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Characterization of the functional domain of β2-microglobulin from the Asian seabass, Lates calcarifer

Mohd-Padil H 1 , Tajul-Arifin K , Mohd-Adnan A

Affiliations 

  • 1 School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia
PLoS One, 2010;5(10):e13159.
PMID: 20949082 DOI: 10.1371/journal.pone.0013159

Abstract

β2-Microglobulin (β(2)M) is the light chain of major histocompatibility class I (MHC I) that binds non-covalently with the α heavy chain. Both proteins attach to the antigen peptide, presenting a complex to the T cell to be destroyed via the immune mechanism.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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