MyMedR

Response to: Stroke and infective endocarditis

Tan YA, Ng KC, Cheo SW, Low QJ, Chia YK

QJM, 2020 07 01;113(7):517-518.

PMID: 32191336 DOI: 10.1093/qjmed/hcaa099

Matched MeSH terms: Endocarditis*; Endocarditis, Bacterial*

Fulltext On acute endocarditis following acute rheumatism

Robertson M

Journal of the Straits Medical Association, 1892;3:20-31.

Matched MeSH terms: Endocarditis

Pattern of antibiotic prophylaxis practice for dental procedures in children with congenital heart disease

Sharif JM, Raja Shahardin RZ, Sockalingam G

J Indian Soc Pedod Prev Dent, 2020 7 3;38(2):126-131.

PMID: 32611857 DOI: 10.4103/JISPPD.JISPPD_235_18

Background: Various antibiotic prophylaxis guidelines have been published such as the American Heart Association 2007, British Society for Antimicrobial Chemotherapy 2006, National Institute for Health and Clinical Excellence 2008, European Society of Cardiology 2015, and in Malaysia, the National Antibiotic Guideline 2014 and Clinical Practice Guidelines for the Prevention, Diagnosis and Management of Infective Endocarditis 2017. The aim of the study is to determine the pattern of antibiotic prophylaxis practice for dental procedure in children with congenital heart disease (CHD) at the Department of Paediatric Dentistry, Kuala Lumpur Hospital.

Materials and Methods: A comparative cross-sectional study of dental records from 2010 to 2015 was done by collecting data on the source and reason of referral, types of heart condition, dental procedure, and antibiotic given.

Results: There were 210 patients; 69.5% had acyanotic CHD, 21.9% cyanotic CHD, 6.7% repaired CHD with residual defects, and 1.9% with previous infective endocarditis. Slightly more than 58% were referred from government doctors (pediatric cardiologist and National Heart Institute). The common cause for referral was dental assessment (47.6%). Antibiotics were prescribed to 23.3% (49/210) patients, of which, 34.7% was given ampicillin or amoxicillin/clavulanic acid. About 96% of cyanotic heart cases undergoing invasive dental procedures were prescribed antibiotic prophylaxis. Almost 31% were prescribed with antibiotic prophylaxis even though it was not indicated.

Conclusion: This study shows that there is variability in prescribing antibiotic prophylaxis, and it is important for dental clinicians to standardize the practice of giving antibiotic prophylaxis.

Matched MeSH terms: Endocarditis*; Endocarditis, Bacterial*

Fulltext Preference of dental practitioner on antibiotic prophylaxis for infective endocarditis guidelines: the cohort of Klang valley

Mohd Nazrin Mohd Isa, Nor Azura Ahmad Tarmidzi, Norzalina Ghazali, Nalisha Mohamed Ramli, Ammar Yaseer Abdul Hakim@Abdul Khakin

International Medical Journal Malaysia, 2017;16(21):9-9.

MyJurnal

Antibiotic prophylaxis guidelines for infective endocarditis have been regularly
revised and modified based on current scientific evidence. These guidelines commonly regarded as
standard of care and determine the medicolegal standards. The aim of this study was to elicit the
current practice of prophylaxis antibiotic for Infective endocarditis among general dental
practitioner in Klang Valley. (Copied from article).

Matched MeSH terms: Endocarditis; Endocarditis, Bacterial

Fulltext Painful nodules on the fingers and toes

Loh KY

Aust Fam Physician, 2007 Jul;36(7):554.

PMID: 17619674

A 25 year old college student with a past history of congenital heart disease presented with high grade fever and palpitations. He complained of painful red nodules on his finger pulp and his toes.

Matched MeSH terms: Endocarditis/diagnosis*; Endocarditis/drug therapy; Endocarditis/physiopathology

Factors associated with in-hospital mortality among infective endocarditis patients

Ho YH, Lim CT, Chua CZF, Chow HB, Chua HH, Fong AYY

Med J Malaysia, 2023 Nov;78(6):743-750.

