Browse publications by year: 2015

  1. Leung J, Lopez A, Mitchell T, Weinberg M, Lee D, Thieme M, et al.
    J Immigr Minor Health, 2015 Feb;17(1):310-3.
    PMID: 24271111 DOI: 10.1007/s10903-013-9946-x
    Little is known about varicella-zoster virus (VZV) susceptibility in US-bound refugee populations, although published data suggest that VZV seroprevalence in these refugee populations may be lower than US populations. We describe VZV seroprevalence in five US-bound refugee groups: (1) Bhutanese in Nepal, (2) Burmese on the Thailand-Burma (Myanmar) border, (3) Burmese in Malaysia, (4) Iraqi in Jordan, and (5) Somali in Kenya. Sera were tested for presence of VZV IgG antibodies among adults aged 18-45 years. Overall VZV seroprevalence was 97% across all refugee groups. VZV seroprevalence was also high across all age groups, with seroprevalence ranging from 92-100% for 18-26 year-olds depending on refugee group and 93-100% for 27-45 year-olds. VZV seroprevalence was unexpectedly high in these five US-bound refugee groups, though may not reflect seroprevalence in other refugee groups. Additional studies are needed to better understand VZV seroprevalence in refugee populations over time and by region.
    MeSH terms: Adolescent; Adult; Bhutan/ethnology; Myanmar/ethnology; Chickenpox/ethnology*; Chickenpox/epidemiology; Enzyme-Linked Immunosorbent Assay; Female; Humans; Iraq/ethnology; Male; Middle Aged; Nepal/ethnology; Refugees; Somalia/ethnology; Herpesvirus 3, Human/isolation & purification*; Seroepidemiologic Studies
  2. Moy FM, Darus A, Hairi NN
    Asia Pac J Public Health, 2015 Mar;27(2):176-84.
    PMID: 24285778 DOI: 10.1177/1010539513510555
    Handgrip strength is useful for screening the nutritional status of adult population as it is strongly associated with physical disabilities and mortality. Therefore, we aimed to determine the predictors of handgrip strength among adults of a rural community in Malaysia using a cross-sectional study design with multistage sampling. All adults aged 30 years and older from 1250 households were invited to our study. Structured questionnaire on sociodemographic characteristics, medical history, occupation history, lifestyle practices, and measurements, including anthropometry and handgrip strength were taken. There were 2199 respondents with 55.2% females and majority were of Malay ethnicity. Their mean (standard deviation) age was 53.4 (13.2) years. The response rate for handgrip strength was 94.2%. Females had significantly lower handgrip strength than males (P < .05). In the multiple linear regression models, significant predictors of handgrip strength for males were age, height, job groups, and diabetes, while for females, the significant predictors were age, weight, height, and diabetes.
    MeSH terms: Adult; Age Factors; Aged; Aged, 80 and over; Body Weights and Measures; Cross-Sectional Studies; Female; Humans; Life Style; Malaysia; Male; Middle Aged; Nutritional Status; Surveys and Questionnaires; Rural Population*; Sex Factors; Socioeconomic Factors; Linear Models; Hand Strength*
  3. Foo KY
    Int J Inj Contr Saf Promot, 2015;22(2):127-35.
    PMID: 24328944 DOI: 10.1080/17457300.2013.855795
    Driving is a functional task that requires a complex interaction of visual perception, cognitive and motor skills. Next to circulatory diseases and cancer, road accidents remain the third epidemic cause of death internationally, with approximately half a million teen drivers killed annually. Driver behaviour has been cited as the pervasive marker of automotive crashes. A reliable and firm relationship between the positive parental model, message, and communication has been established. Specifically, the familial climate is proposed to be an important element of reinforcement, modelling, support and environmental determinant in interpreting personal perceptions, habits, values, and belief system. Confirming the assertion, this bibliographic review presents the most recent research findings on the contributions of families to the driving habits of teens. The emphasis is speculated on parental alcohol use, aggressiveness, attention-deficit/hyperactivity disorder, relationship, and intergenerational transmission of driving styles. Besides, the effects of familial supervision, monitoring, education and awareness, and genders, partners, and demographic influence on the driving habits are discussed and outlined.
