Affiliations 

  • 1 Division of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea
  • 2 Department of Cardiovascular Medicine, The Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, National Research Centre for Translational Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
  • 3 Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Selangor Darul Ehsan, Malaysia
  • 4 Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
  • 5 Department of Medicine, National Yang-Ming Chiao Tung University College of Medicine, Taipei, Taiwan
  • 6 Department of Internal Medicine, University of Medicine and Pharmacy, Hue University, ., Vietnam
  • 7 Department of Internal Medicine, General Medicine and Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan
  • 8 University of the East Ramon Magsaysay Memorial Medical Center Inc., Quezon City, Philippines
  • 9 Division of Cardiology, Cardiovascular Hospital, Yonsei Health System, Seoul, South Korea
  • 10 Punjab Medical Center, Lahore, Pakistan
  • 11 Section of Cardiology, Department of Medicine, Medical Center Manila, Manila, Philippines
  • 12 Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia-National Cardiovascular Center, Harapan Kita, Jakarta, Indonesia
  • 13 Fortis Hospitals, Chennai, Tamil Nadu, India
  • 14 Department of General Medicine, Tan Tock Seng Hospital, Singapore, Singapore
  • 15 Division of Nephrology Department of Medicine, Yong Loo Lin School of Medicine, Singapore, Singapore
  • 16 JC School of Public Health and Primary Care, JC Institute of Ageing, SH Big Data Decision Analytics Research Centre, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong
  • 17 Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • 18 Indian Society of Hypertension, King George's Medical University, Lucknow, Uttar Pradesh, India
  • 19 Department of Internal Medicine, National Taiwan University College of Medicine, Taipei City, Taiwan
  • 20 Divisions of Hypertension and Heart Failure, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
PMID: 37878534 DOI: 10.1111/jch.14729

Abstract

For adopting recently introduced hypertension phenotypes categorized using office and out of office blood pressure (BP) for the diagnosis of hypertension and antihypertension drug therapy, it is mandatory to define the corresponding out of office BP with the specific target BP recommended by the major guidelines. Such conditions include white-coat hypertension (WCH), masked hypertension (MH), white-coat uncontrolled hypertension (WUCH), and masked uncontrolled hypertension (MUCH). Here, the authors review the relevant literature and discuss the related issue to facilitate the use of corresponding BPs for proper diagnosis of WCH, MH, WUCH, and MUCH in the setting of standard target BP as well as intensive target BP. The methodology of deriving the corresponding BP has evolved from statistical methods such as standard deviation, percentile value, and regression to an outcome-based approach using pooled international cohort study data and comparative analysis in randomized clinical trials for target BPs such as the SPRINT and STEP studies. Corresponding BPs to 140/90 and 130/80 mm Hg in office BP is important for safe and strict achievement of intensive BP targets. The corresponding home, daytime, and 24-h BPs to 130/80 mm Hg in office BP are 130/80, 130/80, and 125/75 mm Hg, respectively. However, researchers have found some discrepancies among the home corresponding BPs. As tentative criterion for de-escalation of antihypertensive therapy as shown in European guidelines was 120 mm Hg in office BP, corresponding home, daytime, and 24-h systolic BPs to 120 mm Hg in office systolic BP are 120, 120, and 115 mm Hg, respectively.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.