Browse publications by year: 2023

  1. Younis H, Loh CC, Singh C, Pichuthirumalai S, Kaur G, Bajwa AS, et al.
    SN Compr Clin Med, 2023;5(1):160.
    PMID: 37303486 DOI: 10.1007/s42399-023-01499-9
    The objective is to study factors that increase the likelihood of acute myocardial infarction (AMI) in hospitalized adult non-elderly patients with pneumonia compared to other medical inpatients and to understand the utilization rate of percutaneous coronary intervention (PCI) for AMI in inpatients with pneumonia and its related impact on hospitalization stay and cost. A population-based study was conducted using the Nationwide Inpatient Sample (NIS, 2019) with adult non-elderly inpatients (age 18-65 years) with a medical condition as their primary diagnosis and a co-diagnosis of pneumonia during hospitalization stay. This study sample was divided by the primary diagnosis of AMI versus other medical conditions (non-AMI). A logistic regression model was used to evaluate the odds ratio (OR) of predictors associated with AMI in patients with pneumonia. The results showed a direct relationship between increasing age and the likelihood of AMI in pneumonia inpatients with three times higher odds seen in 51-65 years of age (OR 2.95, 95% CI 2.82-3.09). The comorbidities included complicated hypertension (OR 2.84, 95% CI 2.78-2.89), diabetes with complications (OR 1.27, 95% CI 1.24-1.29), and drug abuse (OR 1.27, 95% CI 1.22-1.31) that increased the likelihood of AMI-related hospitalization. The utilization rate of surgical treatment (PCI) was 14.37% for the management of AMI in inpatients with pneumonia. Inpatients co-diagnosed with pneumonia and comorbidities such as hypertension and diabetes were more likely to be hospitalized for AMI. These at-risk patients should be considered for early risk stratification. Utilization of PCI was associated with a lower in-hospital mortality rate.
  2. Aili Hamzah AF, Hamzah MH, Che Man H, Jamali NS, Siajam SI, Ismail MH
    Heliyon, 2023 Jun;9(6):e16791.
    PMID: 37303543 DOI: 10.1016/j.heliyon.2023.e16791
    Organic loading influences the effectiveness of producing biogas through anaerobic digestion. This study set out to investigate the effect of organic loading on the anaerobic mesophilic digestion of cow dung, the parameters involved in the digestion process and to evaluate the kinetics. Anaerobic digestion of cow dung at different organic loading (gVS/L) of 14 gVS/L, 18gVS/L, 22 gVS/L, 26 gVS/L and 30 gVS/L were investigated. Increasing the organic loading increased the methane yield of the cow dung. The highest cumulative methane yield was observed at 30 gVS/L with 63.42 mL CH4/gVS while the highest biogas yield was reported at 192.53 mL/gVS with the highest methane content of 89%. In addition, the modified Gompertz model equation with an R2 of 0.9980 demonstrated strong consistency and a good fit between predicted and experimental data. The high number of substrates added to the systems when increasing the organic loading increased the λ and slow down the nutrient transport and hydrolysis. This study provides current information on the effects of organic loading on the anaerobic digestion of cow dung in batch mode, including experimental conditions and operational parameters.
  3. Ab Manaf N, Sa'at NH, A Rahim NAA, Kamaruddin SNAA, Abdullah SS, Omar K
    Heliyon, 2023 Jun;9(6):e16399.
    PMID: 37303545 DOI: 10.1016/j.heliyon.2023.e16399
    The Kenyir Lake side community offers numerous advantages to the local community. However, the problems of backwardness and poverty have been identified as the government's main challenges in its efforts to develop the community and maximise the advantages. Therefore, this study was conducted to identify the Kenyir Lake community's profile and assess its well-being. The study was conducted in three sub-districts near Tasik Kenyir, namely Kuala Berang, Hulu Telemong, and Jenagor, with a total of 510 respondents, who are heads of households (HOH). This study was carried out using a quantitative approach using questionnaire with a simple random sampling method. The findings of this study offered demographic profiling and discovered nine indicators of well-being, namely 1) Life Achievement, 2) Health Level, 3) Family Relationship, 4) Community Relationship, 5) Spiritual Level, 6) Safety Level and Social Problems, 7) Income or Finance, 8) Basic Facilities, and 9) Communication Technology. The study found that most respondents are satisfied with their lives now compared to 10 years ago. This study will help many parties to develop the Kenyir Lake Side Community, starting from the local authorities to the highest administration in the country.
  4. Mazlan N, Shukhairi SS, Muhammad Husin MJ, Shalom J, Saud SN, Abdullah Sani MS, et al.
    Heliyon, 2023 Jun;9(6):e16822.
    PMID: 37303562 DOI: 10.1016/j.heliyon.2023.e16822
    Plastic pollution is an emerging environmental concern in recent years due to continuous mass production and its slow degradation. Microplastics measuring between 5 mm and 1 μm are being ingested by marine animals and eventually by human consumption in form of seafood. The aim of this research was to evaluate microplastics isolated from sea cucumber Acaudina molpadioides in Pulau Langkawi. A total of 20 animals were collected and their gastrointestinal tract were digested using NaOH. Microplastics were isolated, filtered and identified through microscopic examination based on the colour, shape and size. The chemical composition of microplastics were further analyzed by FTIR to identify the functional group of polymers. A total of 1652 microplastics were found in A. molpadioides. Fibres (99.4%) and black color (54.4%) were the majority of microplastics observed in terms of shapes and colors. The size range within 0.5-1 μm and 1-2 μm were the highest abundance observed. There were two identified polymer types of microplastics obtained through FTIR which were polyethylene (PE) and polymethyl methacrylate (PMMA). In conclusion, microplastics were isolated from the gastrointestinal tract of A. molpadioides indicating that the animals were contaminated. Further research can be done on the toxicity effects of these microplastics towards human upon consumption of these animals as seafood.
  5. Bezak E, Borrás C, Hasford F, Karmaker N, Keyser A, Stoeva M, et al.
    Health Technol (Berl), 2023;13(3):495-503.
    PMID: 37303976 DOI: 10.1007/s12553-023-00756-0
    PURPOSE: Science diplomacy in medical physics is a relatively young research field and translational practice that focuses on establishing international collaborations to address some of the questions biomedical professionals face globally. This paper aims to present an overview of science diplomacy in medical physics, from an international perspective, illustrating the ways collaborations within and across continents can lead to scientific and professional achievements that advance scientific growth and improve patients care.

