Affiliations 

  • 1 Universiti Teknologi MARA, Non-Destructive Biomedical and Pharmaceutical Research Centre , Puncak Alam, 42300, Selangor , Malaysia +60 3 32584691 ; wongtinwui@salam.uitm.edu.my
Expert Opin Drug Deliv, 2014 Sep;11(9):1419-34.
PMID: 24960192 DOI: 10.1517/17425247.2014.924499

Abstract

Vaginal infection is widespread and > 80% of females encounter such infections during their lives. Topical treatment and prevention of vaginal infection allows direct therapeutic action, reduced drug doses and adverse effects, convenient administration and improved compliance. The advent of nanotechnology results in the use of nanoparticulate vehicle to control drug release, to enhance dosage form mucoadhesive properties and vaginal retention, and to promote mucus and epithelium permeation for both extracellular and intracellular drug delivery.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.