    MeSH terms: Adolescent; Adolescent Behavior*; Aggression; Alcohol Drinking; Attention Deficit Disorder with Hyperactivity/psychology; Automobile Driving/education; Automobile Driving/psychology*; Humans; Parent-Child Relations*; Parents/psychology; Intergenerational Relations
  4. Nikmat AW, Hawthorne G, Al-Mashoor SH
    Dementia (London), 2015 Jan;14(1):114-25.
    PMID: 24339093 DOI: 10.1177/1471301213494509
    Living arrangements play an important role in determining the quality of life (QoL) of people with dementia. Although informal care (home-based) is favored, the transition to formal (institutional) care often becomes necessary, especially in the later stages of dementia. Nevertheless, there is currently no definitive evidence showing that informal or formal care provides a higher QoL for those with dementia.
    MeSH terms: Activities of Daily Living/psychology*; Aged; Aged, 80 and over; Cross-Sectional Studies; Dementia/psychology*; Female; Home Care Services*; Humans; Male; Middle Aged; Neuropsychological Tests; Nursing Homes*; Quality of Life*; Social Behavior
  5. Kamal SM, Hassan CH, Salikon RH
    Asia Pac J Public Health, 2015 Mar;27(2):NP2410-22.
    PMID: 24345848 DOI: 10.1177/1010539513510554
    This study examines safer sex negotiation and its association with condom use among clients of female sex workers (FSWs) in Bangladesh. Data were collected from 484 FSWs living in Dhaka city following a convenient sampling procedure. Overall, 47% of the clients were suggested to use condom during last sexual intercourse and 21% did so. Both bivariate and multivariable binary logistic regression analyses yielded significantly increased risk of negotiation for safer sex with clients among FSWs with higher education. The power bargaining significantly (P < .001) increased the risk of condom use by 2.15 times (95% confidence interval = 1.28-3.59). The odds of condom use were significantly higher among the FSWs with higher education, unmarried, hotel-based, and among those with higher level of HIV/AIDS-related knowledge. The Bangladeshi FSWs have little control over their profession. HIV prevention programs should aim to encourage FSWs through information, education, and communication program to insist on condom use among clients.
    MeSH terms: Adult; Bangladesh; Communication; Cross-Sectional Studies; Female; Humans; Middle Aged; Surveys and Questionnaires; Sexual Partners; HIV Infections/prevention & control; Negotiating*; Condoms/utilization*; Safe Sex*; Sex Workers*
  6. Soon CF, Tee KS, Youseffi M, Denyer MC
    Biosensors (Basel), 2015 Mar;5(1):13-24.
    PMID: 25808839 DOI: 10.3390/bios5010013
    Cell migration is a key contributor to wound repair. This study presents findings indicating that the liquid crystal based cell traction force transducer (LCTFT) system can be used in conjunction with a bespoke cell traction force mapping (CTFM) software to monitor cell/surface traction forces from quiescent state in real time. In this study, time-lapse photo microscopy allowed cell induced deformations in liquid crystal coated substrates to be monitored and analyzed. The results indicated that the system could be used to monitor the generation of cell/surface forces in an initially quiescent cell, as it migrated over the culture substrate, via multiple points of contact between the cell and the surface. Future application of this system is the real-time assaying of the pharmacological effects of cytokines on the mechanics of cell migration.
    MeSH terms: Cell Line; Cell Movement/physiology; Humans; Traction/methods*; Keratinocytes/cytology*; Keratinocytes/chemistry; Liquid Crystals/chemistry*; Mechanical Processes; Time-Lapse Imaging; Single-Cell Analysis/methods*
  7. Nazree NE, Loke AC, Zainal NZ, Mohamed Z
    Asia Pac Psychiatry, 2015 Mar;7(1):72-7.
    PMID: 24376086 DOI: 10.1111/appy.12118
    Numerous association studies of candidate genes studies with major depressive disorder (MDD) have been conducted for many years; however, the evidence of association between genes and the risk of developing MDD still remains inconclusive. In this study, we aimed to investigate the association between the tryptophan hydroxylase 2 (TPH2) gene and MDD in three ethnic groups (Malay, Chinese and Indian) within the Malaysian population.
    MeSH terms: Adolescent; Adult; Depressive Disorder, Major/genetics*; Female; Genotype; Haplotypes; Humans; Malaysia; Male; Middle Aged; Sex Factors; Tryptophan Hydroxylase/genetics*; Linkage Disequilibrium; Genetic Predisposition to Disease; Polymorphism, Single Nucleotide*; European Continental Ancestry Group/genetics; Asian Continental Ancestry Group/genetics; Young Adult; Genetic Association Studies
  8. Low CF, Shamsudin MN, Abdullah M, Chee HY, Aliyu-Paiko M
    J Fish Dis, 2015 Jan;38(1):17-25.
