Displaying publications 1 - 20 of 46 in total

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  1. CHAN KE, THURAISINGHAM V
    Med J Malaya, 1963 Mar;17:163-9.
    PMID: 14019984
    Matched MeSH terms: Anemia, Hemolytic*; Anemia, Hemolytic, Autoimmune*
  2. Lopez CG, Lie-Injo Luan Eng
    Med J Malaya, 1969 Dec;24(2):101-6.
    PMID: 4244132
    Matched MeSH terms: Anemia, Hemolytic/etiology*; Anemia, Hemolytic/genetics*
  3. Chee YC, Gill DS, Poh SC
    Med J Malaysia, 1978 Dec;33(2):154-5.
    PMID: 755168
    Matched MeSH terms: Anemia, Hemolytic, Autoimmune/complications*
  4. Abdul Rashid AM, Md Noh MSF
    BMC Neurol, 2017 Aug 25;17(1):165.
    PMID: 28841841 DOI: 10.1186/s12883-017-0944-9
    BACKGROUND: Non-traumatic, spontaneous subarachnoid hemorrhage occurs in approximately 85% of cases where there is a ruptured saccular aneurysm. An additional 10% of cases arise from non-aneurysmal peri-mesencephalic hemorrhages.

    CASE PRESENTATION: We report a rare case of a young female, with underlying Evans syndrome, who was initially thought to have non-hemorrhagic stroke, eventually diagnosed having isolated non-traumatic, non-aneurysmal convexal subarachnoid haemorrhage.

    CONCLUSIONS: Spontaneous non-traumatic, non-aneurysmal convexal subarachnoid hemorrhage is a rare entity - of which there are multiple possible etiologies.

