Displaying publications 141 - 160 of 293 in total

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  1. Ibrahim Gambo, Nor Haniza Sarmin, Sanaa Mohamed Saleh Omer
    MATEMATIKA, 2019;35(2):237-247.
    MyJurnal
    In this work, a non-abelian metabelian group is represented by G while represents conjugacy class graph. Conjugacy class graph of a group is that graph associated with the conjugacy classes of the group. Its vertices are the non-central conjugacy classes of the group, and two distinct vertices are joined by an edge if their cardinalities are not coprime. A group is referred to as metabelian if there exits an abelian normal subgroup in which the factor group is also abelian. It has been proven earlier that 25 non-abelian metabelian groups which have order less than 24, which are considered in this work, exist. In this article, the conjugacy class graphs of non-abelian metabelian groups of order less than 24 are determined as well as examples of some finite groups associated to other graphs are given.
    Matched MeSH terms: Head
  2. Aziz, A., Mohamad, I., Zawawi, N.
    Malaysian Family Physician, 2018;13(2):32-35.
    MyJurnal
    Kimura disease presents as benign lesion and is commonly present among the Asian population. It
    is a disease with a favourable prognosis and a peak age of onset in the third decade. It is a chronic
    inflammatory disorder of unknown etiology that involves the lymph nodes and subcutaneous
    tissues of the head and neck region. We report a case of a 15-year-old boy with multiple Kimura
    lymphadenopathies involving the left posterior auricular region as well as the anterior and posterior
    triangles of the neck.
    Matched MeSH terms: Head
  3. Choy, Yew Sing, Sinniah, D.
    MyJurnal
    Reported is the first case of syringomyelia and syringobulbia associated with Arnold Chiari I malformation in a Malaysian child. The initial complaint was that of unilateral anhidrosis of the face. The chief presenting features were dissociated sensory loss, asymmetrical weakness of the left upper limb associated with subluxation of left shoulder and signs of upper motor neurone lesion in the left lower limb. One unusual feature was the presence of vesiculation followed by ulceration of the pinnae of both ears. Magnetic resonance imaging (MRI) of the posterior fossa and cervical and thoracic cord facilitated the diagnosis and was the most useful diagnostic procedure in this child.
    Matched MeSH terms: Head
  4. Mansharan Kaur Chainchel Singh
    MyJurnal
    Solitary fibrous tumours (SFTs) are unusual mesenchymal tumours that were first described as primary spindle-cell neoplasms of the pleura. These tumours have been described in many other locations, including the urogenital system, orbit, mediastinum, and upper respiratory tract. These tumours are generally benign in nature, however some of them can be locally invasive and have the potential to be malignant. Although about 12%-15% of them occur in the head and neck area, SFT of the nasal cavity and paranasal sinuses are extremely rare. We present a case of a solitary fibrous tumour arising from the right maxillary sinus in a 50 year old Chinese man.
    Matched MeSH terms: Head
  5. Cheah Yoke Kqueen, Yaghma Masood, Nurul Syakima Ab Mutalib, Sethu Thakachy Subha, Norhafizah Mohtarrudin
    MyJurnal
    MicroRNAs (miRNAs) are small noncoding RNAs that involved in various normal and cancer-related cellular pro-cesses. Studies on expression profiling of miRNAs have been performed and the data showed that some miRNAs are up-regulated or down-regulated in cancer. miRNAs play a crucial role in HNSCC development, metastasis, prognosis and survival rate. Several studies have been conducted previously to investigate that use of miRNAs as the biomark-ers in disease diagnostic/prognostic and potential therapeutic targets management that may improve the outcomes of HNSCC. Our previous study revealed that upregulation of oncogenic miRNAs including hsa-miR-181a-2*, hsa-miR-29b-1*, hsa-miR-181a, hsa-miR-181b, hsa-miR-744, hsa-miR-1271 and hsa-miR-221* were able to distinguish HNSCC from normal samples. These miRNAs may contribute in a simple profiling strategy to identify individuals at higher risk of developing head and neck cancers, thus helping in the elucidation of the molecular mechanisms involved in head and neck cancer pathogenesis.
    Matched MeSH terms: Head and Neck Neoplasms
  6. Sok Ching Cheong
    MyJurnal
