Displaying publications 181 - 200 of 239 in total

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  1. Cunningham IG, Yong NK
    Br J Surg, 1974 Jun;61(6):482-3.
    PMID: 4835202
    Matched MeSH terms: Iodine Radioisotopes
  2. Muhamat Omar, Zalina Laili, Mohd Suhaimi Hamzah
    MyJurnal
    Qualitative and quantitative analysis of samples require good judgment from the analysts. These two aspects in gamma spectrometric analysis of Proficiency Test and solid radioactive waste samples for the determination of radionuclides are discussed. It is vital to judge and decide what energy peaks belong to which radionuclides prior to the creation of customized radionuclide library for the analysis of specific samples. Corrections due to radionuclide decay and growth, and the half-life assigned to a particular radionuclide in the uranium and thorium series are also discussed. Discussion on judgment to confirm the presence of thorium in food samples based on gamma spectrometry and neutron activation analysis is also provided.
    Matched MeSH terms: Radioisotopes
  3. Zainuddin Z, Shaker AAH
    Family Physician, 2005;13(3):2-4.
    MyJurnal
    Thyroid diseases are common in women, including at the time of pregnancies. Many typical features of hyperthyroidism are common in normal pregnancies and this may delay or mask the diagnosis. Uncontrolled thyrotoxicosis increases the rate of miscarriage, intrauterine growth restriction (IUGR), premature labour and perinatal mortality. Multi-disciplinary efforts are required to achieve optimal control of thyrotoxicosis. Anti-thyroid drugs are safe and should be used with the lowest possible doses. Radioiodine treatment is contraindicated during pregnancy and lactation. Indications of surgery include: compression symptoms, thyroid malignancy, non-compliance to medications or when the patient develop drugs side effects
    Matched MeSH terms: Iodine Radioisotopes
  4. Rohyiza Ba’an, Zalina Laili, Mohd Abdul Wahab Yusof, Muhamat Omar
    MyJurnal
    Feasibility studies on the vitrification of spent ion exchange resins combined with glass cullet powder have been conducted using a High Temperature Test Furnace. Bottle glass cullet powder was used as matrix material to convert the ash of the spent resins into a glass. Vitrificat ion of spent ion exchange resins presents a reasonable disposal alternative, because of its inherent organic destruction capabilities, the volume reduction levels obtainable, and the durable product that it yields. In this study, the spent ion exchange resin from the PUSPATI TRIGA reactor of Nuclear Malaysia was combusted in a lab scale combustor and the resulting ash was vitrified together with glass cullet powder in a high temperature furnace to produce a stable spent resin ash embedded in glass. The factors affecting this immobilized waste, such as thermal stability, radiological stability and leachability have all been investigated. However, the outcome of these tests, which include the radionuclide activity concentration in the slag, the optimum conditioning temperature - in relation with volume reduction during vitrification - and the volume mixing ratio of matrix material were reported. It was found that the radionuclides present in spent resins were 54 Mn, 60 Co and 152Eu. The elementary chemical composition (carbon, hydrogen, nitrogen and sulphur) of spent resins was 27.6% C, 5.68% H, 2.04% N and 4.20% S, respectively. The maximum calorific value of spent resins was 1735 kJ/kg. The average activity concentrations of 54 Mn and 60Co in ash at 200oC were 9,411 ± 243 Bq/Kg and 12,637± 201 Bq/Kg. flue gases containing CO2, CO, SO2 and NO started to be emitted above 200oC. The optimum conditioning temperature was also the highest tested, i.e. 900oC in 45 minutes, and the best mixing ratio ash to matrix material was also the highest, ie 1:9. Finally, the leaching analysis of slag at 900oC in 45 minutes showed that the leaching activity of 60Co was below 0.5 Bq/mL.
