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Fulltext Effectiveness of structured teaching programme on transmission and prevention of human immunodeficiency virus/acquired immune deficiency syndrome among adolescent girls in Lowry Memorial High School, Bengaluru

Stephen N, Gusen NJ, Kumzhi PR, Gaknung B, Auta DA, Bulndi LB, et al.

Indian J Sex Transm Dis AIDS, 2018 03 26;41(1):73-82.
PMID: 33062987 DOI: 10.4103/ijstd.IJSTD_102_17

Background: Adolescence is a critical stage in human development. Most young people become sexually active during adolescence and are more likely to have multipartner and unprotected sex with high-risk behavior that predisposes them to sexually transmitted infections such as human immunodeficiency virus (HIV).
Objectives: The objective of the study was to evaluate the effectiveness of a structured teaching programme on transmission and prevention of HIV/acquired immune deficiency syndrome (HIV/AIDS) among adolescent girls.
Methods: An evaluative research approach was adopted, in which a preexperimental, one group pre- and post-test research design was used to evaluate the effectiveness of the structured teaching programme on transmission and prevention of HIV/AIDS among adolescent girls studying at Lowry Memorial High School, Bengaluru. A self-administered structured questionnaire was used for data collection. Data were presented in frequency tables and statistical graphs (bar charts) and analyzed using descriptive statistics (mean, standard deviation) and inferential statistical methods (Chi-square and paired "t"-tests) using SPSS version 21.
Results: The findings of the study revealed that the mean percentage difference in the pre- and post-test knowledge scores was statistically significant at 5% level (P < 0.05). The overall mean post-test knowledge score of adolescent girls on transmission and prevention of HIV/AIDS was 88.83%. It is apparently higher compared to the pretest knowledge score, which was 67.67% with enhancement of 21.16%. This implies that the structured teaching programme was effective in gaining knowledge of adolescent girls regarding transmission and prevention of HIV/AIDS.
Conclusion: Our study suggests that structured teaching programme enhanced the knowledge of the adolescent girls on transmission and prevention of HIV/AIDS. We, therefore, recommend that structured teaching programmes on transmission and prevention of HIV/AIDS should be encouraged among adolescents and youths to reduce the spread of HIV infection.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Fulltext Epidemiological and clinical features of Talaromycosis (Penicilliosis) Marneffei among human immunodeficiency virus-infected patients in Malaysia

Syaziah, I., Azura, S.S., Tzar, M.N.

Medicine & Health, 2018;13(2):103-113.
MyJurnal

The AIDS epidemic in Southeast Asia has led to a marked rise in the incidence of talaromycosis (penicilliosis) marneffei. The aim of this cross-sectional study was to determine the clinico-epidemiological features and outcome predictors of talaromycosis in Malaysia. We identified Talaromycosis marneffei cases from cultures of sterile specimens from 191 human immunodeficiency virus (HIV)- infected patients. Talaromycosis increased from 20-25 (2010-2011) to 45-50 cases per year (2012-2014). Talaromycosis was the HIV-presenting illness in 117 (61.3%) patients. The incidence of talaromycosis as HIV-presenting illness showed an increasing trend from 10.7 (2010) to 26.4 (2014) cases per 1000 new HIV patients. The patients were between 19 and 74 of age (mean 37.2+9.4 years) and the male to female ratio was 7.7:1. Malay (73, 38.2%) and Chinese (70, 36.3%) were the most prevalent ethnic groups. Common clinical manifestations included loss of weight (85.9%), fever (84.8%) and cough (67%), while skin lesions were only present in 42.9% cases. Common concurrent infections were oral candidiasis (79.6%), tuberculosis (36.1%) and hepatitis C infection (20.9%). Most patients (93.7%) were anaemic with mean haemoglobin level of 9.9+2.3 g/dL, 39% had impaired liver function, and 18.8% were neutropaenic. Median CD4 cell count was 16 cells/L. Most patients (70.4%) received intravenous amphotericin B followed by itraconazole. At 8-month follow up, 148 (81.8%) patients were alive while 33 (18.2%) had died. Intravenous drug abuse, concurrent toxoplasma encephalitis and concurrent Pneumocystis jiroveci pneumonia independently predicted death outcome in both univariate and multivariate logistic regression analyses.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Epidemiology of HIV and AIDS in the Asia-Pacific region

Dore GJ, Kaldor JM, Ungchusak K, Mertens TE

Med J Aust, 1996 Nov 4;165(9):494-8.
PMID: 8937371

The incidence of new HIV infections in Asia and the Pacific will soon pass that in Africa and is projected to increase into the next century. The AIDS epidemic arising from these infections will have enormous consequences for the health and socioeconomic development of a region encompassing more than half the world's population.

