Browse publications by year: 2005

  1. Azhar MZ
    Med J Malaysia, 2005 Aug;60 Suppl D:24-7.
    PMID: 16315619
    Medical schools have existed in Malaysia for a very long time. The majority of practicing doctors has trained locally. From the early nineteen sixties when the first medical school was established to the current 7 public medical faculties, the standards of local trained doctors have always been exemplary. Now with more need for doctors to serve the country and the mushrooming of medical schools, the question of needs and wants of future medical schools and medical education need to be addressed. In this paper I will try to highlight what we in Universiti Putra Malaysia have been working on to improve the Medical and Health Sciences faculty to achieve greater heights to reach the future in the shortest possible time.
    MeSH terms: Curriculum/standards; Education, Medical/organization & administration; Education, Medical/standards*; Education, Medical/trends; Forecasting; Humans; Malaysia; Organizational Objectives; School Admission Criteria; Schools, Medical/organization & administration; Schools, Medical/standards*
  2. Mahmud Mohd MN
    Med J Malaysia, 2005 Aug;60 Suppl D:28-31.
    PMID: 16315620
    The Malaysian Medical Council (MMC) operates under the Medical Act of 1971, which defines its core functions related to (a) the registration and practice of medical practitioners (b) the period of compulsory service (c) provisions to be enacted for purposes of (a) and (b). In the early years the MMC used the list of recognised colleges or Universities that appeared in the list of degrees recognised by the General Medical Council of United Kingdom (GMC). Over the years the MMC has undertaken the role of granting recognition to other medical schools in the country and overseas, and added the name of these schools to the existing register of recognised medical degrees in the second schedule of the Act. For the purpose of recognition of medical schools the MMC endorsed a guideline on standards and procedures on accreditation developed in 1996, which was later realigned with international and regional guidelines, in 2000 and 2001. It is recommended that the MMC establishes an active functional 'Education Committee' and that the role of MMC in medical education should be clearly and explicitly stated in the Act. An amendment to the Act would require the MMC to be responsible not only for undergraduate medical education but medical education in its entire phase.
    MeSH terms: Education, Medical/organization & administration; Education, Medical/standards*; Humans; Licensure, Medical*; Malaysia; Registries; Schools, Medical/organization & administration; Schools, Medical/standards*; Social Responsibility; Specialty Boards/legislation & jurisprudence*; Specialty Boards/organization & administration; Professional Role
  3. Mahmud MN
    Med J Malaysia, 2005 Aug;60 Suppl D:32-4.
    PMID: 16315621
    Members of the medical profession are expected to be well aware and abide by the revised code of ethics adopted by the Malaysian Medical Council on 9th December 1986. Under the Act Council may, in the exercise of its disciplinary jurisdiction, impose punishments related to misconduct or malpractices. When a complaint or information is made against any practitioner, the President shall forward such complaint to the Chairman of the Preliminary Investigation Committee. The procedure of the disciplinary inquiry is not exactly like those in the court of law but the same principle of justice is adhered to and all evidence used to make a decision must only be those that are admissible in accordance with the rule of evidence.
    MeSH terms: Employee Discipline; Ethics, Medical*; Humans; Licensure, Medical; Malaysia; Specialty Boards/organization & administration*; Peer Review, Health Care/methods; Professional Misconduct*; Codes of Ethics
  4. Azila NM, Tan CP
    Med J Malaysia, 2005 Aug;60 Suppl D:35-40.
    PMID: 16315622
    Accreditation is a process by which official accrediting bodies evaluate institutions using a set of criteria and standards, following established procedures, to ensure a high quality of education needed to produce highly competent graduates. Additional objectives include (1) ensuring quality institutional functioning, (2) strengthening capabilities of educational institutions for service to the nation and (3) improving public confidence in medical schools. The accreditation process provides an opportunity for the institution to critically reflect upon all the aspects of its programme and the level of compliance or attainment of the requirements. The self-evaluation exercise, which identifies strengths and weaknesses, is perceived as formative. It is envisaged that eventually institutions will adopt a learning culture for curriculum development, implementation, monitoring and matching the outcomes. In conclusion, periodic accreditation activities can act as a "monitoring" system to ensure that the quality of medical education is maintained according to established standards.
