):e083080.
    PMID: 38642995 DOI: 10.1136/bmjopen-2023-083080
    INTRODUCTION: The global market of flavour capsule cigarettes (FCCs) has grown significantly over the past decade; however, prevalence data exist for only a few countries. This study examined prevalence and perceptions of FCCs among adults who smoke across five countries.

    METHODS: Cross-sectional data among adults who smoked cigarettes came from the International Tobacco Control Policy Evaluation Project Surveys-Brazil (2016/2017), Japan (2021), Republic of Korea (2021), Malaysia (2020) and Mexico (2021). FCCs use was measured based on reporting one's usual/current brand or favourite variety has flavour capsule(s). Perceptions of the harmfulness of one's usual brand versus other brands were compared between those who used capsules versus no capsules. Adjusted logistic regression models examined correlates of FCC use.

    RESULTS: There were substantial differences in the prevalence of FCC use among adults who smoke across the five countries: Mexico (50.3% in 2021), Republic of Korea (31.8% in 2021), Malaysia (26.5% in 2020), Japan (21.6% in 2021) and Brazil (6.7% in 2016/2017). Correlates of FCC use varied across countries. Capsule use was positively associated with being female in Japan and Mexico, younger age in Japan, Republic of Korea and Malaysia, high education in Brazil, Japan and Mexico, non-daily smoking in Republic of Korea, and having plans to quit in Japan and Republic of Korea. There was no consistent pattern of consumer perceptions of brand harmfulness.

    CONCLUSION: Our study documented the high prevalence of FCCs in some countries, pointing to the need to develop and implement regulatory strategies to control these attractive products.

    Matched MeSH terms: Mexico/epidemiology
  19. Kofi AE, Hakim HM, Khan HO, Ismail SA, Ghansah A, Haslindawaty ARN, et al.
    Data Brief, 2020 Aug;31:105746.
    PMID: 32490095 DOI: 10.1016/j.dib.2020.105746
    Short tandem repeat (STR) loci are widely used as genetic marker for ancestral and forensic analyses. The latter application includes for paternity testing and DNA profiling of samples collected from scenes of crime and suspects. This survey provides the first dataset for 21 STR loci across the Akan population in Ghana by genotyping of 109 unrelated healthy individuals using Investigator 24plex kit. None of the STR loci screened deviated from Hardy-Weinberg equilibrium after applying Bonferroni correction. Overall, 224 unique alleles were observed with allele frequencies ranging from 0.005 to 0.518. The combined match probability, combined power of exclusion and combined power discrimination were 1 in 4.07 × 10-25, 0.999999999 and 1, respectively. Principal coordinate analysis carried out using 21 STR allele frequency data mapped the Akans with Nigerian subpopulation groups (Hausa, Igbo and Yoruba), but separated from Thais of Thailand, Chechen of Jordan and Tijuana of Mexico.
    Matched MeSH terms: Mexico
  20. Kobayashi LC, O'Shea BQ, Wixom C, Jones RN, Langa KM, Weir D, et al.
    Alzheimers Dement, 2024 Mar;20(3):1933-1943.
    PMID: 38159252 DOI: 10.1002/alz.13665
    INTRODUCTION: We conducted a cross-national comparison of the association between main lifetime occupational skills and later-life cognitive function across four economically and socially distinct countries.

    METHODS: Data were from population-based studies of aging and their Harmonized Cognitive Assessment Protocols (HCAPs) in the US, South Africa, India, and Mexico (N = 10,037; Age range: 50 to 105 years; 2016 to 2020). Main lifetime occupational skill was classified according to the International Standard Classification of Occupations. Weighted, adjusted regression models estimated pooled and country-specific associations between main lifetime occupational skill and later-life general cognitive function in men and women.

    RESULTS: We observed positive gradients between occupational skill and later-life cognitive function for men and women in the US and Mexico, a positive gradient for women but not men in India, and no association for men or women in South Africa.

    DISCUSSION: Main lifetime occupations may be a source of later-life cognitive reserve, with cross-national heterogeneity in this association.

    HIGHLIGHTS: No studies have examined cross-national differences in the association of occupational skill with cognition. We used data from Harmonized Cognitive Assessment Protocols in the US, Mexico, India, and South Africa. The association of occupational skill with cognitive function varies by country and gender.

    Matched MeSH terms: Mexico/epidemiology
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