    METHODS: Science diplomacy actions were sought that promote collaborations in medical physics across the continents, related to professional and scientific aspects alike.

    RESULTS: Several science diplomacy actions have been identified to promote education and training, to facilitate research and development, to effectively communicate science to the public, to enable equitable access of patients to healthcare and to focus on gender equity within the profession as well as healthcare provision. Scientific and professional organizations in the field of medical physics across all continents have adopted a number of efforts in their aims, many of them with great success, to promote science diplomacy and to foster international collaborations.

    CONCLUSIONS: Professionals in medical physics can advance through international cooperation, by building strong communication across scientific communities, addressing rising demands, exchange scientific information and knowledge.

  6. Barteit S, Sié A, Zabré P, Traoré I, Ouédraogo WA, Boudo V, et al.
    Front Public Health, 2023;11:1153559.
    PMID: 37304117 DOI: 10.3389/fpubh.2023.1153559
    BACKGROUND: Climate change significantly impacts health in low-and middle-income countries (LMICs), exacerbating vulnerabilities. Comprehensive data for evidence-based research and decision-making is crucial but scarce. Health and Demographic Surveillance Sites (HDSSs) in Africa and Asia provide a robust infrastructure with longitudinal population cohort data, yet they lack climate-health specific data. Acquiring this information is essential for understanding the burden of climate-sensitive diseases on populations and guiding targeted policies and interventions in LMICs to enhance mitigation and adaptation capacities.

    OBJECTIVE: The objective of this research is to develop and implement the Change and Health Evaluation and Response System (CHEERS) as a methodological framework, designed to facilitate the generation and ongoing monitoring of climate change and health-related data within existing Health and Demographic Surveillance Sites (HDSSs) and comparable research infrastructures.

    METHODS: CHEERS uses a multi-tiered approach to assess health and environmental exposures at the individual, household, and community levels, utilizing digital tools such as wearable devices, indoor temperature and humidity measurements, remotely sensed satellite data, and 3D-printed weather stations. The CHEERS framework utilizes a graph database to efficiently manage and analyze diverse data types, leveraging graph algorithms to understand the complex interplay between health and environmental exposures.

