Displaying publications 1 - 20 of 429 in total

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  1. Stock I
    Med Monatsschr Pharm, 2014 Jan;37(1):4-10; quiz 11-2.
    PMID: 24490433
    Hand, foot and mouth disease (HFMD) is a highly contagious, world-wide distributed viral illness that affects predominantly children. It is caused by several enteroviruses, such as coxsackieviruses A6, A10, A16 and enterovirus 71. In most cases, HFMD follows a benign and self-limiting course. After an incubation period of 3 to 10 days, fever and sore throat, the first symptoms of the disease, appear. A few days later, maculopapular or vesicular eruptions form on the palms and soles as well as in the oral cavity. Since the year 2000, several large HFMD outbreaks have been reported in many Asian regions such as China, Malaysia and Vietnam. In some of these outbreaks, high incidences of severe progressive HFMD forms with some fatalities were observed. Such diseases have been caused primarily by enterovirus 71 strains and were characterized frequently by sudden onset of fever, encephalitis/meningitis and severe respiratory symptoms such as pulmonary edema. Further severe neurological and cardiac complications have also been observed during these outbreaks. Recently, some HFMD outbreaks caused by the coxsackievirus A6 have been reported in several parts of the world. These illnesses also affected adults and were characterized by more severe symptoms of "classical" HFMD. In addition, outbreaks of coxsackievirus-A6-associated HFMD in many countries were associated with onychomadesis, with the loss of nails occurring up to two months after initial symptoms. Treatment of "classical" HFMD is usually symptomatic, a generally recommended antiviral therapy does not exist. In severe HFMD cases, suitable treatment also encompasses mechanical ventilation, as well as the additional application of antiviral agents such as ribavirin. In the last years, several novel agents with good in vitro and in vivo activity against enteroviruses have been developed. A vaccine against HFMD is not yet available.
    Matched MeSH terms: Hand, Foot and Mouth Disease/diagnosis; Hand, Foot and Mouth Disease/drug therapy*; Hand, Foot and Mouth Disease/epidemiology; Hand, Foot and Mouth Disease/virology
  2. Iqbal QM
    Med J Malaysia, 1977 Mar;31(3):252-5.
    PMID: 904523
    Matched MeSH terms: Hand Injuries/epidemiology
  3. Al-Husuny, A., Rampal, L., Manohar, A.
    MyJurnal
    Work-Related Hand Injuries (WRHIs) may result in disability and diminished productivity and cause economic impacts not only to the individual, worker’s families and industries, but to the local community as well.
    Objectives: To determine the prevalence of severe Work-Related Hand Injuries (WRHIs) and factors associated at a tertiary hospital.
    Methods: A pre-tested validated questionnaire was used to obtain data. All patients 18 years and above with WRHIs seen at a tertiary hospital between January 2010 and June 2010 were included in the study. Data was analysed using SPSS version 18.
    Results: Out of the 297 industrial accidents, 74 (24.9%) were WRHIs. Among those with WRHIs, (47.3%) of them had severe hand injuries. The overall mean age of the respondents was 30.36 (± 9.54 SD) years. Majority (82.5%) of the injuries occurred between Mondays to Friday. Majority (70.1%) of hand injuries were caused by machine and 48.6% of the hand injuries occurred when the hand was caught in the operating part of the machine. Majority (62.1%) of the respondents had fingers’ injuries and 32.4% had open fracture. Bivariate analysis showed that there was significant association between severity of WRHIs and locations of injury, mechanisms of injury, sources of injury and sectors of industry (p < 0.05). Logistic regression analysis showed that WRHIs was significantly associated with source of injury and sector of industry. Respondents with hand injury resulted while operating on mechanical machine was 26 times more likely to report severe WRHIs than those with other sources of their hand injury like (sharp tool, heavy door, and wet floor). Respondents working in metal-machinery industries were eight times more likely to report severe WRHIs than those who working in other sectors of industry like (wood-furniture, constriction, food preparing, service and automotive).
