Displaying publications 4101 - 4120 of 10027 in total

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  1. Mohamed WN, Abdullah NN, Muda AS
    Malays J Med Sci, 2008 Jul;15(3):55-7.
    PMID: 22570590 MyJurnal
    We report a rare case of Arteriovenous malformation (AVM) of the scalp in a 30 year-old Malay gentleman who presented with painless forehead swelling since birth. Magnetic Resonance Imaging (MRI) and cerebral angiogram performed and the findings are discussed.
  2. Hassan Y, Awaisu A, Al-Meman AA, Aziz NA
    Malays J Med Sci, 2008 Apr;15(2):3-13.
    PMID: 22589618
    Our objectives were to discuss a general overview on the description and recognition of heparin-induced thrombocytopenia (HIT) and present a critical review of the traditional and most recent advances in its pharmacotherapy. Computerized searches were done on MEDLINE and Iowa Drug Information Service (IDIS) databases from June 2001 until June 2007 and from May 2005 until May 2007, respectively. Search terms used included 'heparin-induced thrombocytopenia', 'heparin-associated thrombocytopenia', therapeutics, HIT, HAT. We largely selected publications within the timeframe above, but did not exclude commonly referenced and highly regarded older publications. The commonly referenced published articles were obtained through manual searches derived from bibliographic citations and retrievals from the authors' personal files. Pertinent literatures (89 key articles) that were thought to have substantially contributed new information to the therapeutics of HIT within the last 6 years were identified, reviewed and presented. The following limits were used for the MEDLINE and IDIS searches: 'human', drug therapy', 'review', 'meta-analysis', 'clinical trial', and case reports. The therapeutics of HIT is rapidly evolving and needs to consider an evidence - based approach. It is imperative that practitioners be aware of the associated risk and be up-to-date with the current advances in the management of this fatal clinical condition.
  3. Khanday WA, Soon KA, Ahmed MJ, Hummadi EH
    Int J Biol Macromol, 2025 Jan;285:138301.
    PMID: 39638171 DOI: 10.1016/j.ijbiomac.2024.138301
    Chitosan (CH) and pencil clay (CL) were utilized to prepare stable epichlorohydrin cross-linked chitosan-clay hybrid beads (CCHB) for the adsorptive removal of anionic reactive black 5 (RB5) dye. Among various percentage weight ratios of chitosan/clay hybrid beads, 40 % CH-60 % CL was selected as the best adsorbent owing to its stability and removal efficiency. The pore properties of CCHB in terms of surface area, total pore volume, and average pore width were 40.33 m2/g, 0.088 cm3/g, and 86.06 Å, respectively. The adsorption behavior of RB5 on CCHB followed Langmuir and pseudo-second-order models. Thermodynamic parameters confirm the endothermic and spontaneous nature of RB5 adsorption and the regeneration studies reveal a negligible decrease in removal efficiency of CCHB after 5 adsorption-desorption cycles. The CCHB exhibited adsorption capacities of 169.49, 200.00, and 227.27 mg/g for RB5, respectively, at 30, 40, and 50 °C. The prepared chitosan-clay hybrid bead adsorbent can be efficiently applied for anionic wastewater treatment.
  4. Fitri Abdul Razak MI, Fauzi FA, Zulkefli NAM
    Iran J Public Health, 2024 Dec;53(12):2768-2778.
    PMID: 39759210
    BACKGROUND: Community Health Volunteers (CHVs) are crucial in achieving universal health coverage and vital in public health activities, including the COMBI (Communication for Behavioral Impact) approach for dengue prevention and control and assessing the performance of COMBI CHVs are essential in evaluating the program effectiveness. We aimed to measure the level of performance and determine predictors of high-performance among COMBI CHVs in Kuala Lumpur and Putrajaya.

    METHODS: A cross-sectional study was conducted in 2023 among 285 COMBI CHVs from 5 health operational zones in Kuala Lumpur and Putrajaya. The CHVs were stratified proportionately, with 45.5% of respondents randomly selected from each stratum based on their zones. Self-administered questionnaires assessed their performance level and associated factors, including training, supervision, knowledge, motivation, and job satisfaction. Chi-square and Multiple Logistic Regression tests were used to determine the factors and predictors of high-performance COMBI CHVs.