    PMID: 24397626 DOI: 10.1111/jfd.12195
    The mechanisms through which brown-marbled grouper accomplishes resistance to infection, particularly against Vibrios, are not yet fully understood. In this study, brown-marbled grouper fingerlings were experimentally infected with Vibrio parahaemolyticus, to identify disease resistance grouper, and the serum proteome profiles were compared between resistant and susceptible candidates, via two-dimensional gel electrophoresis (2-DE). The results showed that putative parvalbumin beta-2 subunit I, alpha-2-macroglobulin, nattectin and immunoglobulin light chain proteins were among proteins that significantly overexpressed in the resistant fish as compared to the susceptible group of fish, whereas apolipoprotein E and immunoglobulin light chain proteins were observed to be differentially overexpressed in the susceptible fish. Further analysis by peptide sequencing revealed that the immunoglobulin light chain proteins identified in the resistant and susceptible groups differed in amino acid composition. Taken together, the results demonstrated for the first time that putative parvalbumin beta-2 subunit I, alpha-2-macroglobulin, nattectin and immunoglobulin light chain are among important proteins participating to effect disease resistance mechanism in fish and were overexpressed to function collectively to resist V. parahaemolyticus infection. Most of these molecules are mediators of immune response.
    MeSH terms: alpha-Macroglobulins/genetics; Animals; Bass/genetics*; Bass/immunology*; Fish Diseases/physiopathology*; Gene Expression Regulation/immunology*; Immunoglobulin Light Chains/genetics; Parvalbumins/genetics; Vibrio Infections/physiopathology; Vibrio Infections/veterinary*; Vibrio parahaemolyticus/physiology*; Gene Expression Profiling; Fish Proteins/genetics*; Lectins, C-Type/genetics
  9. Mustafa AA, Matinlinna JP, Razak AA, Hussin AS
    J Investig Clin Dent, 2015 Aug;6(3):161-9.
    PMID: 24415731 DOI: 10.1111/jicd.12083
    AIM: To evaluate in vitro the effect of different concentrations of 2-hydroxyethyl methacrylate (HEMA) in experimental silane-based primers on shear bond strength of orthodontic adhesives.

    METHODS: Different volume percentages of HEMA were tested in four experimental silane-based primer solutions (additions of HEMA: 0, 5.0 vol%, 25.0 vol% and 50.0 vol%). An experimental silane blend (primer) of 1.0 vol% 3-isocyanatopropyltrimethoxysilane (ICMS) + 0.5% bis-1,2-(triethoxysilyl) ethane (BTSE) was prepared and used. The experimental primers together with the control group were applied onto acid-etched premolars for attachment of orthodontic brackets. After artificial aging by thermocycling the shear-bond strength was measured. The fractured surfaces of all specimens were examined under scanning electron microscopy (SEM) to evaluate the failure mode on the enamel surface.

    RESULTS: The experimental primers showed the highest shear-bond strength of 21.15 MPa (SD ± 2.70 MPa) and with 25 vol% showed a highly significant increase (P < 0.05) in bond strength. The SEM images showed full penetration of adhesive agents when using silane-based primers. In addition, the SEM images suggested that the predominant failure type was not necessarily the same as for the failure propagation.

    CONCLUSIONS: This preliminary study suggested that nonacidic silane-based primers with HEMA addition might be an alternative to for use as adhesion promoting primers.

    MeSH terms: Acid Etching, Dental/methods; Bicuspid/ultrastructure; Dental Bonding*; Dental Alloys/chemistry; Dental Cements/chemistry*; Humans; Materials Testing; Methacrylates/chemistry*; Microscopy, Electron, Scanning; Silanes/chemistry*; Stress, Mechanical; Surface Properties; Temperature; Time Factors; Orthodontic Brackets*; Isocyanates/chemistry; Shear Strength
  10. Kaur J, Kaur G, Ho BK, Yao WK, Salleh M, Lim KH
    Asia Pac J Public Health, 2015 Apr;27(3):314-22.