    Conclusions: WRHIs contributed to 24.9% of all industrial accidents seen at the emergency department and orthopaedic clinic and 47.3% of the respondents with WRHIs had severe hand injuries. Severity of WRHIs was significantly associated with sources of injury and sectors of industry.
    Study site: emergency room, orthopaedic ward, general surgery ward and the orthopaedic outpatient clinic of a tertiary hospital
    Matched MeSH terms: Hand Injuries
  4. Wang Y, Li Y, Yang Y, Peng C, Fu X, Gu X, et al.
    Exp Ther Med, 2020 Jul;20(1):543-549.
    PMID: 32537012 DOI: 10.3892/etm.2020.8728
    The aim of the present study was to analyze the sequence of the VP1 gene in enterovirus 71 (EV71) isolates and to explore their genetic evolution, so as to provide a scientific basis for the clinical prevention and treatment of hand, foot and mouth disease. The fecal samples of 590 patients with suspected hand, foot and mouth disease treated at Yan'an Hospital (Kunming, China) between January 2015 and December 2016 were collected and EV71 nucleic acid was detected by fluorescence PCR. The viral RNA of EV71-positive samples was extracted, the VP1 gene was amplified by PCR and the products were sequenced. The VP1 gene sequence was analyzed using DNAMAN and MEGA (version 4.0) software and homologous modeling was performed using Pymol software. A total of 50 EV71-positive samples were identified and the detection rate was 8.47% (50/590 cases). All of the 50 EV71 strains were of the C4 subtype. The genetic distance between the strains detected in the present study and EV71 strains detected in Beijing, Anhui and Malaysia was 0.01-0.03, while that between the strains detected in the present study and Australian strains was 2.11. Homologous modeling indicated that the amino acid sequence of the VP1 gene of the detected strains had a H144Y mutation. There was no significant genetic variation in the EV71 strain within the 2-year period. In conclusion, the EV71 strains detected in the present study was similar to that detected in Beijing, Anhui and Malaysia but different to that from Australia. A point mutation was present in the amino acid sequence of the VP1 gene.
    Matched MeSH terms: Hand, Foot and Mouth Disease
  5. Hashim NA, Abd Razak NA, Gholizadeh H, Abu Osman NA
    JMIR Serious Games, 2021 Feb 04;9(1):e17017.
    PMID: 33538698 DOI: 10.2196/17017
    BACKGROUND: Brain plasticity is an important factor in prosthesis usage. This plasticity helps with brain adaptation to learn new movement and coordination patterns needed to control a prosthetic hand. It can be achieved through repetitive muscle training that is usually very exhausting and often results in considerable reduction in patient motivation. Previous studies have shown that a playful concept in rehabilitation can increase patient engagement and perseverance.

    OBJECTIVE: This study investigated whether the inclusion of video games in the upper limb amputee rehabilitation protocol could have a beneficial impact for muscle preparation, coordination, and patient motivation among individuals who have undergone transradial upper limb amputation.

    METHODS: Ten participants, including five amputee participants and five able-bodied participants, were enrolled in 10 1-hour sessions within a 4-week rehabilitation program. In order to investigate the effects of the rehabilitation protocol used in this study, virtual reality box and block tests and electromyography (EMG) assessments were performed. Maximum voluntary contraction was measured before, immediately after, and 2 days after interacting with four different EMG-controlled video games. Participant motivation was assessed with the Intrinsic Motivation Inventory (IMI) questionnaire and user evaluation survey.

    RESULTS: Survey analysis showed that muscle strength and coordination increased at the end of training for all the participants. The results of Pearson correlation analysis indicated that there was a significant positive association between the training period and the box and block test score (r8=0.95, P

    Matched MeSH terms: Hand
  6. Dorai AA, Halim AS, Zulmi W
    Med J Malaysia, 2004 Dec;59 Suppl F:42-6.
