Impact of vessel volume on thermodilution measurements in patients with coronary microvascular dysfunction

Sakai K 1 , Storozhenko T 1 , Mizukami T 1 , Ohashi H 2 , Bouisset F 1 , Tajima A 1 Show all authors , van Hoe L 3 , Gallinoro E 4 , Botti G 5 , Mahendiran T 1 , Pardaens S 1 , Brouwers S 1 , Fawaz S 6 , Keeble TR 6 , Davies JR 6 , Sonck J 1 , De Bruyne B 1 , Collet C 1

Affiliations 

  • 1 Cardiovascular Center Aalst, OLV Clinic, Aalst, Belgium
  • 2 Department of Cardiology, Aichi Medical University, Aichi, Japan
  • 3 Department of Radiology, OLV Clinic, Aalst, Belgium
  • 4 Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy
  • 5 Interventional Cardiology Unit, IRCCS Ospedale San Raffaele, Milan, Italy
  • 6 Essex Cardiothoracic Centre, Mid and South Essex NHS Foundation Trust, Basildon, UK
Catheter Cardiovasc Interv, 2024 May;103(6):885-896.
PMID: 38566527 DOI: 10.1002/ccd.31020

Abstract

BACKGROUND: Two invasive methods are available to estimate microvascular resistance: bolus and continuous thermodilution. Comparative studies have revealed a lack of concordance between measurements of microvascular resistance obtained through these techniques.

AIMS: This study aimed to examine the influence of vessel volume on bolus thermodilution measurements.

METHODS: We prospectively included patients with angina with non-obstructive coronary arteries (ANOCA) undergoing bolus and continuous thermodilution assessments. All patients underwent coronary CT angiography to extract vessel volume. Coronary microvascular dysfunction was defined as coronary flow reserve (CFR) 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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