Mental health is an integral component to the formation of human capital performance. Human capital with high productivity is the key factor to the growth of a country. Thus, this study aims to investigate the relationship between the level of mental health of undergraduate students in Universiti Utara Malaysia (UUM) with their performance. Mental health was measured using the General Health Questionnaire 12-item (GHQ-12) and the performance was based on the Cumulative Grade Point Average (CGPA). A total of 316 undergraduate students at UUM had answered questionnaires that were distributed. The data were analysed descriptively and the effect of the level of mental health on performance was tested using probit model. Based on GHQ-12, 48% respondents were found to have a good mental health status. A total of 67.21% of the students who obtain CGPA 3.67 and above have a good level of health compared with only 36.08% for those with CGPA under 3.67. Based on the probit model, the level of mental health was found to be significant at 1% level in influencing the CGPA. These findings provide indication to policy makers of the importance of mental health in influencing the students’ performance. Mental health education programs should be implemented or enhanced to raise awareness of the importance of good mental health state among students in higher education institution.
Keywords: CGPA; GHQ-12; mental health; productivity; Kedah; Malaysia
Kepercayaan ibu terhadap mitos atau tanggapan salah tentang penyusuan susu ibu didapati mempengaruhi penerimaan mereka untuk menyusui bayi mereka secara eksklusif. Justeru itu, kajian ini dijalankan untuk membentuk satu bahan pendidikan dalam bentuk risalah yang bertajuk “Panduan penyusuan susu ibu: Fakta vs mitos”. Kajian ini melibatkan tiga fasa; fasa I ialah tinjauan dan penilaian keperluan penyusuan susu ibu; fasa II ialah pembentukan bahan pendidikan bercetak dan fasa III ialah evaluasi proses bahan pendidikan bahan bercetak terhadap 41 orang ibu mengandung yang berbangsa Melayu. Seramai 41 orang subjek terlibat dalam fasa III melalui pengiraan saiz sampel kajian dengan program G*Power digunakan dan power kajian ialah 0.8. Dalam fasa III, borang soal selidik pengetahuan pra ujian telah diberikan kepada subjek untuk menilai tahap pengetahuan mereka mengenai penyusuan susu ibu dan borang tersebut dikumpulkan dengan serta-merta selepas dilengkapi. Subjek tersebut diberi masa seminggu untuk membaca dan memahami risalah yang disediakan dan seterusnya menjawab borang soal selidik pengetahuan pos ujian beserta dengan borang penilaian risalah. Dalam fasa III, kajian mendapati kesemua subjek (100.0%) memahami isi kandungan risalah. Manakala 95.1% (n = 39) subjek berpendapat gambar adalah penting untuk menjadikan bahan pendidikan bercetak lebih menarik dan sebanyak 75.6% (n = 31) subjek menyatakan bahawa gambar yang disertakan dalam risalah yang diberi adalah menarik. Majoriti subjek (97.0%) mempunyai keinginan untuk menyusui bayi mereka secara eksklusif selepas membaca risalah yang diberi. Didapati bahawa min peratus skor pengetahuan subjek kajian meningkat secara signifikan (p < 0.001) daripada 83.1 ± 13.1% semasa pra ujian kepada 94.3 ± 6.7% semasa pos ujian dengan t=5.58 dan saiz kesan yang besar, d = 1.13. Secara kesimpulannya, keputusan menunjukkan bahan pendidikan bercetak yang telah dibentuk mendapat respon penilaian positif dan berkesan dalam meningkatkan tahap pengetahuan ibu mengandung mengenai penyusuan susu ibu. Sehubungan dengan ini, risalah yang dibentuk boleh digunakan sebagai alat pengajaran semasa mendidik ibu mengandung mengenai penyusuan susu ibu.
