Higher levels of lead and aluminium are associated with increased risk of falls among community-dwelling older adults: An 18-month follow-up study

Ooi TC 1 , Singh DKA 1 , Shahar S 1 , Rajab NF 1 , Sharif R 1

Affiliations 

  • 1 Centre for Healthy Ageing and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
Geriatr Gerontol Int, 2021 Nov;21(11):1026-1032.
PMID: 34590402 DOI: 10.1111/ggi.14284

Abstract

AIM: The present study aims to determine the association of trace elements and oxidative and DNA damage biomarkers with fall incidence among community-dwelling older adults.

METHODS: This study is part of the Long-term Research Grant Scheme - Towards Useful Ageing cohort study in Malaysia. Of a total of 174 participants with complete trace elements and oxidative and DNA damage data during baseline, only 147 (84.5%) were successfully followed up after 18 months. Participants who experienced any fall events in the previous 18 months during the follow-up were categorized as fallers.

RESULTS: Thirty participants (20.4%) reported at least one fall in the previous 18 months. The mean concentrations of aluminium, lead and zinc were significantly higher (P 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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