Browse publications by year: 2023

  1. Ahmad Z, Chan WM, Oon EYN
    Front Psychol, 2023;14:1043270.
    PMID: 36844264 DOI: 10.3389/fpsyg.2023.1043270
    PURPOSE: In this paper, we investigate two research queries pertaining to the success of small family business succession. First, we examine how the Big-5 personality traits of descendant entrepreneurs influence the success of their family business succession. Second, we investigate whether descendant entrepreneurs whose personality traits are congruent with the values of their family business, would lead to the success of their family business succession, through the mediating role of descendant entrepreneur-family business value congruence (DE-FBVC).

    METHODOLOGY: We rely on the person-organization fit theory for our conceptual framework and we collected primary data from 124 respondents designated as chairman and managing directors in small family businesses.

    RESULTS: Our results show that a descendant entrepreneur's openness, extroversion, conscientiousness, and agreeableness traits are likely to lead to successful family business succession, but a descendant entrepreneur with neuroticism trait is unlikely to do so. In addition, our results reveal that the DE-FBVC mediates the relationship between openness and extroversion traits with succession success positively, but between neuroticism trait and succession success negatively. By contrast, we find that DE-FBVC does not mediate the relationship between conscientiousness and agreeableness traits with succession success.

    ORIGINALITY: The findings of our study suggest that while four of the Big-5 personality traits matter for the success of small family business succession, specific personality traits of descendant entrepreneurs which are found to be congruent with the values of their family business, will also lead to succession success.

  2. Clarke NA, Akeroyd MA, Henshaw H, Hall DA, Mohamad WNW, Hoare DJ
    Front Psychol, 2023;14:1006349.
    PMID: 36844272 DOI: 10.3389/fpsyg.2023.1006349
    This study presents the executive disruption model (EDM) of tinnitus distress and subsequently validates it statistically using two independent datasets (the Construction Dataset: n = 96 and the Validation Dataset: n = 200). The conceptual EDM was first operationalised as a structural causal model (construction phase). Then multiple regression was used to examine the effect of executive functioning on tinnitus-related distress (validation phase), adjusting for the additional contributions of hearing threshold and psychological distress. For both datasets, executive functioning negatively predicted tinnitus distress score by a similar amount (the Construction Dataset: β = -3.50, p = 0.13 and the Validation Dataset: β = -3.71, p = 0.02). Theoretical implications and applications of the EDM are subsequently discussed; these include the predictive nature of executive functioning in the development of distressing tinnitus, and the clinical utility of the EDM.
  3. Masan SEPP, Rusydi F, Prabowo WAE, Elisandro D, Mark-Lee WF, Karim NA, et al.
    ACS Omega, 2023 Feb 21;8(7):6523-6529.
    PMID: 36844535 DOI: 10.1021/acsomega.2c06888
    Adsorbates coverage plays a crucial role in a catalysis reaction. In hydrodeoxygenation (HDO), which involves high hydrogen pressure, hydrogen coverage on the surface may affect the adsorption of other adsorbates. The HDO is used in green diesel technology to produce clean and renewable energy from organic compounds. This motivates us to study the hydrogen coverage effect on methyl formate adsorption on MoS2 as a model case of the actual HDO. We calculate the methyl formate adsorption energy as a function of hydrogen coverage using density functional theory (DFT) and then comprehensively analyze the physical origin of the results. We find that methyl formate can have several adsorption modes on the surface. The increased hydrogen coverage can stabilize or destabilize these adsorption modes. However, finally, it leads to convergence at high hydrogen coverage. We extrapolated the trend further and concluded that some adsorption modes might not exist at high hydrogen coverage, while others remain.
  4. Sayani JKS, English NJ, Khan MS, Lal B, Kamireddi VR
    ACS Omega, 2023 Feb 21;8(7):6218-6224.
    PMID: 36844557 DOI: 10.1021/acsomega.2c02823
    This work presents the effect of hydrogen sulfide gas on the phase behavior of both methane gas hydrate formation and CO2 gas hydrate formation. For this, the thermodynamic equilibrium conditions for various gas mixtures containing CH4/H2S and CO2/H2S are initially found by simulation using PVTSim software. These simulated results are compared using an experimental approach and the available literature. Then, the thermodynamic equilibrium conditions generated by simulation are used for generating Hydrate Liquid-Vapor-Equilibrium (HLVE) curves to understand the phase behavior of gases. Further, the effect of hydrogen sulfide on the thermodynamic stability of methane and carbon dioxide hydrates was studied. It was clearly observed from the results that an increase in H2S composition in the gas mixture decreases the stability of CH4 and CO2 hydrates.
  5. Mohd Zaini NS, Lim EJ, Ahmad NH, Gengatharan A, Wan-Mohtar WAAQI, Abd Rahim MH
    Food Bioproc Tech, 2023 Feb 20.
    PMID: 36844636 DOI: 10.1007/s11947-023-03020-5
    The processing of edible insects as an alternative source of nutrition may be a key driver in the development of a sustainable food and feed system. This review will study two industrial types of insects-mealworms and locusts-and summarize evidence related to the impact of processing on their micro- and macronutritional characteristics. The focus will be on their potential use as food for human consumption as opposed to animal feed. Literature has indicated that these two insects have the potential to provide protein and fat qualities comparable to or better than traditional mammalian sources. For example, mealworms-the larval form of the yellow mealworm beetlepossess a higher fat content, while adult locusts are rich in fibers, especially chitin. However, due to the different matrix and nutrient compositions, the processing of mealworms or locusts at a commercial scale needs to be tailored to minimize nutritional loss and maximize cost efficiency. The stages of preprocessing, cooking, drying, and extraction are the most critical control points for nutritional preservation. Thermal cooking applications such as microwave technology have demonstrated promising results, but the generation of heat may contribute to a certain nutritional loss. In an industrial context, drying using freeze dry is the preferred choice due to its uniformity, but it can be costly while increasing lipid peroxidation. During the extraction of nutrients, the use of green emerging technologies such as high hydrostatic pressure, pulsed electric field, and ultrasound may provide an alternative method to enhance nutrient preservation.
  6. Tian K, Hao L, Xuan W, Phongsatha T, Hao R, Wei W
    Front Public Health, 2023;11:1034231.
    PMID: 36844825 DOI: 10.3389/fpubh.2023.1034231
    INTRODUCTION: Disseminating health science information via the internet has become an essential means for improving Chinese residents' health literacy, which has received constant attention from the Chinese government. Therefore, it is important to explore Chinese residents' perceived value and emotional response to mobile health science information for determining Chinese residents' satisfaction and use intention.

