Displaying publications 781 - 800 of 1035 in total

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  1. Fulltext State of rare disease management in Southeast Asia
    Shafie AA, Chaiyakunapruk N, Supian A, Lim J, Zafra M, Hassali MA
    Orphanet J Rare Dis, 2016 08 02;11(1):107.
    PMID: 27484654 DOI: 10.1186/s13023-016-0460-9
    BACKGROUND: Rare diseases, also referred to as orphan diseases, are characterised by their low prevalence with majority of them are chronically debilitating and life threatening. Given the low prevalence and the widely dispersed but very small patient base for each disease, there may often be a disproportion in the availability of treatments and resources to manage patients, spur research and train experts. This is especially true in Southeast Asian countries that are currently in the process of implementing or revising their universal health coverage schemes. This paper aims to examine the status of rare disease management in Southeast Asian countries. It will serve as the basis for a more active discussion on how countries in the region can address an under-recognised rare disease burden and enhance national and regional capacities.

    METHODS: The study consists of literature reviews and key stakeholders interviews in six focus countries, including the Philippines, Singapore, Malaysia, Indonesia, Vietnam, and Thailand and five countries as best practice, comprising of France, Canada, Australia, Taiwan, and South Korea. Rare disease management initiatives across each country were examined based on the World Health Organization's framework for action in strengthening health systems.

    RESULTS: The results suggest rare disease management remains challenging across Southeast Asia, as many of the focus countries face fundamental issues from basic healthcare systems to funding. Nonetheless, there are substantial improvement opportunities, including leveraging best practices from around the world and organising a multi-stakeholder and regional approach and strategy.

    CONCLUSIONS: Southeast Asian countries have made significant progress in the management of rare disease, but there remain key areas for substantial development opportunities.

    Matched MeSH terms: Indonesia
  2. Fulltext Rapid conversions and avoided deforestation: examining four decades of industrial plantation expansion in Borneo
    Gaveau DL, Sheil D, Husnayaen, Salim MA, Arjasakusuma S, Ancrenaz M, et al.
    Sci Rep, 2016 Sep 08;6:32017.
    PMID: 27605501 DOI: 10.1038/srep32017
    New plantations can either cause deforestation by replacing natural forests or avoid this by using previously cleared areas. The extent of these two situations is contested in tropical biodiversity hotspots where objective data are limited. Here, we explore delays between deforestation and the establishment of industrial tree plantations on Borneo using satellite imagery. Between 1973 and 2015 an estimated 18.7 Mha of Borneo's old-growth forest were cleared (14.4 Mha and 4.2 Mha in Indonesian and Malaysian Borneo). Industrial plantations expanded by 9.1 Mha (7.8 Mha oil-palm; 1.3 Mha pulpwood). Approximately 7.0 Mha of the total plantation area in 2015 (9.2 Mha) were old-growth forest in 1973, of which 4.5-4.8 Mha (24-26% of Borneo-wide deforestation) were planted within five years of forest clearance (3.7-3.9 Mha oil-palm; 0.8-0.9 Mha pulpwood). This rapid within-five-year conversion has been greater in Malaysia than in Indonesia (57-60% versus 15-16%). In Indonesia, a higher proportion of oil-palm plantations was developed on already cleared degraded lands (a legacy of recurrent forest fires). However, rapid conversion of Indonesian forests to industrial plantations has increased steeply since 2005. We conclude that plantation industries have been the principle driver of deforestation in Malaysian Borneo over the last four decades. In contrast, their role in deforestation in Indonesian Borneo was less marked, but has been growing recently. We note caveats in interpreting these results and highlight the need for greater accountability in plantation development.
    Matched MeSH terms: Indonesia
  3. Revision of the genus Coeligetes from Malaysia and Indonesia, and description of Coeligetoides gen. nov. (Coleoptera: Chrysomelidae: Galerucinae)
    Bezděk J
    Zootaxa, 2016 Mar 04;4085(4):504-24.
    PMID: 27394316 DOI: 10.11646/zootaxa.4085.4.3
    The species of the genus Coeligetes Jacoby, 1884 distributed in Malaysia and Indonesia are revised, illustrated and keyed. New species, C. howardi sp. nov. from Borneo is described. New synonymy Coeligetes submetallica Jacoby, 1884 = C. wilcoxi Mohamedsaid, 1994 (syn. nov.) is proposed. New genus and species Coeligetoides trifurcatus gen. nov., sp. nov. (Malaysia, Brunei, Indonesia and Thailand) is described, illustrated and compared with related genera.
