Displaying all 18 publications

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  1. Arokiasamy JT
    Med J Malaysia, 1994 Jun;49(2):109-12.
    PMID: 8090087
    http://www.e-mjm.org/1994/v49n2/Accidental_Poisoning.pdf
    Matched MeSH terms: Poisoning/etiology*
  2. Lim HH, Abu Bakar CM
    Med J Malaysia, 1983 Sep;38(3):212-6.
    PMID: 6672564
    A study was carried out by the Factories and Machinery Department of Malaysia to assess the problem ofoccupational exposure to inorganic lead in Malaysian battery workers. The eight factories studied were divided into two categories: large, multinational subsidiaries with good industrial hygiene measures and small, locally-owned companies with poor hygiene features. A total of 251 workers (221 males and 30 females) were included in the study. Personal air sampling showed that 47% of the samples in the small factories had lead-in-air levels exceeding 150 ug/m3, compared unth. 29% in the larger establishments. The highest air lead levels were found in the cutting, pasting/mixing and battery assembly sections. 86.7% ofthe female workers and 62.2% of the male workers in the smaller factories had blood lead concentrations above the proposed limits of 70 ug/100 ml (males) and 40 ug/100 ml (females). In contrast, only 7.6% of the male workers in the larger factories had blood lead levels exceeding the proposed limits. Three workers also had positive signs or symptoms on clinical examination. Legislation of specific regulations to protect the health of lead-exposed workers in Malaysia is currently being drafted by the government.
    Matched MeSH terms: Lead Poisoning/etiology*
  3. Chong CK, Senan P, Kumar GV
    Med J Malaysia, 1997 Jun;52(2):169-71.
    PMID: 10968076
    Two cases of carbon monoxide poisoning involving 3 victims occurred in Cameron Highlands in the months of August and September 1995. Two of the victims were found dead in the bathrooms where they were taking a bath while the other one survived. Blood toxicology from the post mortems revealed high levels of carbon monoxide. The only significant source of carbon monoxide in both cases were the gas water heaters which were installed in the bathrooms. A multigas detector was used to monitor the level of carbon monoxide in one of the bathrooms and carbon monoxide was found to be produced to 1200 ppm in 16 minutes during operation of the heater. Carbon monoxide poisoning from gas water heaters installed in bathroom is a significant hazard.
    Matched MeSH terms: Carbon Monoxide Poisoning/etiology*
  4. Nasir HM, Kassim MS, Malinee T, Khairul AM, Low BH
    Med J Malaysia, 1993 Sep;48(3):361-3.
    PMID: 8183154
    We report here a case of lead poisoning in a 20 month old girl who presented with acute encephalopathy and status epilepticus. The major clues leading to the diagnosis were the occupational family history and dense lead lines on X-ray of the long bones. She showed evidence of neurological dysfunction in the initial phase, but she improved steadily, regaining her motor power partially and her vision, although some cognitive and language deficits were already evident. She will need long-term neurological assessment and evaluation to ascertain the extent of permanent brain damage.
    Matched MeSH terms: Lead Poisoning/etiology
  5. Supramaniam V, Mohanadas R
    Med J Malaysia, 1980 Sep;35(1):28-30.
    PMID: 7253994
    Two outbreaks of mushrooms poisoning involving 3 and 9 soldiers respectively with one death on 9 March 1980 in Perak are described. The symptoms were compatible with muscarine [a neurotoxin] poisoning which was detected in the stomach contents of the dead soldier and the mushrooms consumed by one group.
    Matched MeSH terms: Mushroom Poisoning/etiology
  6. Gururaj AK, Khare CB
    Med J Malaysia, 1987 Mar;42(1):68-9.
    PMID: 3431506
    An unusual case of accidental poisoning with Dhatura seeds {sp. Datura stramonium; Syn: Thorn apple) is reported. Its clinical features are essentially due to its peripheral anticholinergic actions and are briefly discussed.
    Matched MeSH terms: Plant Poisoning/etiology*
  7. Arumugaswamy RK, Ali GR, ab Hamid SN
    Lancet, 1993 Jul 24;342(8865):247.
    PMID: 8100972
    Matched MeSH terms: Salmonella Food Poisoning/etiology
  8. Azizi BH, Zulkifli HI, Kassim MS
    Med J Malaysia, 1994 Jun;49(2):132-7.
