Displaying publications 41 - 60 of 910 in total

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  1. What worries first-year students? Psychometric properties of the Student Worry Scale
    Fam JY, Murugan SB, Yap CYL
    Scand J Psychol, 2020 Jun;61(3):410-415.
    PMID: 32086948 DOI: 10.1111/sjop.12627
    The transition to university can be stressful for first-year university students. Despite the fact where the feeling of worry is a shared symptom by various mental health issues, there is a lack of studies that investigate into this matter. As worry is a domain-specific construct, there is a need for a valid and reliable measure of worry specifically for university students. Hence, this study aimed to evaluate the psychometric properties of the Student Worry Scale (SWS), particularly in terms of its validity and reliability. For this purpose, the current study recruited a sample of 295 first-year students to evaluate the psychometric properties of SWS. Exploratory factor analysis yielded a five-factor structure of SWS, which explained 55.7% of the total variance. The yielded five factors were general worries, financial-related concerns, significant other's well-being, academic concerns, and social adequacy concerns. Inter-correlations between the five factors were all significant (r ranged between 0.395 and 0.625). The SWS demonstrated good internal consistency in this study (Cronbach's alpha ranged between 0.786 and 0.941). Overall, the SWS is psychometrically evidenced to be a reliable and valid content-based worry measure specifically for university students.
    Matched MeSH terms: Universities
  2. Unethical Admissions: Academic Integrity in Question
    Ansah RH, Aikhuele DO, Yao L
    Sci Eng Ethics, 2017 08;23(4):1237-1239.
    PMID: 27896603 DOI: 10.1007/s11948-016-9815-9
    The increasing unethical practices of graduates' admissions have heightened concerns about the integrity of the academy. This article informs this important subject that affects the students, admission systems, and the entire scientific community, thus, representing an approach against scholarly black market activities including falsified documents and unethical practices by consultants and students' recruitment agencies.
    Matched MeSH terms: Universities/ethics*
  3. Viva Delay
    Yahaghi H, Sorooshian S, Yahaghi J
    Sci Eng Ethics, 2017 06;23(3):945-946.
    PMID: 27351770 DOI: 10.1007/s11948-016-9795-9
    The time delay between submission of a thesis and Viva Voce is intolerable for students. This letter tries to draw the readers' attention to the effect of choosing the right examiner, in order to reduce the Viva Voce delay.
    Matched MeSH terms: Universities/trends; Universities/statistics & numerical data; Universities/ethics*
  4. Fulltext Lecturer, student and patient’s experience toward simulated patient programmed: “we all play a role”
    GOH, LAY-KHIM, YEE, BIT-LIAN
    Malaysian Journal of Qualitative Research, 2019;5(1):5-17.
    MyJurnal
    Simulated Patient (SP) is defined as a layperson that simulates to portray the role of a patient with health-related conditions based on varying levels of training. International Medical University (IMU) has been utilising SP for more than 10 years for simulation activities including learning sessions and examination. Due to a series of complex interaction within the SP programme, the aim of the study was to explore the experience of lecturer, student and SPs towards the interaction within the SP programme. The findings of the research were aimed to improve the teaching sessions and examination through the improvement of the SP programme. A total of 17 participants were recruited for 6 interviews, including both focus group and one-to-one interview session. The researcher used a list of guide questions to explore both positive and negative experiences. Manual transcribing and coding technique were used for data analysis, while Qualitative Data Analysis (QDA) was used for data management and additional analysis. The themes for the lecturer group were: SP resemble a real patient, The making of scenario, and SP feedback; while the themes for the students group were: Simulated patient as an effective learning tool, Fairness, and Feedback from simulated patient; whereas Effective learning session, Motivation and Preparation prior class were the themes for the SP group. SPs’ contribution was valuable if the SP is able to resemble a real patient and able to demonstrate effective feedback skills. Standardisation of the character portrayal and SP feedback influenced the fairness along the students’ journey. Lecturers, SPs and students influenced the success of an SP-based simulation session.
    Matched MeSH terms: Universities
  5. Fulltext Mediating Role of Intra-Team Conflict between Paternalistic Leadership and Decision-Making Quality among China University's CMT during COVID-19
    Cheah KSL, Abdullah Z, Xiao M
    Int J Environ Res Public Health, 2022 Sep 16;19(18).