    PMID: 15941160
    Reconstructive surgeons often encounter complex soft tissue and skeletal defects following oncological surgery. Soft tissue defects after wide resection in upper extremities posses a difficult challenge to find adequate tissue for reconstructing these defects. Paucity of local tissues dictates the requirement of loco-regional or distant flaps for these complex soft tissue defects which often exposes tendons, bones, nerves and joints. The latissimus dorsi muscle is a near ideal flap for the reconstruction because of the long neurovascular pedicle, ease of mobilization and its expendability. It can be rotated, with or without overlying skin, to cover soft tissue defects of the shoulder arm and elbow. Due to the large size of the muscle, it can be used to resurface the soft tissue defects and cover all major structures. Eleven consecutive cases were reviewed in which latissimus dorsi myocutaneous flap was used to reconstruct soft tissue defects of the upper limb following radical tumor resection. Flap survival was 100% with nominal donor site morbidity.
    Matched MeSH terms: Hand/surgery*
  7. Shipra P, Srijit D
    Acta Medica (Hradec Kralove), 2007;50(3):213-215.
    PMID: 28795947 DOI: 10.14712/18059694.2017.85
    Abductor pollicis longus (APL) muscle is known to exhibit different variations with respect to its attachments. Various studies have reported the splitting of the APL muscle. Comparative anatomical findings of split insertion of APL is commonly found in chimpanzees, gorillas and gibbons. In the present study, we describe an anomalous APL muscle, which originated from the posterior surface of the shaft of the radius and ulna and traversed a course deep to the extensor retinaculum. Interestingly, immediately after emerging form the deeper aspect of extensor retinaculum, the thin tendon of the APL muscle continued again as a muscular belly in relation to the dorsolateral part of the 1st metacarpal bone, to end as a tendon with its attachment to the base of the proximal phalanx. Such an unusual variation of APL with its attachment into proximal phalanx is a rare finding and may be of importance in altering the mechanics of the thumb during abduction. The clinical significance of such an anatomical variation of APL may be important during reconstructive surgeries involving thumb and also of academic interest.
    Matched MeSH terms: Hand
  8. Ezrin Hani Sukadarin, Baba Md Deros, Jaharah A. Ghani, Ahmad Rasdan Ismail, Nur Syazwani Mohd Nawi, Norhidayah Abdull
    MyJurnal
    Validity test is important during the development of ergonomics measurement. Failure to conduct validity tests will result in the measurement method being developed to be incapable of providing reliable ergonomics measurements. The objective of this study is to conduct validity test on the simple method ergonomics measurement which was developed. The method named Simple Ergonomics Risks Assessment (SERA). Content validity test and criterion validity test were conducted. The content validity test consists of 6 ergonomics experts who actively provide inputs and positive feedbacks to improve the measurement method being developed. Meanwhile, the criterion validity test involves data collection of complaints on body parts among oil palm workers which were derived from Nordic Musculoskeletal Questionnaire (NMQ) and ergonomics risk assessment scores obtained from SERA. Both findings were tested with the Chi-square test to explore possible relations between the two findings. Results from the test conducted showed that there are significant relations in the scores of neck posture; hip, right and left shoulder, right and left wrists and the right hand associated with fresh fruit bunch (FFB) harvesting activities. In the loose fruits collection, the Chi-square test showed significant relations in the scores of neck posture, hip, right and left shoulders, right wrist, right arm and the left hand. However, there are body parts such as the legs which showed no significant relation. More tests should be conducted to further explore the validity of the method being developed. Findings from both validity tests show that SERA were verified by the experts and tested with validated method so that it is valid to be applied in the future.
    Matched MeSH terms: Hand
  9. Wan Hassan WN, Abu Kassim NL, Jhawar A, Shurkri NM, Kamarul Baharin NA, Chan CS
    Am J Orthod Dentofacial Orthop, 2016 Apr;149(4):567-78.
    PMID: 27021461 DOI: 10.1016/j.ajodo.2015.10.018
    In this article, we present an evaluation of user acceptance of our innovative hand-gesture-based touchless sterile system for interaction with and control of a set of 3-dimensional digitized orthodontic study models using the Kinect motion-capture sensor (Microsoft, Redmond, Wash).