    METHODS: This study applied the cognition-affect-conation model to evaluate the perceived value, arousal, pleasure, trust, satisfaction, and continuous use intention. A mobile device was used to obtain health science information from 236 Chinese residents via an online survey and the data were analyzed using partial least squares (PLS)-structural equation modeling.

    RESULTS: The results showed that Chinese residents' perceived value of health science information obtained using the mobile device directly affect the degree of arousal (β = 0.412, P < 0.001), pleasure (β = 0.215, P < 0.01), and trust (β = 0.339, P < 0.001). The degree of arousal (β = 0.121, P < 0.01), pleasure (β = 0.188, P < 0.01), and trust (β = 0.619, P < 0.001) directly affected Chinese residents' satisfaction, which further affected their continuous use intention (β = 0.513, P < 0.001). Similarly, trust directly affected Chinese residents' continuous use intention (β = 0.323, P < 0.001). The degree of arousal directly affected their degree of pleasure (β = 0.304, P < 0.001), and pleasure also imposed a direct effect on trust (β = 0.293, P < 0.001).

    DISCUSSION: The result of this study provided an academic and practical reference to improve mobile health science popularization information. Affective changes have imposed an important effect on Chinese residents' continuous use intention. High-quality, diversified and frequent use of health science information can significantly increase residents' continuous use intention, improving their health literacy as a consequence.