    PMID: 8090091
    Circumstances surrounding accidental ingestion of poisons were investigated in families of 70 hospitalised children. Indian children were more likely to be hospitalised for poisoning. Poor safety measures directly contributed to poisoning incidents. Poisons had not been stored safely and only in 12.9 per cent of families were the poisons allegedly kept in cupboards. Kerosene had been ingested from soft drink containers in 70 per cent of instances. Medications had been taken mainly from plastic envelopes (57.9%) or bottles (31.6%). Safety practices in the homes of cases and 140 controls were compared. As a whole parents of victims had poor safety practices when compared with parents of controls. Poisoning incidents were discovered by mothers in 75.0 per cent of the cases. Vomiting was induced by parents in 32.3 per cent of cases involving medications and non-volatile items, and in 41.6 per cent of kerosene ingestions. Before hospitalisation 59.4 per cent were brought to general practitioners and 22.7 per cent to government clinics. Mothers were the main attendants when children were brought for medical care. This study highlights the need for measures to prevent childhood poisoning and reduce its morbidity. Household products and medications should be made safer to children through improved packaging, prescribing instructions and education. Safety and first aid education may be directed towards parents, particularly mothers, through the media and health facilities.
    Matched MeSH terms: Poisoning/etiology*
  9. Ariffin WA, Choo KE, Karnaneedi S
    Med J Malaysia, 1992 Sep;47(3):231-4.
    PMID: 1491651
    Three sisters with cassava poisoning are described. A review of the toxic properties of cassava is presented together with discussion on the methods of its preparation, its adverse effects on man, its detoxification in the body, and the treatment of its poisoning.
    Matched MeSH terms: Plant Poisoning/etiology
  10. Abdullah AS, Lajis NH, Bremner JB, Davies NW, Mustapha W, Rajion MA
    Vet Hum Toxicol, 1992 Apr;34(2):154-5.
    PMID: 1509678
    Spectroscopic examinations of purified extracts of the rumen content of sheep intoxicated by Brachiaria decumbens revealed the presence of a mixture of sapogenins, identified as 3-spirostanols. These isomeric steroid sapogenins (C27H44O3) are believed the toxic principles in causing toxicity in sheep after feeding on B. decumbens.
    Matched MeSH terms: Plant Poisoning/etiology
  11. Chung WM, Chian YY, Azmir A
    Med J Malaysia, 2018 12;73(6):453-454.
    PMID: 30647232
    Datura plants contain anticholinergic properties. Consumers may present with a spectrum of anticholinergic symptoms, including hallucination, agitation, tachycardia, delirium, hyperthermia, and dilated pupils. Prompt identification of the symptoms with appropriate treatment can be life-saving. Some patients might not be able to provide history and therefore recognition of toxidromes is imperative. Awareness should be built among the public who may be exposed to such fruits or plants.
    Matched MeSH terms: Plant Poisoning/etiology
  12. Ang HH, Lee EL, Matsumoto K
    Hum Exp Toxicol, 2003 Aug;22(8):445-51.
    PMID: 12948085 DOI: 10.1191/0960327103ht382oa
    In Malaysia, the phase 3 registration for traditional medicines was implemented on 1 January 1992 under the Control of Drugs and Cosmetics Regulation 1984, emphasizing quality, efficacy and safety (including the detection of the presence of heavy metals) in all pharmaceutical dosage forms of traditional medicine preparations. Therefore, a total of 100 products in various pharmaceutical dosage forms of a herbal preparation, were analysed for lead content using atomic absorption spectrophotometer. Results showed that 8% (eight products) possessed 10.64-20.72 ppm of lead, and therefore, do not comply with the quality requirement for traditional medicines in Malaysia. One of these products, M-Tongkat Ali (exhibited 10.64 +/-0.37 ppm of lead), was in fact already registered with the DCA Malaysia. The rest, Sukarno Tongkat Ali, Eurycoma Madu, Super Pill Tongkat Ali, Force Pill Tongkat Ali, Tender Pill Tongkat Ali, Super Pill Tongkat Ali Plus and Great Pill Tongkat Ali Plus have not registered with the DCA Malaysia and exhibited 12.24-20.72 ppm of lead. Although this study showed that only 92% of the products complied with the quality requirement for traditional medicines in Malaysia, however, they cannot be assumed safe from lead contamination because of batch-to-batch inconsistency.
    Matched MeSH terms: Lead Poisoning/etiology
  13. Chang SS, Chen YY, Yip PS, Lee WJ, Hagihara A, Gunnell D
    PLoS Med, 2014 Apr;11(4):e1001622.
    PMID: 24691071 DOI: 10.1371/journal.pmed.1001622
    BACKGROUND: Suicides by carbon monoxide poisoning resulting from burning barbecue charcoal reached epidemic levels in Hong Kong and Taiwan within 5 y of the first reported cases in the early 2000s. The objectives of this analysis were to investigate (i) time trends and regional patterns of charcoal-burning suicide throughout East/Southeast Asia during the time period 1995-2011 and (ii) whether any rises in use of this method were associated with increases in overall suicide rates. Sex- and age-specific trends over time were also examined to identify the demographic groups showing the greatest increases in charcoal-burning suicide rates across different countries.