    RESULTS: The prevalence of high-performance COMBI CHVs was 59.3%, significantly associated with training factors (experience, duration, and adequacy of training), supervision factors (being supervised, supervision frequency, and encouragement from supervision), motivation and job satisfaction level. As for significant predictors, having at least one day of training (AOR=14.557), being supervised by medical personnel (AOR=4.997), having a high motivation level (AOR=5.538) and having a high job satisfaction level (AOR=4.562) were more likely to have a high-performance level.

    CONCLUSION: Training duration, supervisor background, motivation and job satisfaction can contribute to high-performance levels among COMBI CHVs, which can applied in evidence-based policies and strategies for performance improvement and more effective community healthcare delivery.

  5. Samsudin S, Chui PL, Kamar ABA, Abdullah KL
    Nurs Open, 2023 Jan;10(1):349-357.
    PMID: 36514142 DOI: 10.1002/nop2.1311
    AIM: To assess the effectiveness of the maternal kangaroo care education programme over 1 month and 3 months on the mother's perception, knowledge, perceived barriers and stress.

    DESIGN: A quasi-experimental and longitudinal study was conducted among mothers with premature infants.

    METHODS: Forty-eight mother-infant dyads were enrolled per arm in the control and experimental groups. The control group received standard routine care, while the experimental group received a maternal kangaroo care education program. Data were collected through self-administered Kangaroo Care Questionnaires. Chi-square, the general linear model and repeated measures ANOVA were used to analyse data.

    RESULTS: The demographics are a majority of Malay mothers with multipara, a caesarean delivery with prematurity. At 3 months post-intervention, the experimental group reported a significant reduction in stress, a positive perception and good knowledge towards kangaroo care implementation. The mothers' perceived barriers towards kangaroo care significantly decreased after 3 months in the experimental group.