    MeSH terms: Cognition; Emotions; Surveys and Questionnaires; Intention*; Pleasure*
  7. Mokhzan NS, Sutan R, Yasin RM, Yamat H
    Front Public Health, 2023;11:1042124.
    PMID: 36844841 DOI: 10.3389/fpubh.2023.1042124
    BACKGROUND: Caregivers of elderly people need the right education and empowering skills to manage their own health needs and the elderly people they care for.

    OBJECTIVE: The study aimed to explore youth perceptions of the My-Elderly-Care-Skills Module intervention and its perceived feasibility.

    METHODS: This study involved youth respondents (18-30 years old) from low-income households who are accountable to providing care for independent older people (60 years or above) living in the same house. A qualitative study using a case study design was used to assess youth perceptions based on the content of the My-Elderly-Care-Skills module, by focusing on its implementation usage and usefulness for the care of the elderly. A total of 30 youths voluntarily participated in the online training workshop during the COVID-19 pandemic movement restriction order period. There were multiple sources of data, such as video recorded on reflection of care given at home, text messages in a WhatsApp group, and in-depth interviews during small group online meetings. Data were recorded and transcribed verbatim for common themes before a theme analysis was conducted. Inductive content analysis was performed after the saturation point was met.

    RESULTS: Thematic analysis derived two domains of feasibility: operational and technical feasibility. There were three themes under operational practicality (improving awareness, addressing the caregiving skills needs, and seeking resources for knowledge) and three themes for technical practicality (easily used and informative, skill in effective communication, and program fulfillment).

    CONCLUSION: It was verified that it is feasible for young caregivers of the elderly to participate in the My-Elderly-Care-Skills training intervention as it helps in improving knowledge and skills performance in managing and caring for the elderly.

    MeSH terms: Adolescent; Adult; Aged; Humans; Caregivers; Qualitative Research; Young Adult; Pandemics*
  8. Airak S, Sukor NSA, Rahman NA
    Transp Res Interdiscip Perspect, 2023 Mar;18:100784.
    PMID: 36844954 DOI: 10.1016/j.trip.2023.100784
    The COVID-19 pandemic has disrupted travel behaviours due to the need for movement restrictions. The restrictions adversely affected various aspects of health and the economy. This study aimed to investigate factors affecting trip frequency during the recovery period of the COVID-19 pandemic in Malaysia. An online national cross-sectional survey was conducted to collect data in conjunction with different movement restriction policies. The questionnaire includes socio-demographics, experience with COVID-19, risk perception of COVID-19, and trip frequency on several activities during the pandemic. Mann Whitney U was conducted to determine whether there were statistically significant differences between the socio-demographic factors for the respondents in the first and second surveys. Results show no significant difference in socio-demographic factors except for the level of education. The results indicate that the respondents from both surveys were comparable. Next, Spearman correlation analyses were conducted to find significant correlations between trip frequencies toward socio-demographics, experience with COVID-19 and risk perception. There was a correlation between the frequency of travel and risk perception for both surveys. Regression analyses were performed based on the findings to investigate trip frequency determinants during the pandemic. Perceived risk, gender, and occupation influenced the trip frequencies for both surveys. By understanding the influence of risk perception on the frequency of travel, the government can identify the appropriate policy during a pandemic or health emergency to avoid impeding normal travel behaviour. Thus, people's mental and psychological well-being are not negatively affected.
  9. Chong NT, Chin VY, Haneline MT, Wong YK
    J Chiropr Med, 2023 Mar;22(1):20-26.
    PMID: 36844990 DOI: 10.1016/j.jcm.2022.05.001
    OBJECTIVE: The purpose of this study was to identify and compare the ergonomic risk factors of year 4 and year 5 dental students attending International Medical University.

    METHODS: This was an exploratory, observational study evaluating ergonomic risk factors among year 4 and year 5 dental students, with a total of 89 participants. The students' ergonomic risk components were evaluated using the Rapid Upper Limb Assessment (RULA) worksheet. Descriptive statistics were used to analyze the RULA scores, and the Mann-Whitney U test served to determine the difference of ergonomic risk between year 4 and year 5 dental students.

