Therapeutic potential of Artemisia vulgaris: An insight into underlying immunological mechanisms

Soon L 1 , Ng PQ 1 , Chellian J 2 , Madheswaran T 3 , Panneerselvam J 3 , Gupta G 4 Show all authors , Nammi S 5 , Hansbro NG 6 , Hsu A 7 , Dureja H 8 , Mehta M 9 , Satija S 9 , Hansbro PM 6 , Dua K 6 , Collet T 10 , Chellappan DK 2

Affiliations 

  • 1 School of Pharmacy, International Medical University (IMU), Bukit Jalil, Kuala Lumpur, 57000, Malaysia
  • 2 Department of Life Sciences, School of Pharmacy, International Medical University (IMU), Bukit Jalil, Kuala Lumpur, 57000, Malaysia
  • 3 Department of Pharmaceutical Technology, School of Pharmacy, International Medical University (IMU), Bukit Jalil, Kuala Lumpur, 57000, Malaysia
  • 4 Suresh Gyan Vihar University
  • 5 School of Science and Health, Western Sydney University, NSW, 2751, Australia; NICM Health Research Institute, Western Sydney University, NSW, 2751, Australia
  • 6 Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) and School of Biomedical Sciences and Pharmacy, The University of Newcastle (UoN), Callaghan, NSW 2308, Australia; Centre for Inflammation, Centenary Institute, Sydney, NSW 2050, Australia; Faculty of Science, University of Technology Sydney, Ultimo NSW 2007, Australia
  • 7 Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) and School of Biomedical Sciences and Pharmacy, The University of Newcastle (UoN), Callaghan, NSW 2308, Australia
  • 8 Department of Pharmaceutical Sciences, Maharishi Dayanand University, Rohtak, Haryana 124001, India
  • 9 School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi G.T. Road (NH-1), Phagwara-144411, Punjab, India
  • 10 Indigenous Medicines Group, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Kelvin Grove, Brisbane, Queensland 4059, Australia
J Environ Pathol Toxicol Oncol, 2019;38(3):205-216.
PMID: 31679308 DOI: 10.1615/JEnvironPatholToxicolOncol.2019029397

Abstract

Artemisia vulgaris is a traditional Chinese herb believed to have a wide range of healing properties; it is traditionally used to treat numerous health ailments. The plant is commonly called mugwort or riverside wormwood. The plant is edible, and in addition to its medicinal properties, it is also used as a culinary herb in Asian cooking in the form of a vegetable or in soup. The plant has garnered the attention of researchers in the past few decades, and several research studies have investigated its biological effects, including antioxidant, anti-inflammatory, anticancer, hypolipidemic, and antimicrobial properties. In this review, various studies on these biological effects are discussed along with the tests conducted, compounds involved, and proposed mechanisms of action. This review will be of interest to the researchers working in the field of herbal medicine, pharmacology, medical sciences, and immunology.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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