Prevalence of surgical wound infection and related factors in patients after long bone surgery: A systematic review and meta-analysis

Asadi K 1 , Tehrany PM 2 , Salari A 1 , Ghorbani Vajargah P 3 , Mollaei A 3 , Sarafi M 4 Show all authors , Ashoobi MT 5 , Esmaeili Delshad MS 6 , Takasi P 3 , Fouladpour A 1 , Karkhah S 3 , Farzan R 7 , Aris A 1

Affiliations 

  • 1 Department of Orthopedics, Orthopedic Research Center, Poorsina Hospital, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran
  • 2 Department of Orthopaedic Surgery, Faculty of Medicine, National University of Malaysia, Bani, Malaysia
  • 3 Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran
  • 4 Department of Vascular Surgery, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
  • 5 Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
  • 6 Department of General Surgery, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
  • 7 Department of Plastic & Reconstructive Surgery, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Int Wound J, 2023 Jul 10.
PMID: 37424390 DOI: 10.1111/iwj.14300

Abstract

The goal of this systematic review and meta-analysis is to provide an overview of the prevalence of surgical wound infection and related factors in patients after long bone surgery. A comprehensive, systematic search was conducted in different international electronic databases, such as Scopus, PubMed, Web of Science and Persian electronic databases such as Iranmedex and Scientific Information Database using keywords extracted from Medical Subject Headings such as "Prevalence", "Surgical wound infection", "Surgical site infection" and "Orthopedics" from the earliest to the May 1, 2023. The appraisal tool for cross-sectional studies (AXIS tool) evaluates the quality of the included studies. A total of 71 854 patients undergoing long bone surgery participated in 12 studies. The pooled prevalence of surgical wound infection in patients who underwent long bone surgery reported in the 12 studies was 3.3% (95% CI: 1.5%-7.2%; I2  = 99.39%; p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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