    RESULTS: The descriptive analysis showed that the participants' (N = 89) median final RULA score was 6.00 (standard deviation = 0.716). One-year difference in the years of clinical practice did not produce a significant difference in the final RULA score (U = 913.0, P = 0.49). The final RULA scores showed year 4 dental students had a higher mean ranking (year 4 = 46.65, year 5 = 43.23). Furthermore, the Mann-Whitney U test indicated that this was not statistically significant (U = 913.0, P = 0.49).

    CONCLUSION: The descriptive analysis showed that the final RULA score of the participants indicated that the participants were in a high-risk category for experiencing work-related musculoskeletal disorders due to poor ergonomics. Contributing physical factors included working in asymmetric, awkward, and static positions in a confined workspace, infrequent use of dental loupes, and utilization of dental chairs that were not ergonomically appropriate.

  10. Miga M, Jahari PNS, Parimannan S, Rajandas H, Latiff MAB, Jing Wei Y, et al.
    Mitochondrial DNA B Resour, 2023;8(2):292-296.
    PMID: 36845007 DOI: 10.1080/23802359.2023.2179355
    In the present study, the nearly complete mitochondrial genome of Euphaea ochracea was described and its phylogenetic position in the family Euphaeidae was analyzed. Here, we recovered 13 protein-coding genes, 22 transfer RNAs, 2 ribosomal RNAs and a partial control region, resulting in a mitogenome length of 15,545bp. All protein-coding genes were initiated by the typical ATN codon except nad3 and nad1, which utilizes the TTG codon. Four protein-coding genes (cox1, cox2, cox3 and nad5) are terminated by an incomplete stop codon T, while others end with either a TAA or TAG codon. The intergenic spacer region, S5, is absent in this mitogenome, supporting the lack of this region as a specific character in damselflies. Phylogenetic analysis showed that the newly sequenced E. ochracea is phylogenetically closer to E. ornata with a high support value.
  11. Omar B, Apuke OD, Nor ZM
    Curr Psychol, 2023 Feb 21.
    PMID: 36845207 DOI: 10.1007/s12144-023-04343-4
    Research on fake news is growing, yet the relative influence of different factors on fake news sharing and how it can be reduced are still understudied. To fill this gap, this study treats user motivation and online environment as intrinsic and extrinsic factors and examines the role of fake news awareness as a prevention against the spread of fake news. This study describes the results of a Malaysian sample (N = 451) to determine the effects of intrinsic factor (altruism, information sharing, socialization and status seeking) and extrinsic factor (trust in network, homophily, norm of reciprocity and tie strength) on fake news sharing using Partial Least Square (PLS). Unlike past research, we treated the two main factors as higher order-constructs. Our findings revealed a stronger appeal of online environment than user motivation in determining fake news sharing among social media users in Malaysia. We also found that high fake news awareness determined low fake news sharing. This result suggests the importance of fake news awareness as an intervention strategy to curtail the spread of fake news. Future research is needed to build upon our findings to be tested at cross-cultural settings and also employ time series analysis to better understand the effect of increasing awareness of fake news over time.
  12. Dhamanti I, Suwantika AA, Adlia A, Yamani LN, Yakub F
    Int J Gen Med, 2023;16:609-618.
    PMID: 36845341 DOI: 10.2147/IJGM.S400458
    The COVID-19 pandemic had a severe global impact. A range of campaigns and activities, including vaccines, are being implemented to counteract this pandemic. Using observational data, the goal of this scoping review is to identify adverse events connected with COVID-19 vaccinations. We conduct a scoping study and searched three databases from the start of the COVID-19 pandemic in 2020 through June 2022. Based on our criteria and searched keywords, the review included eleven papers in total, with the majority of the studies being conducted in developed countries. The study populations varied and included general community populations, healthcare professionals, military forces, and patients with systemic lupus and cancer. This study includes vaccines from Pfizer-BioNTech, Oxford-AstraZeneca, Sinopharm, and Moderna. The COVID-19 vaccine-related adverse events were classified into three types: local side effects, systemic side effects, and other side effects such as allergies. The adverse reactions to COVID-19 vaccines are mild to moderate in severity, with no significant influence or interference in individual daily activities and no unique patterns in cause of death among vaccine-related deaths. According to the findings of these investigations, the COVID-19 vaccine is safe to administer and induces protection. It is vital to convey accurate information to the public about vaccination side effects, potential adverse responses, and the safety level of the vaccines supplied. Multiple strategies must be implemented at the individual, organizational, and population levels to eliminate vaccine hesitance. Future studies could investigate the vaccine's effect on people of various ages and medical conditions.
  13. Nik Mohd Rosdy NMM, Mohd Amin NAS, Roslan N
    Int J Dent, 2023;2023:9924186.
    PMID: 36845626 DOI: 10.1155/2023/9924186
    OBJECTIVES: This study aims to identify the pH level and subsequently the erosive potential of beverages including their sugar content.

