Affiliations 

  • 1 Paediatric Department, Hospital Teluk Intan, Teluk Intan, Perak, Malaysia. kaeytan@yahoo.co.uk
  • 2 Paediatric Department, Hospital Slim River, Slim River, Perak, Malaysia
  • 3 Paediatric Department, Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia
  • 4 Public Health Department, Medicine Faculty, Universiti Kebangsaan, Kuala Lumpur, Malaysia
  • 5 Clinical Research Centre, Ipoh, Perak, Malaysia
BMC Pediatr, 2019 05 29;19(1):174.
PMID: 31142302 DOI: 10.1186/s12887-019-1550-3

Abstract

BACKGROUND: Prolonged neonatal jaundice (PNNJ) is often caused by breast milk jaundice, but it could also point to other serious conditions (biliary atresia, congenital hypothyroidism). When babies with PNNJ receive a routine set of laboratory investigations to detect serious but uncommon conditions, there is always a tendency to over-investigate a large number of well, breastfed babies. A local unpublished survey in Perak state of Malaysia revealed that the diagnostic criteria and initial management of PNNJ were not standardized. This study aims to evaluate and improve the current management of PNNJ in the administrative region of Perak.

METHODS: A 3-phase quasi-experimental community study was conducted from April 2012 to June 2013. Phase l was a cross-sectional study to review the current practice of PNNJ management. Phase ll was an interventional phase involving the implementation of a new protocol. Phase lll was a 6 months post-interventional audit. A registry of PNNJ was implemented to record the incidence rate. A self-reporting surveillance system was put in place to receive any reports of biliary atresia, urinary tract infection, or congenital hypothyroidism cases.

RESULTS: In Phase I, 12 hospitals responded, and 199 case notes were reviewed. In Phase II, a new protocol was developed and implemented in all government health facilities in Perak. In Phase III, the 6-month post-intervention audit showed that there were significant improvements when comparing mean scores of pre- and post-intervention: history taking scores (p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.