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Saving lives together

Karen A

World Hosp Health Serv, 2015;51(1):26-30.
PMID: 26058289

Established 20 years ago with a single dialysis center assisting only 20 patients with 6 hemodialysis machines, Medicare has grown leaps and bounds to assist thousands of poor patients to obtain a highly subsidized rate for quality treatment. Millions of ringgit raised via various fundraising projects and events have been well utilized to serve the growing number of kidney patients in Malaysia who simply cannot bear the exorbitant cost of treatment. Staying true to its mission, Medicare extends its assistance to needy kidney patients and their families, who indirectly have become part of the Medicare family.

Matched MeSH terms: Cooperative Behavior*
Fulltext Cross-border Collaboration to Improve Access to Medicine: Association of Southeast Asian Nations Perspective

Lee KS, Ming LC, Lean QY, Yee SM, Patel R, Taha NA, et al.

J Epidemiol Glob Health, 2019 06;9(2):93-97.
PMID: 31241865 DOI: 10.2991/jegh.k.190506.001
Matched MeSH terms: Cooperative Behavior
User-driven health care - answering multidimensional information needs in individual patients utilizing post-EBM approaches: a conceptual model

Biswas R, Martin CM, Sturmberg J, Shanker R, Umakanth S, Shanker S, et al.

J Eval Clin Pract, 2008 Oct;14(5):742-9.
PMID: 19018905 DOI: 10.1111/j.1365-2753.2008.00998.x

Evidence based on average patient data, which occupies most of our present day information databases, does not fulfil the needs of individual patient-centred health care. In spite of the unprecedented expansion in medical information we still do not have the types of information required to allow us to tailor optimal care for a given individual patient. As our current information is chiefly provided in disconnected silos, we need an information system that can seamlessly integrate different types of information to meet diverse user group needs. Groups of certain individual medical learners namely patients, medical students and health professionals share the patient's need to increasingly interact with and seek knowledge and solutions offered by others (individual medical learners) who have the lived experiences that they would benefit to access and learn from. A web-based user-driven learning solution may be a stepping-stone to address the present problem of information oversupply in medicine that mostly remains underutilized, as it doesn't meet the needs of the individual patient and health professional user. The key to its success would be to relax central control and make local trust and strategic health workers feel more engaged in the project such that it is truly user-driven.

Matched MeSH terms: Cooperative Behavior
Managing dental fear and anxiety in pediatric patients: A qualitative study from the public's perspective

Hamzah HS, Gao X, Yung Yiu CK, McGrath C, King NM

Pediatr Dent, 2014 Jan-Feb;36(1):29-33.
PMID: 24717706

PURPOSE:
Internet social media offers a rich source for soliciting the public's views on health issues. This qualitative research, using You-Tube as a platform, aimed to explore the public's perspectives on management of dental fear and anxiety (DFA) in pediatric patients.

METHODS:
Using three keywords ("dental fear," "dental phobia," and "dental anxiety"), YouTube videos were searched. Twenty-seven videos related to DFA in children and adolescents were reviewed by three investigators, including a nondental layperson. Inductive thematic analysis was adopted for interpreting the data.

RESULTS:
Several strategies were considered useful for controlling DFA in pediatric patients, including: verbal and nonverbal communication to establish closeness and effective guidance (explanation, permission-seeking, reassurance, and negotiation); desensitization to dental settings and procedures; tell-show-do; positive reinforcement; distraction by imagination and thoughtful designs of clinic; and parental presence and support. Some self-coping strategies adopted by patients alleviated their DFA, such as self-reasoning and trust-building through long-term connection. Dentists' clinical competence, favorable treatment outcomes, and state-of-the-art devices and technologies (dental lasers, intraoral camera, and adapted anaesthesia method) contributed to reducing DFA.

CONCLUSIONS:
Authentic testimonials in YouTube videos endorsed and interpreted a variety of strategies adoptable by patients, parents, and dental professionals for managing children's and adolescents' dental fears and anxieties.

