MyMedR

Fulltext AIDS-related progressive multifocal leukoencephalopathy in a patient presenting with cerebellar ataxia

Chang CY

Rev Soc Bras Med Trop, 2021;54:e02112021.

PMID: 34105634 DOI: 10.1590/0037-8682-0211-2021

Matched MeSH terms: Acquired Immunodeficiency Syndrome*

Fulltext Primary Mycobacterium avium Enteritis in a Patient Infected with Human Immunodeficiency Virus

Chang CY

Rev Soc Bras Med Trop, 2021;54:e03342021.

PMID: 34431951 DOI: 10.1590/0037-8682-0334-2021

Matched MeSH terms: Acquired Immunodeficiency Syndrome*

Fulltext Fuzzy Lambda-Max criteria weight determination for feature selection in clustering

Nurul Adzlyana Mohd Saadon, Rosma Mohd Dom, Nurazzah Abd Rahman

Pertanika Journal of Science & Technology, 2017;25(103):241-254.

MyJurnal

Clustering refers to reducing selected features involved in determining the clusters. Raw data might come with a lot of features, including unimportant ones. A hybrid similarity measure (discovered in 2014) used in selecting features can be improvised as it might select all the attributes, including insignificant ones. This paper suggests Fuzzy Lambda-Max to be used as a feature selection method since Lambda-Max is normally used in ranking of alternatives. A set of AIDS data is used to measure the performance. Results show that Fuzzy Lambda-Max has the ability to determine criteria weights and ranking the criteria. Hence, feature selection can be done by choosing only the important criteria.

Matched MeSH terms: Acquired Immunodeficiency Syndrome

AIDS and the surgeon

Cheong IKS

Family Physician, 1993;5:35-36.

Matched MeSH terms: Acquired Immunodeficiency Syndrome

Seventh IUVDT Regional Conference on Sexually Transmitted Diseases, Kuala Lumpur, 5-7 September 1991

Robinson AJ, Waugh MA

Genitourin Med, 1992 Apr;68(2):139-40.

PMID: 1582659

Matched MeSH terms: Acquired Immunodeficiency Syndrome*

Fulltext "I want the doctors to know that I am as bright as a candle": : Experiences with and Hopes for Doctor Interactions Among Malaysian Key Populations and People Living with HIV

Earnshaw VA, Cox J, Wong PL, Saifi R, Walters S, Azwa I, et al.

AIDS Behav, 2023 Jul;27(7):2103-2112.

PMID: 36472685 DOI: 10.1007/s10461-022-03942-9

Stigma in healthcare settings is a pernicious barrier to HIV prevention and treatment in contexts with strong HIV-related structural stigma. Previous work has documented substantial stigma towards key populations and people living with HIV (PLWH) among Malaysian doctors. The perspectives of Malaysian key populations and PLWH, however, remain understudied. In 2021, 34 Malaysian participants representing key populations and PLWH engaged in a photovoice study designed to qualitatively explore their experiences with and hopes for doctor interactions. Many participants reported stigma from their doctors, perceiving that doctors view them as not normal, sinful, misguided, and incapable. Several emphasized that they wear figurative masks to conceal aspects of themselves from doctors. Yet, many also remain hopeful for constructive relationships with doctors. They want their doctors to know that they are bright, capable, kind, and valuable. Interventions are needed to address stigma among doctors working in contexts with strong structural stigma.

Matched MeSH terms: Acquired Immunodeficiency Syndrome*

EBV-Associated Smooth Muscle Tumor in the Malar Area of an HIV-Positive Patient: A Case Report

Abidin NFZ, Rahman FA, Tuck Choon K, Tilakaratne WM

Head Neck Pathol, 2023 Sep;17(3):821-825.

PMID: 37209302 DOI: 10.1007/s12105-023-01560-y

BACKGROUND: EBV-associated smooth muscle tumors (EBV-SMTs) are rare and typically develop in individuals with a compromised immune system, particularly those who have acquired immunodeficiency syndrome (AIDS) or who have undergone organ transplants.

METHODS: We document a case of EBV-SMT in an HIV-positive 25-year-old man. The lesion was incised and assessed histologically and a panel of immune markers were performed. EBV association was demonstrated by in situ hybridization for EBV-encoded RNA (EBER-ISH).

RESULTS: Microscopically, the tumor composed of mildly pleomorphic, ovoid to spindled cells with numerous slit-like vascular channels. The tumor cells exhibited diffuse and strong immunoreactivity for smooth muscle actin (SMA) and focal positivity for h-caldesmon. EBER-ISH of the tumor cells revealed strong positive nuclear signals.

CONCLUSION: The histopathological features of EBV-SMT do not conform to either benign or malignant SMTs and it has a peculiar predilection to develop at sites unusual for leiomyoma or leiomyosarcoma. The key diagnostic features of EBV-SMT include history of immunosuppression, histologic evidence of primitive and mildly pleomorphic cells maintaining blunt nuclear features in most areas, and positivity for EBER-ISH.

