Antimycobacterial activity of selected medicinal plants traditionally used in Sudan to treat infectious diseases

Abuzeid N 1 , Kalsum S 2 , Koshy RJ 2 , Larsson M 3 , Glader M 2 , Andersson H 2 Show all authors , Raffetseder J 2 , Pienaar E 2 , Eklund D 2 , Alhassan MS 4 , AlGadir HA 4 , Koko WS 4 , Schön T 5 , Ahmed Mesaik M 6 , Abdalla OM 7 , Khalid A 4 , Lerm M 8

Affiliations 

  • 1 Medicinal and Aromatic Plants Research Institute, National Center for Research, P.O. Box: 2404, Khartoum 11111, Sudan; Department of Clinical Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, P.O.Box 382, Omdurman,Sudan; Division of Microbiology and Molecular Medicine, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, 58185 Linkoping, Sweden
  • 2 Division of Microbiology and Molecular Medicine, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, 58185 Linkoping, Sweden
  • 3 Department of Clinical Microbiology, Linköping University Hospital, 58185 Linkoping, Sweden
  • 4 Medicinal and Aromatic Plants Research Institute, National Center for Research, P.O. Box: 2404, Khartoum 11111, Sudan
  • 5 Department of Clinical Microbiology and Infectious diseases, Kalmar County Hospital, SE-391 85 Kalmar, Sweden
  • 6 Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
  • 7 Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
  • 8 Division of Microbiology and Molecular Medicine, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, 58185 Linkoping, Sweden. Electronic address: maria.lerm@liu.se
J Ethnopharmacol, 2014 Nov 18;157:134-9.
PMID: 25261689 DOI: 10.1016/j.jep.2014.09.020

Abstract

The emergence of multidrug-resistant strains of Mycobacterium tuberculosis underscores the need for continuous development of new and efficient methods to determine the susceptibility of isolates of Mycobacterium tuberculosis in the search for novel antimycobacterial agents. Natural products constitute an important source of new drugs, and design and implementation of antimycobacterial susceptibility testing methods are necessary to evaluate the different extracts and compounds. In this study we have explored the antimycobacterial properties of 50 ethanolic extracts from different parts of 46 selected medicinal plants traditionally used in Sudan to treat infectious diseases.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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