Prevalens obesiti di Malaysia telah meningkat dengan mendadak sejak dua dekad yang lalu. Oleh itu, usaha untuk menangani masalah ini menjadi semakin penting. Objektif umum kajian hirisan lintang ini adalah untuk menilai keberkesanan projek obesiti yang dijalankan oleh NGOs yang dibiayai oleh Lembaga Promosi Kesihatan Malaysia. Dalam kajian ini, data sekunder dari laporan akhir 22 buah projek obesiti telah dianalisiskan untuk menilai keberkesanannya. Maklumat dalam laporan akhir projek telah dimasukkan ke dalam borang penilaian formatif yang disediakan oleh pihak LPKM. Keberkesanan projek ditentukan melalui tahap pencapaian indikator RE-AIM dengan menggunakan 21 indikator berasaskan Model RE-AIM yang telah disahkan. Projek yang mencapaikan 15 hingga 21 indikator dikirakan mempunyai kualiti tinggi, 8 hingga 14 indikator dikirakan kualiti sederhana dan 0 hingga 7 indikator dikategorikan sebagai kualiti rendah. Dengan menggunakan ujian Cohen’s Kappa untuk menilai reliabiliti antara penyelidik terhadap 21 indikator RE-AIM, didapati bahawa terdapat persetujuan yang tinggi antara 2 penyelidik (k = 0.868). Daripada 22 buah projek obesiti yang dikaji, tiada projek yang mempunyai kualiti tinggi, 21 projek didapati mempunyai kualiti yang sederhana dan 1 projek mempunyai kualiti yang rendah. Tiada perbezaan yang signifikan terhadap peratusan pencapaian indikator RE-AIM antara tempoh projek menurut ujian T tidak berpasangan (P > 0.05). Berdasarkan kepada saringan kesihatan yang dijalankan terhadap 1982 orang peserta, 333 (16.8%) orang didapati mempunyai masalah berlebihan berat badan dan 354 (17.9%) orang adalah obes. Kesimpulannya, majoriti projek telah dilaksanakan dengan berjaya. Namun, kajian lanjut disarankan untuk memantau perubahan gaya hidup yang mungkin dapat mengurangkan prevalens obesiti di komuniti di mana projek telah dijalankan.
Media pendidikan bercetak merupakan saluran komunikasi yang utama dalam pendidikan kesihatan awam. Namun, kajian tempatan yang menilai penerimaan media pendidikan bercetak masih terhad di Malaysia. Maka, kajian ini dilakukan untuk menilai media pendidikan bercetak sedia ada yang mensasarkan obesiti di kalangan kanak-kanak untuk kegunaan dalam program pendidikan atau promosi pemakanan. Kajian ini melibatkan dua peringkat. Peringkat pertama merupakan tinjauan keperluan iaitu tinjauan terhadap media pendidikan bercetak sedia ada yang mensasarkan kanak kanak yang mengalami masalah berlebihan berat badan dan obes dan kajian rintis terhadap borang soal selidik yang dibentuk. Manakala peringkat kedua adalah penilaian penerimaan subjek kajian terhadap media pendidikan bercetak dan perubahan tahap pengetahuan mereka selepas membaca media pendidikan bercetak yang diberikan. Skala Likertn digunakan dalam penilaian ini iaitu daripada 1 (sangat tidak memuaskan) hingga 5 (sangat memuaskan). Jumlah subjek dalam kajian ini adalah seramai 67 orang yang terdiri daripada golongan profesional dalam bidang pendidikan dan kesihatan (n = 7), subjek dewasa (n = 30) dan subjek kanak-kanak (n = 30). Di dalam kajian ini, subjek dewasa diberi satu buku kecil yang mengandungi maklumat berkenaan pencegahan dan pengurusan masalah obesiti di kalangan kanak-kanak seperti komplikasi masalah obesiti dan penyediaan makanan. Subjek kanak-kanak pula menerima satu buku kecil yang mengandungi maklumat berkenaan piramid makanan, kepentingan sarapan, aktiviti fi zikal dan sebagainya di samping satu poster yang mengandungi maklumat berkenaan pemilihan makanan sihat. Manakala golongan profesional menerima semua media pendidikan bercetak ini. Kajian ini mendapati penerimaan subjek terhadap isi kandungan, gambar, jadual dan rajah, warna, susun atur gambar, susun atur kandungan, bahasa dan saiz huruf bagi ketiga-tiga media pendidikan bercetak adalah pelbagai, iaitu daripada sangat tidak memuaskan hingga sangat memuaskan. Min skor penilaian keseluruhan terhadap buku kecil yang mensasarkan populasi dewasa adalah 3.9 ± 0.5 manakala min skor penilaian keseluruhan terhadap buku kecil yang mensasarkan populasi kanak-kanak adalah 4.3 ± 0.4 dan poster adalah 3.9 ± 0.9. Skor pengetahuan pemakanan golongan profesional meningkat dari 88.6 ± 11.2% kepada 95.5 ± 3.2% selepas membaca media tersebut. Skor pengetahuan pemakanan subjek dewasa juga meningkat secara signifi kan (p < 0.001)daripada 67.7 ± 13.6% kepada 84.8 ± 15.9%; bagi subjek kanak-kanak, skor pengetahuan pemakanan juga meningkat secara signifi kan (p < 0.001) daripada 65.3 ± 14.4% kepada 84.0 ± 11.4%. Kesimpulannya, media pendidikan bercetak sedia ada mendapat penerimaan yang baik dan dapat meningkatkan tahap pengetahuan kumpulan sasaran. Oleh itu, media pendidikan bercetak tersebut sesuai digunakan dalam mana-mana program pendidikan pemakanan yang berkaitan dengan obesiti kanak-kanak.
