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Clinical predictors of a positive troponin T test in patients presenting with probable acute coronary syndromes

Omar AR 1 , Ping C 2 , Tan HC 3 , Lim YT 4

Affiliations 

  • 1 Omar A R, MRCP. Cardiac Department, National University Hospital, The Heart Institute, 5 Lower Kent Ridge, Road Level 3, Main Building, Singapore 119074
  • 2 Ping Chai, MRCP. Cardiac Department, National University Hospital, The Heart Institute, 5 Lower Kent Ridge, Road Level 3, Main Building, Singapore 119074
  • 3 Tan H C, FRCP. Cardiac Department, National University Hospital, The Heart Institute, 5 Lower Kent Ridge, Road Level 3, Main Building, Singapore 119074
  • 4 Lim Y T, FRCP. Cardiac Department, National University Hospital, The Heart Institute, 5 Lower Kent Ridge, Road Level 3, Main Building, Singapore 119074
Med J Malaysia, 2005 Mar;60(1):50-3.
PMID: 16250280

Abstract

Acute coronary syndrome (ACS) patients with positive troponin T (TnT) test are at higher risk for death and myocardial reinfarction. They would significantly benefit from early aggressive pharmacologic and invasive therapy. However, TnT test is not widely available. This retrospective study of 173 patients with ACS showed: that prolonged or repetitive episodes of angina at rest in the previous 24 hours (p = 0.01) and evidence of myocardial ischaemia on ECG (p < 0.001) were associated with positive TnT tests (> or = 0.1 ng/mL). The two variables in combination showed 100% positive predictive value, facilitating early identification and streamlining of therapy.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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