    PMID: 36141967 DOI: 10.3390/ijerph191811697
    Universities across China have set up crisis management teams (CMTS) to deal with the crisis brought on by the COVID-19 pandemic. This study focuses on how the paternalistic leadership practices of a Chinese university CMT influence crisis strategic decisions by managing conflict. These relationships were verified using hierarchical regression analysis on 312 samples from the surveyed university during the pandemic and found the following: benevolent leadership and moral leadership have positive effects on decision quality. However, unlike most studies on paternalistic leadership, in crisis situations, the negative effects of authoritarian leadership disappear under the mediating effect of affective conflict. This means that affective conflict within CMT fully mediates the relationship between authoritarian leadership and decision quality, and partially mediates the relationship between moral leadership and decision quality, while cognitive conflict partially mediates the relationship between benevolent leadership and crisis decision quality. It indicates that a CMT must stimulate and maintain a certain level of cognitive conflict while suppressing affective conflict to achieve high-quality crisis decision-making. This state can be achieved by practicing lower levels of authoritarian leadership and maintaining high levels of moral and benevolent leadership practices.
    Matched MeSH terms: Universities
  6. May Measurement Month 2018: an analysis of blood pressure screening results from Malaysia
    Chia YC, Ching SM, Devaraj NK, Chew BN, Ooi PB, Mohamed M, et al.
    Eur Heart J Suppl, 2020 Aug;22(Suppl H):H83-H85.
    PMID: 32884479 DOI: 10.1093/eurheartj/suaa035
    Hypertension continues to be the top global killer, contributing to over 10 million deaths annually. As prevalence and unawareness of hypertension remain high in Malaysia, this study was aimed to screen more individuals to identify those with undiagnosed hypertension. Respondents aged ≥18 years were recruited through opportunistic sampling at various screening sites including health clinics, hospitals, student health centres, universities, community halls, shopping malls, as well as through other health screening campaigns. Each respondent completed a questionnaire on socio-demographic, environmental, and lifestyle data. Anthropometric measurements as well as three blood pressure (BP) measurements were obtained from all participants. Hypertension was defined as a systolic BP ≥140 mmHg and/or diastolic BP ≥90 mmHg or taking antihypertensive medication. The total number of participants was 4866. The mean age of the participants was 39.8 (17.6) years with 61.1% female participants. Of the 4866 participants, 1405 (28.9%) had hypertension. The proportion of those aware of their hypertension status was 76.3% (1073/1405). The proportion of those with hypertension on medication was 71% (998/1405). Of those receiving antihypertensive treatment, 62.4% (623/998) had controlled BP. The proportion of hypertension in this study was 28.9%. The awareness rate of 76.3% compares favourably to a previously reported national level of 43.2%. Hence, BP screening programmes may be effective at increasing awareness and should be conducted annually.
    Matched MeSH terms: Universities
  7. The mediating effect of Internet gaming disorder's symptoms on loneliness and aggression among undergraduate students and working adults in Malaysia
    T'ng ST, Ho KH, Sim DE, Yu CH, Wong PY
    Psych J, 2020 Feb;9(1):96-107.
    PMID: 31797557 DOI: 10.1002/pchj.320
    Insufficient attention has been given to the integration of the mediating effect of Internet gaming disorder (IGD) symptoms on loneliness and four components of aggression-physical aggression, verbal aggression, anger, and hostility-in the Malaysian context. In the present study, 410 participants with (a) at least 1 year of Internet gaming experience and (b) between ages 20- to 39 years were recruited using the probability proportional to size sampling method. Participants were undergraduate students and working adults. Self-reported questionnaires (the Internet Gaming Disorder Scale, University of California, Los Angeles Loneliness Scale, and the Buss-Perry Aggression Questionnaire) were used. The present study found that loneliness positively predicted four components of aggression (i.e., anger, hostility, physical aggression, and verbal aggression) and symptoms of IGD. Relationships between loneliness and the four components of aggression were partially mediated by IGD symptoms. The present study enriches and consolidates existing empirical evidence, particularly in the Malaysian context. If the mediating effect is not emphasized, it may lead to spurious conclusions that can significantly diminish the effectiveness of interventions that are meant to manage aggression.
    Matched MeSH terms: Universities
  8. Fulltext Perceived risks, barriers and stages of change on smoking cessation among The Malay security guards in a public university in Kuala Lumpur.
    Moy FM, Atiya AS, Wong ML
    International Medical Journal Malaysia, 2008;7(2):9-14.
