Affiliations 

  • 1 Integrative Medicine Cluster, Advanced Medical & Dental Institute, Universiti Sains Malaysia, Pulau Pinang 13200, Malaysia. Electronic address: boonyihhui@hotmail.com
  • 2 Integrative Medicine Cluster, Advanced Medical & Dental Institute, Universiti Sains Malaysia, Pulau Pinang 13200, Malaysia. Electronic address: nurnadhirah@usm.my
  • 3 Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia; Universiti Malaya Centre for Ionic Liquids (UMCiL), Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia. Electronic address: sharifahm@um.edu.my
  • 4 Chemical Approaches for Food Applications Research Group, Faculty of Science, Chulalongkorn University, Bangkok, Thailand; Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand. Electronic address: puttaruksa.w@chula.ac.th
  • 5 School of Chemical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia. Electronic address: ohasnah@usm.my
  • 6 Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia; Universiti Malaya Centre for Ionic Liquids (UMCiL), Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia. Electronic address: muggundha@um.edu.my
Food Chem, 2020 Jun 01;314:126214.
PMID: 31972404 DOI: 10.1016/j.foodchem.2020.126214

Abstract

Poly(β-cyclodextrin-ionic liquid) grafted magnetic nanoparticles combined with 1-octanol as supramolecular solvents (SUPRASs) presenting new ferrofluid was developed and successfully applied in the dispersive liquid-phase microextraction of seven representative polycyclic aromatic hydrocarbons. One variable at-a-time (OVAT) analysis and response surface methodology (RSM) were used for efficient optimization of the main variables. The calibration curves were found to be linear in the range of 0.1-150 ng mL-1 with correlation of determinations (R2) ranging from 0.9944 to 0.9986. Detection limits ranged at 0.02-0.07 ng mL-1 for all studied PAHs. The intra and inter-day precision values (RSD %) were in the range of 1.80%-7.56% and 2.97%-8.23%, respectively. The ferrofluid showed a satisfactory reproducibility between 1.72% and 5.90%, and acceptable recovery values at 84%-110% were obtained for the real samples analysis. The optimized method was successfully applied to access the content safety of the PAHs studied in a variety of commercial food and beverages available in Malaysia.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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