Introduction: Recently mobile communication technology had tremendous advances and became the priority for most of the users with some opponent opinions that highlight the accountability and the privacy issues in using these messaging applications. WhatsApp is scored to be the first top used messaging application worldwide that is used in 180 countries by about 1.5 billion population. This research aims to determine the staff reflections regarding the WhatsApp usage for organizational communication. Methods: This study is implied among the staff at the medical and health life science cluster, Management and Science University (MSU), Malaysia. A questionnaire was distributed to all the staff through an online google form. Responses were analysed by the ‘Statistical Package for Social Sciences’ (SPSS) Version 24.0. Results: Results showed that all the staff responded (100%) are using WhatsApp for organizational communication with variable degrees of satisfaction; 8.1% are extremely satisfied, 61.3 % are satisfied, 12.9% are not satisfied and 16.1 % are extremely not satisfied. Their level of satisfaction is significantly affected by the respondent’s age, benefit of usage, and the time of messaging. Conclusion: To ensure effectiveness of communication through WhatsApp, it should be through official groups and the organization should put specific announced rules for the time of usage and the content of messages to be posted to all members.