Affiliations 

  • 1 Food and Biomaterial Engineering Research Group, School of Chemical & Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, UTM, 81310, Johor Bahru, Johor, Malaysia
  • 2 Institute of Bioproduct Development, School of Chemical & Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, UTM, 81310, Johor Bahru, Johor, Malaysia
Heliyon, 2019 Oct;5(10):e02571.
PMID: 31667409 DOI: 10.1016/j.heliyon.2019.e02571

Abstract

Total phenolic content (TPC) and antioxidant properties of xanthone extract from mangosteen pericarp via microwave-assisted extraction (MAE) method was optimized by response surface methodology (RSM). The MAE extraction conditions to obtain optimum antioxidant-rich xanthone extract were at 2.24 min of irradiation time, 25 mL/g of solvent-to-solid ratio and 71% of ethanol concentration. The predicted results for four responses were as follows; 320.31 mg gallic acid equivalent/g extract, 83.63% and 93.77% inhibition (DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2'-Azino-bis-3-ethylbenzthiazoline-6-sulfonic acid) assays), and 144.56 mg Trolox equivalent/g extract (FRAP, Ferric reducing antioxidant power). The predicted and actual values were statistically insignificant (P > 0.05). Therefore, these results confirmed that the examined model was acceptable and relevant. MAE led to a slightly similar antioxidant capacity and a higher extraction of α-mangostin, a major xanthone of mangosteen pericarp as compared to water bath-maceration technique.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.