  6. Mehat MZ, Shuid AN, Mohamed N, Muhammad N, Soelaiman IN
    J Bone Miner Metab, 2010 Sep;28(5):503-9.
    PMID: 20145960 DOI: 10.1007/s00774-010-0159-2
    Bone is a specialized connective tissue that functions as the load-bearing structure of the body. Free radicals may affect bone remodeling by regulating osteoclast activity in either the physiological or pathological condition. Vitamin E, a lipid-soluble antioxidant, has been demonstrated to offer protection against osteoporosis and to improve the bone material and structure of animal models. The aim of this study was to observe and compare the effects of alpha-tocopherol (alpha-tocopherol), delta-tocotrienol (delta-tocotrienol), and gamma-tocotrienol (gamma-tocotrienol) on the static and dynamic bone histomorphometric parameters in normal male rats. Thirty-two normal Sprague-Dawley male rats aged 3 months and weighing 200-250 g were randomly divided into four groups. The control group was supplemented with oral gavages of olive oil (vehicle), whereas the alpha-tocopherol, delta-tocotrienol, and gamma-tocotrienol groups were given oral gavages of 60 mg/kg alpha-tocopherol, delta-tocotrienol, and gamma-tocotrienol, respectively. The rats were injected twice with calcein to fluorochrome-label the bones. After 4 months of treatment, the rats were killed, and the left femurs were dissected out and prepared for bone histomorphometry. Both the static and dynamic parameters of the vitamin E-treated groups were better than those of the normal control group. Among the vitamin E-treated groups, the tocotrienol groups showed better histomorphometry results compared to the α-tocopherol group, with the γ-tocotrienol group demonstrating the best effects on both sets of parameters. We concluded that vitamin E can promote bone formation in normal rats, with gamma-tocotrienol being the most potent form of vitamin E.
  7. Shuid AN, Mehat Z, Mohamed N, Muhammad N, Soelaiman IN
    J Bone Miner Metab, 2010 Mar;28(2):149-56.
    PMID: 19779668 DOI: 10.1007/s00774-009-0122-2
    Recently, vitamin E has been found to promote the bone structure of nicotine-treated rats well above their baseline values, thus suggesting that vitamin E may have some anabolic action. A bone anabolic agent acts by improving the bone structure leading to stronger bone. To assess the possible anabolic action vitamin E on bone, we supplemented alpha-tocopherol (ATF) or gamma-tocotrienol (GTT) at 60 mg/kg or vehicle [normal control (NC) group] for 4 months to normal male rats and measured their bone structure and biomechanical properties. Histomorphometric analysis revealed that vitamin E-supplemented rats have better trabecular volume, thickness, number, and separation than rats receiving vehicle only. For the first time we reported that GTT improves all the parameters of bone biomechanical strength, while ATF only improved some of the parameters compared to the NC group. Vitamin E supplementation, especially with the gamma isomer, improves bone structure, which contributed to stronger bone. Therefore, vitamin E has the potential to be used as an anabolic agent to treat osteoporosis or as bone supplements for young adults to prevent osteoporosis in later years.
  8. Alam S, Hadian MSD, Hamdani AH, Sulaiman N
    Sci Rep, 2025 Jan 07;15(1):1099.
    PMID: 39775130 DOI: 10.1038/s41598-024-82720-0
    Accurately identifying Milankovitch cycles has been a significant challenge in cyclostratigraphic studies, as it is essential for improving geochronology. This manuscript focuses on developing a method that distinguishes Milankovitch cycles from sedimentary noise to enhance stratigraphic precision. Despite their often-conspicuous magnitude, these periodicities frequently intertwine with noise, posing a challenge for conventional spectral analysis. Therefore, to address this issue, we have developed an algorithm that enhances the resolution of the Milankovitch signal by employing convex optimization in spectral analysis. To evaluate the effectiveness of this new algorithm, we applied it to four distinct types of local stratigraphy where the Milankovitch signal has been confirmed. These include the stratigraphic sections in the middle Miocene molluscan beds of Java and the Mahakam Delta, Pleistocene sediments of Hominin Flores, and the Towuti Lake in Sulawesi Island, Indonesia. Our findings demonstrate the preservation of all targeted signals, with a confidence level surpassing 99%. By setting the significance level to 1%, we can reject the null hypothesis, which assumes noise or the absence of a Milankovitch signal in the stratigraphic data being tested. The absence of deviations from the identified periodicities further strengthens the Milankovitch signal, underscoring the robustness of our algorithm. However, we acknowledge that achieving optimal results still hinges on the accurate selection of the initial parameters z and λ.
  9. Asha'ari ZA, Suhaimi Y, Fadzil A, Zihni M
    Malays J Med Sci, 2012 Oct;19(4):84-7.
    PMID: 23613654 MyJurnal
    Acquired subglottic cyst in infancy is almost always associated with episodes of early life intubation. Most cases typically presented late, usually days to months after extubation. We report a case of a subglottic cyst with different presentation than the norm. This case highlights that subglottic cyst can present acutely, and rapidly enlarging soon after the airway extubation. As the management of a large subglottic cyst can be challenging, a close observation for early diagnosis and intervention are recommended post extubation in the high-risk cases, such as in the premature infant.
  10. Abdul Aziz SA, Mohd Saparudin AK, Harun AZ
    Malays J Med Sci, 2013 May;20(3):23-30.
    PMID: 23966821 MyJurnal
    BACKGROUND: Different target-filter combinations in computed radiography have different impacts on the dose and image quality in digital radiography. This study aims to evaluate the mean glandular dose (MGD) and modulation transfer function (MTF) of various target-filter combinations by investigating the signal intensities of X-ray beams.

    METHODS: General Electric (GE) Senographe DMR Plus mammography unit was used for MGD and MTF evaluation. The measured MGD was compared with the dose reference level (DRL), whereas the MTF was evaluated using ImageJ 1.46o software. A modified Mammography Accreditation Phantom RMI 156 was exposed using different target-filter combinations of molybdenum-molybdenum (Mo-Mo), molybdenum-rhodium (Mo-Rh) and rhodium-rhodium (Rh-Rh) at two different tube voltages, 26 kV and 32 kV with 50 mAs.

    RESULTS: In the MGD evaluations, all target-filters gave an MGD value of < 1.5 mGy. The one-way ANOVA test showed a highly significant interaction between the MGD and the kilovoltage and target-filter material used (26 kV: F (2,12) = 49,234, P = 0.001;32 kV: F (2,12) = 89,972, P = 0.001). A Tukey post-hoc test revealed that the MGD for 26 kV and 32 kV was highly affected by the target-filter combinations. The test of homogeneity of variances indicates that the MGD varies significantly for 26 kV and 32 kV images (0.045 and 0.030 (P < 0.05), respectively). However, the one-way ANOVA for the MTF shows that no significant difference exists between the target-filter combinations used with 26 kV and 32 kV images either in parallel or perpendicular to the chest wall side F (2,189) = 0.26, P > 0.05).