    MATERIALS AND METHODS: Beverages were purchased from a local convenience store, and some of the beverages were freshly prepared. The acidity of each beverage was identified using a calibrated pH meter. The pH was obtained in triplicate, and the results were expressed in average values with standard deviations. The pH values were then used to determine their erosive potential and the sugar content was obtained from the packaging and recorded.

    RESULTS: A total of 167 beverages were purchased and categorized. The beverages were categorized into 15 groups: milk tea, hawker drinks, instant drinks, fresh fruit juices, milk, energy drinks, designer coffee, soda, canned drinks, cultured milk, vegetable juices, cordials, bottled fruit drinks, tea, and mineral water. The pH value ranges from 2.65 to 7.85. Seven beverages (4.2%) were classified as extremely erosive, 53 beverages (31.1%) were classified as erosive, and 36 beverages (21.6%) were classified as minimally erosive. In total, 57.5% of the beverages were potentially erosive, and most of the soda and energy drinks were erosive. The highest sugar content per 100 g was BOH Teh Tarik Original (71.8 g), whereas the highest sugar content per serving was Carabao energy drink (10.8 g).

    CONCLUSION: High sugar content and low acidic content of beverages could have a negative impact on the dentition. An intervention is required from a public health perspective to regulate the consumption of sweetened and flavored beverages.

  14. Maqbool M, Tirmazi SSM, Shakoor A, Akram Z, Nazir R, Chohan AN, et al.
    Biomed Res Int, 2023;2023:1044541.
    PMID: 36845639 DOI: 10.1155/2023/1044541
    BACKGROUND: Despite of having improved endodontic file designs as well as the reinforced metal alloy file structure, intracanal endodontic file separation (EFS) is still a very problematic and worrisome dental incident, which usually occurs without any visible signs of permanent deformation. Further, there have been conflicting reports regarding the clinical significance of leaving separated files within root canals.

    AIMS: The aim of this study was to look into the current perceptions and awareness about file separation during endodontic treatment among the dental house officers (DHOs).

    MATERIALS AND METHODS: A novel validated questionnaire comprising of 15 close-ended questions was distributed anonymously via Google Forms through email to 1100 DHOs across Pakistan. The questionnaire consisted of two parts: the first component (Section I) collected demographic data and the second component (Section II) investigated the causes of EFS during root canal treatment. Following the completion of socioeconomic information, including age and gender, the DHOs were asked to answer a few questions about the various reasons for endodontic instrument fracture.

    RESULTS: A total of 800 responses were recorded, with an effective rate of 72.8%. The majority of the DHOs (p value < 0.001) perceived that endodontic instrument fracture occurred in the posterior (61.5%) and apical third of the canal (50.5%) and in older permanent dentition (67.3%), possibly due to patient anxiety (62%). Better choice of instrument (61.15%), operators' experience (95.3%), knowledge (87.5%), and proper root canal cleaning (91.1%) are believed to be the vital steps in reducing endodontic file separation/fracture. Furthermore, majority of them (p value < 0.001) perceived that stainless steel was a superior alloy for filing instruments. Manual files tend to be more prone to fractures due to repeated use than rotary files.

    CONCLUSION: This study demonstrated that young DHOs had adequate knowledge and awareness regarding the potential predisposing factors and handling techniques for EFS. This study thereby provides an evaluating tool to access the insights of the current perceptions and awareness of DHOs concerning EFS.