Matched MeSH terms: Cooperative Behavior
Global trends in chemistry research and the challenge for Malaysian scientists: a perspective review

Kumar Das, V.G.

ASM Science Journal, 2013;7(2):173-220.
MyJurnal

Malaysia is currently poised to introduce its Science, Technology and Innovation (STI) Policy and Act to bolster the nation's efforts at economic and social transformation. In championing this initiative, the Academy of Sciences Malaysia, while continuing to advise the Government on STI issues of the day, has made major strides in taking stock of the country's STI strengths in the various sectors of the economy as well as weaknesses that need to be addressed in terms of human capital development. In this article, the author examines the level of research expertise presently in the country in the field of chemistry, and elaborates on the four key areas of energy, catalysis and chemical synthesis, materials science and biological chemistry which will be researched globally in the next few decades that we would also need to be engaged upon to remain competitive. Intended for a wider audience than chemists alone, the descriptive sections in the article by and large belie an interdisciplinary flavour. The article also advocates the need for a more thorough road mapping exercise of the STI efforts in chemistry across the spectrum of academia and industry and makes some recommendations towards forging strong collaborations in research between the universities, public research institutes and the industry which are seen as vital in providing cross-cutting chemical solutions throughout the value chains and to the success of technologies identified as critical to the nation.

Matched MeSH terms: Cooperative Behavior
Validation of the Physician-Pharmacist Collaborative Index for physicians in Malaysia

Sellappans R, Ng CJ, Lai PS

Int J Clin Pharm, 2015 Dec;37(6):1242-9.
PMID: 26408408 DOI: 10.1007/s11096-015-0200-6

BACKGROUND: Establishing a collaborative working relationship between doctors and pharmacists is essential for the effective provision of pharmaceutical care. The Physician-Pharmacist Collaborative Index (PPCI) was developed to assess the professional exchanges between doctors and pharmacists. Two versions of the PPCI was developed: one for physicians and one for pharmacists. However, these instruments have not been validated in Malaysia.
OBJECTIVE: To determine the validity and reliability of the PPCI for physicians in Malaysia.
SETTING: An urban tertiary hospital in Malaysia.
METHODS: This prospective study was conducted from June to August 2014. Doctors were grouped as either a "collaborator" or a "non-collaborator". Collaborators were doctors who regularly worked with one particular clinical pharmacist in their ward, while non-collaborators were doctors who interacted with any random pharmacist who answered the general pharmacy telephone line whenever they required assistance on medication-related enquiries, as they did not have a clinical pharmacist in their ward. Collaborators were firstly identified by the clinical pharmacist he/she worked with, then invited to participate in this study through email, as it was difficult to locate and approach them personally. Non-collaborators were sampled conveniently by approaching them in person as these doctors could be easily sampled from any wards without a clinical pharmacist. The PPCI for physicians was administered at baseline and 2 weeks later.
MAIN OUTCOME MEASURE: Validity (face validity, factor analysis and discriminative validity) and reliability (internal consistency and test-retest) of the PPCI for physicians.
RESULTS: A total of 116 doctors (18 collaborators and 98 non-collaborators) were recruited. Confirmatory factor analysis confirmed that the PPCI for physicians was a 3-factor model. The correlation of the mean domain scores ranged from 0.711 to 0.787. "Collaborators" had significantly higher scores compared to "non-collaborators" (81.4 ± 10.1 vs. 69.3 ± 12.1, p < 0.001). The Cronbach alpha for the overall PPCI for physicians was 0.949, while the Cronbach alpha values for the individual domains ranged from 0.877 to 0.926. Kappa values at test-retest ranged from 0.553 to 0.752.
CONCLUSION: The PPCI for physicians was a valid and reliable measure in determining doctors' views about collaborative working relationship with pharmacists, in Malaysia.

