Affiliations 

  • 1 PAP Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Seri Begawan BE1410, Brunei
  • 2 Faculty of Pharmacy, Universiti Teknologi MARA, Shah Alam 42300, Malaysia
  • 3 Faculty of Engineering, Universiti Teknologi Malaysia, Johor Bahru 81310, Malaysia
  • 4 Department of Pharmacy, State University of Bangladesh, Dhaka 1205, Bangladesh
  • 5 College of Medical Sciences, Azal University for Human Development, Amran P.O. Box 447, Yemen
  • 6 Biofunctional Molecule Exploratory (BMEX) Research Group, School of Pharmacy, Monash University Malaysia, Subang Jaya 47500, Malaysia
  • 7 Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Kuala Lumpur 43400, Malaysia
Molecules, 2021 Dec 30;27(1).
PMID: 35011441 DOI: 10.3390/molecules27010209

Abstract

Coriandrum sativum (C. sativum), belonging to the Apiaceae (Umbelliferae) family, is widely recognized for its uses in culinary and traditional medicine. C. sativum contains various phytochemicals such as polyphenols, vitamins, and many phytosterols, which account for its properties including anticancer, anti-inflammatory, antidiabetic, and analgesic effects. The cardiovascular benefits of C. sativum have not been summarized before, hence this review aims to further evaluate and discuss its effectiveness in cardiovascular diseases, according to the recent literature. An electronic search for literature was carried out using the following databases: PubMed, Scopus, Google Scholar, preprint platforms, and the Cochrane Database of Systematic Reviews. Articles were gathered from the inception of the database until August 2021. Moreover, the traditional uses and phytochemistry of coriander were surveyed in the original resources and summarized. As a result, most of the studies that cover cardiovascular benefits and fulfilled the eligibility criteria were in vivo, while only a few were in vitro and clinical studies. In conclusion, C. sativum can be deemed a functional food due to its wide range of cardiovascular benefits such as antihypertensive, anti-atherogenic, antiarrhythmic, hypolipidemic as well as cardioprotective effects.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.