PMID: 38031215

INTRODUCTION: Despite recent advancements in the diagnosis and management of infective endocarditis (IE), it is associated with substantial morbidity and mortality. Our study objective is to determine the factors associated with in-hospital mortality in IE patients among the local population.

MATERIALS AND METHODS: All IE patients who were diagnosed with definite or possible IE and were treated at Sarawak Heart Centre from 1st January 2020 to 31st December 2022 were recruited. We examined the demographic features of the subjects and the factors that contributed to in-hospital mortality. Multivariate logistic regression was used to analyse the associated factors and in-hospital mortality.

RESULTS: Our study population comprised a total of 37 patients with a mean age of 46.4 years and male predominance. The in-hospital mortality rate of IE in this study was 44.4%. Haemodynamic instability and anaemia were found to be strong predictors of IE survival outcome, with an odds ratio of 51.5 and 35.7 respectively. Patients with vascular phenomenon and heart failure were at 10.5- and 6.0-times higher odds of dying, however, these two associations were found to be not statistically significant.

CONCLUSION: The in-hospital mortality due to IE in our study was among the highest in developing countries. Factors of hypotension and optimal response to individual hemodynamic parameters may confer lower mortality. While anaemia is demonstrable as a risk factor for inpatient mortality, a target has yet to be reasonably established.

Matched MeSH terms: Endocarditis*; Endocarditis, Bacterial*

Fulltext Candida sake--a rare cause of fungal endocarditis

Anuradha S, Agarwal SK, Prakash A, Singh NP, Kaur R

Med J Malaysia, 2008 Mar;63(1):75-6.

PMID: 18935744

Matched MeSH terms: Endocarditis/microbiology*

Thrombotic thrombocytopenic purpura-like syndrome associated with arcanobacterium pyogenes endocarditis in a post-transplant patient: A case report

Andy Tang SO, Leong TS, Ruixin T, Chua HH, Chew LP

Med J Malaysia, 2018 10;73(5):344-346.

PMID: 30350823 MyJurnal

Systemic Arcanobacterium pyogenes is a rare bacterial infection in humans.1The diagnosis of thrombotic thrombocytopenic purpura (TTP)-like syndrome and infective endocarditis (IE) is often elusive. We report a case of TTP-like syndrome associated with A. pyogenes endocarditis in a post-allogenic transplant patient.

Matched MeSH terms: Endocarditis; Endocarditis, Bacterial

Sudden death due to infective endocarditis caused by Streptococcus constellatus: A case report

Zamasry MS, Hilmi Z, Mohd Yusof MYP, Razali HSA, Nawawi H, Mahmood MS

Trop Biomed, 2019 Dec 01;36(4):845-849.

PMID: 33597456

Infective endocarditis (IE) is a relatively uncommon disease, but has been challenging to diagnose over the years. With the increasing incidence, variety of causative agents and the resistance of microorganisms towards antibiotics, there is still an occurrence of sudden death due to undiagnosed IE. The most common microorganism causing IE is Staphylococcus aureus. However, there is increasing prevalence of other microorganisms causing IE. This case report highlights a case of sudden death due to IE caused by a rare pathogen, Streptococcus constellatus which belongs to the Streptococcus anginosus group (Milleri group). A study noted the crude incidence of IE in 6 world regions ranged between 1.5 and 11.6 cases per 100,000 people. To date, there has been no previous report on sudden death due to IE caused by Streptococcus constellatus in Malaysia, neither in the forensic nor clinical setting. This case report underlined the characteristics and pathological features of this microorganism. The increasing incidence and variety of causative organisms in IE are important public health issues. It is vital for future studies to examine the risk factors of IE related to Streptococcus constellatus, to enhance better understanding, insight and awareness regarding the course of this disease. This in turn may facilitate preventive measures to avoid morbidity and mortality from this condition.

Matched MeSH terms: Endocarditis, Bacterial/diagnosis*; Endocarditis, Bacterial/microbiology

Surgical management of patent ductus arteriosus with endocarditis

Kareem BA, Kamarulzaman H, Koh GT

Ann Thorac Surg, 2010 Nov;90(5):1703-5.