    Matched MeSH terms: Radioisotopes
  5. Zaini Hamzah, Marlinda Musa, Ahmad Saat
    MyJurnal
    There are many essential and non-essential elements including metals and radionuclides present in vegetables. Howeve r, the accumulation of the several metals and radionuclides might cause the contamination to vegetables itself. Green m ustard (Brasissca rapa var. Parachinesis L.) was selected to represent the vegetable in this study. Objectives of this stud y are to determine the concentration of metals and radionuclides in the samples and to calculate the enrichment factor ( EF) and also to estimate the uptake, base on biological accumulation coefficient (BAC), for the various parts of selecte d vegetables. Three farmlands in the Cameron Highlands were studied namely Bharat, Kg Raja and Bertam area. The g reen mustard and soil samples were collected during the harvest season. Samples were dried, ground and sieved prior t o analysis. Analyses for both samples were done by using X-rays Fluorescence Spectroscopy (XRF) to measure the conc entration of Fe, Zn, Hg, U and Th. The concentration of all elements in the soils is lower than their concentration in the control soil, except for Zn, U and Th. The concentration of all elements in Green Mustard is lower than their concentrat ion in the soil where it was grown. The EF values in the Brasissca rapa var. Parachinesis L are lower than 2 except for U and Th, indicating some degree of contamination due to anthropogenic activities or naturally origin. The BAC values show that Zn and Hg were accumulated in the green mustard, depending on where the plant grows.
    Matched MeSH terms: Radioisotopes
  6. Ahmad Saat, Nurulhuda Kassim, Zaini Hamzah, Ahmad Farisz
    MyJurnal
    Taman Negara is a famous tourism destination for nature lover in Malaysia. The area is well kept from human activities and disturbances. Since there is no data for human exposure to natural radiation, there is a need to do this study. It will give a baseline data for surface dose and radionuclide concentrations and one can estimate the external hazards index for the visitor to this unexplored area, i.e. UiTM-Perhilitan research station, Kuala Keniam, Taman Negara, Malaysia. The surface dose rate measurements were done in-situ using portable radiation survey meter at the surface and 1 m above the surface. The top soil samples were taken using hand auger up to 15 cm depth at nine locations around research station. Samples were brought back to the UiTM laboratory in Shah Alam, dried, ground to powder form, and sieved using 250 μm sieve. Then the uranium and thorium concentrations were analyzed using Energy Dispersive X-Ray Fluorescence (EDXRF).The mean value for surface dose rates on surface were 0.164 μSv/hr while the mean value for surface dose rates on 1m above the surface were 0.161 μSv/hr. The mean concentration of thorium was 2.62μg/g while the mean concentration of uranium was 0.61μg/g.
    Matched MeSH terms: Radioisotopes
  7. Zaini Hamzah, Che Yasmin Amirudin, Seh Datul Riduan, Ahmad Saat
    MyJurnal
    137 Cs is well known man-made radionuclide produced from nuclear industry. Nuclear weapon tests and nuclear accidents had contributed to presence of 137 Cs into the worldwide environment including Malaysia. It has spread out to the entire world through the air and water current. Since Cameron Highlands is located at high altitude, there is a better chance of the 137 Cs to settle down on the trees and later the soil underneath. In this study, the soil samples were taken at the slopes of two different tea plantation areas namely A and B. The soil samples were oven dried, ground, sieved and packed and sealed properly in plastic containers before measurement. Each plastic container contains around 450 g of sample. The measurement of 137 Cs activity concentration was done using HPGe detector gamma spectrometer. The spectrum was analyzed using Gamma Vision software to calculate the activity concentration of 137 Cs with energy peak of 661.66 keV. The activity concentration of 137 Cs found in the samples ranged from 0.23 to 1.90 and 0.11 to 3.01 Bq/kg for tea plantation A and tea plantation B, respectively. From the activity concentration of 137 Cs result, it was comparable to the others research regarding to 137 Cs in the soil around Asian.
    Matched MeSH terms: Cesium Radioisotopes
  8. Olatunji MA, Khandaker MU, Amin YM, Mahmud HN
    PLoS One, 2016;11(10):e0164119.
    PMID: 27706232 DOI: 10.1371/journal.pone.0164119
    A radiotracer study was conducted to investigate the removal characteristics of cadmium (109Cd) from aqueous solution by polypyrrole/ sawdust composite. Several factors such as solution pH, sorbent dosage, initial concentration, contact time, temperature and interfering metal ions were found to have influence on the adsorption process. The kinetics of adsorption was relatively fast, reaching equilibrium within 3 hours. A lowering of the solution pH reduced the removal efficiency from 99.3 to ~ 46.7% and an ambient temperature of 25°C was found to be optimum for maximum adsorption. The presence of sodium and potassium ions inhibited 109Cd removal from its aqueous solution. The experimental data for 109Cd adsorption showed a very good agreement with the Langmuir isotherm and a pseudo-first order kinetic model. The surface condition of the adsorbent before and after cadmium loading was investigated using BET, FESEM and FTIR. Considering the low cost of the precursor's materials and the toxicity of 109Cd radioactive metal, polypyrrole synthesized on the sawdust of Dryobalanops aromatic could be used as an efficient adsorbent for the removal of 109Cd radioisotope from radionuclide-containing effluents.