    RESULTS: The Nouna CHEERS site, established in 2022, has yielded significant preliminary findings. By using remotely-sensed data, the site has been able to predict crop yield at a household level in Nouna and explore the relationships between yield, socioeconomic factors, and health outcomes. The feasibility and acceptability of wearable technology have been confirmed in rural Burkina Faso for obtaining individual-level data, despite the presence of technical challenges. The use of wearables to study the impact of extreme weather on health has shown significant effects of heat exposure on sleep and daily activity, highlighting the urgent need for interventions to mitigate adverse health consequences.

    CONCLUSION: Implementing the CHEERS in research infrastructures can advance climate change and health research, as large and longitudinal datasets have been scarce for LMICs. This data can inform health priorities, guide resource allocation to address climate change and health exposures, and protect vulnerable communities in LMICs from these exposures.

    MeSH terms: Activities of Daily Living; Africa; Algorithms; Humans; Research Design*; Climate Change*
  7. Sureshkumar S, Mustapha F, Yusoff H, Mwangi KJ, Marcus K, Kohlbrenner B, et al.
    Int J Public Health, 2023;68:1605861.
    PMID: 37304500 DOI: 10.3389/ijph.2023.1605861
    Objectives: This study assesses the opinions of health professionals in Malaysia on the disruption of non-communicable disease (NCD) services during the COVID-19 pandemic from March 2020 to January 2022. Methods: We conducted a cross-sectional online survey with 191 non-clinical public health workers and clinical health service workers in Malaysia from November 2021 to January 2022. Participants were recruited by the Malaysian Ministry of Health using major networks including key experts and practitioners. Secondary respondents were subsequently enrolled through snowballing. Results: The most notable issues raised by the survey participants relate to NCD service disruption, the redirection of NCD care resources, and NCD care being overburdened post-pandemic. Respondents also reported accounts of resilience and prompt reaction from the healthcare system, as well as calls for innovation. Conclusion: Most respondents perceived that the challenges arising from COVID-19 were mostly managed well by the healthcare system, which was able to provide the necessary services to NCD patients during this health emergency. However, the study identifies gaps in the health system response and preparedness capacity, and highlights solutions for strengthening NCD services.
    MeSH terms: Cross-Sectional Studies; Health Manpower; Humans; Malaysia/epidemiology; Pandemics
  8. Salem SM, Aldousari SA
    Urol Ann, 2023;15(2):197-201.
    PMID: 37304503 DOI: 10.4103/ua.ua_82_22
    INTRODUCTION: Gaining access to the kidney is crucial step in percutaneous nephrolithotomy (PCNL); it has a steep learning curve.

    OBJECTIVE: Describe the mathematical method to predict renal puncture angle and distance based on preoperative computed tomography (CT) measurements. Then evaluating how it correlates with measured values.

    PATIENTS AND METHODS: The study was prospectively designed. After ethical committee approval, the study uses data from preoperative CT to construct a triangle so we can estimate puncture depth and angle. A triangle of three points, the first is point of entry to the pelvicalyceal system (PCS), the second is point on the skin perpendicular to it, and the third where the needle punctures the skin. The needle travel is estimated using the Pythagorean theorem and puncture angle using the inverse sine function. We evaluated 40 punctures in 36 PCNL procedures. After PCS puncture using fluoroscopy-guided triangulation, we measured the needle travel distance and angle to the horizontal plane. Then compared the results with mathematically estimated values.

    RESULTS: We targeted posterior lower calyx in 21 (70%) case. The correlation between measured and estimated needle travel distance with Rho coefficient of 0.76 with P < 0.001. The mean difference between the estimated and the measured needle travel was - 0.37 ± 1.2 cm (-2.6-1.6). Measured and estimated angle correlate with Rho coefficient of 0.77 and P < 0.001. The mean difference between the estimated and the measured angle was 2° ± 8° (-21°-16°).

    CONCLUSION: Mathematical estimation of needle depth and angle for gaining access to the kidney correlates well with measured values.

  9. Tharmabalan RT
    Curr Dev Nutr, 2023 Apr;7(4):100054.
    PMID: 37304850 DOI: 10.1016/j.cdnut.2023.100054
    BACKGROUND: An essential dietary strategy to address the rapidly increasing risk of the double burden of malnutrition among indigenous populations around the world is to improve nutritional and food diversity utilizing varieties of traditional plant-based foods.