Matched MeSH terms: Acquired Immunodeficiency Syndrome*

Medicine in Malaysia: sexually transmitted diseases and AIDS

Rokiah I

Med J Malaysia, 1995 May;50 Suppl A:S42-5.

PMID: 10968014

Matched MeSH terms: Acquired Immunodeficiency Syndrome/diagnosis*; Acquired Immunodeficiency Syndrome/therapy*

Observations on the problems of HIV infection in Malaysia

Brettle RP

J Infect, 1992 Jan;24(1):101-2.

PMID: 1548408

Matched MeSH terms: Acquired Immunodeficiency Syndrome/epidemiology*; Acquired Immunodeficiency Syndrome/prevention & control

[Malaysia: loser in the fight against AIDS]

J Sykepleien, 1994 Feb 15;82(3):36.

PMID: 7946737

Matched MeSH terms: Acquired Immunodeficiency Syndrome/prevention & control*; Acquired Immunodeficiency Syndrome/transmission

Fulltext Penicillium marneffei infection in an AIDS patient--a first case report from Malaysia

Rokiah I, Ng KP, Soo-Hoo TS

Med J Malaysia, 1995 Mar;50(1):101-4.

PMID: 7752960

We report a 39-year-old male who presented with tuberculous meningitis and was found also to be HIV-infected. In the course of his illness, he developed multiple opportunistic infections such as herpes genitalis, oesophageal candidiasis, CMV retinitis and finally succumbed to Penicillium marneffei septicaemia.

Matched MeSH terms: Acquired Immunodeficiency Syndrome/complications*; Acquired Immunodeficiency Syndrome/epidemiology

Fulltext HIV in south and South-East Asia

Yasmin AM

Med J Malaysia, 1997 Dec;52(4):311-2.

PMID: 10968105

Matched MeSH terms: Acquired Immunodeficiency Syndrome/epidemiology

Fulltext A COVID-19 conference at AIDS 2020: Virtual

Pozniak A, Bekker LG, Kamarulzaman A, Gandhi M, Horton R, Das P, et al.

Lancet, 2020 05 23;395(10237):1598-1599.

PMID: 32359401 DOI: 10.1016/S0140-6736(20)31026-6

Matched MeSH terms: Acquired Immunodeficiency Syndrome*

Pharmacist-Involved Antiretroviral Stewardship Programs in People Living with HIV/AIDS: A Systematic Review

Ahmed A, Tanveer M, Dujaili JA, Chuah LH, Hashmi FK, Awaisu A

AIDS Patient Care STDS, 2023 Jan;37(1):31-52.

PMID: 36626156 DOI: 10.1089/apc.2022.0192

People living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS; PLWHA) frequently encounter antiretroviral (ARV) therapy-related problems. Clinical pharmacists with specialized training in ARV stewardship play an important role in managing these problems. However, there is a paucity of evidence to clarify the impact of clinical pharmacists' interventions on managing ARV therapy-related problems in PLWHA. Therefore, we aim to systematically review the literature to determine the nature and impact of pharmacists' interventions on managing medication-related problems in PLWHA. The review protocol was registered on International Prospective Register of Systematic Reviews (PROSPERO; CRD42020173078). Relevant records were identified from six electronic bibliographic databases (PubMed, Embase, EBSCOhost, ProQuest, Scopus, and the Cochrane Central Register) from their inception until September 2022. We included all randomized and nonrandomized interventional studies that were published in English. After the abstract and full-text screening, data were extracted from the selected studies, and the quality of the studies was assessed. The electronic database search and citation tracking identified two thousand and three citations. The review included 21 of these studies, involving 2998 PLWHA, published between 2014 and 2022. Pharmacists' interventions, working alone or in a multi-disciplinary team, comprised ARV medication review, management of adverse drug reactions (ADRs), therapeutic drug monitoring, prevention of drug interactions, and provision of drug information to PLWHA or the health care team. The pharmacist-involved interventions significantly reduced incorrect/incomplete ARV regimens, drug interactions, incorrect dosages, duplicate therapy, polypharmacy, administration errors, missing medication, wrong formulation, ADRs, and prescribing errors. Most studies reported that physicians usually accept more than 90% of the pharmacists' recommendations. ARV medication-related problems remain highly prevalent in PLWHA. Pharmacist-led interventions and stewardship significantly reduce ARV therapy-related problems in PLWHA and are widely accepted by physicians. Dedicated pharmacists with specialized training and credentialing in infectious diseases or HIV/AIDS have a great potential to improve health outcomes in PLWHA.