    MeSH terms: Accreditation/methods; Accreditation/standards*; Decision Making, Organizational; Developing Countries; Education, Medical/standards*; Humans; Malaysia; Schools, Medical/standards*; Guidelines as Topic; Total Quality Management; Developed Countries; Internationality
  5. Sim SM, Achike FI, Geh SL
    Med J Malaysia, 2005 Aug;60 Suppl D:41-7.
    PMID: 16315623
    In Malaysia many new medical schools (both public and private) have been set up in the last 12 years. As a result of global changes and local adjustments made in medical training, cross-breeds of different medical curricula have produced a wide spectrum of teaching-learning methods in these medical schools. In this paper, we have selected three medical schools--two public (Universiti Malaya and Universiti Putra Malaysia) and one private (International Medical University) to illustrate different approaches in the teaching-learning of pharmacology that exist in Malaysia. How do these different teaching-learning approaches affect the students' interest and ability to "master" pharmacology and in turn to develop a good prescribing practice?
    MeSH terms: Competency-Based Education; Curriculum*; Education, Medical/methods*; Education, Pharmacy/methods*; Faculty, Medical; Humans; Learning*; Malaysia; Pharmacology, Clinical/education*; Schools, Medical; Teaching/methods; Private Sector; Public Sector
  6. Tan CP, Rokiah P
    Med J Malaysia, 2005 Aug;60 Suppl D:48-53.
    PMID: 16315624
    Formative and summative student assessment has always been of concern to medical teachers, and this is especially important at the level of graduating doctors. The effectiveness and comprehensiveness of the clinical training provided is tested with the use of clinical cases, either with real patients who have genuine medical conditions, or with the use of standardised patients who are trained to simulate accurately actual patients. The Objective Structured Clinical Examination (OSCE) is one method of assessing the adequacy of clinical skills of medical students, and their level of competence. It can be used to test a variety of skills such as history taking (communication and interpersonal skills) and performing aspects of physical examination, undertaking emergency procedures, and interpreting investigational data. It can also be used to ensure an adequate depth and breadth of coverage of clinical skills expected of a graduating doctor.
    MeSH terms: Clinical Competence*; Curriculum; Education, Medical/standards*; Educational Measurement/methods*; Humans; Malaysia; Schools, Medical/standards*; Specialization
  7. Mohd Sidik S, Azhar MZ, Mohd Yunus A, Azlan Hamzah SA
    Med J Malaysia, 2005 Aug;60 Suppl D:54-7.
    PMID: 16315625
    The Community Follow-up Project (CFUP) is a project where medical students choose a hospital in-ward patient during their clinical ward-based attachments and follow-up this patient's progress after discharge from the hospital. The students do a series of home visits and also accompany their patients for some of their follow-ups at the hospital, government clinics, general practitioners' clinics and even to the palliative care or social welfare centres. The students assess the physical, psychological and social impact of the illness on the patient, family and community. By following their patients from the time their patients were in the hospital and back to their homes and community, the students are able to understand in depth the problems faced by patients, the importance of communication skills in educating patients on their illness and the importance of good communication between primary, secondary and tertiary care.
    MeSH terms: Attitude of Health Personnel; Clinical Clerkship/organization & administration*; Community Health Services*; Community Medicine/education*; Continuity of Patient Care*; Gynecology/education; House Calls; Humans; Malaysia; Obstetrics/education; Pediatrics/education; Students, Medical/psychology; Program Evaluation; Program Development; Patient-Centered Care*
  8. Ramasamy P, Osman A
    Med J Malaysia, 2005 Aug;60 Suppl D:58-65.