    MyJurnal
    Introduction: The objective was to evaluate the perceived risks, barriers and stages of change on smoking cessation among the Malay male security guards. Materials and Methods: In the year 2004, a cross sectional survey was conducted on a group of security guards working in the campus and the hospital of a public university in Kuala Lumpur. Universal sampling (n=210) was conducted with a response rate of 88.6%. A self-administered questionnaire was used to survey the participants on their smoking status, stages of change, perceived risks and barriers to smoking cessation. Results: There were 37% current smokers and 23.7% ex-smokers. The mean year of smoking was 19.2 + 8.1 and the number of cigarettes smoked was 16.4 + 8.0 per day among the current smokers. About two-third of the smokers perceived the amount smoked currently was bad for health. However, only 23.3% and 30.9% of the smokers perceived themselves to be at higher risk for lung cancer and heart disease respectively. The three main reasons to quit smoking were health reasons, doctors’ advice and cost. The main barriers were addiction (53.3%) and stress (28.3%). Most of the smokers (42%) were in the pre-contemplation stage with half of them not having thoughts of quitting. Conclusion: The smokers had misperception on smoking and majority was at the pre-contemplation stage of change in smoking cessation. The findings of this survey add on to the existing literature about the perception of risks, barriers and stages of change to smoking cessation. This will provide valuable information on the planning and delivering of smoking cessation programmes in the local context.
    Matched MeSH terms: Universities
  9. The results of a worksite health promotion programme in Kuala Lumpur, Malaysia
    Moy F, Sallam AA, Wong M
    Health Promot Int, 2006 Dec;21(4):301-10.
    PMID: 16963785
    The worksite is one of the key channels for the delivery of interventions to reduce chronic diseases among adult populations. It provides easy and regular access to a relatively stable population and it encourages sustained peer support. This paper reports a 2-year follow-up of the impact of a worksite health promotion programme on serum cholesterol and dietary changes among employees in a city in Malaysia. A quasi-experimental study was conducted among Malay-Muslim male security guards, with those working in a public university in Kuala Lumpur comprising the intervention group, and those working in the teaching hospital of the same university as the comparison group. They were comparable in socio-demographic characteristics. The intervention group received intensive individual and group counselling on diet, physical activity and quitting smoking. The comparison group was given minimal education on the same lifestyle changes through mail and group counselling. The intervention group showed a statistically significant reduction in their mean total cholesterol levels as compared with the comparison group, with an intervention effect of -0.38 (95% CI = -0.63, -0.14) mmol/l. The intervention group also reported a reduction in the amount of cigarettes smoked. The worksite was shown to be an effective channel for health promotion. The adoption of the new lifestyle behaviours should be supported and sustained through modification of work policies.
    Matched MeSH terms: Universities/organization & administration*
  10. Fulltext An exploration of knowledge, attitudes and behaviours of young multiethnic Muslim-majority society in Malaysia in relation to reproductive and premarital sexual practices
    Wong LP
    BMC Public Health, 2012;12:865.
    PMID: 23057505 DOI: 10.1186/1471-2458-12-865
    BACKGROUND: The increasing trend of premarital sexual experience and unintended pregnancies in Malaysia warrants sustained and serious attention. The sensitivities of sex-related issues in a Muslim-majority country create various types of barriers to sexual and reproductive health information, support and practices. This study aims to gain understanding of knowledge, attitudes and behaviours of young women in Malaysia concerning reproductive, contraception and premarital sexual practices.
    METHODS: A cross-sectional study was performed, using an anonymous self-administered questionnaire carried out among 1695 female university students in a public university in Malaysia.
    RESULTS: Respondents had low scores for knowledge of reproduction and pregnancy (median=4, of maximum score 10), contraceptive uses (median=6, of maximum score 16) and contraceptive availability (median=3, of maximum score 13). The majority of women surveyed do not have liberal values in relation to premarital sexual behaviour (median=37, of maximum 40); higher scores on this scale corresponded to opposing premarital sex. The multivariate analyses showed that ethnic group was the strongest correlate of knowledge and attitude scores; being of Malay Muslim ethnicity was associated significantly with lower knowledge scores and premarital sex permissiveness. Other significant correlates were year of study, maternal occupational groups, level of religious faith, dating status and urban-rural localities. Level of premarital sex permissiveness was inversely correlated with reproduction and pregnancy knowledge score, and contraceptive knowledge scores.
    CONCLUSION: Reproductive health knowledge and attitudes were intricately linked to religious values and cultural norms differences surrounding sexual issues.
