• 1 Instituto de Nanociencia de Aragón , Universidad de Zaragoza , 50018 Zaragoza , Spain
  • 2 Melville Laboratory for Polymer Synthesis, Department of Chemistry , University of Cambridge , Cambridge CB2 1EW , United Kingdom
  • 3 Cavendish Laboratory, Department of Physics , University of Cambridge , JJ Thomson Avenue , Cambridge CB3 0HE , United Kingdom
  • 4 Spanish National Cancer Research Centre (CNIO) , Melchor Fernández Almagro 3 , 28029 Madrid , Spain
  • 5 Laboratory of Biomolecular Research, Division of Biology and Chemistry , Paul Scherrer Institute , 5232 Villigen PSI , Switzerland
  • 6 Department of Physics , University of Patras , Patras 26500 , Greece
  • 7 Laboratoire Léon Brillouin, CNRS, CEA , Université Paris-Saclay , 91191 Gif-sur-Yvette cedex , France
J Am Chem Soc, 2019 09 11;141(36):14021-14025.
PMID: 31422657 DOI: 10.1021/jacs.9b07506


The binding of imidazolium salts to cucurbit[8]uril, CB[8], triggers a stepwise self-assembly process with semiflexible polymer chains and crystalline nanostructures as early- and late-stage species, respectively. In such a process, which involves the crystallization of the host-guest complexes, the guest plays a critical role in directing self-assembly toward desirable morphologies. These include platelet-like aggregates and two-dimensional (2D) fibers, which, moreover, exhibit viscoelastic and lyotropic properties. Our observations provide a deeper understanding of the self-assembly of CB[8] complexes, with fundamental implications in the design of functional 2D systems and crystalline materials.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.