Affiliations 

  • 1 Hospital Sultanah Nora Ismail, Department of Internal Medicine, Johor, Malaysia. lowqinjian@moh.gov.my
  • 2 Hospital Sultanah Nora Ismail, Department of Internal Medicine, Johor, Malaysia
  • 3 Hospital Lahad Datu, Department of Internal Medicine, Sabah, Malaysia
  • 4 Hospital Melaka, Department of Emergency Medicine, 75400 Melaka, Malaysia
Med J Malaysia, 2020 07;75(4):442-444.
PMID: 32724013

Abstract

There are increasing reports of methanol poisoning (MP) incidence worldwide. In Malaysia, the largest first methanol poisoning was reported in Selangor in 2013 with a total of 41 patients and cluster of cases been reported from the country since then. Often MP involved adulterated alcohol containing more than the legal permissible concentration of methanol. Methanol is rapidly absorbed and metabolised into formic acid which causes variable symptoms of the central nervous system such as blindness, seizure, coma and gastrointestinal disturbances. Mortality could reach up to 83% as reported using the coma state, pH and pCO2 level in the worst-case scenario.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.