Thyroid and gonads are radiosensitive organs which requires radiation shield to reduce the dose received. However,
radiation shielding is not widely used in radionuclide imaging because it is heavy, uncomfortable and can cause pain
in the spine. Therefore, a research was carried out to determine the ability of thyroid and gonad radiation shield
which is thinner and lighter in reducing radiation dose. A study was conducted in Hospital Putrajaya to determine
the radiation dose received by the thyroid and gonads during a complete Positron Emission Tomography-Computed
Tomography (PET-CT) procedure with and without radiation shield. A total of six male staffs have been chosen as subject
and data from 33 complete PET-CT procedures have been collected. For every PET-CT procedure, the subject’s thyroid
and gonad were shielded using 0.5-mm thick radiation shielded, model Mavig 615 (USA) and Shielding International
(USA) respectively. Thermal luminescent dosimeter (TLD) chips were used as radiation dose detector. The average 18FFDG radioactivity administered to the patient was 387 MBq and the average scan time is 9.224 ± 1.797 minutes. The
results showed that the mean equivalent dose received by the thyroid with and without shielding were 0.080 ± 0.033
mSv and 0.078 ± 0.039 mSv respectively. The mean equivalent dose received by gonad with and without shielding
were 0.059 ± 0.040 mSv and 0.061 ± 0.030 mSv respectively. Radiation shield with 0.5 mm thickness is unable to
reduce radiation dose received by the thyroid (p = 0.76) and gonads (p = 0.79) because it is too thin to resist the
high-energy radiation during PET-CT procedures. Thyroid receive higher radiation dose of 0.016 m Sv compared to
the gonads (p < 0.05) because the thyroid’s position is more exposed to radiation sources which are 18F-FDG during
radiopharmaceutical preparation and patients after administered with 18F-FDG during PET-CT procedure.
Keywords: equivalent dose, radiation shield, TLD
Exclusive breastfeeding (EBF) is very crucial for the health of infant as well as mother. However, the prevalence of
exclusive breastfeeding is very low especially among working mother. Since the prevalence of EBF might be influenced by
the level of knowledge on EBF, researcher comes to critical thinking to conduct this study to evaluate level of knowledge
on EBF among working mother. A cross sectional design study was carried out to determine knowledge level on exclusive
breastfeeding among working mother, and its relationship with demographic data in Hospital Canselor Tuanku Muhriz
(HCTM). A total 283 respondents were recruited to participate in this study. The respondents’ knowledge level on exclusive
breastfeeding was identified using Kim & Chapman (2013) Questionnaire on Knowledge and Practice about Exclusive
Breastfeeding. The result showed that majority of the respondents (56.9%) had high knowledge on exclusive breastfeeding.
For demographic data, factors such as age, level of education, and family income had shown a significant association (p
< 0.05) with level of knowledge on exclusive breastfeeding. In conclusion, the level of knowledge of EBF was identified
among working mother, yet it has been influenced by mother’s sociodemographic background
Recognising the epidemic of overweight and obesity among Malaysians, formulation of intervention programmes such as
a weight management programme at workplace is essential. This study aimed to determine the effectiveness of a structured
weight management programme at workplace among overweight and obese employees. In this quasi-experimental
study, sixty-four of overweight and obese adults were recruited and divided into two groups (intervention group,
n = 32 and control group, n = 32). Subjects in the intervention group received three months scheduled programme and the
control group received a routine weight management consultation from dietitians. Significant group effect was found on
waist circumference (WC) in men (p < 0.05) and Body Mass Index (BMI) in women (p < 0.05). Men from the intervention
group had reduced their WC by 3.4% (-3.7 cm) as compared to controls of 0.7% (-0.8 cm). Women in the intervention
group improved their BMI by 1.4% (-0.4 kg/m2
) as compared to controls at 0.3% (-0.1 kg/m2
). Total cholesterol and LDL-C
reduced among women in both intervention and control group with significant time effect (p < 0.05). As a conclusion a
structured weight management programme effectively improved WC in men and BMI in women, and appeared to be as
effective as individual diet counselling by dietitians in improving lipid profiles in women.
