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Inhibitory effects of palm tocotrienol-rich fraction supplementation on bilirubin-metabolizing enzymes in hyperbilirubinemic adult rats

Kamisah Y 1 , Lim JJ 2 , Lim CL 2 , Asmadi AY 3

Affiliations 

  • 1 Department of Pharmacology, Faculty of Medicine, UKM Medical Center, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
  • 2 Department of Biomedical Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
  • 3 Faculty of Traditional and Complementary Medicine, Cyberjaya University College of Medical Sciences, Cyberjaya, Selangor, Malaysia
PLoS One, 2014;9(2):e89248.
PMID: 24586630 DOI: 10.1371/journal.pone.0089248

Abstract

Phenylhydrazine, a hemolytic agent, is widely used as a model of experimental hyperbilirubinemia. Palm tocotrienol-rich fraction (TRF) was shown to exert beneficial effects in hyperbilirubinemic rat neonates.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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