PMID: 20971300 DOI: 10.1016/j.athoracsur.2010.04.105

A 9-year-old boy with patent ductus arteriosus complicated by infective endocarditis had not responded to antibiotic therapy and was referred to our institution. He had persistent fever and a chest roentgenogram demonstrated the presence of left lung pneumonic consolidation. An echocardiogram showed the presence of large vegetation in the pulmonary artery at the ductal opening. We successfully performed an open ductal ligation with the aid of cardiopulmonary bypass through a sternotomy and proceeded to resect the vegetation. We completed the procedure with reconstruction of the pulmonary artery. The postoperative course was uneventful. The patient was discharged after a week.

Matched MeSH terms: Endocarditis, Bacterial/surgery*

Fulltext Infective endocarditis of the aorta valve--demonstration of valvular vegetations by M-Mode and Cross-Sectional echocardiography

Ng WH

Med J Malaysia, 1981 Dec;36(4):205-8.

PMID: 7334953

The ability to visualise valvular vegetations by echocardiography is a significant advantage in the management oj patients with infective endocarditis. In this report the M-Mode and Cross-Sectional echocardiographic appearances oj infective endocarditis affecting the aortic valve are described. The uses and limitations of echocardiography are discussed.

Matched MeSH terms: Endocarditis, Bacterial/diagnosis*

A review of heart valve disease research in Malaysia

Khoo PLZ, Poon JS, Tan GJS, Yahya A, Chan KMJ

Med J Malaysia, 2020 11;75(6):722-730.

PMID: 33219184

INTRODUCTION: Heart valve disease comprises a cluster of conditions affecting the aortic, mitral, pulmonary and tricuspid valves. This paper reviews all the research on heart valve disease in Malaysia published between the years 2000- 2016.

METHODS: The methodology was based on the search process described in the paper, "Bibliography of clinical research in Malaysia: methods and brief results". The search databases included PubMed, Scopus and several Malaysian journals such as MyJurnal and UKM Journal Repository, by using the following keywords: (heart valve disease OR infective endocarditis OR rheumatic heart disease) and (Malaysia).

RESULTS: In all 94 papers were identified of which 39 papers were selected and reviewed on the basis of their relevance. The local studies contributed to the knowledge and understanding of the epidemiology, aetiology, pathophysiology, clinical presentations, investigations, treatment, and outcomes of heart valve disease in the country.

DISCUSSION: The clinical relevance of the studies performed in the country is discussed along with recommendations for future research.

Matched MeSH terms: Endocarditis; Endocarditis, Bacterial

Fulltext Gram-negative infection as an unusual cause of endocarditis in a hemodialysis patient

Balakrishnan S, Aamar A, Rhee S, Zakaria S, Khaliq W

Med J Malaysia, 2016 Jun;71(3):152-3.

PMID: 27495894

Gram-negative endocarditis is rare and it has high mortality if there is a delay in diagnosis and treatment. Gram-negative organisms should be considered in the differential diagnosis of IE in hemodialysis patients. Central lineassociated bloodstream infections (CLABSIs) can be prevented by following sterile measures during catheter insertion and proper management of catheter site.

Matched MeSH terms: Endocarditis*

Woman With Rashes

Mustafa MA, Fauzi MH, Wahab SFA

Ann Emerg Med, 2020 06;75(6):776-794.

PMID: 32471577 DOI: 10.1016/j.annemergmed.2019.12.004

Matched MeSH terms: Endocarditis/complications; Endocarditis/diagnosis*; Endocarditis/drug therapy*

Fulltext Recurrent cerebral infarcts secondary to marantic endocarditis in a patient with adenocarcinoma of the lung

Tai ML, Tan EC, Ang CC, Liam CK

Singapore Med J, 2016 Sep;57(9):524-5.