Matched MeSH terms: Cooperative Behavior*
Fulltext Surveillance for sarcocystosis in Tioman Island, Malaysia

Husna Maizura, A.M., Khebir, V., Chong, C.K., Azman Shah, A.M., Azri, A., Lokman Hakim S.

Malaysian Journal of Public Health Medicine, 2012;12(2):39-44.
MyJurnal

In October 2011, the National International Health Regulations (IHR) 2005 Focal Point for Malaysia received notification from the United States’ Centers for Disease Control and Prevention (CDC) of a probable Sarcocystis outbreak amongst 23 travellers from six countries who had vacationed on Tioman Island between June and August 2011. The Ministry of Health, Malaysia (MOH) in collaboration with the Department of Veterinary Services, Malaysia (DVS) conducted a cross sectional study in November 2011 to determine the presence of Sarcocystosis among humans, animals and in the environment in Tioman Island. Epidemiological investigations conducted involved a community health survey of 44 residents in Kampung Salang, Tioman and review of outpatient attendance cards for suspected or confirmed cases of Sarcocystosis. Twenty-eight fresh stool samples were collected and sent to the National Public Health Laboratory (NPHL) for detection of Sarcocystis oocysts using fluorescence microscopy. Water samples taken from 27 water sampling points around the island were processed and analysed under the fluorescence microscope using ultraviolet (UV) light at the Institute for Medical Research (IMR) to detect the presence of Sarcocystis sporocyst. DVS collected 84 faecal samples from four types of domesticated animals and then analysed them at the Veterinary Services Centre in Tioman Island for Sarcocystis oocysts and other parasitic ova and cysts using qualitative Floatation Technique. The results showed that Sarcocystis was not present in humans, animals and in the environment in Tioman Island during the study period. Further surveillance among humans, wildlife and the environment is needed to determine Sarcocystis endemicity in Tioman Island.

Matched MeSH terms: Cooperative Behavior
Fulltext Elder Abuse: A Silent Cry

Esther, E., Shahrul, K., Low, W.Y.

Malaysian Journal of Psychiatry, 2006;14(1):29-34.
MyJurnal

\Elderly abuse exists in our society but is hardly ever reported. This problem often remains undetected because of poor public awareness and lack of knowledge among health care personnel. This article addresses the definition of elderly abuse, characteristics of the abused elderly and their abusers as well as strategies to detect and manage it. Collaboration between health care professionals and government bodies is needed to identify and manage elderly abuse. Ultimately, a legislative "Elder Protective Act" should be implemented to safeguard the rights of our vulnerable elderly.

Matched MeSH terms: Cooperative Behavior
Professional pharmacist organizations--their role in the development of Australian pharmacists within General Practitioner Super Clinics

Poulsen JH, Kaae S, Mak V

Res Social Adm Pharm, 2014 Sep-Oct;10(5):807-8.
PMID: 24986542 DOI: 10.1016/j.sapharm.2014.05.002
Matched MeSH terms: Cooperative Behavior
Fulltext Pharmacogenomics in drug therapy and interaction: the role of cytochrome P450

Ong, Chin-Eng, Yan, Pan, Tiong, Kai-Hung, Yiap, Beow-Chin, Tan, Eng-Lai, Pook, Peter, et al.

