Serotonin transporter gene polymorphism and its association with bipolar disorder across different ethnic groups in Malaysia

Mohamed Saini S 1 , Nik Jaafar NR , Sidi H , Midin M , Mohd Radzi A , Abdul Rahman AH

Affiliations 

  • 1 Department of Psychiatry, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Jalan Yaacob Latif, 56000, Cheras, Kuala Lumpur, Malaysia. Electronic address: suriati@medic.ukm.my
Compr Psychiatry, 2014 Jan;55 Suppl 1:S76-81.
PMID: 23410635 DOI: 10.1016/j.comppsych.2012.12.005

Abstract

The risk variants have been shown to vary substantially across populations and a genetic study in a heterogeneous population might shed a new light in the disease mechanism. This preliminary study aims to determine the frequency of the serotonin transporter gene polymorphism (5-HTTLPR) in the three main ethnic groups in Malaysia and its association with bipolar disorder.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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