MyMedR

Fulltext Auditory Cinchonism in COVID Era

Saniasiaya J, Kulasegarah J

Ear Nose Throat J, 2020 Nov;99(9):597-598.

PMID: 32744901 DOI: 10.1177/0145561320947255

An Unusual Presentation of Midline Lethal Granuloma

Chin EW, Saniasiaya J, Hitam S, Hassan E, Kah Wai N

Indian J Otolaryngol Head Neck Surg, 2024 Apr;76(2):2137-2140.

PMID: 38566723 DOI: 10.1007/s12070-023-04466-x

Extranodal natural killer T-cell lymphoma, nasal type (ENKTCL), is a rare form of non-Hodgkin lymphoma that is strongly related to Epstein-Barr Virus (EBV) infection and commonly presents as "midline lethal granuloma." Herein, we report a middle-aged lady who presented with a two-week history of fever, sore throat and constitutional symptoms. Intraoral examination revealed a lacerated soft palate with an ulcerated uvula. A diagnosis of ENKTCL was confirmed through deep biopsies under general anaesthesia supplemented with a positive serum EBV genome. Unfortunately, she succumbed due to disease progression with left frontal brain metastasis with concurrent pulmonary tuberculosis before treatment was completed. The recommended treatment is multimodality with L-asparaginase-containing regimes chemotherapy in an advanced stage, relapsed, or refractory ENKTCL for better outcomes. The quantification of circulating plasma EBV deoxyribonucleic acid (DNA) is helpful as the baseline of tumour load and a biomarker for monitoring treatment response and prognostication. We advocate repeated and deeper core tissue biopsies.

Fulltext An Unexpected Midline Neck Swelling in a Young Female

Lee JPH, Saniasiaya J

Oman Med J, 2024 Jan;39(1):e601.

PMID: 38370333 DOI: 10.5001/omj.2024.45

Acute labyrinthitis: a manifestation of COVID-19 in a teenager

Saniasiaya J, Kulasegarah J

BMJ Case Rep, 2023 Dec 28;16(12).

PMID: 38154869 DOI: 10.1136/bcr-2023-258290

Audiovestibular symptoms following COVID-19 have been long acknowledged, especially in adults. However, acute labyrinthitis presenting as an early manifestation of COVID-19 has not been reported in children. We report COVID-19-induced acute labyrinthitis in a teenager. We report on a boy in his early adolescence with a sudden onset of spinning sensation, imbalance and unilateral hearing loss with a positive SARS-CoV-2 test. Vestibular investigations point towards right labyrinthine hypofunction, and an audiometry test revealed right-sided severe hearing loss. Symptoms improved gradually with steroids and vestibular rehabilitation therapy. However, the long-term repercussions of post-COVID-19 acute labyrinthitis are unknown and must be followed up closely. To our knowledge, this is the first reported case of acute labyrinthitis secondary to COVID-19 in paediatrics. Additionally, we conducted a literature search to elucidate the outcome of COVID-19-induced acute vestibular syndrome in children.

A hard left supraclavicular mass in a young boy-is it cancer?

Ramasamy K, Saniasiaya J, Gani NA

Malays Fam Physician, 2020;15(2):53-55.

PMID: 32843947

Fulltext A Throat that Clicks

Ramasamy K, Saniasiaya J

Iran J Otorhinolaryngol, 2021 Jul;33(117):249-251.

PMID: 34395326 DOI: 10.22038/ijorl.2021.51303.2752

Introduction: Clicking larynx syndrome is a rare condition that may be intriguing to the attending clinician. Patients typically present with clicking sensations in the neck, often obvious during head movement or swallowing. Due to the scarce presentation of such cases, clicking larynx syndrome harbors a high propensity to be an overlooked diagnosis, resulting in a clinical stalemate.

Case Report: Herein, we present a case of clicking larynx in a young girl followed by an overview of the latest literature on the aetiology and treatment options. This case aims to reinforce the presence of this entity further and subsequently increase its awareness among clinicians.

Conclusion: Expeditious diagnosis is imperative not just for the eventual treatment but also for timely relief to the anxious patients who would have been perplexed by the strange clicking in the throat.

Fulltext A Rare Manifestation of Cervical Yolk Sac Tumor in an Unfortunate Infant

Saniasiaya J, Hamid SSA, Mohamad H, Wahab WNNWA, Zawawi N

Turk Arch Otorhinolaryngol, 2019 Sep;57(3):157-160.

PMID: 31620699 DOI: 10.5152/tao.2019.3900

Paediatric germ cell tumor is composed of various neoplasms which exhibit capricious clinical presentation and histological features depending on the age and the area of presentation. Yolk sac tumor is an extremely rare malignant tumor of embryonic origin which usually arises from the gonads. Its manifestation in the head and neck region is extremely rare. Here, we report a rare case of the malignant transformation of mature teratoma into yolk sac tumor of the neck in an infant. Diagnosis was confirmed following histopathological examination of the neck mass along with marked increase of the serum alpha-fetoprotein. The child unfortunately succumbed prior to chemotherapy. We highlight the challenge we faced in diagnosing and managing this rare entity. We would also like to recommend serial monitoring of serum alpha-fetoprotein in all patients with mature teratoma to detect malignant transformation early.

Fulltext A Rare Differential Diagnosis of a Solitary Anterior Neck Mass

Saniasiaya J, Mohamad I

Oman Med J, 2016 Sep;31(5):384-6.

PMID: 27602195 DOI: 10.5001/omj.2016.76

Patients with anterior neck masses commonly present to otorhinolaryngology clinics, but there are limited differential diagnoses for such lesions. Common ones include thyroid nodule and thyroglossal duct cyst. In an elderly patient, a differentiated thyroid carcinoma should be suspected especially if it moves with swallowing. We encountered a typical presentation of a solitary thyroid nodule-like mass with the exception of pulsation in a 65-year-old female. Further investigation, using neck ultrasonography, revealed that it was a variant of right common carotid artery arising from the left common carotid artery. Knowledge of such variants is of great importance as ignorance of such a variation may lead to inadvertent surgical complications during procedures.

A Rare Cause of Dysphonia

Saniasiaya J

Oman Med J, 2021 May;36(3):e274.

PMID: 34164160 DOI: 10.5001/omj.2021.52

'Trachealised oesophagus' feature of late onset atopic march

Saniasiaya J

Postgrad Med J, 2020 12;96(1142):793.

PMID: 32376775 DOI: 10.1136/postgradmedj-2020-137856

Displaying publications 61 - 70 of 70 in total