    OBJECTIVES: The objective of this research was to identify wild edible plants (WEPs) frequently consumed by the Semai and analyze their proximate and mineral composition to improve the adequacy of the local population's nutritional intake.

    METHODS: This study was conducted among 24 informants from 3 Semai settlements utilizing semistructured, ethnobotanical appraisal methods, proximate, and mineral analysis.

    RESULTS: This research first documents the common names, ethnobotanical names, and uses of 4 WEPs commonly consumed by the Semai: Sayur manis/pucuk manis [Sauropus androgynus (L.) Merr.], Pucuk ubi (Manihot esculenta Crantz), Saya/aying (Strobilanthes crispa Blume), and snegoh [Diplazium esculentum (Retz.) Sw.]. The nutritional content ranged from 3.2 to 7.7 g/100 g (ash), 2.9 to 7.2 g/100 g (protein), 1.5 to 6.2 g/100 g (carbohydrate). The mineral analysis showed that these plants contain considerable calcium, iron, potassium, and magnesium content, ranging from 176 to 243 mg/100 g, 0.7 to 2.8 mg/100 g, 295 to 527 mg/100 g, 32 to 97 mg/100 g. A comparative analysis was done with commercial market produce: Ipomoea aquatica, Brassica rapa subsp. Chinensis and Brassica oleracea var. alboglabra. The nutrient content for the 3 produce ranged from 1.2 to 2.6 g/100 g (protein), 2.18 to 4.67 g/100 g (carbohydrate), and 0.59 to 1.67 mg/100 g (iron). The results showed that Manihot esculenta had the highest carbohydrate, calcium, potassium, and magnesium content, whereas the highest ash and protein content was found in Diplazium esculentum.

    CONCLUSIONS: These findings show that these WEPs had higher nutritional and mineral concentrations than select market produce and can be used to strengthen food and nutrition security among the Semai. However, additional information regarding antinutrient, toxic compounds, methods of preparation, and consumption is required to determine how much they contribute to nutritional outcomes before these vegetables may be adopted as new crops. Curr Dev Nutr 2023;x:xx.

  10. Nasir NJN, Arifin N, Noordin KBAA, Yusop N
    J Taibah Univ Med Sci, 2023 Dec;18(6):1350-1363.
    PMID: 37305024 DOI: 10.1016/j.jtumed.2023.05.015
    Advances in cell-based regenerative therapy create new opportunities for the treatment of bone-related disorders and injuries, by improving the reparative phase of bone healing. Apart from the classical approach of bone grafting, the application of cell-based therapies, particularly stem cells (SCs), has gained a lot of attention in recent years. SCs play an important role in regenerative therapy due to their excellent ability to differentiate into bone-forming cells. Regeneration of new bone is regulated by a wide variety of signalling molecules and intracellular networks, which are responsible for coordinating cellular processes. The activated signalling cascade is significantly involved in cell survival, proliferation, apoptosis, and interaction with the microenvironment and other types of cells within the healing site. Despite the increasing evidence from studies conducted on signalling pathways associated with bone formation, the exact mechanism involved in controlling the differentiation stage of transplanted cells is not well understood. Identifying the key activated pathways involved in bone regeneration may allow for precise manipulation of the relevant signalling molecules within the progenitor cell population to accelerate the healing process. The in-depth knowledge of molecular mechanisms would be advantageous in improving the efficiency of personalised medicine and targeted therapy in regenerative medicine. In this review, we briefly introduce the theory of bone repair mechanism and bone tissue engineering followed by an overview of relevant signalling pathways that have been identified to play an important role in cell-based bone regenerative therapy.
  11. Paneerselvam GS, Goh KW, Kassab YW, Farrukh MJ, Goh BH, Lua PL, et al.
    Front Med (Lausanne), 2023;10:992870.
    PMID: 37305144 DOI: 10.3389/fmed.2023.992870
    BACKGROUND: End-stage renal disease is the last stage of chronic kidney disease and can affect the quality of life (QOL) of dialysis patients. The aim of this study was to assess the quality of life and examine its determinants.

    METHODS: A cross-sectional survey involving patients on dialysis in a tertiary hospital was conducted from July 2020 to September 2020. Demographic data were collected using a predesigned questionnaire. QOL was measured using the 36-item KDQOL questionnaire, and statistical analysis was carried out using SPSS version 25.