    CONCLUSION: Higher tube voltage and atomic number target-filter yield higher MGD values. However, the MTF is independent of the X-ray energy and the type of target-filter combinations used.

  11. Aliyu AS, Mousseau TA, Ramli AT, Bununu YA
    Ambio, 2015 Dec;44(8):778-87.
    PMID: 26093469 DOI: 10.1007/s13280-015-0677-1
    The tin mining activities in the suburbs of Jos, Plateau State, Nigeria, have resulted in technical enhancement of the natural background radiation as well as higher activity concentrations of primordial radionuclides in the topsoil of mining sites and their environs. Several studies have considered the radiological human health risks of the mining activity; however, to our knowledge no documented study has investigated the radiological impacts on biota. Hence, an attempt is made to assess potential hazards using published data from the literature and the ERICA Tool. This paper considers the effects of mining and milling on terrestrial organisms like shrubs, large mammals, small burrowing mammals, birds (duck), arthropods (earth worm), grasses, and herbs. The dose rates and risk quotients to these organisms are computed using conservative values for activity concentrations of natural radionuclides reported in Bitsichi and Bukuru mining areas. The results suggest that grasses, herbs, lichens, bryophytes and shrubs receive total dose rates that are of potential concern. The effects of dose rates to specific indicator species of interest are highlighted and discussed. We conclude that further investigation and proper regulations should be set in place in order to reduce the risk posed by the tin mining activity on biota. This paper also presents a brief overview of the impact of mineral mining on biota based on documented literature for other countries.
  12. Juengsomjit R, Arayasantiparb R, Ghazali AB, Kosanwat T
    Heliyon, 2024 Oct 30;10(20):e39158.
    PMID: 39640765 DOI: 10.1016/j.heliyon.2024.e39158
    OBJECTIVE: and rationale: Odontogenic myxoma is an uncommon odontogenic tumor with locally aggressive behavior. The clinicopathological studies of odontogenic myxoma in Asian countries are very limited and only few studies have investigated the immunohistochemical profiles of the tumor. This study aims to investigate the clinicopathological and immunohistochemical features of odontogenic myxoma at the Faculty of Dentistry, Mahidol University over a 15-year period.

    METHODS: Archives of our institute were reviewed. Cases diagnosed as odontogenic myxoma were retrieved. Demographic, clinical, radiographic, and histopathological features of these cases were analyzed. In addition, immunohistochemical markers including vimentin, Ki-67, Bcl-2, and CD117 were performed. The correlation between immunohistochemical profiles and clinicopathological characteristics was evaluated.

    RESULTS: Sixteen cases of odontogenic myxoma were discovered. Fourteen cases were central type while two cases were peripheral type. The mean age of patients was 34.6 years with male-to-female ratio of 1:2.2. Mandible (68.8 %) was more affected than the maxilla (31.2 %). Bony expansion or jaw swelling (43.8 %) was the most common clinical feature. Most cases (71.4 %) presented with multilocular radiolucency. Histopathologically, tumors show stellate and spindle-shaped cells in a myxoid stroma with varying amounts of collagen fiber. All cases were positive for vimentin and Bcl-2. Half of the cases showed positive for Ki-67. Mast cells were presented in most cases (75.0 %). A significant correlation was found between the immunoexpression level of Bcl-2 and border of lesion in radiograph (p = 0.024).

    CONCLUSIONS: This study contributes to better understanding of the characteristics of odontogenic myxoma. Clinicians and pathologists should be aware of odontogenic myxoma, as its clinical and histopathological features may overlap with other tumors. The expression of Bcl-2 and presence of mast cell in this tumor may relate to its growth and aggressiveness. Despite its benign nature, odontogenic myxoma exhibits high recurrence, especially in lesion managed conservatively.