    PMID: 16315626
    The integrated curriculum at the newly established medical school at University Malaysia Sabah is examined from aspects of the objectives of the medical training in achieving development of the required skills and knowledge as well as personal and professional development. The teaching is spread over five years with an emphasis on basic medical sciences in the first two years although the students are exposed to clinical skills right from the onset. A gradual transition to emphasis on the acquisition of clinical skills occurs from the third year onwards. However, community medicine and professional development are incorporated into the programme from the first year and are carried over to the final year. Although there are examinations to be passed in all the courses taught every semester, with a Cumulative Grade Point Average (CGPA) of 3.0 (65 percentile score) and the candidate has to pass all the examinations in that year to clear a particular year, two professional examinations are administered, one at the end of the Third Year (end of the Phase I of the Medical Programme) and another at the end of the Fifth or Final year (end of the Phase II of the Medical Programme). Programmes for Postings, Shadow House Officers (SHOP) and Population Health are also incorporated into the curriculum. Delivery of the courses involve Lectures, Self-Learning Packages (SLP), Small Group Discussions (SGD), Seminars, Debates, Dramas, Video clips, Special Study Modules (SSM), Computer-Aided Instruction (CAI), Problem-based Learning (PBL), Problem-solving Sessions (PSS) and Clinical Skills Learning (CSL). The examination involves elements of continuous assessment and final end of semester or end of phases I and II Professional Examinations. Practical may involve Objective Structured Practical Examinations (OSPE) and/or Objective Structured Clinical Examinations (OSCE). They may also involve viva voce and/or short and long case presentations and assessment of log book entries.
    MeSH terms: Clinical Competence; Competency-Based Education; Curriculum*; Education, Medical/methods*; Education, Medical/standards; Humans; Malaysia; Organizational Objectives; Schools, Medical/standards*; Teaching/methods*; Problem-Based Learning
  9. Noor Ghani S, Saimy I
    Med J Malaysia, 2005 Aug;60 Suppl D:66-8.
    PMID: 16315627
    In 1977, the World Health Assembly (WHA) set the social target--the "Health For All" goal and in 1995, urged member states to "re-orientate medical education and medical practice for "Health For All" (resolution WHA 48.8). This led to World Health Organisation to enunciate the "5-star doctor" needing skills in healthcare management, quality assurance and health economics. The Faculty of Medicine, University of Malaya introduced the New Integrated Curriculum (NIC) in 1995. The objective was aimed at producing a competent doctor with a holistic approach to the practice of medicine. This was to be achieved by having 3 strands of studies i.e. The Scientific Basis of Medicine (SBM), the Doctor, Patient, Health and Society (DPHS), and Personal and Professional Development (PPD) over the 5-year programme, split into 3 phases. Elements of the "5-star doctor" were introduced in strand 2--DPHS and strand 3--PPD. Management studies were introduced in the Personal and Professional Development (PPD) strand. This led to an instructional module--"Principles of Management in Health Care Services (PMGT)" comprising of the Management of Self, Resources and People and incorporating a three week field programme. Evaluation is undertaken at the end of the phase IIIA of the studies. This NIC approach will be able to produce a "5-star doctor", a team player, leader, communicator and an effective manager.
    MeSH terms: Competency-Based Education; Curriculum/standards*; Education, Medical/standards*; Health Services Administration*; Humans; Leadership; Malaysia; Patient Care Team; Personnel Management; Professional Competence; World Health Organization; Healthy People Programs
  10. Harwant S, Pravin D, Teng EM
    Med J Malaysia, 2005 Aug;60 Suppl D:69-70.
    PMID: 16315628
    MeSH terms: Clinical Competence*; Competency-Based Education; Curriculum/standards*; Education, Medical, Undergraduate/standards*; Educational Measurement*; Hospital Departments/standards; Humans; Malaysia; Orthopedics/education*
  11. Severyanova L, Lazarev A
    Med J Malaysia, 2005 Aug;60 Suppl D:71-4.