    Matched MeSH terms: Hand
  10. Murukesu RR, Singh DKA, Shahar S
    BMC Public Health, 2019 Jun 13;19(Suppl 4):529.
    PMID: 31196015 DOI: 10.1186/s12889-019-6870-6
    BACKGROUND: Urinary incontinence (UI) is known to be more prevalent among women and is associated with decline in quality of life. The aim of our study was to investigate the prevalence, risk factors of urinary incontinence and its impact on quality of life among community dwelling older women living in urban and rural populations.

    METHODS: This study was conducted based on secondary data analysed from the third phase of the longitudinal study "Neuroprotective Model for Health Longevity among Malaysian Elderly" (LRGS TUA). Stratification of urban and rural study areas were in accordance to that determined by the Department of Statistics. A total of 814 community dwelling older women (53% urban, 47% rural), aged 60 years and above, across four states within Peninsular Malaysia were included in this analysis. Interview-based questionnaires were used to obtain respondents' sociodemographic details and clinical characteristics. The Timed Up and Go test and Handgrip Strength tests were used to assess physical function. Urinary incontinence was self-reported, and quality of life of those with incontinence was assessed using the King's Health Questionnaire (KHQ).

    RESULTS: Prevalence of urinary incontinence was 16% and 23% among older women living in urban and rural areas, respectively. Ethnicity was significantly associated with incontinence among older women in both urban and rural population (p 

    Matched MeSH terms: Hand Strength
  11. Liew SK, Shim BJ, Gong HS
    Korean J Neurotrauma, 2020 Oct;16(2):126-137.
    PMID: 33163420 DOI: 10.13004/kjnt.2020.16.e48
    Cervical spinal cord injury (SCI) often causes debilitating loss of function of the upper limb. Upper extremity reconstruction surgery can restore some of the upper limb function in tetraplegic patients with SCI. The procedures are typically muscle-tendon unit transfer surgeries, which redistribute the remaining functional muscles to restore active elbow extension, key grip, and finger grasping. In addition to the tendon transfer surgeries, nerve transfers have emerged recently and are showing promising results. However, despite more than half of the tetraplegic patients can benefit from upper limb surgery, only a few of them receive the procedures. This missed opportunity may be due to the lack of communication between SCI specialists and hand surgeons, or the lack of awareness of such options among the specialists and patients. In this review, we provide a basic overview of upper limb reconstruction in tetraplegic patients with target audience of SCI specialists for their better understanding of the basic concept of surgery and information for patient consultation before referring to hand surgeons.
    Matched MeSH terms: Hand; Hand Strength
  12. Murty OP
    Am J Forensic Med Pathol, 2008 Jun;29(2):167-9.
    PMID: 18520487 DOI: 10.1097/PAF.0b013e318177ea88
    Electrocution is one of the rarest modes of suicide. In this case, one school going adolescent committed suicide by electrocution using bare electric wire. This is a rare case of suicidal death by applying live wires around the wrists, simulating the act of judicial electrocution. He positioned himself on armed chair and placed the nude wire loops from a cable around both wrists and switched on the current by plugging in to nearest socket by foot. There were linear electric contact wounds completely encircling around the both wrists. In addition to these linear electric burns all around wrists, there were electrical burns over both hands. This death highlights the need of supervision and close watch on children for self-destructing activities and behavior. This case also highlights unusual method adopted by adolescent to end his life.
    Matched MeSH terms: Hand Injuries/pathology
  13. Tay YG, Tan KK
    Burns, 1996 Aug;22(5):409-12.
    PMID: 8962663
    Six hands from five patients were seen with full-thickness burns following a ritual practice between June 1993 and June 1994. Three hands were treated with excision and medium-thickness split-skin grafts, one patient was treated with a medium-thickness split skin graft taken from the instep of the foot. The first patient with bilateral burns of the palms refused surgery and returned 3 months later with contractures of the palms. The results of the treated hands are presented.