    Matched MeSH terms: Indonesia
  4. Parathelphusa pardus, a new species of lowland freshwater crab from swamps in central Sumatra, Indonesia (Crustacea: Brachyura: Gecarcinucidae)
    Ng PK, Riady R, Windarti W
    Zootaxa, 2016 Feb 29;4084(4):495-506.
    PMID: 27394277 DOI: 10.11646/zootaxa.4084.4.2
    A new species of gecarcinucid freshwater crab of the genus Parathelphusa H. Milne Edwards, 1853, is described from freshwater swamp habitats in Pekanbaru, Riau Province, in central-eastern Sumatra, Indonesia. Parathelphusa pardus sp. nov., has a very distinctive colour pattern, and in this respect, resembles P. maindroni (Rathbun, 1902) from Sumatra and Peninsular Malaysia; P. batamensis Ng, 1992, from Batam Island, Indonesia; P. reticulata Ng, 1990, from Singapore; and P. oxygona Nobili, 1901, from western Sarawak. It can be distinguished from these species and congeners by a suite of carapace, ambulatory leg, thoracic sternal and most importantly, male first gonopod characters.
    Matched MeSH terms: Indonesia
  5. Fulltext Treatment of Seborrhoeic Dermatitis in Asia: A Consensus Guide
    Cheong WK, Yeung CK, Torsekar RG, Suh DH, Ungpakorn R, Widaty S, et al.
    Skin Appendage Disord, 2016 May;1(4):187-96.
    PMID: 27386464 DOI: 10.1159/000444682
    Seborrhoeic dermatitis (SD) is common in Asia. Its prevalence is estimated to be 1-5% in adults. However, larger population-based studies into the epidemiology of SD in Asia are lacking, and the aetiology of SD may differ widely from Western countries and in different parts of Asia. In addition, clinically significant differences between Asian and Caucasian skin have been reported. There is a need to define standardized clinical diagnostic criteria and/or a grading system to help determine appropriate treatments for SD within Asia. With this in mind, experts from India, South Korea, Taiwan, Malaysia, Vietnam, Singapore, Thailand, the Philippines, Indonesia, and Italy convened to define the landscape of SD in Asia at a meeting held in Singapore. The consensus group developed a comprehensive algorithm to aid clinicians to recommend appropriate treatment of SD in both adults and children. In most cases, satisfactory therapeutic results can be accomplished with topical antifungal agents or topical corticosteroids. Non-steroidal anti-inflammatory agents with antifungal properties have been shown to be a viable option for both acute and maintenance therapy.
    Matched MeSH terms: Indonesia
  6. Epidemiology and control of schistosomiasis in Southeast Asia
    Harinasuta C
    Southeast Asian J Trop Med Public Health, 1984 Dec;15(4):431-8.
    PMID: 6535256
    Schistosomiasis in Southeast Asia, caused by Schistosoma japonicum, Schistosoma mekongi and Schistosoma japonicum-like, have been reported from six different countries. The S. japonicum infections are highly prevalent in the Philippines with Oncomelania hupensis quadrasi as the vector snail, and in localized areas in Indonesia with O.h. lindoensis as the snail vector. The S. mekongi infections are recent discovery in the Lower Mekong Basin in Laos and Kampuchea, with Tricula aperta as the vector snail. The S. japonicum-like infections are found as isolated cases diagnosed by the finding of S. japonicum-like eggs in the faeces, rectal biopsy, tissue biopsy or at necropsy in Thailand and Malaysia. The control measures of schistosomiasis have been implemented in the Philippines and Indonesia, while further research studies are being conducted in Thailand and Malaysia.
    Matched MeSH terms: Indonesia
  7. Chloroquine resistant Plasmodium falciparum infection from Lampung and South Sumatra, Indonesia
    Pribadi W, Dakung LS, Gandahusada S, Daldyono
    Southeast Asian J Trop Med Public Health, 1981 Mar;12(1):69-73.