    Matched MeSH terms: Cadmium Radioisotopes
  9. Bradley, Sani SFA, Shafiqah ASS, Collins SM, Hugtenburg RP, Rashid HAA, et al.
    Appl Radiat Isot, 2018 Aug;138:65-72.
    PMID: 28427834 DOI: 10.1016/j.apradiso.2017.04.019
    Using tailor-made sub-mm dimension doped-silica fibres, thermoluminescent dosimetric studies have been performed for α-emitting sources of 223RaCl2 (the basis of the Bayer Healthcare product Xofigo®). The use of 223RaCl2 in the palliative treatment of bone metastases resulting from late-stage castration-resistant prostate cancer focuses on its favourable uptake in metabolically active bone metastases. Such treatment benefits from the high linear energy transfer (LET) and associated short path length (<100µm) of the α-particles emitted by 223Ra and its decay progeny. In seeking to provide for in vitro dosimetry of the α-particles originating from the 223Ra decay series, investigation has been made of the TL yield of various forms of Ge-doped SiO2 fibres, including photonic crystal fibre (PCF) collapsed, PCF uncollapsed, flat and single-mode fibres. Irradiations of the fibres were performed at the UK National Physical Laboratory (NPL). Notable features are the considerable sensitivity of the dosimeters and an effective atomic number Zeff approaching that of bone, the glass fibres offering the added advantage of being able to be placed directly into liquid. The outcome of present research is expected to inform development of doped fibre dosimeters of versatile utility, including for applications as detailed herein.
    Matched MeSH terms: Radioisotopes
  10. Jamalludin Z, Malik RA, Ung NM
    Phys Eng Sci Med, 2021 Sep;44(3):773-783.
    PMID: 34191272 DOI: 10.1007/s13246-021-01026-x
    Intracavitary cervical brachytherapy delivers high doses of radiation to the target tissue and a portion of these doses will also hit the rectal organs due to their close proximity. Rectal dose can be evaluated from dosimetric parameters in the treatment planning system (TPS) and in vivo (IV) dose measurement. This study analyzed the correlation between IV rectal dose with selected volume and point dose parameters from TPS. A total of 48 insertions were performed and IV dose was measured using the commercial PTW 9112 semiconductor diode probe. In 18 of 48 insertions, a single MOSkin detector was attached on the probe surface at 50 mm from the tip. Four rectal dosimetric parameters were retrospectively collected from TPS; (a) PTW 9112 diode maximum reported dose (RPmax) and MOSkin detector, (b) minimum dose to 2 cc (D2cc), (c) ICRU reference point (ICRUr), and (d) maximum dose from additional points (Rmax). The IV doses from both detectors were analyzed for correlation with these dosimetric parameters. This study found a significantly high correlation between IV measured dose from RPmax (r = 0.916) and MOSkin (r = 0.959) with TPS planned dose. The correlation between measured RPmax with both D2cc and Rmax revealed high correlation of r > 0.7, whereas moderate correlation (r = 0.525) was observed with ICRUr. There was no significant correlation between MOSkin IV measured dose with D2cc, ICRUr and Rmax. The non-significant correlation between parameters was ascribable to differences in both detector position within patients, and dosimetric volume and point location determined on TPS, rather than detector uncertainties.
    Matched MeSH terms: Cobalt Radioisotopes
  11. Rohani MFM, Zanial AZ, Nagaratnam P, Gew LT, Mutalib NAA, Hassan SZA
    Med J Malaysia, 2021 07;76(4):518-525.
