Mechanisms underlying the antihypertensive effect of Alstonia scholaris

Bello I 1 , Usman NS 1 , Mahmud R 2 , Asmawi MZ 3

Affiliations 

  • 1 Department of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia (USM), 11800 Pulau Pinang, Malaysia
  • 2 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, University Sains Malaysia (USM), 11800 Pulau Pinang, Malaysia
  • 3 Department of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia (USM), 11800 Pulau Pinang, Malaysia. Electronic address: amzaini@usm.my
J Ethnopharmacol, 2015 Dec 4;175:422-31.
PMID: 26429073 DOI: 10.1016/j.jep.2015.09.031

Abstract

Alstonia scholaris has a long history of use in the Ayurveda traditional treatment of various ailments including hypertension. We have reported the blood pressure lowering activity of the extract of A. scholaris. The following research aim to delineate the pharmacological mechanism involve in the antihypertensive action.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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