    PMID: 7020096
    A report was made of 4 cases of chloroquine resistant Plasmodium falciparum infections. The infections, detected in Jakarta, were imported from Kotabumi, Tanjung Karang, the Island of Pidada in the Lampung Province and from Pangkalpinang on the Island Bangka in the Province of South Sumatra. Treatment with courses of 1500 mg chloroquine base and with increased dosages up to 2250 mg base failed to cure the patients. The chloroquine sensitivity test in vitro was carried out in 3 patients, which showed that the Plasmodium falciparum strains were resistant to chloroquine at the R I level. The strains appeared to be similar to the Malaya Camp strain. In vivo observations revealed that the parasites were resistant at the R I level with a delayed recrudescence. The chloroquine resistant falciparum malaria cases, acquired in South Sumatra, may therefore be regarded as the first reported cases from a focus outside the already known two foci in Indonesia, namely East Kalimantan and Irian Jaya. It may be expected that chloroquine resistant Plasmodium falciparum will be encountered in other parts of Indonesia in the near future. The use of a combination of sulfadoxine and pyrimethamine should not be recommended in Indonesia because chloroquine is still considered the drug of choice against all malaria infections in Indonesia.
    Matched MeSH terms: Indonesia
  8. Early results reported from 1980 round of censuses
    East-West Center. Population Institute
    Asian Pac Cens Forum, 1981 Feb;7(3):1-4, 10.
    PMID: 12310317
    Matched MeSH terms: Indonesia
  9. Individual-level fertility measures derived from the own children method: an evaluation of Southeast Asian census data
    Guest P
    Majalah Demografi Indones, 1991 Jun;18(35):43-58.
    PMID: 12317016
    Matched MeSH terms: Indonesia
  10. Genetic polymorphism of the vitamin D-binding protein (DBP) in crab-eating macaques (Macaca fascicularis)
    Tanaka H, Kawamoto Y, Terao K
    J Med Primatol, 1991 May;20(3):126-32.
    PMID: 1895332
    Vitamin D-binding protein (DBP) of crab-eating macaques (Macaca fascicularis) was examined by means of three electrophoretic methods. DBP phenotypes were observed to be one or two bands in each method. All of DBP molecular variants could be detected by the simultaneous typing with these three methods. Family analysis suggested that DBP variants followed the mode of autosomal codominant inheritance. A total of 17 phenotypes governed by at least 11 alleles were observed in the populations of Malaysia, Indonesia, and the Philippines. The genetic variability was high in Malaysian and Indonesian populations but low in the Philippine population.
    Matched MeSH terms: Indonesia
  11. Female first marriage in East and Southeast Asia: a Kiefer-Neumann model
    Montgomery MR, Sulak DB
    J Dev Econ, 1989 Apr;30(2):225-40.
    PMID: 12342575
    Many studies have shown that schooling levels of husband and wife are important determinants of household behavior in developing countries. This article asks how the schooling levels of husband and wife come to be associated with each other through the marriage market. The Kiefer-Neumann model of labor market search is adapted to marital search, the aim being to explain both the positive sorting on educational levels for spouses, and the positive relationship between female schooling and age at 1st marriage. World Fertility Survey data for Indonesia, Korea, and Malaysia are employed in the analyses.
    Matched MeSH terms: Indonesia
  12. Internal migration and development transitions in South East Asia
    Pryor RJ
    Popul Geogr, 1981 Jul-Dec;3(1-2):57-68.
    PMID: 12179069
    Matched MeSH terms: Indonesia
  13. Demographic development in ASEAN: a comparative overview
    Herrin AN, Pardoko H, Lim LL, Hongladorom C
    Philipp Rev Econ Bus, 1981 Sep-Dec;18(3-4):132-53.
    PMID: 12178278
    Matched MeSH terms: Indonesia
  14. Transferrin C subtyping in Malaysians and in Indonesians from North Sumatra
    Tan SG, Gan YY, Asuan K
    Hum Genet, 1982;60(4):369-70.