    PMID: 24425796 DOI: 10.1177/1010539513517257
    Physical inactivity is the fourth leading risk factor for global mortality. Regular moderate-intensity physical activity has significant benefits for health. To determine the socioeconomic predictors of physical inactivity among elderly Malaysian population. A nationwide community-based survey was conducted among 4831 respondents aged ≥60 years with a face-to-face questionnaire. The prevalence of physical inactivity among the elderly was 88.0%, highest in respondents aged older than 80 years (95.4%), females (90.1%), other Bumiputra (92.2%), earning household income less than RM1000 (87.9%), and residing in urban locality (88.4%). In the multivariate model, the predictors of physical inactivity were only sex, ethnicity, locality, and age group (adjusted odds ratio = 1.3-3.6). The predictors of physical inactivity can identify the risk factors to develop policies that will reduce the public health burden of noncommunicable diseases.
    MeSH terms: Aged; Female; Health Policy; Humans; Malaysia; Male; Middle Aged; Policy Making; Surveys and Questionnaires; Risk Factors; Socioeconomic Factors; Multivariate Analysis; Sedentary Lifestyle*
  11. Nolan D, Stephens F, Crockford M, Jones JB, Snow M
    J Fish Dis, 2015 Feb;38(2):187-95.
    PMID: 24475941 DOI: 10.1111/jfd.12222
    This report documents an emerging trend of identification of Megalocytivirus-like inclusions in a range of ornamental fish species intercepted during quarantine detention at the Australian border. From September 2012 to February 2013, 5 species of fish that had suffered mortality levels in excess of 25% whilst in the post-entry quarantine and had Megalocytivirus-like inclusion bodies in histological sections were examined by PCR. The fish had been imported from Singapore, Malaysia and Sri Lanka. Ninety-seven of 111 individual fish from affected tanks of fish tested were positive for the presence of Megalocytivirus by PCR. Sequence analysis of representative PCR products revealed an identical sequence of 621 bp in all cases which was identical to a previously characterized Megalocytivirus (Sabah/RAA1/2012 strain BMGIV48). Phylogenetic analysis of available Megalocytivirus major capsid protein (MCP) sequences confirmed the existence of 3 major clades of Megalocytivirus. The virus detected in this study was identified as a member of Genotype II. The broad host range and pathogenicity of megalocytiviruses, coupled to the documented spread of ornamental fish into the environment, render this a significant and emerging biosecurity threat to Australia.
    MeSH terms: Animals; Australia; DNA Virus Infections/transmission; DNA Virus Infections/veterinary*; DNA Virus Infections/virology; Fish Diseases/transmission*; Fish Diseases/virology*; Fishes; Iridoviridae/genetics*; Iridoviridae/isolation & purification*; Quarantine; Security Measures; Pets/virology*
  12. Kamal SM, Hassan CH, Alam GM, Ying Y
    J Biosoc Sci, 2015 Jan;47(1):120-39.
    PMID: 24480489 DOI: 10.1017/S0021932013000746
    This study examines the trends and determinants of child marriage among women aged 20-49 in Bangladesh. Data were extracted from the last six nationally representative Demographic and Health Surveys conducted during 1993-2011. Simple cross-tabulation and multivariate binary logistic regression analyses were adopted. According to the survey conducted in 2011, more than 75% of marriages can be categorized as child marriages. This is a decline of 10 percentage points in the prevalence of child marriage compared with the survey conducted in 1993-1994. Despite some improvements in education and other socioeconomic indicators, Bangladeshi society still faces the relentless practice of early marriage. The mean age at first marriage has increased by only 1.4 years over the last one and half decades, from 14.3 years in 1993-1994 to 15.7 years in 2011. Although the situation on risk of child marriage has improved over time, the pace is sluggish. Both the year-of-birth and year-of-marriage cohorts of women suggest that the likelihood of marrying as a child has decreased significantly in recent years. The risk of child marriage was significantly higher when husbands had no formal education or little education, and when the wives were unemployed or unskilled workers. Muslim women living in rural areas have a greater risk of child marriage. Women's education level was the single most significant negative determinant of child marriage. Thus, the variables identified as important determinants of child marriage are: education of women and their husbands, and women's occupation, place of residence and religion. Programmes to help and motivate girls to stay in school will not only reduce early marriage but will also support overall societal development. The rigid enforcement of the legal minimum age at first marriage could be critical in decreasing child marriage.