    RESULTS: Of the 108 patients, 59 were men and 49 were women, and the mean age was 48.15 ± 15.4 years. The results showed that there was no significant difference in the mean score of all components of health-related quality of life in different types of dialysis. The demographic data, which included age, gender, ethnicity, marital status, education level, occupation, and monthly income, did not significantly affect the QOL of dialysis patients. Patients with a dialysis duration of more than 5 years had a better QOL compared to other groups. Laboratory parameters such as low albumin and low hemoglobin showed a significant correlation with the health-related quality of life of dialysis patients.

    CONCLUSION: The quality of life among patients on dialysis was impaired, especially in terms of burden of the kidney disease. Hypoalbuminemia and anemia were the two factors that influenced QOL.

  12. Kathlyn TK, Zabiri H, Aldrich C, Liu X, Mohd Amiruddin AAA
    ACS Omega, 2023 Jun 06;8(22):19273-19286.
    PMID: 37305238 DOI: 10.1021/acsomega.2c08109
    An acid gas removal unit (AGRU) in a natural gas processing plant is designed specifically to remove acidic components, such as carbon dioxide (CO2) and hydrogen sulfide (H2S), from the natural gas. The occurrence of faults, such as foaming, and to a lesser extent, damaged trays and fouling, in AGRUs is a commonly encountered problem; however, they are the least studied in the open literature. Hence, in this paper, shallow and deep sparse autoencoders with SoftMax layers are investigated to facilitate early detection of these three faults before any significant financial loss. The dynamic behavior of process variables in AGRUs in the presence of fault conditions was simulated using Aspen HYSYS Dynamics. The simulated data were used to compare five closely related fault diagnostic models, i.e., a model based on principal component analysis, a shallow sparse autoencoder without fine-tuning, a shallow sparse autoencoder with fine-tuning, a deep sparse autoencoder without fine-tuning, and a deep sparse autoencoder with fine-tuning. All models could distinguish reasonably well between the different fault conditions. The deep sparse autoencoder with fine-tuning was best able to do so with very high accuracy. Visualization of the autoencoder features yielded further insight into the performance of the models, as well as the dynamic behavior of the AGRU. Foaming was relatively difficult to distinguish from normal operating conditions. The features obtained from the fine-tuned deep autoencoder in particular can be used to construct bivariate scatter plots as a basis for automatic monitoring of the process.
  13. Burki FA, Shah KU, Razaque G, Shah SU, Nawaz A, Saeed MD, et al.
    ACS Omega, 2023 Jun 06;8(22):19302-19310.
    PMID: 37305303 DOI: 10.1021/acsomega.2c08135
    Transdermal delivery is a potential alternative route to oral administration for drugs associated with stomach discomfort, such as flurbiprofen, a widely nonsteroidal anti-inflammatory drug (NSAID). This study aimed to design solid lipid nanoparticle (SLN) transdermal formulations of flurbiprofen. Chitosan-coated SLNs were prepared by the solvent emulsification method, and their properties and permeation profiles across the excised rat skin were characterized. The particle size of uncoated SLNs was at 695 ± 4.65 nm, which increased to 714 ± 6.13, 847 ± 5.38, and 900 ± 8.65 nm upon coating with 0.05, 0.10, and 0.20% of chitosan, respectively. The drug association efficiency was improved when a higher concentration of chitosan was employed over SLN droplets that endowed a higher affinity of flurbiprofen with chitosan. The drug release was significantly retarded as compared to the uncoated entities and followed non-Fickian anomalous diffusion that was depicted by "n" values of >0.5 and <1. Also, the total permeation of chitosan-coated SLNs (F7-F9) was significantly higher than that of the noncoated formulation (F5). Overall, this study has successfully designed a suitable carrier system of chitosan-coated SLNs that provide insight into the current conventional therapeutic approaches and suggest new directions for the advancements in transdermal drug delivery systems for improved permeation of flurbiprofen.
  14. Obaid MK, Almutairi MM, Alouffi A, Safi SZ, Tanaka T, Ali A
    Front Cell Infect Microbiol, 2023;13:1176013.
    PMID: 37305408 DOI: 10.3389/fcimb.2023.1176013