    Matched MeSH terms: Universities
  11. Fulltext Dietary supplements: usage and opinions among health sciences students
    Teng CL, Tey KK, Lim PH, Cheng SF, Nordin MS, Ng CM, et al.
    International e-Journal of Science, Medicine & Education, 2008;2(2):30-32.
    MyJurnal
    This is a questionnaire survey of dietary supplement usage among students in the International Medical University. Just over two-fifths of these students reported using dietary supplements daily. This high usage of dietary supplements is in contrast their expressed ambivalence about these products.
    Matched MeSH terms: Universities
  12. Fulltext Comparative bioavailability study of a generic sustained release diclofenac sodium tablet
    Magosso E, Yuen KH, Choy WP, Ling SSN, Ng BH, Ur-Rahman N, et al.
    Med J Malaysia, 2004 Aug;59(3):352-6.
    PMID: 15727381
    The bioavailability of a generic diclofenac sodium sustained release tablet preparation (Zolterol, SR) was compared with the innovator product, Voltaren, SR. Twelve healthy adult male volunteers participated in the study, which was conducted according to a randomized, two-way crossover design with a wash out period of one week. The bioavailability of diclofenac was compared using the parameters area under the plasma concentration-time curve (AUC(0-infinity)), peak plasma concentration (Cmax) and time to reach peak plasma concentration (Tmax). No statistically significant difference was observed for both logarithmically transformed AUC(0-infinity), Cmax values and Tmax value of the two preparations.
    Matched MeSH terms: Universities
  13. Assessing oral cancer awareness among dental and medical students of a Malaysian private university
    Gunjal S, Pateel DGS, Lim RZS, Yong LL, Wong HZ
    Int Dent J, 2020 Feb;70(1):62-69.
    PMID: 31691268 DOI: 10.1111/idj.12524
    OBJECTIVE: Dental and medical practitioners play a pivotal role in detecting early stages of oral cancers. Hence, future dental and medical practitioners need to have adequate knowledge of oral cancer. This study was conducted to assess the current level of knowledge, attitude and practices regarding oral cancer among dental and medical students of a Malaysian private university.

    METHODS: A cross-sectional study was conducted on third-, fourth- and final-year students of the dental and medical courses of MAHSA University, Malaysia. A total of 557 students participated in the survey. Oral cancer awareness, knowledge about risk factors, signs and symptoms of oral cancer, attitude and practices towards oral cancer were assessed using 43 questions. The questionnaire was pretested, and internal consistency, assessed using Cronbach's alpha, was acceptable (α > 0.7). The data were analysed using IBM SPSS version 21. The chi-square test was used to analyse the difference in oral cancer awareness between medical and dental students.

    RESULTS: Among 557 participants, there were 351 (63%) medical students and 206 (37%) dental students. Based on the results obtained, dental students had a higher level of knowledge than medical students regarding oral cancer (P 

    Matched MeSH terms: Universities
  14. Fulltext Quality assurance in education: perception of undergraduate health professions students in a Malaysian university
    Er HM, Nadarajah VD, Ng SH, Wong AN
    Korean J Med Educ, 2020 Sep;32(3):185-195.
    PMID: 32723985 DOI: 10.3946/kjme.2020.166
    PURPOSE: Direct student involvement in quality processes in education has been suggested to encourage shared responsibilities among faculty and students. The objectives of this study were to explore undergraduate health professions students' understanding of quality assurance (QA) in education, and identify the challenges and enablers for student involvement in an Asian context.

    METHODS: Twenty semi-structured interviews were conducted among medical, dentistry, and pharmacy students in a Malaysian University. The interviews were audio-recorded, transcribed verbatim, and thematically analyzed to understand the students' perspectives of QA in education.

    RESULTS: The participants recognized the importance of QA towards ensuring the quality of their training, which will consequently impact their work readiness, employability, and quality of healthcare services. Academic governance, curriculum structure, content and delivery, faculty and student quality, teaching facilities, and learning resources were indicated as the QA areas. The challenges for students' involvement included students' attitude, maturity, and cultural barrier. To enhance their buy-in, clear objectives and impact, efficient QA mechanism, and recognition of students' contribution had been suggested.

    CONCLUSION: The findings of this study support student-faculty partnership in QA processes and decision making.

    Matched MeSH terms: Universities
  15. Reflections on a decade of research by ASEAN dental faculties: analysis of publications from ISI-WOS databases from 2000 to 2009
    Sirisinha S, Koontongkaew S, Phantumvanit P, Wittayawuttikul R
    J Investig Clin Dent, 2011 May;2(2):72-80.