    MeSH terms: Adolescent; Adult; Age Factors; Bangladesh; Child; Data Collection; Demography/statistics & numerical data; Educational Status; Female; Health Surveys/statistics & numerical data; Humans; Male; Marriage/ethnology*; Marriage/trends; Marriage/statistics & numerical data; Middle Aged; Occupations; Regression Analysis; Religion; Rural Population/trends; Socioeconomic Factors; Young Adult
  13. Dionne KR, Warnakulasuriya S, Zain RB, Cheong SC
    Int J Cancer, 2015 Feb 1;136(3):503-15.
    PMID: 24482244 DOI: 10.1002/ijc.28754
    Despite commendable progress in the prevention, detection, and treatment of a wide variety of solid tumor types, oral squamous cell carcinoma (OSCC) remains a significant health burden across the globe. OSCC carcinogenesis involves accumulation of genetic alterations that coincide with the multistep malignant transformation of normal oral epithelium. OSCC is often first diagnosed at late stages of the disease (advanced regional disease and/or metastasis). Delayed diagnosis precludes successful treatment and favorable outcomes. In clinical practice, opportunities exist to identify patients with oral potentially malignant disorders (OPMDs), which precede the development of cancer. This review addresses the current status of laboratory and clinical research on OPMDs, with emphasis on leukoplakia and erythroplakia. OSF is also presented, though there is a paucity of published studies on this disorder. We focus on findings that could translate into earlier diagnosis and more efficacious treatment of those lesions with significant malignant potential. We explore how markers of OPMD malignant transformation might be implemented into current diagnostic practice to help clinicians objectively stratify patients into treatment/follow-up groups according to relative risk. We provide an overview of recently concluded and ongoing OPMD chemoprevention trials. We describe laboratory OPMD models that can be used to not only to reveal the genetic and molecular intricacies of oral cancer but also to develop novel screening methods and therapeutic approaches. Finally, we call for targeted screening programs of at-risk populations in order to facilitate diagnosis and treatment of OPMD and early OSCC.
    MeSH terms: Aged; Carcinoma, Squamous Cell/diagnosis; Carcinoma, Squamous Cell/etiology; Carcinoma, Squamous Cell/therapy; DNA/analysis; Humans; Leukoplakia, Oral/therapy; Male; Middle Aged; Mouth Neoplasms/diagnosis; Mouth Neoplasms/etiology; Mouth Neoplasms/therapy*; Ploidies; Loss of Heterozygosity; Cyclin D1/genetics
  14. Khonsari S, Subramanian P, Chinna K, Latif LA, Ling LW, Gholami O
    Eur J Cardiovasc Nurs, 2015 Apr;14(2):170-9.
    PMID: 24491349 DOI: 10.1177/1474515114521910
    Medication non-adherence leads to a vast range of negative outcomes in patients with coronary artery disease. An automated web-based system managing short message service (SMS) reminders is a telemedicine approach to optimise adherence among patients who frequently forget to take their medications or miss the timing.
    MeSH terms: Aged; Cardiovascular Agents/therapeutic use*; Female; Humans; Malaysia; Male; Middle Aged; Patient Discharge; Patient Readmission; Reminder Systems*; Acute Coronary Syndrome/drug therapy*; Acute Coronary Syndrome/mortality; Acute Coronary Syndrome/psychology*; Medication Adherence*; Patient Preference; Self Report; Text Messaging*
  15. Liew KB, Tan YT, Peh KK
    Drug Dev Ind Pharm, 2015 Apr;41(4):583-93.
    PMID: 24495273 DOI: 10.3109/03639045.2014.884130
    Manufacturing process and superdisintegrants used in orally disintegrating tablet (ODT) formulation are often time discussed. However, the effect of suitable filler for ODT formulation is not explored thoroughly.