The objective of this study was to determine the Immunoglobulin E-binding proteins (IgE) and major allergens of Scomberomorus commerson Lacepede (Narrow-barred Spanish mackerel). Allergen extracts were obtained from uncooked and cooked fish by homogenization in phosphate-buffered saline followed by continuous extraction at 4oC or on ice. Protein profiles and IgEbinding patterns were then detected by means of sodium dodecyl polyacrylamide gel electrophoresis (SDS PAGE) and immunoblotting using sera from patients sensitized to the fish. SDS-PAGE of the uncooked fish extracts revealed 26 protein bands in the range of about 11 to >175 kD, while the cooked extracts produced fewer protein bands. Immunoblotting demonstrated 17 IgE-binding bands, ranging in molecular weight from 11 to 151 kD. Two components with molecular weight of about ~50 and 42 kD showed the highest frequency of IgE-binding (62.2 and 51.4% respectively) and were identified as the major allergens of this fish allergy. Other IgE-binding proteins including a protein at ~12 kD which was equivalent in size to parvalbumin were identified as the minor allergens.
Kimura's disease is a chronic inflammatory disorder which affects the subcutaneous tissues of the head and neck, axilla and upper limb as well as the groin region. In the head and neck region, major salivary glands and regional lymph nodes are mainly involved with associated eosinophilia and an elevated IgE concentration. Three cases of Kimura's disease involving the parotid glands, lymph nodes and cheek are presented with a brief review of the literature.
Walking 10,000 steps daily is associated with beneficial health outcomes. Recent systematic reviews have suggested that pedometers may be an effective motivational tool to promote walking. The aim of this study was to study the effectiveness of a 10-week, pedometer-based walking intervention to improve physical activity, body composition and metabolic health indices in a sample of suburban community-dwelling adults not meeting current physical activity recommendations. After screening, 34 overweight/obese individuals (mean age: 46 ± 8 years, mean BMI: 28.3 ± 4.2 kg/m2) were accepted into the walking program conducted by the Health Promotion Community Centre, Bangi. Subjects were instructed to increase their steps by 3000 steps daily above their baseline values for 10 weeks. Daily step count, body weight, BMI, waist circumference, as well as blood pressure, fasting glucose and lipids were evaluated at baseline and following the 10-week intervention. Thirty-one participants completed the program with 100% adherence. The average daily steps recorded during the 10-week intervention was 9693 ± 2196 steps per day. Mean daily steps increased from 8679 ± 2567 steps in Week 1 to 10,766 ± 3200 steps in Week 10 (p = 0.040). Overall, there were reductions in body weight (-1.13%, p = 0.010), waist circumference (-3.5%, p = 0.001) and BMI (-1.41%, p = 0.008) as well as fasting blood glucose (-8.5%, p = 0.003) and systolic blood pressure (-4.8%, p = 0.007) following the intervention. The findings of this study demonstrated that a goal-driven, pedometer-based walking intervention for 10 weeks resulted in a modest reduction in body weight and improved metabolic health outcomes in overweight/obese, community-dwelling adults.
Ujian teks bacaan Bahasa Melayu telah dibangunkan untuk menilai prestasi membaca kanak-kanak sekolah rendah.
Seramai 120 pelajar Tahap 1 (purata umur 8.5 ± 0.5 tahun) dan Tahap 2 (purata umur 10.5 ± 0.5 tahun) berpenglihatan
normal telah dipilih secara rawak. Subjek diminta membaca lima teks bacaan secara rawak dengan kuat. Masa selesai
membaca setiap teks bacaan diukur dan sebarang kesalahan menyebut perkataan direkodkan. Purata kelajuan membaca
dan kadar membaca diukur sebagai perkataan per minit (ppm). Kelajuan membaca Tahap 1 adalah 88.81 ± 1.95 {ralat
piawai (RP)} ppm dan kadar membaca pula adalah 87.20 ± 1.98 (RP) ppm. Bagi Tahap 2, kelajuan membaca adalah
108.12 ± 1.66 (RP) ppm manakala kadar membaca adalah 107.22 ± 1.67 (RP) ppm. Kelajuan dan kadar membaca di
antara subjek bagi setiap teks bacaan menunjukkan tiada perbezaan yang signifi kan (p > 0.05) dengan nilai p bagi
kedua-duanya adalah 0.91 manakala bagi tahap 2 pula nilai p adalah 0.57. Perbandingan di antara teks bacaan juga
menunjukkan tiada perbezaan yang signifi kan (p > 0.05). Semua teks bacaan adalah homogen secara statistik maka teks
bacaan yang dibangunkan boleh dipilih secara rawak semasa ujian dan tidak akan memberi kesan kepada penilaian
prestasi membaca di kalangan kanak-kanak sekolah rendah.