    PMID: 16315629
    The Russian Federation of higher medical institutions get State accreditation, if their activity conforms to criteria determined by the Ministry of Public Health and the Ministry of Education of the Russian Federation. Kursk State Medical University (KSMU) has a confirmed to requirement of accreditation by the Russian Federation, to conduct annually training of about 5000 students at 12 faculties. KSMU carries out pre-medical undergraduate and postgraduate training in the specialty "Doctor of medicine". For the first time in Russia KSMU was allowed to conduct a 6-year medical training with the use of English as an intermediary language by the Ministry of Public Health and the Ministry of Education. In this relation programmes of training teachers for conducting instruction with the use of an intermediary language (English) and training students Russian with the level necessary for free communication with Russian patients and staff of the clinics have been developed and realized.
    MeSH terms: Accreditation/organization & administration; Accreditation/standards*; Curriculum/standards*; Education, Medical, Graduate/standards*; Education, Medical, Undergraduate/standards*; Faculty, Medical/standards; Humans; Quality Control; Russia; School Admission Criteria; Schools, Medical/standards*; Teaching/methods; Program Development
  12. Raju C
    Med J Malaysia, 2005 Aug;60 Suppl D:75-8.
    PMID: 16315630
    This paper attempts to sensitize the participants to understand the benefits of looking at the regulations of accreditation for medical courses in the neighbouring nearby countries. Deregulation of Medical Education like what they have done will bring enormous revenue benefits for the existing assets like the airports, hospitals, hotels resorts and the communication infrastructure of Malaysia.
    MeSH terms: Accreditation/standards*; Education, Medical/standards*; Foreign Medical Graduates/legislation & jurisprudence*; Foreign Medical Graduates/supply & distribution; Humans; India; Licensure, Medical; Organizational Innovation; Physicians/legislation & jurisprudence*; Physicians/supply & distribution; Schools, Medical; Specialty Boards/organization & administration*; Telemedicine; Internet; Internationality
  13. Babanin AA, Kubyshkin AV
    Med J Malaysia, 2005 Aug;60 Suppl D:79-83.
    PMID: 16315631
    The paper presents a general characteristic of the organization of teaching of medicine to foreign students at the Crimean State Medical University. The Crimea State Medical University is a state higher educational establishment having the 4th highest level of state accreditation. The University prepares junior specialists and bachelors in specialties such as nursing, orthopedic dentistry, pharmacy and doctors in general medicine, dentistry and clinical pharmacy. At present there are 1,500 foreign students from 34 countries studying at the university, with more than half are students from Malaysia. The quality of education at CSMU is evaluated by the State accreditation commission an authorized central executive power in the field of education and science. Textbooks and manuals written in English, which have passed expert evaluation at a state level and approved by the Ministry of Public Health of Ukraine, was given permission to be used by all medical schools of the country.
    MeSH terms: Accreditation/organization & administration; Accreditation/standards*; Education, Medical/standards*; Foreign Professional Personnel/education*; Humans; Schools, Medical/standards*; Ukraine; Internationality
  14. Srinivasan V, Maestroni GJ, Cardinali DP, Esquifino AI, Perumal SR, Miller SC
    Immun Ageing, 2005;2:17.
    PMID: 16316470
    Aging is associated with a decline in immune function (immunosenescence), a situation known to correlate with increased incidence of cancer, infectious and degenerative diseases. Innate, cellular and humoral immunity all exhibit increased deterioration with age. A decrease in functional competence of individual natural killer (NK) cells is found with advancing age. Macrophages and granulocytes show functional decline in aging as evidenced by their diminished phagocytic activity and impairment of superoxide generation. There is also marked shift in cytokine profile as age advances, e.g., CD3+ and CD4+ cells decline in number whereas CD8+ cells increase in elderly individuals. A decline in organ specific antibodies occurs causing reduced humoral responsiveness. Circulating melatonin decreases with age and in recent years much interest has been focused on its immunomodulatory effect. Melatonin stimulates the production of progenitor cells for granulocytes-macrophages. It also stimulates the production of NK cells and CD4+ cells and inhibits CD8+ cells. The production and release of various cytokines from NK cells and T-helper lymphocytes also are enhanced by melatonin. Melatonin presumably regulates immune function by acting on the immune-opioid network, by affecting G protein-cAMP signal pathway and by regulating intracellular glutathione levels. Melatonin has the potential therapeutic value to enhance immune function in aged individuals and in patients in an immunocompromised state.