    MeSH terms: Adult; Alzheimer Disease/drug therapy; Alzheimer Disease/economics; Double-Blind Method; Drug Compounding; Drug Stability; Drug Storage; Excipients/administration & dosage*; Excipients/economics; Excipients/chemistry; Hardness; Humans; Indans/administration & dosage*; Indans/adverse effects; Indans/analysis; Indans/economics; Mouth Mucosa/drug effects; Piperidines/administration & dosage*; Piperidines/adverse effects; Piperidines/analysis; Piperidines/economics; Sweetening Agents/administration & dosage*; Sweetening Agents/economics; Sweetening Agents/chemistry; Tablets; Taste; Drug Costs; Nootropic Agents/administration & dosage*; Nootropic Agents/adverse effects; Nootropic Agents/analysis; Nootropic Agents/economics; Glycyrrhizic Acid/administration & dosage*; Glycyrrhizic Acid/economics; Glycyrrhizic Acid/chemistry; Salvia/chemistry; Taste Perception/drug effects; Patient Preference; Drug Liberation
  16. Roehler DR, Ear C, Parker EM, Sem P, Ballesteros MF
    Int J Inj Contr Saf Promot, 2015;22(2):165-71.
    PMID: 24499413 DOI: 10.1080/17457300.2013.876050
    This study examines the risk characteristics of fatal motorcycle crashes in Cambodia over a 5-year period (2007-2011). Secondary data analyses were conducted using the Cambodia Road Crash and Victim Information System, the only comprehensive and integrated road crash surveillance system in the country. Researchers from the Centers for Disease Control and Prevention and Handicap International found that (1) males are dying in motorcycle crashes roughly seven times more frequently than females; (2) motorcyclist fatalities increased by about 30% from 2007 to 2011; (3) the motorcyclist death rates per 100,000 population increased from 7.4 to 8.7 deaths from 2007 to 2011; and (4) speed-related crashes and not wearing motorcycle helmet were commonly reported for motorcyclist fatalities at approximately 50% and over 80% through the study years, respectively. Additionally, this study highlights that Cambodia has the highest motorcycle death rate in South-East Asia, far surpassing Thailand, Malaysia, and Myanmar. By recognising the patterns of fatal motorcycle crashes in Cambodia, local road-safety champions and stakeholders can design targeted interventions and preventative measures to improve road safety among motorcyclists.
    MeSH terms: Accidents, Traffic/mortality*; Accidents, Traffic/trends; Accidents, Traffic/statistics & numerical data; Adolescent; Adult; Cambodia/epidemiology; Child; Child, Preschool; Female; Head Protective Devices/trends; Head Protective Devices/utilization*; Humans; Infant; Infant, Newborn; Male; Middle Aged; Motorcycles/statistics & numerical data*; Incidence; Young Adult; Public Health Surveillance
  17. Liber AC, Ross H, Ratanachena S, Dorotheo EU, Foong K
    Tob Control, 2015 Jun;24(e2):e137-41.
    PMID: 24500266 DOI: 10.1136/tobaccocontrol-2013-051184
    OBJECTIVES: To monitor and analyse impacts of the interaction between tobacco excise tax policy and industry price strategy, on the price level and variation of cigarettes sold in five Southeast Asian countries (Indonesia, Cambodia, Lao PDR, the Philippines and Vietnam).
    METHODS: Prices of cigarette sold by sticks and packs were collected through an in-person survey of retailers during 2011. Mean cigarette prices and price variation were calculated in each study country for single cigarettes, whole packs and brand groups.
    RESULTS: Price variation of whole packs was greater in countries with ad-valorem excise tax structures (Cambodia, Lao PDR and Vietnam) than in countries with multitiered specific excise taxes (Indonesia and the Philippines). The price variation for single sticks appeared to be driven by local currency denomination. Cigarettes sold individually cost more per stick than cigarettes sold in whole packs in every brand group except for Indonesia's domestic brands.
    CONCLUSIONS: Tobacco industry strategy and excise tax structure drove the price level and variation of cigarettes sold in packs, while currency denominations influence the selling price of single sticks. To maximise the effectiveness of tobacco tax policies, countries should adopt specific excise tax structures to decrease cigarette price variation, which would minimise opportunities for smokers to 'trade down' to a cheaper brand to avoid a tax-driven price increase.
    KEYWORDS: Low/Middle Income Country; Packaging and Labelling; Price; Surveillance and Monitoring; Taxation
    MeSH terms: Asia, Southeastern; Commerce*; Costs and Cost Analysis*; Data Collection; Humans; Smoking/economics*; Taxes*; Product Packaging; Tobacco Industry/economics*; Marketing; Policy; Tobacco Products/economics*
  18. Nurliyana AR, Mohd Nasir MT, Zalilah MS, Rohani A
    Public Health Nutr, 2015 Feb;18(2):303-12.