  13. Lee DE, Husain A, Khan A, Danish M, Jo WK
    Environ Res, 2025 Jan 01;264(Pt 1):120367.
    PMID: 39549909 DOI: 10.1016/j.envres.2024.120367
    Integrating photocatalysis with electrocatalysis may represent a synergistic approach to address environmental and energy challenges. In this context, we explored synthesizing a series of nanocomposite materials using a solid-state approach involving simple grinding and subsequent thermal treatment for the photocatalytic purification of dinoseb and electrocatalytic oxygen evolution (OER). Interestingly, among the series of synthesized materials, 40 wt percentage of 3D/2D/1D:ZnFe2O4/NiAl-LDH/MWCNTs ternary nanocomposite (40-NZM) showed highly improved dinoseb detoxification and OER efficiencies compared to those of pure materials. Importantly, approximately 98% detoxification of dinoseb was observed within 75 min of irradiation time under a visible light source. Remarkably, the 40-NZM nanocomposite exhibited the highest rate constant value (k = 4.1 × 10-2 min-1) with a favorable R2 (0.98) parameter. Furthermore, 40-NZM showed promising electrocatalytic OER performance, requiring only 217 mV of overpotential to achieve 10 mAcm-2 of current density with a smaller Tafel slope of 66.6 mVdec-1. Additionally, long-term stability was tested by recording 2000 cyclic voltammetry (CV) cycles. The results revealed that 40-NZM could maintain its catalytic activity for a longer duration as it required only 227 mV to attain 10 mAcm-2 even after 2000 CV cycles. Consequently, these outstanding characteristics of 40-NZM nanocomposite underscore the significant potential for catalytic water purification and sustainable energy conversion.
  14. Hisham SHA, Hadie SNH, Kasim F, Shamsuddin SA
    Korean J Med Educ, 2024 Dec;36(4):435-443.
    PMID: 39639637 DOI: 10.3946/kjme.2024.315
    The coronavirus disease 2019 pandemic has fundamentally reshaped anatomy education, offering invaluable insights to guide the future of anatomy pedagogy. As we transition into a post-pandemic era, it is crucial to integrate the lessons learned to create a more resilient, flexible, and effective educational environment. This paper examines the transformative strategies implemented at Universiti Sains Malaysia during the pandemic, focusing on the empowerment of blended learning, technology-enhanced tools, student-centered learning practical sessions, and enhancement of formative assessment. These strategies include integrating digital learning resources, such as the Virtual Anatomy Museum and online histology quizzes, with in-person instruction, fostering a supportive and interactive learning environment. Additionally, practical sessions were redesigned to emphasize collaborative learning, peer teaching, and developing critical thinking and communication skills. Formative assessments were integrated to provide continuous feedback and support ongoing learning. This comprehensive approach not only enhanced students' understanding of anatomical concepts but also improved their emotional well-being and overall learning experience. The lessons learned from the pandemic have paved the way for a more innovative and adaptive anatomy education that is well-prepared for future challenges.
  15. Alrawajfi A, Ismail MT, Al Wadi S, Atiewi S, Awajan A
    PeerJ Comput Sci, 2024;10:e2337.
    PMID: 39678293 DOI: 10.7717/peerj-cs.2337
    Data imputation strategies are necessary to address the prevalent difficulty of missing values in data observation and recording operations. This work utilizes diverse imputation methods to forecast and complete absent values inside a financial time-series dataset, specifically the daily prices of gold. The predictive accuracy of imputed data is assessed in comparison to the original entire dataset to ensure its robustness. The imputation methods are validated using actual closing price data obtained from a daily gold price website. The examined approaches include mean imputation, k-nearest neighbor (KNN), hot deck, random forest, support vector machine (SVM), and spline imputation. Their performance is evaluated based on several metrics, including mean error (ME), mean absolute error (MAE), root mean square error (RMSE), mean percentage error (MPE), and mean absolute percentage error (MAPE). The results indicate that the KNN approach consistently performs better than other methods in terms of all accuracy measures. Nevertheless, the precision of all techniques decreases as the proportion of missing data rises. Therefore, the KNN approach is suggested because to its exceptional performance and dependability in imputation tasks.
  16. Nurul-Laila S, Chai KS, Liza-Sharmini AT, Shatriah I
    Case Rep Ophthalmol Med, 2017;2017:1087821.
    PMID: 28546880 DOI: 10.1155/2017/1087821
    Kingella kingae had rarely been reported as a causative organism for corneal ulcer and had not been described before in vernal keratoconjunctivitis (VKC). Generally regarded as commensals of respiratory tract particularly in young children, it had however been isolated from the corneal ulcer scraping of both adult and children. We report a case of bacterial ulcer with isolation of Kingella kingae from the corneal scraping in a young child with underlying VKC.
  17. Choudhury DB, Gul K, Sehrawat R, Mir NA, Ali A
    Int J Biol Macromol, 2025 Jan 08;295:139578.
    PMID: 39793834 DOI: 10.1016/j.ijbiomac.2025.139578
    Bean proteins, known for their sustainability, versatility, and high nutritional value, represent a valuable yet underutilized resource, receiving less industrial attention compared to soy and pea proteins. This review examines the structural and molecular characteristics, functional properties, amino acid composition, nutritional value, antinutritional factors, and digestibility of bean proteins. Their applications in various food systems, including baked goods, juice and milk substitutes, meat alternatives, edible coatings, and 3D printing inks, are discussed. The physiological benefits of bean proteins, such as antidiabetic, cardioprotective, antioxidant, and neuroprotective effects, are also presented, highlighting their potential for promoting well-being. Our review emphasizes the diversity of bean proteins and highlights ultrasound as the most effective extraction method among available techniques. Beyond their physiological benefits, bean proteins significantly enhance the structural, technological, and nutritional properties of food systems. The functionality can be further improved through various modification techniques, thereby expanding their applicability in the food industry. While studies have explored the impact of bean protein structure on their nutritional and functional properties, further research is needed to investigate advanced modification techniques and the structure-function relationship. This will enhance the utilization of bean proteins in innovative and sustainable food applications.
  18. Almutairi R, Azuhairi AA, Mahmud A, Dablool AS
    Malays J Med Sci, 2023 Feb;30(1):185-197.
    PMID: 36875191 DOI: 10.21315/mjms2023.30.1.16
    BACKGROUND: Eating disorders (EDs) are characterised by an abnormal attitude towards food that causes someone to change their eating habits and behaviour. This study aimed to investigate the prevalence of EDs and their associated factors among female going-school adolescents in Jeddah, Saudi Arabia.