    PMID: 7106773
    Malays, Chinese, and Indians from Peninsular Malaysia; Ibans and Bidayuh from Sarawak State; Kadazans from Sabah State, Northern Borneo; and Bataks, Minangkabau, and Javanese from North Sumatra, Indonesia, were subtyped for transferrin C by polyacrylamide gel isoelectric focusing. All nine populations studied are polymorphic for two alleles, TfCl and TfC2, TfC3 was polymorphic in six populations and present as a rare variant in the other three. The frequency of TfC1 ranged from 0.855 in Bidayuh to 0.711 in Javanese, that of TfC2 from 0.231 in Indians to 0.113 in Bidayuh, and that of TfC3 from 0.030 in Javanese and Chinese to 0.008 in Bidayuh. TfDchi is polymorphic in all the populations that we studied except in Minangkabau, in whom it is present as a rare variant, and in Indians, in whom it is absent.
    Matched MeSH terms: Indonesia
  15. Natural virus infections in cynomolgus monkeys
    Suzuki M
    Jpn. J. Med. Sci. Biol., 1981 Aug;34(4):261-3.
    PMID: 7321300
    Matched MeSH terms: Indonesia
  16. Planned population redistribution: lessons from Indonesia and Malaysia
    Laquian AA
    Habitat Int, 1982;6(1-2):39-52.
    PMID: 12279451
    Matched MeSH terms: Indonesia
  17. Health status and the development of health services in colonial state: the case of British Malaya
    Leng CH
    Int J Health Serv, 1982;12(3):397-417.
    PMID: 7118330
    The health of a population and the development of health services in a country at a particular time in history are directly linked to the socioeconomic system. This paper discusses health and health services in Malay Peninsula during the time that it was a British colony. Economic production under British colonialism, which is basically a capitalist system, is organized primarily for the purpose of realizing profits. The health of the population is in direct conflict with and generally subordinated to this main objective. The pattern of health that emerges reflects this general framework. Moreover, health services under the colonialist system are developed primarily to serve the economic interests of the colonialists. Hence, the structure of health services is biased toward curative medicine and centered mainly in the urban areas.
    Matched MeSH terms: Indonesia
  18. Asian-Pacific round of WFS activities
    Asian Pac Popul Programme News, 1979;8(1):16.
    PMID: 12309486
    Matched MeSH terms: Indonesia
  19. Triatomines as experimental vectors of trypanosomes of Asian monkeys
    Weinman D, Wallis RC, Cheong WH, Mahadevan S
    Am J Trop Med Hyg, 1978 Mar;27(2 Pt 1):232-7.
    PMID: 417639
    Systematic surveys of the wild macaques of South Asia by blood culture resulted in the discovery that trypanosomiasis is enzootic in the simians of Indonesia, Malaysia, India, and Thailand. The isolates obtained differ in morphology, metabolism, and ability to multiply in arthropods. Following this discovery, interest focused on possible transmissions of these trypanosomiases. Laboratory-reared and wild-caught insects were studied to determine which are satisfactory intermediate hosts and potential natural vectors. Successful results were obtained with insectary-reared reduviids and Indonesian isolates. In Rhodnius prolixus and Triatoma rubrofasciata the Indonesian trypanosomes multiply for periods which can exceed 40 days. The flagellate infections are in the digestive tract, whereas trypanosomes have never been seen in the salivary glands or in the hemolymph. The feces of trypanosome-carrying reduviids are infective, suggesting a stercoreal method of infection of mammals, and infection was produced in experiments in which feeding by the insects was not possible. The relevance of these findings to natural transmission in Indonesia is not known. Experiments with insects and all other trypanosomal isolates have been negative. The natural transmission mechanism(s) of the simian trypanosomiases in South Asia remains an unsolved problem.
    Matched MeSH terms: Indonesia
  20. Latah: the symbolism of a putative mental disorder
    Kenny MG
    Cult Med Psychiatry, 1978 Sep;2(3):209-31.
    PMID: 710172
    This paper examines the symbolic properties and cultural relevance of latah, a behavioral state noted in Malay and Indonesia since the 19th Century. Most interpretations of latah have been psychological, latah being perceived as a 'mental disorder.' In the following, it is concluded that latah is intimately related to other aspects of Malayo-Indonesian culture and that it is a well-known cultural pattern and not a mental disorder as such, though it may occur among persons, largely women, in a socially and psychologically marginal situation. Latah is a symbolic representation of marginality, and it is as appropriate to certain mythological and religious figures to the socially marginal.
    Matched MeSH terms: Indonesia
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