    MeSH terms: Aged; Dental Alloys; Dental Instruments; Dental Pulp Cavity; Equipment Design; Equipment Failure; Humans; Perception; Root Canal Therapy*; Titanium/chemistry
  15. Gosztonyi M, Havran D, Pollák Z, Berlinger E
    Data Brief, 2023 Apr;47:108946.
    PMID: 36845647 DOI: 10.1016/j.dib.2023.108946
    The dataset presented in this paper consists of a network of interpersonal lending relations from a single village of a deprivated area of Hungary. The data are originated from quantitative surveys from May 2014 to June 2014. The data collection was embedded in a Participatory Action Research (PAR) which aimed to investigate the financial survival strategies of low-income households in a Hungarian village in a disadvantaged region. The directed graphs of lending and borrowing are a unique dataset that empirically captures a hidden and informal financial activity between households. The network contains 164 households and 281 credit connections among them.
  16. Dasor MM, Jafridin AA, Azhar AA, Asma AAA, Manivannan PC, Bilal S, et al.
    Int J Public Health, 2023;68:1604383.
    PMID: 36846156 DOI: 10.3389/ijph.2023.1604383
    Objectives: This study aimed to measure depression, anxiety and stress (DAS) among undergraduate dental students during the COVID-19 pandemic, identify key contributing factors of stress and explore the association of emotional intelligence to DAS. Methods: A multi-centre, cross-sectional study was conducted across four universities in Malaysia. The study administered a questionnaire consisting of the validated Depression Anxiety Stress Scale (DASS), Dental Environment Stress (DES), Emotional Intelligence Scale (EI) and 10 statements assessing COVID-19 specific potential stressor factors. Results: Participants included 791 students across four universities. Abnormal levels of DAS were identified in 60.6%, 66.8% and 42.6% of the study participants, respectively. "Pressure of performance," "Faculty administration" and "Self-efficacy belief" were the highest rated stressors. On-time graduation was the main COVID-19 specific stressor factor. EI was negatively correlated with DAS scores (p < 0.001). Conclusion: The levels of DAS during COVID-19 pandemic in this population is high. However, participants with higher EI presented with lower DAS suggesting that EI may be a form of coping resource and should be enhanced in this population.
    MeSH terms: Anxiety/epidemiology; Cross-Sectional Studies; Depression/epidemiology; Humans; Stress, Psychological/epidemiology; Stress, Psychological/psychology; Emotional Intelligence; Pandemics
  17. Al-Najjar BO, Abbas MA, Sibai OA, Saqallah FG, Al-Kabariti AY
    RSC Med Chem, 2023 Feb 22;14(2):239-246.
    PMID: 36846363 DOI: 10.1039/d2md00285j
    P2Y12 has a key role in platelet aggregation and thrombus formation via an ADP-induced platelet activation mechanism. Recently, P2Y12 antagonists have become of great interest in the clinical management of antithrombotic therapy. In light of this, we explored the pharmacophoric space of P2Y12 using structure-based pharmacophore modelling. Subsequently, genetic algorithm and multiple linear regression analyses were conducted to select the best combination of physicochemical descriptors and pharmacophoric models to create useful predictive quantitative structure-activity relationship (QSAR) equation (r 2 = 0.9135, r (adj) 2 = 0.9147, r (PRESS) 2 = 0.9129, LOF = 0.3553). One pharmacophoric model emerged in the QSAR equation and was validated by analysing receiver operating characteristic (ROC) curves. The model was then used to screen 200 000 compounds from the National Cancer Institute (NCI) database. The top-ranked hits were in vitro tested, where their IC50's range between 4.20 to 35.00 μM when measured via the electrode aggregometry assay. Whilst, the VASP phosphorylation assay showed 29.70% platelet reactivity index for NSC618159, which is superior to that of ticagrelor.
  18. Vit P, van der Meulen J, Diaz M, Pedro SRM, Esperança I, Zakaria R, et al.
    Curr Res Food Sci, 2023;6:100386.
    PMID: 36846470 DOI: 10.1016/j.crfs.2022.11.005