    PMID: 34305113
    INTRODUCTION: Gastroparesis is a medical condition that can cause significant morbidity. Its prevalence in Malaysia is not known and is often under diagnosed. The gold standard in the assessment of gastroparesis is radionuclide gastric emptying scintigraphy (GES). The aim of this study was to evaluate the added benefit of performing GES in patients with suspected gastroparesis in Hospital Kuala Lumpur (HKL).

    METHODS: The clinical data and scintigraphic findings of consecutive patients referred to the Department of Nuclear Medicine, HKL for GES from July 2020 to December 2020 were retrospectively reviewed.

    RESULTS: Thirteen patients underwent the study (6 males and 7 females) with a mean age of 47.9 years (age range of 25 to 72 years). The majority of patients (n=11) were diagnosed with either type I or type II diabetes mellitus. Ten patients reported abnormal scan findings with only 3 patients had normal GES findings. Scintigraphic findings from our patients, association of symptoms with abnormal GES as well as the challenges in implementing GES in Malaysia is discussed.

    CONCLUSION: GES provides valuable information to the referring physician in the diagnosis and management of patients with gastric motility disorders. However, its use is limited because of limited availability, cost restriction, lack of familiarity among clinicians, and lack of understanding of the test. Further effort is thus needed to enhance the availability and usage of GES in Malaysia.

    Matched MeSH terms: Radioisotopes
  12. Ahmed, Moussa Mohamed, Nik Rashida Nik Abdul Ghani, Jami, Mohammed Saedi, Mirghani, Mohamed Elwathig Saeed, Md. Noor Salleh
    MyJurnal
    Boron has been classified as a drinking water pollutant in many countries. It is harmful to many plants, exceptionally sensible plants, and human health. Therefore, boron level needs to be decreased to 0.3 mg/L for drinking water and within 0.5 mg/L to 1 mg/L for irrigation water. In this study, various operational parameters namely pH, contact time and liquid/solid ratio were investigated to determine the potential of using date seed (or date pit or date stone) to remove boron from seawater. This study's main objective was to determine boron adsorption capacities of date seeds prepared by various methods (i.e., powdered, activated, acid-treated and defatted seed) by batch adsorption process using boron contaminated synthetic seawater. The process parameters of the selected biosorbent among the four date seed preparations methods were optimized. The surface characteristics were analyzed by using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscope (SEM). The results showed that acid-treated date seed was the best biosorbent in terms of removing 89.18% boron from aqueous solution at neutral pH, liquid to solid ratio of 5 within 2 hours of reaction time at room temperature (25°C±2°C).
    Matched MeSH terms: Radioisotopes
  13. Salah H, Al-Mohammed HI, Mayhoub FH, Sulieman A, Alkhorayef M, Abolaban FA, et al.
    Radiat Prot Dosimetry, 2021 Oct 12;195(3-4):349-354.
    PMID: 34144608 DOI: 10.1093/rpd/ncab077
    This study has sought to evaluate patient exposures during the course of particular diagnostic positron emission tomography and computed tomography (PET/CT) techniques. A total of 73 patients were examined using two types of radiopharmaceutical: 18F-fluorocholine (FCH, 48 patients) and 68Ga-prostate-specific membrane antigen (PSMA, 25 patients). The mean and range of administered activity (AA) in MBq, and effective dose (mSv) for FCH were 314.4 ± 61.6 (462.5-216.8) and 5.9 ± 1.2 (8.8-4.11), respectively. Quoted in the same set of units, the mean and range of AA and effective dose for 68Ga-PSMA were 179.3 ± 92.3 (603.1-115.1) and 17.9 ± 9.2 (60.3-11.5). Patient effective doses from 18F-FCH being a factor of two greater than the dose resulting from 68Ga-PSMA PET/CT procedures. CT accounts for some 84 and 23% for 18F-FCH and 68Ga-PSMA procedures, accordingly CT acquisition parameter optimization is recommended. Patient doses have been found to be slightly greater than previous studies.
    Matched MeSH terms: Gallium Radioisotopes
  14. Mohd Rohani MF, Amir Hassan SZ
    Clin Nucl Med, 2022 Jan 01;47(1):e20-e22.
