Conodiparines A-D, new bisindoles from Tabernaemontana. Reversal of vincristine-resistance with cultured cells

Kam TS 1 , Sim KM , Koyano T , Toyoshima M , Hayashi M , Komiyama K

Affiliations 

  • 1 Department of Chemistry, University of Malaya, Kuala Lumpur, Malaysia
Bioorg Med Chem Lett, 1998 Jul 07;8(13):1693-6.
PMID: 9873417

Abstract

Four new bisindoles of the vobasine-iboga type, conodiparines A-D were obtained from Tabernaemontana corymbosa which showed appreciable activity in reversing resistance in vincristine-resistant KB cells.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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