Exogenous leptin administration decreases sperm count and increases the fraction of abnormal sperm in adult rats

Haron MN 1 , D'Souza UJ , Jaafar H , Zakaria R , Singh HJ

Affiliations 

  • 1 Department of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia
Fertil Steril, 2010 Jan;93(1):322-4.
PMID: 19709655 DOI: 10.1016/j.fertnstert.2009.07.995

Abstract

Daily intraperitoneal injection of 5-30 microg/kg body weight of leptin for 42 days to adult rats decreases sperm count and increases the fraction of abnormal sperm.

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