    Head and neck cancers have been reported to have high immune infiltration scores, and clinical benefits of the anti-PD1 checkpoint inhibitor have been demonstrated in recurrent and metastatic cancers. Recent genetic signa-tures of the immune compartment have provided insights to delineate immune-active and -exhausted subtypes, to understand the immune status of OSCC patients that could further drive the development of novel immunotherapies. Vaccination with tumour-associated antigens is an approach to improve tumour recognition which could result in the eradication of cancer cells. Here, I would describe our efforts in developing antigen-specific vaccines for head and neck cancer. Using the B6.Cg-Tg(HLA-A/H2-D)2Enge/J mice bearing established tumours overexpressing the tumour antigens, we demonstrated that the vaccine delayed tumour growth, and in combination with anti-PD1, completely eliminated the tumour. The vaccine increased the expression of PD1 in T cells, and vaccinated animals showed increased antigen-specific responses by the ELISPOT assay. In summary, our data show that antigen-specific vaccine works synergistically with anti-PD1 and could be a promising therapeutic agent for head and neck cancer.
    Matched MeSH terms: Head and Neck Neoplasms
  7. Nur Al - Izzah binti Nazri, Shamsul Bahri Mohd Tamrin, Dayana Hazwani Mohd Suadi Nata, Ng Yee Guan
    MyJurnal
    Introduction: Safety helmets are one of the personal protective equipment (PPE) that to decrease the impact of any falling object to the skull and to avoid head and brain injury by many industries, including palm oil plantation. Nev- ertheless, the level on the usage of the current safety helmet is very low due to a few factors that lead to the discom- fort. Among the common issues for the non-compliance of safety helmets are their discomfort, ventilation, weight and safety. This study aims to determine subjective preference of the new prototypes’ safety helmets device among palm oil plantation harvesters. Methods: A cross-sectional study conducted among 124 harvesters in three palm oil plantations located in Sabah, Malaysia. A set of questionnaires used to collect data on their socio-demographic background, perceptions toward existing safety helmets and their subjective preference of new safety helmets pro- totypes. Apart from that, six harvesters were randomly choosing to attend an interview session for qualitative study. Results: The descriptive analysis indicate that among the emphasized issues regarding non-compliance of existing safety helmet were due to discomfort (66.1%), poor ventilation (97.6%), load of safety helmet (83.3%) and safety issues (68.5%). In terms of new safety helmets prototypes, 72.6% of the harvesters preferred Design C to be worn for work in the plantation. Conclusion: It can be suggested that the existing safety helmet is uncomfortable and was not design ergonomically namely loose size and discomfort. Design C was the most preferred to be worn for work in the palm oil plantation.
    Matched MeSH terms: Head; Head Protective Devices
  8. Wai Heng Chew, Abdul Aziz Marwan, Ummi Nadira Daut, Rosmadi Ismail, Mona Zaria Nasaruddin, Jamalul Azizi Abdul Rahman
    MyJurnal
    Sarcomas usually frequented in the head and neck region of young adults. Trachea is a rare site, and due to scarce clinical data, its clinical outcome is unclear. We reported a case of 60-year old patient presented with progressive worsening shortness of breath, cough, and progressive worsening dysphagia. Computer tomography scan revealed extensive 2 lobulated soft tissue lesions within and surrounding the trachea at the T4 level. Rigid bronchoscopy with mass cryo-debulking was performed and ultimately synovial sarcoma was diagnosed. Shortness of breath was com- pletely relieved post-procedure.
    Matched MeSH terms: Head
  9. Nurzuhairiza Zolkifli, Shamsul Bahri Mohd Tamrin, Ng Yee Guan, Nur Shuhada Mohd Shukoor, Nur Fitriyah Md Akir, Ng Gin Siong, et al.
    MyJurnal
    Safety helmet become vital personal protective equipment especially in the plantation in preventing the head from injury. This study evaluate the knowledge, attitude and practice on safety helmet usage among harvesters, the association between knowledge, attitude and practice of safety helmet usage with head injury; and the significant differences of the safety helmet practices before and after the intervention. A cross-sectional study was conducted among 109 harvesters in two oil palm plantation located in Selangor, Malaysia. A set of questionnaire was used to collect the socio demographic background data, knowledge, attitude and practice on the usage of safety helmet. An intervention program through tool box talk on proper usage of safety helmet also was given followed by an observation to look for the differences before and after the tool box promotion on the use of safety helmet. Result from the descriptive analysis showed high score for knowledge, fair score for the attitude and practice among harvesters. There is no association between knowledge (X2=2.733; p>0.05), attitude (X2=2.546; p>0.05) and practice (X2=2.473; p>0.05) with the head injury. The result also gave no significant differences (p>0.05) of the practices before and after the intervention. However, the trends showed decrease in number of practices after the intervention. This study reveals that the knowledge, attitude and practice are not a prominent indicator for head injury among harvesters.