    PMID: 25426599 DOI: 10.1111/j.2041-1626.2011.00048.x
    This communication analyzed research publications in dentistry in the Institute of Scientific Information Web of Science databases of 10 dental faculties in the Association of South-East Asian Nations (ASEAN) from 2000 to 2009. The term used for the "all-document types" search was "Faculty of Dentistry/College of Dentistry." Abstracts presented at regional meetings were also included in the analysis. The Times Higher Education System QS World University Rankings showed that universities in the region fare poorly in world university rankings. Only the National University of Singapore and Nanyang Technological University appeared in the top 100 in 2009; 19 universities in the region, including Indonesia, Malaysia, the Philippines, Singapore, and Thailand, appeared in the top 500. Data from the databases showed that research publications by dental institutes in the region fall short of their Asian counterparts. Singapore and Thailand are the most active in dental research of the ASEAN countries.
    Matched MeSH terms: Universities
  16. Fulltext The implementation of problem-based learning in collaborative groups in a chiropractic program in Malaysia
    Win NN, Nadarajah VD, Win DK
    J Educ Eval Health Prof, 2015;12:17.
    PMID: 25961676 DOI: 10.3352/jeehp.2015.12.17
    PURPOSE: Problem-based learning (PBL) is usually conducted in small-group learning sessions with approximately eight students per facilitator. In this study, we implemented a modified version of PBL involving collaborative groups in an undergraduate chiropractic program and assessed its pedagogical effectiveness.
    METHODS: This study was conducted at the International Medical University, Kuala Lumpur, Malaysia, and involved the 2012 chiropractic student cohort. Six PBL cases were provided to chiropractic students, consisting of three PBL cases for which learning resources were provided and another three PBL cases for which learning resources were not provided. Group discussions were not continuously supervised, since only one facilitator was present. The students' perceptions of PBL in collaborative groups were assessed with a questionnaire that was divided into three domains: motivation, cognitive skills, and perceived pressure to work.
    RESULTS: Thirty of the 31 students (97%) participated in the study. PBL in collaborative groups was significantly associated with positive responses regarding students' motivation, cognitive skills, and perceived pressure to work (P<0.05). The students felt that PBL with learning resources increased motivation and cognitive skills (P<0.001).
    CONCLUSION: The new PBL implementation described in this study does not require additional instructors or any additional funding. When implemented in a classroom setting, it has pedagogical benefits equivalent to those of small-group sessions. Our findings also suggest that students rely significantly on available learning resources.
    KEYWORDS: Chiropractic; Learning; Motivation; Perception; Problem-based learning
    Matched MeSH terms: Universities
  17. Fulltext Investigating the psychometric properties of the Jefferson Scale of Physician Empathy in a sample of Malaysian medical students
    Spasenoska M, Costello S, Williams B
    Adv Med Educ Pract, 2016;7:331-9.
    PMID: 27350763 DOI: 10.2147/AMEP.S96591
    OBJECTIVE: The purpose of this present study was to investigate the psychometric properties of the Jefferson Scale of Physician Empathy - student version (JSPE-S).
    SUBJECTS AND METHODS: This study recruited 193 Malaysian medical students enrolled in year one and year two studies. A principal-component analysis with Varimax rotation was conducted. Procrustes rotation was used to confirm the item to model fit, which allows for a comparison of actual structure against an ideal hypothesized structure. Items were systematically removed based on low communalities of < 0.3 and poor loading of items onto components.
    RESULTS: A two-component solution was found, comprised of "perspective taking" and "compassionate care". Following item removal, eleven items remained. A Procrustes analysis revealed that this eleven-item measure demonstrated an excellent model fit. A possible third component was identified, though is not recommended for use, due to construct underrepresentation.
    CONCLUSION: This study found the Jefferson Scale of Physician Empathy fitted best to a two-component model using eleven items. Item, component, and overall congruence were very high, and scale reliabilities were adequate. The results of this study suggest that the eleven-item, two-component solution demonstrates excellent psychometric properties and structural validity in a Malaysian medical student population. Future research could consider using the short eleven-item measure in both student and health care profession samples to investigate the role of empathy in health care.
    Study site:; Jeffry Cheah School of Medicine and Health Sciences, Monash University Malaysia.
    Matched MeSH terms: Universities
  18. Fulltext Awareness, Knowledge and Attitudes of Human Papillomavirus (HPV) among Private University Students- Malaysia Perspective
    Widjaja VN
    Asian Pac J Cancer Prev, 2019 07 01;20(7):2045-2050.