    Matched MeSH terms: Hand Injuries/etiology*
  14. Fong MY, Wong KT, Rohela M, Tan LH, Adeeba K, Lee YY, et al.
    Trop Biomed, 2010 Dec;27(3):447-50.
    PMID: 21399585 MyJurnal
    We report a case of unusual cutaneous toxoplasmosis manifestation in a HIV-positive patient. He presented with hard and painful nodular lesions on the arms, hands and chest. Serology tests for anti-Toxoplasma antibody were negative. However, histopathologic examination of the lesion revealed foci of macrophages containing crescent-shaped organisms resembling the zoites of the protozoan parasite Toxoplasma gondii. Ultrastructure examination under electron microscopy and PCR confirmed the organism as T. gondii.
    Matched MeSH terms: Hand/pathology
  15. Segaran Ramodran, Billy Bryan Jafrin, Mellonna Ignatia Jeffrey Liew, Nurul MadihahMohd Raeh, Juecella Joyce Jalius
    MyJurnal
    Introduction: EC1773 is a community outreach program conducted annually by Universiti Malaysia Sabah (UMS). It serves as a platform for nursing and medical students to collaborate hands-on health promotion for rural commu- nities. As of date, there has been no empirical study to gauge student`s post-program satisfaction. This study aims to evaluate satisfaction among students who have undergone the UMS-led community out-reach program and identify gaps for improvement. Methods: The study entailed a cross-sectional design involving 165 (N) nursing(n=65) and medical students (n=100) who had completed a 10-day rural outreach program. Ethical approval was obtained from the Research Ethics Committee of UMS as well-informed consent from respondents. A 25- item questionnaire requir- ing Likert-scale responsewas used to evaluatethe level of satisfaction across 5 sub-categories namely; pre-departure preparation & briefing;onsite facilities and logistics; teamwork; community participation and learning achievements. Results: Among 165 nursing -medical students in the study, 88% (n=146) were satisfied and 12% (n=19) were dis- satisfied with the UMS-led outreach program. Sub-category items rated as satisfactory were community participation 96% and learning achievements 91%. Poor satisfaction highlighted by respondents regarding the out-reach program were inadequacy of facilities and poor logistics 62% and quality of pre-departure preparation and briefing 66%. Nursing students reported significantly higher dissatisfaction (p=0.04) regarding teamwork and adequacy of onsite facilities and logistics. Conclusion: Findings from this study infers that student’s post-evaluation towards the UMS-led outreach is generally satisfactory but has specific shortfalls that need to be addressed.
    Matched MeSH terms: Hand
  16. Wan Yusoff WR, Hanafi MH, Ibrahim AH, Kassim NK, Suhaimi A
    J Taibah Univ Med Sci, 2021 Apr;16(2):288-291.
    PMID: 33897336 DOI: 10.1016/j.jtumed.2020.12.003
    Alien hand syndrome (AHS) is a rare post-stroke complication. Although the occurrence of AHS after stroke is rare, it can have a disabling impact on the lifestyle and career of the patients post stroke. It is difficult to distinguish AHS from the non-dominant hemispheric infarction with symptoms of hemianopia and left hemineglect, as patients with AHS can also have neglect as well as behaviour symptoms if the frontal lobe is involved. We report the case of a 62-year-old gentleman who was admitted to the rehabilitation ward and was treated for neglect and apraxia following right middle cerebral artery stroke. After further re-evaluation, the patient was diagnosed with AHS. Functionally, he improved and the symptoms disappeared four months after the stroke. In this case report, we highlight the features of AHS and provide a unique management approach.