    METHODS AND FINDINGS: We used data on suicides by gases other than domestic gas for Hong Kong, Japan, the Republic of Korea, Taiwan, and Singapore in the years 1995/1996-2011. Similar data for Malaysia, the Philippines, and Thailand were also extracted but were incomplete. Graphical and joinpoint regression analyses were used to examine time trends in suicide, and negative binomial regression analysis to study sex- and age-specific patterns. In 1995/1996, charcoal-burning suicides accounted for <1% of all suicides in all study countries, except in Japan (5%), but they increased to account for 13%, 24%, 10%, 7%, and 5% of all suicides in Hong Kong, Taiwan, Japan, the Republic of Korea, and Singapore, respectively, in 2011. Rises were first seen in Hong Kong after 1998 (95% CI 1997-1999), followed by Singapore in 1999 (95% CI 1998-2001), Taiwan in 2000 (95% CI 1999-2001), Japan in 2002 (95% CI 1999-2003), and the Republic of Korea in 2007 (95% CI 2006-2008). No marked increases were seen in Malaysia, the Philippines, or Thailand. There was some evidence that charcoal-burning suicides were associated with an increase in overall suicide rates in Hong Kong, Taiwan, and Japan (for females), but not in Japan (for males), the Republic of Korea, and Singapore. Rates of change in charcoal-burning suicide rate did not differ by sex/age group in Taiwan and Hong Kong but appeared to be greatest in people aged 15-24 y in Japan and people aged 25-64 y in the Republic of Korea. The lack of specific codes for charcoal-burning suicide in the International Classification of Diseases and variations in coding practice in different countries are potential limitations of this study.

    CONCLUSIONS: Charcoal-burning suicides increased markedly in some East/Southeast Asian countries (Hong Kong, Taiwan, Japan, the Republic of Korea, and Singapore) in the first decade of the 21st century, but such rises were not experienced by all countries in the region. In countries with a rise in charcoal-burning suicide rates, the timing, scale, and sex/age pattern of increases varied by country. Factors underlying these variations require further investigation, but may include differences in culture or in media portrayals of the method. Please see later in the article for the Editors' Summary.

    Matched MeSH terms: Carbon Monoxide Poisoning/etiology
  14. Abdullah AS, Noordin MM, Rajion MA
    Vet Hum Toxicol, 1989 Apr;31(2):128-9.
    PMID: 2929118
    Severe neurological dysfunction was observed in sheep 4 weeks after grazing on Signal grass (Brachiaria decumbens). These neurological disorders included the stamping of forelegs, star-gazing, incoordination, head-pressing against the fence and circling movements. Histologically, numerous vacuolations of various sizes were observed in the white matter of the brain giving rise to a spongy appearance.
    Matched MeSH terms: Plant Poisoning/etiology
  15. Hor SY, Ahmad M, Farsi E, Lim CP, Asmawi MZ, Yam MF
    J Ethnopharmacol, 2011 Oct 11;137(3):1067-76.
    PMID: 21767625 DOI: 10.1016/j.jep.2011.07.007
    Coriolus versicolor, which is known as Yun Zhi, is one of the commonly used Chinese medicinal herbs. Recent studies have demonstrated its antitumor activities on cancer cells which led to its widespread use in cancer patient. However, little toxicological information is available regarding its safety. The present study evaluated the potential toxicity of Coriolus versicolor standardized water extract after acute and subchronic administration in rats.
    Matched MeSH terms: Mushroom Poisoning/etiology*
  16. Zhang SS, Noordin MM, Rahman SO, Haron MJ
    Vet Hum Toxicol, 2001 Apr;43(2):83-7.
    PMID: 11308125
    An attempt was made to clarify the association between zinc (Zn) and antioxidants due to Zn supplementation on lipid peroxidation occurring during Brachiaria decumbens intoxication. The concentration of Zn, copper, malondialdehyde (MDA), superoxide dismutase (SOD), and gluthathione peroxidase (GSH-Px) were determined in tissues. There was a gradual increment in the concentration of Zn and MDA in serum and hepatocytic SOD in groups given Zn + B decumbens. A decline in erythrocytic GSH-Px and SOD, and lower concentration of reduced glutathione in hepatocyte cytosols were also detected in these sheep. It is highly suggestive that Zn supplementation may depress antioxidant status and enhance lipid peroxidation during B decumbens intoxication.
    Matched MeSH terms: Plant Poisoning/etiology
  17. West CE, Perrin DD, Shaw DC, Heap GH, Soemanto
    PMID: 4274568
    Matched MeSH terms: Plant Poisoning/etiology*
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