    Control of ticks and tick-borne pathogens is a priority for human and animal health. Livestock-holders extensively rely on acaricide applications for tick control. Different groups of acaricides including cypermethrin and amitraz have been consistently used in Pakistan. There has been a gap in understanding the susceptibility or resistance of Rhipicephalus microplus, the most prevalent tick in Pakistan, to acaricides. The present study aimed to molecularly characterize cypermethrin and amitraz targeted genes such as voltage-gated sodium channel (VGSC) and octopamine tyramine (OCT/Tyr) of R. microplus ticks in Khyber Pakhtunkhwa (KP), Pakistan to monitor the acaricides resistance. Tick specimens were collected from cattle and buffaloes in northern (Chitral, Shangla, Swat, Dir, and Buner), central (Peshawar, Mardan, Charsadda, Swabi, and Nowshera), and southern districts (Kohat, Karak, Lakki Marwat, Tank, and Dera Ismail Khan) of KP, Pakistan. Different concentrations of commercially available cypermethrin (10%) and amitraz (12.5%) were prepared for in vitro larval immersion tests (LIT). In LIT, the average mortality rate of immersed larvae was recorded that was increased gradually with an increase in the concentration of specific acaricide. The larvae's highest mortality rates (94.5% and 79.5%) were observed at 100-ppm of cypermethrin and amitraz, respectively. A subset of 82 R. microplus ticks was subjected to extract genomic DNA, followed by PCR to amplify partial fragments of VGSC (domain-II) and OCT/Tyr genes. The BLAST results of the consensus sequence of VGSC gene (domain-II) showed 100% identity with the acaricides susceptible tick sequence from the United States (reference sequence). Obtained identical sequences of OCT/Tyr genes showed maximum identity (94-100%) with the identical sequences reported from Australia (reference sequence), India, Brazil, Philippines, USA, South Africa, and China. Thirteen single nucleotide polymorphisms (10 synonymous and three non-synonymous) were observed at various positions of partial OCT/Tyr gene fragments. The SNP at position A-22-C (T-8-P) in OCT/Tyr gene has been linked to amitraz resistance in R. microplus ticks. Molecular analysis and LIT bioassay's findings indicate the availability of resistant R. microplus ticks in the KP region. To our understanding, this is the first preliminary study to monitor cypermethrin and amitraz resistance via molecular profiling of cypermethrin and amitraz targeted genes (VGSC and OCT/Tyr) in combination with in vitro bioassays (LIT) in R. microplus ticks from Pakistan.
    MeSH terms: Animals; Cattle; Humans; Larva/genetics; Octopamine; Tyramine
  15. Liu H, Liu N, Chong ST, Yau EKB, Ahmad Badayai AR
    Heliyon, 2023 May;9(5):e16023.
    PMID: 37305493 DOI: 10.1016/j.heliyon.2023.e16023
    [This corrects the article DOI: 10.1016/j.heliyon.2023.e14057.].
  16. Pham NT, Bunruangses M, Youplao P, Garhwal A, Ray K, Roy A, et al.
    Heliyon, 2023 May;9(5):e15749.
    PMID: 37305516 DOI: 10.1016/j.heliyon.2023.e15749
    The plasmonic antenna probe is constructed using a silver rod embedded in a modified Mach-Zehnder interferometer (MZI) ad-drop filter. Rabi antennas are formed when space-time control reaches two levels of system oscillation and can be used as human brain sensor probes. Photonic neural networks are designed using brain-Rabi antenna communication, and transmissions are connected via neurons. Communication signals are carried by electron spin (up and down) and adjustable Rabi frequency. Hidden variables and deep brain signals can be obtained by external detection. A Rabi antenna has been developed by simulation using computer simulation technology (CST) software. Additionally, a communication device has been developed that uses the Optiwave program with Finite-Difference Time-Domain (OptiFDTD). The output signal is plotted using the MATLAB program with the parameters of the OptiFDTD simulation results. The proposed antenna oscillates in the frequency range of 192 THz to 202 THz with a maximum gain of 22.4 dBi. The sensitivity of the sensor is calculated along with the result of electron spin and applied to form a human brain connection. Moreover, intelligent machine learning algorithms are proposed to identify high-quality transmissions and predict the behavior of transmissions in the near future. During the process, a root mean square error (RMSE) of 2.3332(±0.2338) was obtained. Finally, it can be said that our proposed model can efficiently predict human mind, thoughts, behavior as well as action/reaction, which can be greatly helpful in the diagnosis of various neuro-degenerative/psychological diseases (such as Alzheimer's, dementia, etc.) and for security purposes.
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