    Matched MeSH terms: Head; Head Protective Devices
  10. Mohd Syazwan, S., Aqbal, H.A., Azhar, H., Zulhadi, M., Sharifah Allyana, S.M.R., Baba M.D.
    MyJurnal
    Pedestrians' fatality trend in road crashes has been improving in recent years though it remains third in rank behind
    motorcyclists and car occupants. Based on the statistics, young pedestrians were the most affected group and the
    commonest injury regions were head and legs. Pedestrian crashes occurred primarily in rural areas and straight roads
    and at low light environment, and often involve cars and motorcycles. In addition to existing issues of careless and
    illegal crossing practices, there are potential new hazards face by pedestrian, which are mobile electronic device use
    and electric vehicle, especially when crossing roads. Road safety programs and interventions shall consider these new
    issues.
    Matched MeSH terms: Head
  11. Omar R, Knight VF, Aziz Mohammed MA
    Malays Fam Physician, 2014;9(3):27-33.
    PMID: 26425302 MyJurnal
    Work-related ocular injuries and illnesses were among the major causes of job absenteeism. This study was conducted to determine if low vision rehabilitation was provided following work-related ocular problems among industrial workers in a developing country. This was a retrospective analysis of case records.
    Matched MeSH terms: Head
  12. Aziz A, Mohamad I, Zawawi N
    Malays Fam Physician, 2018;13(2):32-35.
    PMID: 30302182
    Kimura disease presents as benign lesion and is commonly present among the Asian population. It is a disease with a favourable prognosis and a peak age of onset in the third decade. It is a chronic inflammatory disorder of unknown etiology that involves the lymph nodes and subcutaneous tissues of the head and neck region. We report a case of a 15-year-old boy with multiple Kimura lymphadenopathies involving the left posterior auricular region as well as the anterior and posterior triangles of the neck.
    Matched MeSH terms: Head
  13. Teh KH, Ruben JK, Chan CK, Abbas AA
    Malays Orthop J, 2020 Jul;14(2):134-137.
    PMID: 32983389 DOI: 10.5704/MOJ.2007.022
    Avascular necrosis and non-union are two most dreaded complications of femoral neck fracture fixations. Hip replacement seems to be a simple solution for this complex problem. However, the long-term efficacy of prosthetic replacement in the young population with higher functional demand is still questionable. Femoral head preserving valgus subtrochanteric osteotomies in properly selected cases have strong support from literature. The conventional technique of valgus subtrochanteric osteotomy involves lateral based wedge resection. Alternatively, a simpler sliding oblique subtrochanteric osteotomy without any wedge removal can also be performed. We hereby describe a successful case of sliding subtrochanteric osteotomy with 135° dynamic hip screw (DHS) plate fixation in treating non-union neck of femur fracture in a young gentleman.
    Matched MeSH terms: Femur Head
  14. Malerba G, Basilico M, Bonfiglio N, Maccauro G
    Malays Orthop J, 2020 Nov;14(3):177-179.
    PMID: 33403082 DOI: 10.5704/MOJ.2011.029
    Isolated apophyseal avulsion of the greater trochanter is a rare condition in the paediatric population, frequently related to avascular necrosis of the femoral head. Since there are few cases in the literature, there is no consensus regarding the best treatment of this injury. Our study describes the case of a 9-year-old patient with an avulsion of the right greater trochanter. A minimally invasive osteosynthesis was performed, achieving complete clinical and radiographic healing of the patient and no long-term complications after four years.
    Matched MeSH terms: Femur Head; Femur Head Necrosis
  15. Kamath SU, Agarwal S, Austine J
    Malays Orthop J, 2020 Nov;14(3):143-150.
    PMID: 33403075 DOI: 10.5704/MOJ.2011.022
    Introduction: With a higher proportion of young individuals undergoing uncemented hip arthroplasty, a close match in the dimension of the proximal femur and the implanted prosthesis is paramount. This is a study to gain insight into geographical variation in proximal femur morphology to determine the reference values to design uncemented femoral stems for a south Indian population, and also the effect of ageing and gender on the proximal femur morphology.