International e-Journal of Science, Medicine & Education, 2008;2(3):-.
MyJurnal

Pharmacogenomics (or pharmacogenetics), the study of the effects of genetic differences on a person’s response to drugs, can help in optimizing drug efficacy and minimizing adverse drug reactions. Interperson difference in drug metabolism is one of the important consequences of such genetic variation. This variation is determined in part by mutations in cytochrome P450 enzymes (CYPs). IMU is part of a major collaborative research project in the area of phamacogenetics and drug metabolism. Working together with USM and UiTM, our group has, since 2000, generated useful population database on genetic polymorphism of various CYP isoforms. We have successfully genotyped three major ethnic groups, Malay, Indian and Chinese for their allelic frequency of important isoforms. These include CYP2D6, CYP2C9, CYP2C8 and CYP2A6. Data generated so far collectively have contributed to our effort in mapping and constructing genomic database for Malaysian population.
Since early 2002, our research has been focusing on developing in vitro methods in studying the functional consequences of genetic polymorphism of CYP enzymes. Using site-directed mutagenesis, CYP mutants, carrying nucleotide changes as reported in known alleles in human populations, were generated and expressed in E. coli system, and the expressed recombinant proteins were characterized using enzyme assays to determine the functional consequences of mutations. We have established a series of HPLC (high performance liquid chromatography)-based and fluorescence-based assays to investigate CYP activities. Assays that have been developed include tolbutamide methylhydroxylase, paclitaxel 6α-hydroxylase, dextromethorphan O-demethylation, testosterone 6β-hydroxylation and coumarin 7-hydroxylase assays. These assays serve as activity markers allowing comparison of catalytic activities of mutant proteins generated. Another focus of our work is to use the developed assays as a screening tool to investigate drug-herb interactions. This was achieved by co-incubation of herbal extracts and active constituents with the probe substrates in the assays followed by characterization of the kinetic behaviors of the enzymes involved using various pharmacokinetic parameters such as Km, Vmax, IC50 and Ki. This work is currently carried out with collaboration from the Institute for Medical Research (IMR) and is supported by MOSTI’s eScienceFund under RM9. It is envisaged that this screening work will give us insights on the potential of the commonly used herbs to cause pharmacokinetic interactions with other drug substrates, and allow us to elucidate the mechanisms involved in the interactions.

Matched MeSH terms: Cooperative Behavior
Collaborative off-shore nurse education: an Australian initiative

Jones B, Serrell M, Maltby H

Nurse Educ, 2000 10 29;25(2):57, 69.
PMID: 11051998
Matched MeSH terms: Cooperative Behavior
Fulltext Isu dan cabaran yang dihadapi oleh pasukan perubatan dan kesihatan semasa bencana banjir di daerah Muar dan Keluang Johor

Zuhaida, A.J., Maznisham, M.S.

Malaysian Journal of Community Health, 2009;15(3):60-67.
MyJurnal

Introduction : Flood disaster in Johor started at the end of 2006 until the early year of 2007 causing the distruction of property and human life and it was the worse flood disaster in the history of Malaysia. The Muar and Kluang Health Office had been taken all the measures in the District Plan of Action for flood disaster in the early phase of the flood. Management of the Health and Medical team was one of the measures taken for the deployment of staff systematically and optimumly use of man power during a disaster.
Metodology : The objective for this article is to share the experience regarding human resource management during flood disaster. Data collected base on flood activities rosters used by health staff during morning briefing, analysis of record and daily flood report, interviewing the staff and flood victim involved regarding the experience and challengers they face and lastly by observing the services given to flood victim during the disasters.
Finding : There were 41 Medical and Health Team formed and responsible at 108 flood relived centre homing 26,824 flood victims in Muar District while in Kluang, 21 Medical and health Team were providing services in 60 flood relieve centre with 36,126 flood victims. All of the activities conducted by the Medical and Health team were coordinated by the district flood operation centre. District of Muar had been receiving 16 additional staff from other state while 34 additional staff had been providing services in Kluang. Challengers that had been identified include shortage of human resource compared to the increasing need and task during the flood disaster, shortage of personal protective equipments, frequent changers and inconsistency in the format use during flood reporting and lack of psychosocial support and motivation among the staff involved in the flood disaster operation.
Conclusion : Partnership among other department are very importance and the collaboration between them were very good.

Matched MeSH terms: Cooperative Behavior
Fulltext Collaboration at the Departmental, School, National and International Levels at the International Medical University, Kuala Lumpur

Michael John Rathbone

International e-Journal of Science, Medicine & Education, 2013;7(11):57-64.
MyJurnal

The nature, extent and definition of a collaboration varies between individuals, disciplines, departments and institutions. It depends upon such factors as the people involved, the nature of the research problem, the research environment, the institutional culture and demographic factors. This paper will examine the concept of collaborative research and discuss its place and position in an evolving university.