    PMID: 31350964 DOI: 10.31557/APJCP.2019.20.7.2045
    Objective: Assess and analyse the awareness, knowledge, and attitudes of university students regarding HPV and
    its vaccine. Methods: A cross-sectional study was designed with questionnaire serving as the research instrument.
    A total of 425 university students were recruited voluntarily. Thirteen assessable questions were analysed to reveal
    the mean total knowledge score of HPV and its vaccine. Both descriptive and statistical approach were employed
    to analyse the research outcomes. Results: Students were moderately aware as 59.8% and 49.6% have heard about
    HPV and its vaccine, respectively. The mean total knowledge score was 5.26 ± 3.10 out of 13 which was found to be
    moderately knowledgeable. Female (N= 235) have a significantly higher mean knowledge score in comparison to male
    (N= 190) at 5.58 ± 2.80 versus 4.87 ± 3.40, respectively (p<0.05), likely due to the disease profiles favouring female.
    As hypothesised, health-related school students (N= 171) outperformed other schools (N= 254) at 7.00 ± 2.95 versus
    4.10 ± 2.62, respectively (p<0.001). In general, the score depends on participant’s gender and educational background
    (χ2= 25.426, p<0.01 and χ2= 105.337, p<0.001, respectively). Despite low vaccination uptakes (28.5%), students accept
    the vaccine following physician’s recommendation and reject due to its cost. A positive attitude was seen as majority
    (88.7%) wished to know more about HPV. Conclusion: Moderation in awareness, knowledge and attitudes reflect the
    lifestyle of an urbanised population where information is accessible. Healthcare professionals, media campaign, and
    educational talk refinement are therefore essential in controlling the disease by spreading awareness.
    Matched MeSH terms: Universities/statistics & numerical data*
  19. Twelve tips for enhancing student engagement
    Peters H, Zdravkovic M, João Costa M, Celenza A, Ghias K, Klamen D, et al.
    Med Teach, 2019 06;41(6):632-637.
    PMID: 29683024 DOI: 10.1080/0142159X.2018.1459530
    Student engagement refers to a broad range of activities where students participate in management, education, research, and community activities within their institutions. It is a mutually beneficial collaborative approach between students and their institutions. This article provides practical advice for the implementation or further development of student engagement at medical, dental, and veterinary schools. The tips provided are based on the experiences of a group of universities recently recognized for best practice in student engagement, and are supported by evidence from the literature. The tips cover overarching themes which include the creation of an institutional culture and formal framework for student engagement, and maximize communication routes between students with peers and faculty. Tips are for specific areas of active student engagement, covering curriculum design and development, peer teaching, governance processes, research activities, peer support programs, and interaction with the local community.
    Matched MeSH terms: Universities
  20. Multicentre evaluations of two new rapid IgG4 tests (WB rapid and panLF rapid) for detection of lymphatic filariasis
    Noordin R, Itoh M, Kimura E, Abdul Rahman R, Ravindran B, Mahmud R, et al.
    Filaria journal, 2007;6:9.
    PMID: 17961262
    In the global effort to eliminate lymphatic filariasis (LF), rapid field-applicable tests are useful tools that will allow on-site testing to be performed in remote places and the results to be obtained rapidly. Exclusive reliance on the few existing tests may jeopardize the progress of the LF elimination program, thus the introduction of other rapid tests would be useful to address this issue. Two new rapid immunochromatographic IgG4 cassette tests have been produced, namely WB rapid and panLF rapid, for detection of bancroftian filariasis and all three species of lymphatic filaria respectively. WB rapid was developed using BmSXP recombinant antigen, while PanLF rapid was developed using BmR1 and BmSXP recombinant antigens. A total of 165 WB rapid and 276 panLF rapid tests respectively were evaluated at USM and the rest were couriered to another university in Malaysia (98 WB rapid, 129 panLF rapid) and to universities in Indonesia (56 WB rapid, 62 panLF rapid), Japan (152 of each test) and India (18 of each test) where each of the tests underwent independent evaluations in a blinded manner. The average sensitivities of WB rapid and panLF rapid were found to be 97.6% (94%-100%) and 96.5% (94%-100%) respectively; while their average specificities were both 99.6% (99%-100%). Thus this study demonstrated that both the IgG4 rapid tests were highly sensitive and specific, and would be useful additional tests to facilitate the global drive to eliminate this disease.
    Matched MeSH terms: Universities
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