Matched MeSH terms: Acquired Immunodeficiency Syndrome*

Fulltext Long-term safety of COVID vaccination in individuals with idiopathic inflammatory myopathies: results from the COVAD study

Doskaliuk B, Ravichandran N, Sen P, Day J, Joshi M, Nune A, et al.

Rheumatol Int, 2023 Sep;43(9):1651-1664.

PMID: 37351634 DOI: 10.1007/s00296-023-05345-y

Limited evidence on long-term COVID-19 vaccine safety in patients with idiopathic inflammatory myopathies (IIMs) continues to contribute to vaccine hesitancy. We studied delayed-onset vaccine adverse events (AEs) in patients with IIMs, other systemic autoimmune and inflammatory disorders (SAIDs), and healthy controls (HCs), using data from the second COVID-19 Vaccination in Autoimmune Diseases (COVAD) study. A validated self-reporting e-survey was circulated by the COVAD study group (157 collaborators, 106 countries) from Feb-June 2022. We collected data on demographics, comorbidities, IIM/SAID details, COVID-19 history, and vaccination details. Delayed-onset (> 7 day) AEs were analyzed using regression models. A total of 15165 respondents undertook the survey, of whom 8759 responses from vaccinated individuals [median age 46 (35-58) years, 74.4% females, 45.4% Caucasians] were analyzed. Of these, 1390 (15.9%) had IIMs, 50.6% other SAIDs, and 33.5% HCs. Among IIMs, 16.3% and 10.2% patients reported minor and major AEs, respectively, and 0.72% (n = 10) required hospitalization. Notably patients with IIMs experienced fewer minor AEs than other SAIDs, though rashes were expectedly more than HCs [OR 4.0; 95% CI 2.2-7.0, p

Matched MeSH terms: Simian Acquired Immunodeficiency Syndrome*

Fulltext Tuberculosis in AIDS patients

Nissapatorn V, Lee C, Ithoi I, Yik FM, Abdullah KA

Malays J Med Sci, 2003 Jan;10(1):60-4.

PMID: 23365502 MyJurnal

Tuberculosis is the top agenda among opportunistic diseases and the most leading cause of death in HIV/AIDS patients. A total of 406 AIDS patients were recruited in this retrospective and descriptive study. 123/406 (30.3%) were diagnosed as AIDS-related tuberculosis (TB). Their age range from 17 to 69 years with a mean (±SD) of 37.2 (±9.51. There were significant association between occupation, or mode of HIV transmission and tuberculosis infection (p< 0.05). Pulmonary tuberculosis 104/123 (84.6%) was the most common disease location among TB patients. We found the significant association between the clinical presentations i.e. fever, cough, sputum or hemoptysis and TB patients (p<0.05), moreover, the level of CD4 cell count plays a significant role in association with the disease (p<0.05) in this study.

Matched MeSH terms: Acquired Immunodeficiency Syndrome*

The HIV/AIDS epidemic country paper: Malaysia

Huang M, Hussein H

AIDS Educ Prev, 2004 Jun;16(3 Suppl A):100-9.

PMID: 15262569

Since the first case of HIV/AIDS was identified in 1986 in Malaysia, the number of infected individuals has increased steadily each year, so that by the end of 2002 the cumulative number of people living with HIV/AIDS was 57,835 (51,256 with HIV and 6,579 with AIDS), with 5,676 AIDS deaths. The epidemic in Malaysia, currently in a concentrated epidemic stage, is primarily fueled by drug use, but there is ample evidence that heterosexual transmission has increased over the last few years. A strategic plan that includes prevention, care, support, and treatment run by both the government and nongovernmental organizations has been in place since the beginning of the epidemic. However, Malaysia will need to take a more pragmatic approach to reduce new infections (which numbered 19 each day in 2002) among the youth on whom the country relies for development. Leaders need to recognize that HIV/AIDS is not just a health issue, but also a socioeconomic concern that can eliminate all the developmental gains achieved over the years. Working together, Malaysians can overcome the epidemic, but there is a need to act quickly and to act in effective ways so that the devastating effects (already evident in the number of AIDS orphans and widows) can be reduced.

Matched MeSH terms: Acquired Immunodeficiency Syndrome/epidemiology; Acquired Immunodeficiency Syndrome/prevention & control; Acquired Immunodeficiency Syndrome/transmission

Laboratory investigations of sexually transmitted diseases (excluding AIDS)

Ngeow YF

Family Practitioner, 1986;9:11-16.

Matched MeSH terms: Acquired Immunodeficiency Syndrome

Control of acquired immunodeficiency syndrome: recent developments

Ilina I

Family Physician, 1993;5:37-41.

Matched MeSH terms: Acquired Immunodeficiency Syndrome

AIDS in pregnancy - the growing threat

Ravi C

Family Physician, 1991;3:33-38.

Matched MeSH terms: Acquired Immunodeficiency Syndrome