Matched MeSH terms: Cooperative Behavior
Fulltext Fostering critical thinking and collaborative learning skills among medical students through a research protocol writing activity in the curriculum

Sahoo S, Mohammed CA

Korean J Med Educ, 2018 Jun;30(2):109-118.
PMID: 29860777 DOI: 10.3946/kjme.2018.86

PURPOSE: This intervention was aimed to analyse the effect of academic writing and journal critiquing as educational approaches in improving critical thinking and collaborative learning among undergraduate medical students.
METHODS: A research proposal writing format was created for the 4th year medical students of Melaka Manipal Medical College, Malaysia during their ophthalmology clinical postings. The students worked in small groups and developed research protocols through an evidence based approach. This was followed by writing reflective summaries in academic portfolios about the activity undertaken. A mixed methods study was designed to explore the possible role of collaborative research proposal writing in enhancing critical thinking and collaborative learning.
RESULTS: Analysis of reflections submitted by 188 medical students after the intervention indicate that majority of them found an improvement in their skills of critical thinking and collaborative learning as a result of research protocol writing. All participants agreed that the model helped in applying concepts to new situations in the form of designing their own study, which reflected in enhanced higher order cognitive skills.
CONCLUSION: This study shows that the introduction of a structured module in the core medical curriculum that focuses on research writing skills embedded with collaborative and reflective practices can enhance collaborative learning, critical thinking, and reasoning among medical students.

Matched MeSH terms: Cooperative Behavior*
The use of jigsaw learning technique in teaching medical students prescribing skills

Sim SM, Foong CC, Tan CH, Lai PS, Chua SS, Mohazmi M

Med Teach, 2014 Feb;36(2):182.
PMID: 24156275 DOI: 10.3109/0142159X.2013.848977
Matched MeSH terms: Cooperative Behavior*
Review article: Use of renal registry data for research, health-care planning and quality improvement: what can we learn from registry data in the Asia-Pacific region?

Lim TO, Goh A, Lim YN, Morad Z

Nephrology (Carlton), 2008 Dec;13(8):745-52.
PMID: 19154324 DOI: 10.1111/j.1440-1797.2008.01044.x

We review renal registry data from the Asia-Pacific region with an emphasis on their uses in health care and in dialysis care in particular. The review aims to demonstrate the information value of registry data. While renal registry provides a useful data resource for epidemiological research, there are severe methodological limitations in its application for analytical or therapeutic research. However, it is the use of renal registry data for public health and health-care management purposes that registry really comes into its own, and it is primarily for these that governments have invested in national patient and disease registries. We apply data from several renal registries in the Asia-Pacific region to illustrate its wide application for planning dialysis services, for evaluating dialysis practices and health outcomes, with a view to improving the quality of dialysis care. In the course of preparing the review, we have found that the quality and accessibility of renal registry data were highly variable across the region. Given the value of renal registry, every country in the Asia-Pacific region should establish one or should ensure that their current registries are better resourced and developed. Greater data sharing and collaboration among registries in the region could help advance the nephrology to serve our patients better.

Matched MeSH terms: Cooperative Behavior
Fulltext Multi-format information fusion through integrated metadata using hybrid ontology for disaster management

Che Mustapha Yusuf, J., Mohd Su’ud, M., Boursier, P., Muhammad, A.