When medical and surgical intervention cannot alleviate all of the impairments resulting from diseases of the eye, visual rehabilitation can help reduce the disability and increase the quality of life. Data from 169 patients seen at the UKM Low Vision Clinic (UKM LVC) over the past 2 years were examined and analysed. The age ranged from 6 to 87 years of age. The main cause of ocular pathological categories was conduction (63.9%), media (24.9%) and congenital (11.2%) related problems. The main causes of low vision at UKM LVC were congenital cataract, retinitis pigmentosa, glaucoma, cataract and diabetic retinopathy. 84% of these patients received low vision devices to improve their near or/and distance vision. The most common optical devices dispensed at UKM LVC were near high addition spectacle, hand magnifiers and stand magnifiers. Medical, vision care and rehabilitation professionals working together can offer a comprehensive treatment plan for the visually impaired, offering these patients the very best services to increase their quality of life.
Fungsi penglihatan dipengaruhi oleh proses penuaan dan tanpa intervensi yang bersesuaian boleh mengakibatkan kemerosotan tahap penglihatan. Keadaan ini jika berterusan akan mengakibatkan kesukaran melakukan aktiviti kehidupan seharian dan memberi kesan kepada kualiti hidup kepada warga emas. Kajian ini mengkaji kesan gangguan penglihatan terhadap aktiviti harian dan kualiti hidup warga emas. Ukuran yang dilakukan ialah tahap penglihatan jauh menggunakan carta LogMAR untuk menilai gangguan penglihatan. Ujian kualiti hidup dilaksanakan menggunakan soalan kualiti hidup penglihatan terhad (LVQOL) dan ujian keupayaan melakukan aktiviti harian menggunakan indeks Barthel (BI). Dapatan kajian menunjukkan bahawa gangguan fungsi penglihatan bertambah teruk dengan peningkatan umur, begitu juga didapati bahawa BI berkurangan apabila fungsi penglihatan merosot. Skor kualiti hidup LVQOL pula berkurangan bersama-sama kemerosotan tahap penglihatan. Tiga puluh lima peratus warga emas dalam kajian ini memerlukan intervensi optometri dan penglihatan terhad, Kesimpulannya, kemerosotan tahap fungsi penglihatan di kalangan warga emas boleh menyebabkan penurunan keupayaan dalam melakukan aktiviti harian. Di samping itu, akuiti visual yang tidak dibetulkan akan menyebabkan penurunan kualiti hidup warga emas.
Kajian rintis telah dilakukan di Kuala Lumpur dalam kalangan 30 orang kanak-kanak berumur 10-18 tahun bagi mengumpulkan pandangan mereka mengenai strategi pemasaran kempen anti-merokok. Hasil kajian menunjukkan kempen tersebut kurang berkesan mencegah kanak-kanak daripada merokok. Faktor-faktor yang menyebabkan kempen ini kurang berjaya mengurangkan tabiat merokok dalam kalangan kanak-kanak adalah kanak-kanak tidak merasa takut dengan poster dan gambar penyakit kritikal yang dipaparkan (60%), mereka dengan mudah boleh mendapatkan rokok (66%), serta kekurangan kerjasama semua sektor masyarakat dalam menyokong kempen ini (77%). Strategi pemasaran kempen anti-merokok dari aspek produk, harga, aksesibiliti, promosi, dasar sosial dan perkongsian komuniti perlu diperbaiki dan diberi penekanan seimbang untuk menjamin keberkesanan kempen secara komprehensif.