    PMID: 24507623 DOI: 10.1017/S1368980014000068
    OBJECTIVE: The present study aimed to identify dietary patterns and determine the relationship between dietary patterns and cognitive ability among 12- to 13 year-old Malay adolescents in the urban areas of Gombak district in Selangor, Malaysia.

    DESIGN: Data on sociodemographic background were obtained from parents. Height and weight were measured and BMI-for-age was determined. Adolescents were interviewed on their habitual dietary intakes using a semi-quantitative FFQ. Cognitive ability was assessed using the Wechsler Nonverbal Scale of Ability in a one-to-one manner. Dietary patterns were constructed using principal component analysis based on thirty-eight food groups of the semi-quantitative FFQ.

    SETTING: Urban secondary public schools in the district of Gombak in Selangor, Malaysia.

    SUBJECTS: Malay adolescents aged 12 to 13 years (n 416).

    RESULTS: The mean general cognitive ability score was 101·8 (sd 12·4). Four major dietary patterns were identified and labelled as 'refined-grain pattern', 'snack-food pattern', 'plant-based food pattern' and 'high-energy food pattern'. These dietary patterns explained 39·1 % of the variance in the habitual dietary intakes of the adolescents. The refined-grain pattern was negatively associated with processing speed, which is a construct of general cognitive ability. The high-energy food pattern was negatively associated with general cognitive ability, perceptual reasoning and processing speed. Monthly household income and parents' educational attainment were positively associated with all of the cognitive measures. In multivariate analysis, only the high-energy food pattern was found to contribute significantly towards general cognitive ability after controlling for socio-economic status.

    CONCLUSIONS: Consumption of foods in the high-energy food pattern contributed towards general cognitive ability after controlling for socio-economic status. However, the contribution was small.

    MeSH terms: Adolescent; Energy Intake; Child; Child Nutritional Physiological Phenomena/ethnology; Cognition; Cognition Disorders/ethnology; Cognition Disorders/etiology*; Cognition Disorders/prevention & control; Diet/adverse effects*; Diet/ethnology; Female; Humans; Malaysia/epidemiology; Male; Body Mass Index; Prevalence; Nutrition Policy*; Principal Component Analysis; Adolescent Development; Overweight/ethnology; Overweight/etiology; Overweight/epidemiology; Overweight/psychology; Pediatric Obesity/ethnology; Pediatric Obesity/etiology; Pediatric Obesity/epidemiology; Pediatric Obesity/psychology
  19. Hussein AA, Vasudevan R, Patimah I, Prashant N, Nora FA
    Andrologia, 2015 Mar;47(2):168-77.
    PMID: 24528375 DOI: 10.1111/and.12240
    Azoospermia factor region (AZF) deletions (AZFa, AZFb, AZFc and AZFd) in the Y chromosome were analysed in male infertility subjects in various populations with conflicting results. This study comprised of 54 infertile males and 63 fertile controls, and the frequency of AZFa, AZFb, AZFc and AZFd deletions were determined using conventional polymerase chain reaction (PCR) as well as real-time PCR-high resolution melting analysis-based methods. The results of this study showed that, three of 54 cases (5.55%) had AZF (a, b and c) deletions (two had AZFc and one had AZFa deletions). Four cases were found to have AZFd deletions (7.4%) with two of them being associated with AZFc deletions (P = 0.028). The frequency of AZF (a, b and c) deletions in Malaysian infertile male subjects was found to be comparable with other populations. AZFd deletions were found to be significant (P < 0.05) in male infertility and it may be associated with other types of AZF deletions.
    MeSH terms: Adult; Chromosome Deletion*; Genetic Testing; Genotype; Humans; Infertility, Male/ethnology*; Infertility, Male/genetics*; Infertility, Male/epidemiology; Malaysia/epidemiology; Male; Phenotype; Risk Factors; Case-Control Studies; Polymerase Chain Reaction/methods; Chromosomes, Human, Y/genetics*; Azoospermia/genetics*
  20. Taiyeb Ali TB, Shapeen IM, Ahmed HB, Javed F
    J Investig Clin Dent, 2015 May;6(2):125-32.
    PMID: 24573974 DOI: 10.1111/jicd.12085
    The aim of the present study was to assess the efficacy of acellular dermal matrix (ADM) and subepithelial connective tissue grafts (sCTG) in the treatment of Miller class I and II gingival recession (GR) defects.
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