    Matched MeSH terms: Hand; Alien Hand Syndrome
  17. Patricia Sator, Mezi Marcella Madius, Magdlin Sargius, Bertsy Deborah Louis, Grace Shirley Randy
    MyJurnal
    Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a bacteria or germ which many people carry in their nose or on their skin and it is resistant to a range of antibiotics including methicillin. The primary mode of transmission of S. aureus is by direct contact usually, skin-to-skin contact, although contact with contaminated objects and surfaces or might also play a role. The risk of infection by antibiotic-resistant organisms is a common problem in a hospital setting. When it comes to caring for the patient with an infectious disease such as MRSA, most nursing students tried to avoid caring for the patient because they fear of getting infected. So, in this regards that it is important to find out the perception of nursing students towards MRSA patients. Methods: This study is a descriptive cross-sectional study design and a structured questionnaire used to evaluate the perception among student nurses regarding care for a patient with MRSA. The population of this study consists only of the nursing student of year 2 and year 3, which is 118 students. A minimum of 60 respondents selected by convenient sampling from this population. Results: Findings showed the respondent’s perception towards MRSA patients that 83.55% (n=55) of the respondent has the feeling of avoiding getting close to MRSA patients. While 16.7% (n=11) did not have the feeling to avoid them. 47% (n=31%) respondents felt refused to do any procedure on MRSA patients. While 53% (n=35) did not feel refuse to do any procedure on MRSA patient. 92.4% (n=61) respondents wear full PPE before caring for patients with MRSA. The other 7.6% (n=5) did not wear full PPE before caring for patients with MRSA. 98.5% (n=65) respondents always follow 5 moments of hand hygiene. While the other 1.5% (n=1) did not always follow 5 moments of hand hygiene. Conclusion: To conclude, even though most of the respondents know about MRSA but some of them did not know that MRSA is curable or not, some confusion about the mode of transmission of MRSA and did not know that they should wear full PPE in caring for the patient with MRSA. Lack of knowledge about MRSA might influence them to ask their friends to do procedures for the patient instead of doing it by themselves. Without good knowledge and skills about how to handle infectious patients, it is difficult for the nursing students to approach the patient with an infectious disease such as MRSA.
    Matched MeSH terms: Hand Hygiene
  18. Sivasamy P, Bajuri MY, Ghani AW
    Cureus, 2019 Nov 19;11(11):e6203.
    PMID: 31890405 DOI: 10.7759/cureus.6203
    The incidence of wrist tuberculosis is rare. Clinical features and radiographs are not conclusive in the beginning, happen to delay the achievement of the diagnosis, and thus result in poor treatment. We present a case report of wrist tuberculosis that had delayed diagnosis. Hence, the initiation of antituberculous treatment was delayed, as the initial investigations were not conclusive of tuberculous infection. The patient was treated surgically multiple times before tuberculosis was diagnosed. Antituberculous chemotherapy was started for the patient for one year until she became afebrile and infective markers returned to normal. However, the patient developed left wrist stiffness due to arthrofibrosis and bony destruction of the wrist joint.
    Matched MeSH terms: Hand Joints
  19. METHA KM
    Med J Malaya, 1955 Jun;9(4):284-7.
    PMID: 13253129
    Matched MeSH terms: Hand*; Hand Injuries*
  20. Md Rezali KA, Griffin MJ
    Ergonomics, 2018 Sep;61(9):1246-1258.
    PMID: 29628001 DOI: 10.1080/00140139.2018.1462407
    This study investigated effects of applied force on the apparent mass of the hand, the dynamic stiffness of glove materials and the transmission of vibration through gloves to the hand. For 10 subjects, 3 glove materials and 3 contact forces, apparent masses and glove transmissibilities were measured at the palm and at a finger at frequencies in the range 5-300 Hz. The dynamic stiffnesses of the materials were also measured. With increasing force, the dynamic stiffnesses of the materials increased, the apparent mass at the palm increased at frequencies greater than the resonance and the apparent mass at the finger increased at low frequencies. The effects of force on transmissibilities therefore differed between materials and depended on vibration frequency, but changes in apparent mass and dynamic stiffness had predictable effects on material transmissibility. Depending on the glove material, the transmission of vibration through a glove can be increased or decreased when increasing the applied force. Practitioner summary: Increasing the contact force (i.e. push force or grip force) can increase or decrease the transmission of vibration through a glove. The vibration transmissibilities of gloves should be assessed with a range of contact forces to understand their likely influence on the exposure of the hand and fingers to vibration.
    Matched MeSH terms: Hand/physiology*; Hand Strength
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