PMID: 27663211 DOI: 10.11622/smedj.2016157

Matched MeSH terms: Endocarditis/complications*; Endocarditis, Non-Infective/complications*

A rare case of mycotic pseudoaneurysm in a patient post Rastelli procedure with infective endocarditis

Chua C, Then K, Mohd Khalid KF

Cardiol Young, 2023 May;33(5):827-828.

PMID: 36511131 DOI: 10.1017/S1047951122002931

Mycotic pseudoaneurysm secondary to infective endocarditis is an uncommon complication in CHD with conduit placement. We report a case of late presentation of bacterial infective endocarditis with pseudoaneurysm in an 8-year-old girl with underlying pulmonary atresia with ventricular septal defect, post Rastelli procedure done at the age of 3 years old.

Matched MeSH terms: Endocarditis*; Endocarditis, Bacterial*

Fulltext A forgotten clinical sign making a comeback

Chiam KH, A Hing CT, Low LL

Med J Malaysia, 2014 Feb;69(1):40-1.

PMID: 24814630 MyJurnal

We report a case of Staphylococcus aureus infective endocarditis in a patient presenting with fever and rare cutaneous manifestations of Osler Nodes and Janeway Lesions. There had not been any distinct risk factors. His echocardiography subsequently revealed vegetation at the anterior mitral valve leaflet. As Staphylococcus aureus infective endocarditis is of utmost significance in morbidity and mortality, a sharp clinical acumen and follow up investigations is required alongside a prolonged course of antibiotics. Our patient was then started on intravenous cloxacillin for 28 days and gentamicin for 5 days to which he made good progress and recovery.

Matched MeSH terms: Endocarditis; Endocarditis, Bacterial

Spontaneous involution of an atrial myxoma complicated by bacterial endocarditis

Rajadurai J, Rajadurai P, Pasamanickam K

Aust N Z J Med, 1993 Jun;23(3):311-2.

PMID: 8352712

Matched MeSH terms: Endocarditis, Bacterial/complications*

Fulltext A case of left atrial myxoma

Segasothy M

Med J Malaysia, 1982 Sep;37(3):221-2.

PMID: 7177002

Left atrial myxoma almost always arises in the inter-atrial septum. A case is described where it arose from the posterior wall of the left atrium. Clinical presentation was suggestive of mitral stenosis and sub-acute bacterial endocarditis and diagnosis was arrived at necropsy.

Matched MeSH terms: Endocarditis, Subacute Bacterial/diagnosis

Fulltext Distinct Biological Potential of Streptococcus gordonii and Streptococcus sanguinis Revealed by Comparative Genome Analysis

Zheng W, Tan MF, Old LA, Paterson IC, Jakubovics NS, Choo SW

Sci Rep, 2017 06 07;7(1):2949.

PMID: 28592797 DOI: 10.1038/s41598-017-02399-4

Streptococcus gordonii and Streptococcus sanguinis are pioneer colonizers of dental plaque and important agents of bacterial infective endocarditis (IE). To gain a greater understanding of these two closely related species, we performed comparative analyses on 14 new S. gordonii and 5 S. sanguinis strains using various bioinformatics approaches. We revealed S. gordonii and S. sanguinis harbor open pan-genomes and share generally high sequence homology and number of core genes including virulence genes. However, we observed subtle differences in genomic islands and prophages between the species. Comparative pathogenomics analysis identified S. sanguinis strains have genes encoding IgA proteases, mitogenic factor deoxyribonucleases, nickel/cobalt uptake and cobalamin biosynthesis. On the contrary, genomic islands of S. gordonii strains contain additional copies of comCDE quorum-sensing system components involved in genetic competence. Two distinct polysaccharide locus architectures were identified, one of which was exclusively present in S. gordonii strains. The first evidence of genes encoding the CylA and CylB system by the α-haemolytic S. gordonii is presented. This study provides new insights into the genetic distinctions between S. gordonii and S. sanguinis, which yields understanding of tooth surfaces colonization and contributions to dental plaque formation, as well as their potential roles in the pathogenesis of IE.

Matched MeSH terms: Endocarditis; Endocarditis, Bacterial

Displaying publications 1 - 20 of 57 in total