  15. Nurhanan MY, Azimahtol Hawariah LP, Mohd Ilham A, Mohd Shukri MA
    Phytother Res, 2005 Nov;19(11):994-6.
    PMID: 16317660 DOI: 10.1002/ptr.1759
    The methanol, n-butanol, chloroform and water extracts obtained from the root of Eurycoma longifolia Jack were assayed using methylene blue assay to evaluate its cytotoxic effect against KB, DU-145, RD, MCF-7, CaOV-3, MDBK cell lines. The results showed that all the root extracts except the water extract of E. longifolia produced significant cytotoxic effect on these cell lines. However, no significant cytotoxic effect was detected on MDBK (kidney) normal cell line. 9-methoxycanthin-6-one, an alkaloid, was detected in each extract with different intensities by reversed-phase high performance liquid chromatography.
    MeSH terms: Carbolines/analysis; Carbolines/toxicity; Humans; Methylene Blue; Plant Extracts/toxicity*; Plant Roots/chemistry; Eurycoma*; Cell Line, Tumor/drug effects*
  16. Shamel MM, Azaha RB, Al-Zuhair S
    PMID: 16317961
    The amount of lipase from Mucor miehei adsorption on ultrafiltration polysulfone hollow fiber membrane chips has been determined using different lipase concentrations at three different temperatures, namely 30, 35, and 40 degrees C. It was experimentally shown that adsorption of lipase increases with temperature. The results were used to evaluate the constants found in the Langmuir adsorption isotherm model coupled with the Van't Hoff's relationship. A temperature dependence correlation for the amount of adsorbed lipase activity, alip,ads, and that present in the supernatant solution, alip,free was determined. The effect of varying the concentration on a cross-linking agent, namely, glutaraldehyde, to the membrane chips was also tested. It was found that, under the same operating conditions, the amount of lipase adsorbed on polysulfone membranes was increased dramatically after pre-treating the membrane with 1% Glutaraldehyde. However, increasing the concentration of the cross-linking agent has a low effect on the amount of lipase adsorbed.
    MeSH terms: Adsorption; Cross-Linking Reagents; Glutaral; Membranes, Artificial*; Mucor/enzymology; Temperature; Ultrafiltration/instrumentation
  17. Alam MZ, Mahmat ME, Muhammad N
    PMID: 16317964
    A laboratory-scale study of bioconversion of local lignocellulosic material, oil palm biomass (OPB) was conducted by evaluating the enzyme production through microbial treatment in solid state bioconversion (SSB). OPB in the form of empty fruit bunches (EFB) was used as a solid substrate and treated with the white-rot fungus, Phanerochaete chrysosporium, to produce ligninase. The results showed that the highest ligninase activity of 400.27 U/liter was obtained at day 12 of fermentation. While the optimum study indicated the enzyme production of 1472.8 U/liter with moisture content of 50%, 578.7 U/liter with 10% v/w of inoculum size, and 721.8 U/liter with co-substrate concentration of 1% (w/w) at days 9, 9 and 12 of fungal treatment, respectively. The parameters glucosamine and reducing sugar were observed to evaluate the growth and substrate utilization in the experiment.
    MeSH terms: Biotransformation; Cellulose/metabolism; Fermentation; Lignin/metabolism; Oxygenases/biosynthesis*; Plant Oils/metabolism*; Biomass*; Phanerochaete/enzymology; Phanerochaete/growth & development
  18. Harcourt BH, Lowe L, Tamin A, Liu X, Bankamp B, Bowden N, et al.
    Emerg Infect Dis, 2005 Oct;11(10):1594-7.
