A case of rotenone poisoning from ingesting Derris trifoliata Lour. (Tuba fruit/pod) in Malaysia

Yeoh SL 1 , Choong PS 2 , Zakaria R 3 , Kamaruzaman NA 4 , Md Rashid S 5 , Razali MF 6 Show all authors , Ismail AK 7

Affiliations 

  • 1 Department of Paediatric, Hospital Sultanah Bahiyah, Alor Setar, Kedah, Malaysia. Electronic address: silingmy@gmail.com
  • 2 Department of Paediatric, Hospital Sultanah Bahiyah, Alor Setar, Kedah, Malaysia. Electronic address: pheiksian@yahoo.com
  • 3 School of Biological Sciences, Universiti Sains Malaysia, Minden, Penang, Malaysia. Electronic address: rahmadz@usm.my
  • 4 National Poison Centre, Universiti Sains Malaysia, Minden, Penang, Malaysia. Electronic address: azzalia@usm.my
  • 5 National Poison Centre, Universiti Sains Malaysia, Minden, Penang, Malaysia. Electronic address: sazaroni@usm.my
  • 6 National Poison Centre, Universiti Sains Malaysia, Minden, Penang, Malaysia. Electronic address: fadhli_razali@usm.my
  • 7 Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; Hospital Canselor Tuanku Mukhriz, Jalan Yaakob Latif, Bandar Tun Razak, Kuala Lumpur, Malaysia. Electronic address: khaldun_ismail@yahoo.com
Toxicon, 2024 Jan;237:107557.
PMID: 38072318 DOI: 10.1016/j.toxicon.2023.107557

Abstract

Derris trifoliata is mainly found in mangrove area in tropical regions and the plant extract is traditionally used for fishing by poisoning. This is the first case report of rotenone poisoning in a child from ingesting Derris trifoliata seed. The child developed altered consciousness, vomiting, hypotension, metabolic acidosis, and acute kidney injury. Species identification of this case requires the collaborative efforts of various agencies. She survived from the poisoning with no neurological sequelae.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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