Injection speed of spinal anaesthesia for Caesarean delivery in Asian women and the incidence of hypotension: A randomised controlled trial

Chiang CF; Hasan MS; Tham SW; Sundaraj S; Faris A; Ganason N

doi:10.1016/j.jclinane.2017.03.025

Injection speed of spinal anaesthesia for Caesarean delivery in Asian women and the incidence of hypotension: A randomised controlled trial

Chiang CF ¹ , Hasan MS ² , Tham SW ³ , Sundaraj S ³ , Faris A ³ , Ganason N ³

Affiliations

¹ Department of Anaesthesiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
² Department of Anaesthesiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address: shahnaz@ummc.edu.my
³ Department of Anaesthesia, Hospital Tengku Ampuan Rahimah, 41200 Klang, Selangor, Malaysia

J Clin Anesth, 2017 Jun;39:82-86.

PMID: 28494915 DOI: 10.1016/j.jclinane.2017.03.025

Abstract

STUDY OBJECTIVE: The purpose of this investigation was to determine if a slower speed of spinal anaesthesia injection would reduce the incidence of hypotension.

STUDY DESIGN: Randomised controlled trial.

SETTING: Tertiary level hospital in Malaysia.

PATIENTS: 77 patients undergoing elective Caesarean delivery.

INTERVENTION: Differing speeds of spinal injection.

MEASUREMENTS: Systolic blood pressure was assessed every minute for the first 10min and incidence of hypotension (reduction in blood pressure of >30% of baseline) was recorded. The use of vasopressor and occurrence of nausea/vomiting were also recorded.

MAIN RESULTS: 36 patients in SLOW group and 41 patients in FAST group were recruited into the study. There was no significant difference in blood pressure drop of >30% (p=0.497) between the two groups. There was no difference in the amount of vasopressor used and incidence of nausea/vomiting in both groups.

CONCLUSION: In our study population, there was no difference in incidence of hypotension and nausea/vomiting when spinal injection time is prolonged beyond 15s to 60s.

TRIAL REGISTRATION: ClinicalTrials.govNCT02275897. Registered on 15 October 2014.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.