    METHODS: A cross-sectional study was conducted in five schools in Jeddah, Saudi Arabia, among a representative random sample of female adolescent students aged 13 years old-18 years old. A simple random sampling method was used to select the participants. An online self-administered questionnaire, the Arabic version of eating attitude test (EAT-26) and socio-cultural attitudes toward appearance questionnaire (SATAQ-4), was used.

    RESULTS: More than half (53.6%) of adolescent girls scored at or above the cut-off point of EAT-26. Around 45% of the participants had experienced family influence on their appearance and body shape, 36.7% had experienced peer influence on these factors, and 49.4% had experienced media influence. Family influence was significantly associated with EDs (P = 0.013).

    CONCLUSION: The high prevalence of EDs among female going-school adolescents in Jeddah, Saudi Arabia, is of great concern. To mitigate this problem, effective programmes must be designed to change their dietary habits while considering the effects of family, peer and media influence, as well as focusing on the importance of eating breakfast and practising physical activity.

  19. Yin J, Ibrahim S, Mohd NNA, Zhong C, Mao X
    Sci Rep, 2025 Jan 08;15(1):1267.
    PMID: 39779724 DOI: 10.1038/s41598-025-85168-y
    The growth in carbon emissions poses a severe challenge to global sustainable development, making it imperative to explore the impacts of economic restructuring and technological progress on Carbon Emission Performance (CEP). However, existing studies often lack an integrated analysis of economic restructuring and technological progress, while giving limited attention to the indirect role of Environmental Regulation (ER). This study constructs a multidimensional theoretical framework, breaking down economic restructuring into four dimensions-industrial structure, factor input, ownership, and new-type urbanization (NTU), and refining technological progress into technological innovation and energy efficiency. It uncovers the complex interplay among CEP, economic restructuring, technological progress, and ER. The findings reveal critical insights: (1) industrial structure suppresses CEP, whereas adjustments in factor input and ownership structure significantly enhance it; (2) the relationship between NTU and CEP exhibits a non-linear pattern; (3) compared to the technological innovation, energy efficiency provide a more substantial boost to CEP; and (4) ER positively moderates the impacts of factor input, ownership structure, and NTU. Finally, the study proposes recommendations for holistic economic restructuring and diversified ERs.
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