    Materials and Methods: The study comprised of two groups. For the first group, 50 unpaired dry femur bones were obtained from adult human cadavers; and the second group was a clinical group of 50 adult patients. Standardised radiographic techniques were used to measure the extra-cortical and intra-cortical morphometric parameters. Based on these, dimensionless ratios were calculated to express the shape of the proximal femur. The data were expressed in terms of mean and standard deviation and a comparison made with other studies.

    Results: A significant difference was noted across various population subsets within the Indian subcontinent and also in comparison to the Western population, suggestive of regional variation. The measurements made in cadaveric bone differed significantly from those in live patients, especially the femoral head diameter and extra-cortical and intra-cortical width. Femoral offset, head height and diameter were significantly less in females.

    Conclusion: The south Indian population needs customised implants with an increase in neck shaft angle and a decrease in intra-cortical and extra-cortical width for press fit in hip arthroplasty. The variation between the two sexes must also be accounted for during prosthesis design.

    Matched MeSH terms: Femur Head
  16. Jha V, Ahmed T
    Malays Orthop J, 2020 Jul;14(2):72-82.
    PMID: 32983380 DOI: 10.5704/MOJ.2007.015
    Introduction: Proximal femoral nail (PFN) is a commonly used implant for intertrochanteric fractures which is designed according to western femoral measurements. However, anthropometry of proximal femur in Indian and in general, Asian, are smaller. So a modified short PFN with smaller dimensions was developed. This study analyses the radiological and functional outcome of treatment of intertrochanteric fractures with modified short PFN.

    Materials and Methods: A retrospective study analysed 120 adult patients operated between 2014-2017 using modified short PFN for intertrochanteric fractures, having a minimum follow-up of 12 months. Clinical and radiological parameters including tip-apex distance (TAD), position of tip of lag screw in femoral head, lateral slide of lag screw as well as length of anti-rotation screw were measured. Final functional outcome was assessed using Barthel's index and Kyle's criteria.

    Results: Good reduction was achieved in 90.83% cases and 79.16% had ideal placement of lag screw in femoral head. Intra-operative difficulties were encountered in 13.33% (n=16). Mean TAD AP (anteroposterior) was 11.8mm, TAD LAT (lateral) was 11.0mm and mean TAD TOT was 22.8mm. Overall mean lateral slide was 3.20mm and it was more in unstable fracture. We had five mechanical failures, one patient with screw breakage without loss of reduction and two peri-implant fractures after union. 81.66% returned to pre-injury levels of activity with 88.33% good to excellent outcome as per Kyle's criteria.

    Conclusion: Although, not devoid of complications, modified short PFN results in good functional recovery of patients with intertrochanteric fractures of femur.