Food insecurity is associated with an inadequate nutrient intake among older adults. Therefore, this study aimed
to determine the food intake among older adults with food insecurity in an agricultural settlement, i.e. Felda Land
Development Authority (FELDA) settlers at Lubuk Merbau, Kedah. A total of 70 older adults were selected as a subsample
to record data on food supply for a week, from an original study (n = 289: mean age= 69.2 ± 7.4 years). This study was
conducted through a house to house visit of which respondent was interview to get information on sociodemographic
and food insecurity. Food intake was recorded for a week using food supply questionnaire. Food insecurity was assessed
using Food Security Tool For the Elderly. Results indicated that 19.7% respondents had food insecurity. Energy intake
was found to be higher among women with food insecurity (2329.0 ± 814 kcal/day) compared to respondents with food
secured (1836 ± 447 kcal/day) (p < 0.05). However, after removing over reporters, the energy intake among both groups
did not differ significantly (1890 ± 208 kcal/day and 1643 ± 233 kcal/day). Total intake from food groups of fat, oil, sugar
and salt was higher among respondents with food insecurity (106.6 ± 60.0 g/day) as compared to those who were food
secured (80.3 ± 30.1 g/day)(p < 0.05). In conclusion, food insecurity affected approximately a fifth of the respondents and
associated with unhealthy diet with high in fat, oil, sugar and salt. There is a need to formulate intervention programme
to improve the quality of diet of older adults at high risk of food insecurity.
Hope leads to lower depression and anxiety and is associated with improved quality of life of cancer patients. In this
study, Hope Scale (HS) was translated into Malay, and the psychometric properties of the Malay version of the Hope
Scale were investigated among Malaysian cancer patients. Concurrent translation and back translation of the original
English version of the Hope Scale were performed, and the Malay version was administered to 195 cancer patients
with different cancer diagnoses at baseline assessment and 2 months later at follow-up. The Hope Scale (Malay) total
score (Cronbach’s α = 0.72; intraclass correlation coefficient (ICC) = 0.67) and its domains (Cronbach’s α [pathway] =
0.7; Cronbach’s α [agency] = 0.7; ICC[Pathway] = 0.64; ICC[Agency] = 0.70) demonstrated acceptable internal consistencies and
test-retest reliability. Convergent and discriminant validities were also achieved by the Hope Scale (Malay). The Hope
Scale (Malay) demonstrated construct validity, as confirmatory factor analysis demonstrated that the items in the Hope
Scale (Malay) best fit into two domains, which was true for the original English version. The Hope Scale (Malay) had
acceptable psychometric properties and thus is suitable for assessing hope in Malaysian cancer patients.
Urinary incontinence (UI) is a common disorder among older adults, with a global prevalence between 2% to 58%. UI has been associated with social isolation, increased morbidity and reduced quality of life (QoL). The aim of this study was to investigate the sociodemographic, clinical, cognitive and physical function risk factors of UI among Malaysian community dwelling older adults. This study is part of a larger scale population based longitudinal study on neuroprotective model for healthy longevity among older adults (LRGS TUA). A total of 1560 Malaysian community dwelling older adults aged 60 years and above were screened in this phase III LRGS study. Participants sociodemographic and clinical history were obtained. Mini Mental State Examination (MMSE), Rey Auditory Verbal Learning Test (RAVLT) and Digit Span tested cognitive function. Timed Up and Go Test (TUG), Hand Grip Strength Test, Chair Stand Test and Lawton Instrumental Activities of Daily Living tested physical function. The overall prevalence of UI was 15.7% (n = 245) in this study, with 11.8% (n = 88) in men and 19.3% (n = 157) in women. Logistic regression analysis showed that TUG (Adjusted odds ratio [OR], 1.071; 95% confidence interval [CI], 1.02-1.13), MMSE (OR, 0.93; CI, 0.90-0.97), weight (OR, 1.02; CI, 1.00-1.03), and constipation (OR 0.60; CI, 0.46-0.78) (p < 0.005) were significant risk factors of UI. The results indicate, decreased physical and cognitive function; increase in weight and having constipation increased the risk of UI. Maintaining optimum mobility, cognitive function, body weight and constipation prevention are vital in the prevention and management of UI among older adults.