Pertanika Journal of Science & Technology, 2013;21(1):217-226.
MyJurnal

Finding relevant disaster data from a huge metadata overhead often results in frustrating search
experiences caused by unclear access points, ambiguous search methods, unsuitable metadata, and long response times. More frequently, semantic relation between the retrieved objects is neglected. This paper presents a system architecture that makes use of ontologies in order to enable semantic metadata descriptions for gathering and integrating multi-format documents in the context of disaster management. After a brief discussion on the challenges of the integration process, the Multi-format Information Retrieval, Integration and Presentation (MIRIP) architecture is presented. A specific approach for ontology development and mapping process is introduced in order to semantically associate user’s query and documents metadata. An ontology model approach was designed to follow inspirational and collaborative approaches with top-down to bottom-up implementation. A prototype of the integrated disaster management information system is currently under development, based on the architecture that is presented in this paper.

Matched MeSH terms: Cooperative Behavior
Fulltext The foundation of NCVD PCI Registry: the Malaysia's first multi-centre interventional cardiology project

Liew HB, Rosli MA, Wan Azman WA, Robaayah Z, Sim KH, NCVD PCI investigators

Med J Malaysia, 2008 Sep;63 Suppl C:41-4.
PMID: 19230246

The National Cardiovascular Database for Percutaneous Coronary Intervention (NCVD PCI) Registry is the first multicentre interventional cardiology project, involving the main cardiac centres in the country. The ultimate goal of NCVD PCI is to provide a contemporary appraisal of PCI in Malaysia. This article introduces the foundation, the aims, methodology, database collection and preliminary results of the first six-month database.

Matched MeSH terms: Cooperative Behavior
An Integrated Systems Approach is Needed to Ensure the Sustainability of Antibiotic Effectiveness for Both Humans and Animals

So AD, Shah TA, Roach S, Ling Chee Y, Nachman KE

J Law Med Ethics, 2015;43 Suppl 3:38-45.
PMID: 26243242 DOI: 10.1111/jlme.12273

The growing demand for animal products and the widespread use of antibiotics in bringing food animals to market have heightened concerns over cross-species transmission of drug resistance. Both the biology and emerging epidemiology strongly support the need for global coordination in stemming the generation and propagation of resistance, and the patchwork of global and country-level regulations still leaves significant gaps. More importantly, discussing such a framework opens the door to taking modular steps towards solving these challenges - for example, beginning among targeted parties rather than all countries, tying accountability to financial and technical support, or taxing antibiotic use in animals to deter low-value usage of these drugs. An international agreement would allow integrating surveillance data collection, monitoring and enforcement, research into antibiotic alternatives and more sustainable approaches to agriculture, technical assistance and capacity building, and financing under the umbrella of a One Health approach.

Matched MeSH terms: Cooperative Behavior*
Birth Cohort Consortium of Asia: Current and Future Perspectives

Kishi R, Zhang JJ, Ha EH, Chen PC, Tian Y, Xia Y, et al.

Epidemiology, 2017 10;28 Suppl 1:S19-S34.
PMID: 29028672 DOI: 10.1097/EDE.0000000000000698

BACKGROUND: The environmental health of children is one of the great global health concerns. Exposures in utero and throughout development can have major consequences on later health. However, environmental risks or disease burdens vary from region to region. Birth cohort studies are ideal for investigating different environmental risks.
METHODS: The principal investigators of three birth cohorts in Asia including the Taiwan Birth Panel Study (TBPS), the Mothers and Children's Environmental Health Study (MOCEH), and the Hokkaido Study on Environment and Children' Health (Hokkaido Study) coestablished the Birth Cohort Consortium of Asia (BiCCA) in 2011. Through a series of five PI meetings, the enrolment criteria, aim of the consortium, and a first-phase inventory were confirmed.
RESULTS: To date, 23 birth cohorts have been established in 10 Asian countries, consisting of approximately 70,000 study subjects in the BiCCA. This article provides the study framework, environmental exposure and health outcome assessments, as well as maternal and infant characteristics of the participating cohorts.
CONCLUSIONS: The BiCCA provides a unique and reliable source of birth cohort information in Asian countries. Further scientific cooperation is ongoing to identify specific regional environmental threats and improve the health of children in Asia.

Matched MeSH terms: Cooperative Behavior*

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