    PMID: 34028418 DOI: 10.1097/RLU.0000000000003698
    A 57-year-old woman was referred for radioactive iodine therapy 12 weeks after completion thyroidectomy and left modified radical neck dissection for pT2N1Mx follicular variant papillary thyroid carcinoma. After 4 weeks of l-thyroxine withdrawal, stimulated serum thyroglobulin level was less than 0.1 ng/mL with positive thyroglobulin antibody. Posttherapy 131I scintigraphy with SPECT/CT of the head and abdominopelvic region showed thyroid residual in the neck, occipital bone metastasis, and heterogenous tracer uptake in a large peritoneal mass, likely arising from the left ovary. Left salpingo-oophorectomy was performed, and histopathologic examination revealed endometrioid carcinoma of left ovary.
    Matched MeSH terms: Iodine Radioisotopes
  15. Vijayananthan A, Arumugam A, Kumar G, Harichandra D
    Biomed Imaging Interv J, 2008 Apr;4(2):e23.
    PMID: 21614326 MyJurnal DOI: 10.2349/biij.4.2.e23
    Atypical mycobacterium is rarely seen as a cause of chronic mastoiditis but has been increasingly recognized over the past few years. Mycobacterium abscessus is the most pathogenic and chemotherapy-resistant, rapid-growing mycobacterium of all the four groups. This paper presents a case of a 57-year-old woman who had chronic mastoiditis with recurrent exacerbations. The initial computed tomography (CT) findings showed the presence of an inflammatory process and she was treated with the appropriate antibiotics. The patient subsequently underwent a tissue biopsy when she presented with another exacerbation. At this time, the CT scan did not identify the ongoing exacerbation, but the Gallium-67 scintigraphy did.
    Matched MeSH terms: Gallium Radioisotopes
  16. Yeong CH, Blackshaw PE, Ng KH, Abdullah BJ, Blaauw M, Dansereau RJ, et al.
    Appl Radiat Isot, 2011 Sep;69(9):1181-4.
    PMID: 21550260 DOI: 10.1016/j.apradiso.2011.04.017
    Neutron activation of Sm-152 offers a method of radiolabeling for the in vivo study of oral dose formulations by gamma scintigraphy. Reproducibility measurements are needed to ensure the robustness of clinical studies. 204 enteric-coated guaifenesin core tablets (10mg of Sm(2)O(3)) were irradiated by thermal neutrons to achieve 1 MBq at 48 h. Administered activities were 0.86±0.03 MBq. Good reproducibility (CV=3.5%) was observed over 24 weeks ensuring that volunteer doses were within the dose reference level of 0.8 mSv.
    Matched MeSH terms: Radioisotopes
  17. Sundram F
    Biomed Imaging Interv J, 2006 Oct;2(4):e56.
    PMID: 21614336 MyJurnal DOI: 10.2349/biij.2.4.e56
    The incidence of thyroid cancer is low, but when it occurs, it is mainly of the papillary histopathological type. Although PET/CT has a limited role in the diagnosis, it plays a significant role in the overall post-surgery management of a patient with thyroid cancer. This follow-up role is important, especially in patients with elevated serum thyroglobulin, but negative radioiodine whole body scans. There is increasing evidence that PET/CT should be a part of routine care in the Tg positive Radioiodine scan negative patient.
    Matched MeSH terms: Iodine Radioisotopes
  18. Abd Hamid MF, Abdul Razak S, Azraai AM, Miptah HN
    Am J Case Rep, 2023 Nov 10;24:e941089.
    PMID: 37946402 DOI: 10.12659/AJCR.941089
    BACKGROUND The article discusses an unusual case of papillary thyroid carcinoma in which chronic cough and hemoptysis were the predominant symptoms. While the more common causes of hemoptysis are pulmonary in origin, extrapulmonary etiologies have been reported, including thyroid carcinoma. The clinical presentation of thyroid malignancy in this case mimics many other common disorders, such as pulmonary tuberculosis, bronchogenic carcinoma, bronchiectasis, and chronic obstructive pulmonary disease. Hence, making it challenging to suspect early when patients present to primary care. CASE REPORT A 54-year-old woman presented with a chronic cough and hemoptysis in our Primary Care Medicine Clinic. While initial assessments in the primary care medicine clinic yielded no remarkable findings, a subsequent high-resolution computed tomography scan of the thorax uncovered a thyroid lesion. Subsequent evaluation in the hospital setting included an ultrasound examination, revealing multiple thyroid nodules, and fine needle aspiration that confirmed papillary thyroid carcinoma. She underwent total thyroidectomy with central and left lateral neck dissection, complicated by left vocal cord palsy. She received 2 cycles of periodic radioactive iodine therapy and injection laryngoplasty postoperatively. There was no evidence of iodin avid disease and recurrence of hemoptysis after surgery. CONCLUSIONS This case report emphasizes the significance of considering papillary thyroid carcinoma when assessing hemoptysis in the primary care setting, as early detection and treatment of it would result in a better outcome.