Older adults who fall recurrently have sub-optimal physical performance especially muscle strength, mobility and balance. Recurrent falls lead to a heightened fear of falls. However, there is limited information regarding other domains of physical performance, namely flexibility and endurance. In addition, there is still limited knowledge pertaining fear of falls and physical activity levels among Malaysian community-dwelling older adults who are recurrent fallers. The aim of our study was to compare fear of falls, physical performance and physical activity levels among older adults with falls and recurrent falls. This cross- sectional study was carried out in two Malaysian urban districts. Physical performance was examined using Functional Fitness MOT (FFMOT). Modified Baecke Questionnaire and Activities-Specific Balance Confidence (ABC-6) Scale were administered to evaluate the level of daily physical activity and fear of falls respectively. A total of 35 older adults participated in this study, 20 fallers (mean age: 71.95±8.22) and 15 recurrent fallers (mean age: 76.73±8.82) respectively. Our study results showed that older adults with recurrent falls had significantly reduced lower extremity strength, dynamic balance, endurance, balance confidence in activities of daily living and physical activity levels compared to faller group (p < 0.05). Although flexibility and upper limb strength were not significantly different among fallers and recurrent fallers, overall improvement in physical performance should be targetted in falls prevention and management. This is vital to prevent further deterioration in physical performance among older adults with recurrent falls.
The fi rst part of this study was about measurement of dosimetric parameters for small photon beams to be used as input
data for treatment planning computer system (TPS) and to verify the dose calculated by TPS in Stereotactic Radiosurgery
(SRS) procedure. The beam data required were percentage depth dose (PDD), off-axis ratio (OAR) and scattering factor.
Small beams of 5 mm to 45 mm diameter from a circular cone collimator in SRS were used for beam data measurements.
Measurements were made using pinpoint ionisation chamber (0.016cc). In the second part of this study, we reported
the important of carrying out quality assurance (QA) procedures before SRS treatment which were found to infl uence the
accuracy of dose delivery. These QA procedures consisted of measurements on the accuracy in target localization and
treatment room laser alignment. The calculated TPS dose for treatment was verifi ed using pinpoint ionisation chamber
and thermoluminescent detector (TLD) 100H. The deviation mean between measured and calculated dose was -3.28%.
The measured dose obtained from pinpoint ionisation chamber is in good agreement with the calculated dose from TPS
with deviation mean of 2.17%. In conclusion, pinpoint ionisation chamber gives a better accuracy in dose calculation
compared to TLD 100H. The results are acceptable as recommended by International Commission on Radiation Units
and Measurements (ICRU) Report No. 50 (1994) that dose delivered to the target volume must be within ± 5% error.
DNA damaging effect of the salted and fermented food products (salted fishes, dried shrimps and shrimp pastes) collected from three different locations in Malacca namely Pantai Puteri, Batang Tiga and Kelemak on the DNA of the Chang liver cells were evaluated via Alkaline Comet Assay. Treatment at 62.5 mg/ml following 24 hours of incubation was used based on the preliminary cytotoxicity data. Percentage of damage to the DNA was calculated using software for scoring based on the tail moment and tail intensity (severity of the DNA damage). Hydrogen peroxide was used as positive control at 0.1 mM following 30 minutes of incubation in 4 C. The results showed that the methanol extracts of shrimp pastes and salted fish from Pantai Puteri, exhibited a higher DNA damage (shrimp pastes - TM - 8.33 ± 2.19; TI - 31.67 ± 5.84, salted fishes - TM - 2.25 ± 0.86; TI - 9.25 ± 1.55) and were expressed as (shrimp pastes) 56.66 ± 8.74% of DNA damage and methanol salted fish extracts from the same location showed 13.00 ± 2.84% of the DNA damage on Chang liver cells compared to the other extracts. Values for methanol extract of shrimp pastes from Pantai Puteri were comparable to the positive control - Hydrogen peroxide (TM- 9.50 ± 1.50; TI - 30.50 ± 2.50). On the other hand, aqueous salted fishes extract from Pantai Puteri (TM - 1.33 ± 0.42; TI - 8.67 ± 2.42) and shrimp pastes extracts from Kelemak (methanol extract - TM -1.75 ± 0.15; TI -7.50 ± 0.50, aqueous extract - TM - 1.00 ± 0.00; TI - 5.00 ± 0.00) showed slightly high value for tail moment and tail intensity as compared to negative control (TM - 0.29 ± 0.05; TI - 2.50 ± 0.29). Values for methanol extracts of shrimp pastes from Pantai Puteri were comparable to the positive control (TM- 9.50 ± 1.50; TI - 30.50 ± 2.50). In conclusion, our results demonstrate genotoxic damage induced by few salted and fermented food extracts in Chang liver cell.