    Matched MeSH terms: Anemia, Hemolytic, Autoimmune*
  5. Ng SC, Wong KK, Raman S, Bosco J
    Eur J Obstet Gynecol Reprod Biol, 1990 Oct;37(1):83-5.
    PMID: 2376282
    A young primigravida had idiopathic warm antibody (IgG) autoimmune haemolytic anaemia (AIHA) occurring in the third trimester of pregnancy. Her haemolytic process was responsive to steroid therapy and no transfusion was needed. She delivered a healthy baby with no evidence to haemolysis, though his red cells were coated with IgG which was probably of maternal origin.
    Matched MeSH terms: Anemia, Hemolytic, Autoimmune/complications; Anemia, Hemolytic, Autoimmune/diagnosis*; Anemia, Hemolytic, Autoimmune/drug therapy
  6. LIE-INJOLUAN EN, PILLAY RP
    Acta Haematol., 1964 May;31:282-8.
    PMID: 14172696
    Matched MeSH terms: Anemia, Hemolytic*; Anemia, Hemolytic, Autoimmune*
  7. Ainoon O, Boo NY, Yu YH, Cheong SK, Hamidah HN
    Hematology, 2006 Apr;11(2):113-8.
    PMID: 16753852 DOI: 10.1080/10245330500155184
    A 2-year-old Chinese boy was referred to Hospital UKM for investigation of recurrent episodes of dark-coloured urine and pallor since birth. He was born prematurely at 34 weeks gestation and developed severe early-onset neonatal jaundice requiring exchange blood transfusion. Screening at birth showed Glucose-6-phosphate dehydrogenase (G6PD) deficiency. On admission, physical examination revealed pallor, jaundice and mild hepatomegaly. Results of laboratory investigations showed a hemoglobin level of 11.0 g/dl with a hemolytic blood picture, reticulocytosis of 20% and red cell G6PD activity reported as undetectable. The patient's DNA was analysed for G6PD mutations by PCR-based techniques and DNA sequencing and results showed a 24 bp deletion of nucleotide 953-976 in the exon 9 of the G6PD gene. DNA analysis was also performed on blood samples of the patient's mother and female sibling confirming their heterozygous status, although both showed normal red cell G6PD activity levels. The patient was discharged well and his parents were appropriately advised on the condition and the importance of taking folic acid regularly. This is a first case report in Malaysia of G6PD deficiency causing chronic-hemolytic anemia. The rare 24 bp deletion causes the G6PD Nara variant, previously reported only in two other unrelated males, a Japanese and a Portuguese both with chronic hemolytic anemia.
    Matched MeSH terms: Anemia, Hemolytic/etiology*; Anemia, Hemolytic, Congenital Nonspherocytic/diagnosis; Anemia, Hemolytic, Congenital Nonspherocytic/genetics*
  8. Pettit JHS, Chin J
    Lepr Rev, 1964 Jul;35(4):149-56.
    PMID: 14177689
    In a survey of over 1,000 patients with leprosy, 47 cases ( 4.4 per cent) were found to have glucose-6-phosphate dehydrogenase deficiency. A controlled clinical study suggests that such a deficiency does not modify the overall response to therapy but may predispose to a greater tendency to leprosy reactions. All patients were receiving 600 to 800 mgm. of sulphone per week and none had a frank haemolytic anaemia.
    Matched MeSH terms: Anemia, Hemolytic*
  9. VELLA F
    Med J Malaya, 1959 Jun;13:298-308.
    PMID: 13841622
    Matched MeSH terms: Anemia, Hemolytic/etiology*
  10. Mak WW, Adrian MM, Ahlam K
    Med J Malaysia, 2019 Oct;74(5):443-344.
    PMID: 31649226
    Brucellosis is a rare zoonotic infection caused by small, fastidious Gram-negative coccobacilli of the genus Brucella that may be associated with haemolytic complications including thrombotic microangiopathy and haemolytic anaemia. We describe a patient with culture confirmed brucellosis who presented with malaise, high grade fever, hepatosplenomegaly and Coombs-positive autoimmune haemolytic anaemia. The patient was successfully treated with combination of doxycycline and rifampicin with no further episodes of relapses or haemolysis. Although rare, the possibility of brucellosis should always be kept in mind in patients with risk factors who present with haemolysis and endemic area.
    Matched MeSH terms: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune
  11. Palaniappan S, Ramanaidu S
    Med J Malaysia, 2012 Jun;67(3):326-8.
    PMID: 23082427 MyJurnal
    Matched MeSH terms: Anemia, Hemolytic, Autoimmune/complications*; Anemia, Hemolytic, Autoimmune/diagnosis; Anemia, Hemolytic, Autoimmune/drug therapy
  12. Wan Haslindawani Wan Mahmood, Rapiaah Mustaffa
    MyJurnal
    Introduction: Multiply transfused patients are frequently subjected to platelet alloimmunization. These platelet alloantibodies produced can result in refractoriness to platelet transfusion. Material and Methods: Ninety five thrombocytopenic (platelet count
    Matched MeSH terms: Anemia, Hemolytic
  13. Fadilah SA, Hamidah AB, Cheong SK
    Med J Malaysia, 1999 Sep;54(3):383-5.
    PMID: 11045070
    The presence of serum cold agglutinin can be the initial presentation of lymphoproliferative diseases. Conditions with persistent cold agglutinins are a spectrum of diseases that vary from benign lymphoproliferation of the "autoimmune-like chronic cold agglutinin disease" to malignant lymphoma. We report a case of a 72-year-old woman who presented with severe anaemia, hepatosplenomegaly and episodes of peripheral haemagglutination precipitated by cold exposure. The haemoglobin was 5.6 g/dL with a cold agglutinin titer of 1:256 at 4 degrees C and 1:8 at room temperature (30 degrees C). The cold agglutinin showed anti-I specificity and kappa light chain restriction. Peripheral blood showed atypical lymphoid cells with a B-cell immunophenotype. Immunoglobulin gene rearrangement study by polymerase chain reaction (PCR) showed an amplified band at 100 bp, consistent with a clonal proliferation of B-lymphocytes. We believe that our patient had cold antibody haemolytic anaemia as the initial presentation of a low-grade non-Hodgkin's lymphoma. The association of cold antibody haemolytic anaemia with low-grade B-cell lymphoma is unusual.
    Matched MeSH terms: Anemia, Hemolytic/blood; Anemia, Hemolytic/etiology
  14. Eng LL, Lopez CG, Eapen JS, Eravelly J, Wiltshire BG, Lehmann H
    J Med Genet, 1972 Sep;9(3):340-3.
    PMID: 5079107 DOI: 10.1136/jmg.9.3.340
    Matched MeSH terms: Anemia, Hemolytic, Congenital Nonspherocytic/blood*; Anemia, Hemolytic, Congenital Nonspherocytic/enzymology; Anemia, Hemolytic, Congenital Nonspherocytic/genetics; Anemia, Hemolytic, Congenital Nonspherocytic/urine
  15. Hamidah A, Thambidorai CR, Jamal R
    PMID: 16124452
    We describe a patient with Evans syndrome (autoimmune hemolytic anemia and autoimmune thrombocytopenia) who was refractory to steroids and intravenous immunoglobulin. She responded to splenectomy and has remained in clinical remission for 3 years. In the majority of cases, splenectomy rarely induces a durable remission but it may be beneficial in a small group of patients, hence should be considered as alternative therapy in the management of these patients.
    Matched MeSH terms: Anemia, Hemolytic, Autoimmune/diagnosis; Anemia, Hemolytic, Autoimmune/therapy*
  16. Chew FL, Tajunisah I
    Ocul Immunol Inflamm, 2009 Nov-Dec;17(6):394-5.
    PMID: 20001258 DOI: 10.3109/09273940903260204
    To describe a case of retinal phlebitis associated with autoimmune hemolytic anemia.
    Matched MeSH terms: Anemia, Hemolytic, Autoimmune/complications*; Anemia, Hemolytic, Autoimmune/therapy
  17. Jayaranee S, Ramesh P, Nadesan V
    Singapore Med J, 2002 Aug;43(8):421-2.
    PMID: 12507029
    Immune haemolysis following renal transplantation has been reported and known causes include infection, medication and metabolic disturbances (1,2). Autoimmune haemolysis after renal transplantation secondary to ABO minor mismatch is an uncommon but important cause that should be considered in the differential diagnosis of post-transplantation haemolysis. A case of haemolytic anaemia caused by graft versus host antibody formation is presented. We suggest that direct Coomb's test should be done as a routine in all cases of ABO mismatch renal transplantation and red cells compatible with both donor and recipient or group "O" packed cells should be transfused if transfusion is indicated.
    Matched MeSH terms: Anemia, Hemolytic, Autoimmune/etiology*; Anemia, Hemolytic, Autoimmune/immunology
  18. Leong CF, Cheong SK, Fadilah SA
    Med J Malaysia, 1999 Dec;54(4):517-9.
    PMID: 11072473
    A 56-year-old Chinese lady with valvular heart disease and atrial fibrillation was referred to us from a private hospital for further management of autoimmune haemolytic anaemia. Physical examination and laboratory investigations did not support the diagnosis of haemolytic anaemia. However, direct antiglobulin test (DAT) was strongly positive with anti-IgG and negative with anti-C3d. There was also mild anaemia and reticulocytosis, which was attributable to persistent haematuria. The DAT became positive after commencing Unasyn and cessation was associated with decreasing reactivity of the positive DAT. We believe that the positive DAT in this patient was most likely due to the Unasyn therapy.
    Matched MeSH terms: Anemia, Hemolytic/diagnosis
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