Affiliations 

  • 1 Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan
  • 2 School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • 3 Punjab Medical Center, Lahore, Pakistan
  • 4 Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia
  • 5 Institute of Public Health and Community Medicine Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan
  • 6 Department of Internal Medicine, University of Medicine and Pharmacy, Hue University, Hue City, Vietnam
  • 7 Department of Physiology, King George's Medical University, Lucknow, India
  • 8 Department of General Medicine, Tan Tock Seng Hospital, Singapore, Singapore
  • 9 Division of Nephrology Department of Medicine, Yong Loo Lin School of Medicine, Singapore, Singapore
  • 10 Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
J Clin Hypertens (Greenwich), 2021 03;23(3):496-503.
PMID: 33377597 DOI: 10.1111/jch.14163

Abstract

Although short and long sleep duration are both risk factors of cardiovascular disease (CVD), the recent meta-analyses have been shown that long sleep duration was closely associated with CVD mortality. While the specific mechanism underlying the association between long sleep duration and CVD remains unclear, long sleep duration was shown to be associated with arterial stiffness and blood pressure variability (BPV) in many Asian populations. This review article will focus on the pathophysiology of long sleep duration, arterial stiffness, BPV and their effects on CVD. To set the stage for this review, we first summarize the current insights for the relationship between long sleep duration and CVD in relation to arterial stiffness and BPV.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.