    Matched MeSH terms: Femur Head
  17. Abbas, A.A., Merican, A.M., Mohamad, J.A.
    Malays Orthop J, 2007;1(1):5-7.
    MyJurnal
    We report the outcome of 32 patients who underwent total hip replacement (THR) augmented with morsellized fresh frozen femoral head allografts and acetabular reconstruction cages. Nine patients underwent primary THR and 23 patients underwent revision THR. Follow-up ranged from two to 9 years. Two most common indications for the procedures as reported in literature were rheumatoid arthritis and aseptic loosening of the hip. All but one patient achieved good outcome with radiographs showing full incorporation of bone grafts and no evidence of loosening of the implants. Morsellized bone grafting used with acetabular reinforcement devices is valuable for addressing severe acetabular deficiencies.
    Matched MeSH terms: Femur Head
  18. Aytekin K, Esenyel CZ
    Malays Orthop J, 2018 Mar;12(1):45-47.
    PMID: 29725513 DOI: 10.5704/MOJ.1803.010
    Hip arthroplasty is an extremely satisfying treatment method for coxarthrosis which is in increasing use throughout the world. However, loosening of the prosthesis is a significant complication and to overcome this, ceramic liners are increasingly being selected. If the survival of ceramic surfaces is prolonged, there is a risk of fracture of the ceramic materials. New ceramic materials developed to overcome this problem are more resistant. The case presented here is of a patient in whom liner fracture developed following ceramic-ceramic hip arthroplasty. The ceramic femoral head was observed to have protruded into the defect created in the acetabular component. Acetabular revision was applied to the patient.
    Matched MeSH terms: Femur Head
  19. Law GW, Koh J, Yew A, Howe TS
    Malays Orthop J, 2020 Mar;14(1):7-17.
    PMID: 32296476 DOI: 10.5704/MOJ.2003.002
    Introduction: Medial migration is the paradoxical migration of the femoral neck element (FNE) superomedially against gravity with respect to the intramedullary component of the cephalomedullary device, increasingly seen in the management of pertrochanteric hip fractures with the intramedullary nail. We postulate that the peculiar anti-gravity movement of the FNE in the medial migration phenomenon stems from a ratcheting mechanism at the intramedullary nail-FNE interface, which should inadvertently produce unique wear patterns on the FNE that can be seen with high-powered microscopy. By examining the wear patterns on retrieved implants from patients with medial migration, our study aims to draw clinical correlations to the ratcheting mechanism hypothesis.

    Material and Methods: Four FNEs were retrieved from revision surgeries of four patients with prior intramedullary nail fixation of their pertrochanteric hip fractures complicated by femoral head perforation. The FNEs were divided into two groups based on whether or not there was radiographic evidence of medial migration prior to the revisions. Wear patterns on the FNEs were then assessed using both scanning electron microscopy and light microscopy.

    Results: Repetitive, linearly-arranged, regularly-spaced, unique transverse scratch marks were found only in the group with medial migration, corresponding to the specific segment of the FNE that passed through the intramedullary component of the PFNA during medial migration. These scratch marks were absent in the group without medial migration.

    Conclusion: Our findings are in support of a ratcheting mechanism behind the medial migration phenomenon with repetitive toggling at the intramedullary nail-FNE interface and progressive propagation of the FNE against gravity.

    Matched MeSH terms: Femur Head
  20. Ismiarto YD, Agradi P, Helmi ZN
    Malays Orthop J, 2019 Nov;13(3):60-65.
    PMID: 31890112 DOI: 10.5704/MOJ.1911.010
    Introduction: The radiographic classification for developmental dysplasia of hip to quantify the severity of disease consist of Tonnis and International Hip Dysplasia Institute (IHDI) classification. The Ossification center of the femoral head in DDH patient more than six months is still vague or eccentric, so the reliability of both classifications is still in question and especially is influenced by the experience of the observer. This study aims to test and compare interobserver reliability in evaluation of DDH patients using IHDI and Tonnis classification assessed by senior and junior orthopaedic residents which had different degree of experience. Materials and Methods: This study used retrospective analysis of pelvic supine AP view radiograph of DDH patients from 2014 to 2017. All three observer groups analysed the pelvis radiographs using Tonnis and IHDI classification. Inter and intra-observer reliability was measured by Cohen's and Fleiss Kappa method, respectively. Results: The Fleiss Kappa value for 15 radiographs of DDH patients assessed by senior residents using Tonnis and IHDI classification are 0.715 and 0.832 and result of Fleiss Kappa value assessed by junior residents are 0.577 and 0.845, respectively. Intra-observer reliability for Tonnis classification was lower in junior group compared to other two groups but showed almost perfect value in all groups for IHDI classification. Conclusion: Significantly different results were noted between junior and senior residents in assessing DDH severity, with higher diagnostic reliability in senior residents compared to junior residents. In general, junior resident has less clinical experiences in many aspects in comparison with the seniors.
    Matched MeSH terms: Femur Head
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