    Matched MeSH terms: Iodine Radioisotopes
  19. Salem A, Khandaker MM, Mahmud K, Alsufyani SJ, Majrashi AA, Rashid ZM, et al.
    Plant Physiol Biochem, 2024 Jan;206:108295.
    PMID: 38154296 DOI: 10.1016/j.plaphy.2023.108295
    The present study was conducted to investigate the effects of Trichoderma harzianum and Bacillus thuringiensis alone or with gradual levels of NPK on photosynthesis, growth, fruit quality, aroma improvement and reduced radionuclides of key lime fruits. The lemon seedlings were treated with (T0) without fertilizers as control, (T1) 100g of NPK at 100%, (T2) 5 g of Trichoderma. harzianum at 50% + 50 g of NPK at 50%, (T3) 5 g of Bacillus thuringiensis at 50% + 50 g of NPK at 50 %, (T4) 7.5 g of Trichoderma harzianum at 75% + 25 g of NPK at 25 %, (T5) 7.5 g of Bacillus thuringiensis at 75% + 25 g of NPK at 25 %, (T6) 10 g of Trichoderma harzianum at 100 % and (T7)10 g of Bacillus thuringiensis at 100 %. The results showed that T2 increased net photosynthetic rate, stomatal conductance, transpiration rate, internal CO2 concentration, fresh and dry root biomass by 209%, 74%, 56%, 376%, 69.4% and 71.6%, while, T5 increased root volume, root length, and root tip number by 27.1%, 167%, and 67%, respectively over the control trees. The microbial treatments developed cortex, vascular cylinder and tracheal elements of the root. Fruit number, length, diameter, weight, pulp thickness, pulp/peel ratio, juice, total soluble solids (TSS), pigment contents and antioxidant activity increased significantly in the T2 treatment. Vitamin C, total phenols, total flavonoids, and total sugar content increased by 1.59-, 1.66-, 1.44- and 2.07- fold in T5 treated fruits compared to the control. The two microbes increased volatile compounds and decreased radionucleotides in the fruit, moreover, 27 identified and 2 (two) unmatched volatile compounds were identified by GCMS analysis. It is concluded that T. harzianum and B. thuringiensis with 25-50 g NPK treatments improved photosynthesis, root structure, fruit growth, fruit quality, aroma and lessened radionuclides in key lime fruits.
    Matched MeSH terms: Radioisotopes
  20. Aliyu AS, Mousseau TA, Ramli AT, Bununu YA
    Ambio, 2015 Dec;44(8):778-87.
    PMID: 26093469 DOI: 10.1007/s13280-015-0677-1
    The tin mining activities in the suburbs of Jos, Plateau State, Nigeria, have resulted in technical enhancement of the natural background radiation as well as higher activity concentrations of primordial radionuclides in the topsoil of mining sites and their environs. Several studies have considered the radiological human health risks of the mining activity; however, to our knowledge no documented study has investigated the radiological impacts on biota. Hence, an attempt is made to assess potential hazards using published data from the literature and the ERICA Tool. This paper considers the effects of mining and milling on terrestrial organisms like shrubs, large mammals, small burrowing mammals, birds (duck), arthropods (earth worm), grasses, and herbs. The dose rates and risk quotients to these organisms are computed using conservative values for activity concentrations of natural radionuclides reported in Bitsichi and Bukuru mining areas. The results suggest that grasses, herbs, lichens, bryophytes and shrubs receive total dose rates that are of potential concern. The effects of dose rates to specific indicator species of interest are highlighted and discussed. We conclude that further investigation and proper regulations should be set in place in order to reduce the risk posed by the tin mining activity on biota. This paper also presents a brief overview of the impact of mineral mining on biota based on documented literature for other countries.
    Matched MeSH terms: Radioisotopes
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