    The biodiversity of Ecuadorian stingless bees is almost 200 species. Traditional pot-honey harvest in Ecuador is mostly done from nests of the three genera selected here Geotrigona Moure, 1943, Melipona Illiger, 1806, and Scaptotrigona Moure, 1942. The 20 pot-honey samples collected from cerumen pots and three ethnic honeys "abeja de tierra", "bermejo", and "cushillomishki" were analyzed for qualitative and quantitative targeted 1H-NMR honey profiling, and for the Honey Authenticity Test by Interphase Emulsion (HATIE). Extensive data of targeted organic compounds (41 parameters) were identified, quantified, and described. The three honey types were compared by ANOVA. Amino acids, ethanol, hydroxymethylfurfural, aliphatic organic acids, sugars, and markers of botanical origin. The number of phases observed with the HATIE were one in Scaptotrigona and three in Geotrigona and Melipona honeys. Acetic acid (19.60 ± 1.45 g/kg) and lactic acid (24.30 ± 1.65 g/kg) were particularly high in Geotrigona honey (in contrast to 1.3 g/kg acetic acid and 1.6 g/kg lactic acid in Melipona and Scaptotrigona), and with the lowest fructose + glucose (18.39 ± 1.68) g/100g honey compared to Melipona (52.87 ± 1.75) and Scaptotrigona (52.17 ± 0.60). Three local honeys were tested using PCA (Principal Component Analysis), two were assigned with a correct declared bee origin, but "bermejo" was not a Melipona and grouped with the Scaptotrigona cluster. However after HCA (Hierarchical Cluster Analysis) the three honeys were positioned in the Melipona-Scaptotrigona cluster. This research supports targeted 1H-NMR-based profiling of pot-honey metabolomics approach for multi-parameter visualization of organic compounds, as well as descriptive and pertained multivariate statistics (HCA and PCA) to discriminate the stingless bee genus in a set of Geotrigona, Melipona and Scaptotrigona honey types. The NMR characterization of Ecuadorian honey produced by stingless bees emphasizes the need for regulatory norms. A final note on stingless bee markers in pot-honey metabolites which should be screened for those that may extract phylogenetic signals from nutritional traits of honey. Scaptotrigona vitorum honey revealed biosurfactant activity in the HATIE, originating a fingerprint Honey Biosurfactant Test (HBT) for the genus in this set of pot-honeys.
  19. Ahmed W, Ali S, Waqas H, Asghar M, Erum N
    Glob Soc Welf, 2023 Feb 22.
    PMID: 36846516 DOI: 10.1007/s40609-023-00268-9
    The governments have been facing the challenges to develop tailored strategies to decrease COVID vaccine hesitancy (CVH) and refusal and increase the acceptability and uptake to ensure the protection of public health. In Pakistan, it has been a great challenge for the government to increase the acceptability of the COVID vaccine. CVH has been a great hurdle to achieving this objective. The authors found it imperative to identify and evaluate the factors of CVH in Pakistan. For this purpose, the authors used an integrated multicriteria decision analysis method (MCDM) by combining Delphi and DEMATEL methods. The factors of CVH have been identified and finalized using the Delphi method. The experts' opinions were obtained to evaluate the factors. The DEMATEL method was used to find out the most critical factor(s) of CVH. Moreover, the cause/effect relationship was also developed to have a better understating of factors and their relationships. The analysis revealed "ineffective public awareness strategies" as the most critical factor of CVH followed by "misinformation and disinformation, conspiracy theories", and "acquired knowledge". The study also examined the cause-and-effect relationship between the prioritized factors. The government in Pakistan introduced successful efforts to deal with the COVID-19 pandemic, yet the government could do more to increase vaccine acceptance. For this purpose to serve effective scientific and evidence-based public awareness strategies are needed to increase the acquired knowledge and deal with misinformation, disinformation, and conspiracy theories to increase vaccine acceptance. The government could sue the media, especially social media to increase vaccination. The findings of the study provide a detailed understanding of the CVH in Pakistan and develop a comprehensive public health strategy to deal with any health-related potential issues in the future.
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