    PMID: 16318702
    Until 2004, identification of Nipah virus (NV)-like outbreaks in Bangladesh was based on serology. We describe the genetic characterization of a new strain of NV isolated during outbreaks in Bangladesh (NV-B) in 2004, which confirms that NV was the etiologic agent responsible for these outbreaks.
    MeSH terms: Animals; Bangladesh/epidemiology; Base Sequence; Cloning, Molecular; Disease Outbreaks*; Humans; Malaysia; Molecular Sequence Data; Phylogeny; Viral Proteins/genetics; Sequence Analysis, DNA; DNA, Complementary/genetics; Reverse Transcriptase Polymerase Chain Reaction; Nipah Virus/classification*; Nipah Virus/genetics*; Nipah Virus/isolation & purification; Henipavirus Infections/epidemiology*; Henipavirus Infections/virology*
  19. Volkov I, Banavar JR, He F, Hubbell SP, Maritan A
    Nature, 2005 Dec 1;438(7068):658-61.
    PMID: 16319890
    The recurrent patterns in the commonness and rarity of species in ecological communities--the relative species abundance--have puzzled ecologists for more than half a century. Here we show that the framework of the current neutral theory in ecology can easily be generalized to incorporate symmetric density dependence. We can calculate precisely the strength of the rare-species advantage that is needed to explain a given RSA distribution. Previously, we demonstrated that a mechanism of dispersal limitation also fits RSA data well. Here we compare fits of the dispersal and density-dependence mechanisms for empirical RSA data on tree species in six New and Old World tropical forests and show that both mechanisms offer sufficient and independent explanations. We suggest that RSA data cannot by themselves be used to discriminate among these explanations of RSA patterns--empirical studies will be required to determine whether RSA patterns are due to one or the other mechanism, or to some combination of both.
    MeSH terms: Cameroon; Ecuador; Malaysia; Models, Biological*; Panama; Sri Lanka; Trees/growth & development; Trees/physiology*; Tropical Climate*; Biomass; Biodiversity*
  20. Batra YK, Ivanova M, Ali SS, Shamsah M, Al Qattan AR, Belani KG
    Paediatr Anaesth, 2005 Dec;15(12):1094-7.
    PMID: 16324030 DOI: 10.1111/j.1460-9592.2005.01633.x
    BACKGROUND: Laryngospasm is a well-known problem typically occurring immediately following tracheal extubation. Propofol is known to inhibit airway reflexes. In this study, we sought to assess whether the empiric use of a subhypnotic dose of propofol prior to emergence will decrease the occurrence of laryngospasm following extubation in children.
    METHODS: After approval from the Institutional Ethics Committee and informed parental consent, we enrolled 120 children ASA physical status I and II, aged 3-14 years who were scheduled to undergo elective tonsillectomy with or without adenoidectomy under standard general anesthesia. Before extubation, the patients were randomized and received in a blinded fashion either propofol 0.5 mg.kg(-1) or saline (control) intravenously. Tracheal extubation was performed 60 s after administration of study drug, when the child was breathing regularly and reacting to the tracheal tube.
    RESULTS: Laryngospasm was seen in 20% (n = 12) of the 60 children in the control group and in only 6.6% (n = 4) of 60 children in the propofol group (P < 0.05).
    CONCLUSIONS: During emergence from inhalational anesthesia, propofol in a subhypnotic dose (0.5 mg.kg(-1)) decreases the likelihood of laryngospasm upon tracheal extubation in children undergoing tonsillectomy with or without adenoidectomy.
    MeSH terms: Adenoidectomy*; Adolescent; Anesthesia, General; Child; Child, Preschool; Double-Blind Method; Humans; Hypnotics and Sedatives/administration & dosage*; Intubation, Intratracheal; Laryngismus/etiology; Laryngismus/prevention & control*; Postoperative Complications/prevention & control*; Tonsillectomy*; Propofol/administration & dosage*; Device Removal
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