Matched MeSH terms: Acquired Immunodeficiency Syndrome/epidemiology*; Acquired Immunodeficiency Syndrome/transmission*
Fulltext Epilepsy stigma in Asia: the meaning and impact of stigma

Lim, Kheng-Seang, Tan, Chong-Tin

Neurology Asia, 2014;19(1):1-10.
MyJurnal

Stigma is conceptually broad and culturally variable. Understanding stigma from the conceptual theories, culturally application based on the word stigma in other languages, the definition of stigma and its synonyms, as well as the medical implications in other stigmatized disease such as AIDS, will help us to understand the complexity of stigma in epilepsy. This review investigated the meaning and types of stigma from different perspectives, leading to staging stigma into 5 levels, i.e. social identity, stereotype, prejudice, discrimination and social disability. In addition to the conventional categorization of stigma into social, felt, self-perceived or internalized stigma, new categories of stigma i.e. personal and general attitudes towards epilepsy based on a newly developed Public Attitudes Toward Epilepsy (PATE) scale was introduced. Courtesy stigma was further elaborated in related to Asian culture. Based on well-established and recently developed theories, the causation and impact of epilepsy stigma was discussed in an Asian context, especially from the aspects of language and society values which are culturally specific. Integrating these theories of causation, illness and stereotype perceptions were proposed to be the mediating mechanism of stigma, which led to the development of a practical and multi-dimensional stigmatization model, aiming to guide, widen and deepen the scope of future stigma research in epilepsy. Using the established model, together with review of related studies, research priorities in epilepsy stigma research especially in Asia focusing on five aspects, i.e. expanding population studies especially on significant others, understanding stigma from personal attitude perspective, investigating the cultural and social causation of stigma, and the impacts of stigma on patients as well as the family members, were proposed.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Fulltext Ethnic groups difference in discriminatory attitude towards HIV/AIDS patients among medical students: a cross-sectional study

Chew, B.H., Cheong, A.T.

Malaysian Journal of Medicine and Health Sciences, 2014;10(1):61-69.
MyJurnal

Medical students are future doctors who are trained to treat all kinds of diseases including people living with HIV/AIDS (PLWHA) without prejudice. Teaching basic scientific knowledge and technical skills is no longer adequate for today’s medical students. There is also a need for them to be provided with high personal and professional values. This study examined stigmatizing attitude towards people living with HIV/AIDS (PLWHA) among the medical students in a public medical school. The participants were stratified to preclinical-year (year 1 and year 2) and clinical-year (year 3 and year 4) medical students. Simple random sampling was carried out to select 170 participants from each category of students. Self-administered questionnaires captured socio-demographic data, HIV/AIDS knowledge and stigmatisation attitudes towards PLWHA. Multiple linear regression was used to assess the relationship between ethnic groups and stigmatization attitude. Three hundred and forty participants were recruited. Malay medical students who did not have previous encounter with PLWHA were associated with stigmatizing attitude towards HIV/AIDS patients, whereas clinical-year medical students who had no clinical encounter with PLWHA were more likely to feel uncomfortable with PLWHA. Malay ethnicity and medical students in clinical years who had not encounter a PLWHA were more likely to have stigmatizing attitude towards PLWHA.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Facilitators and Barriers Affecting Adherence Among People Living With HIV/AIDS: A Qualitative Perspective

Ahmed SI, Farooqui M, Syed Sulaiman SA, Hassali MA, Lee CKC

J Patient Exp, 2019 Mar;6(1):33-40.
PMID: 31236449 DOI: 10.1177/2374373518770805

Background: It is widely accepted that for HIV-positive persons on highly active antiretroviral treatment, high levels of adherence to treatment regimens are essential for promoting viral suppression and preventing drug resistance.
Objectives: This qualitative study examines factors affecting the adherence to HIV/AIDS treatment among patients with HIV/AIDS at a local hospital in Malaysia.
Methods: The data from purposefully selected patients were collected by in-depth interviews using a pretested interview guide. Saturation was reached at the 13th interview. All interviews were audio-taped and transcribed verbatim for analysis using thematic content analysis.
Results: Fear and stigma of perceived negative image of HIV diagnosis, lack of disease understating, poor support from the community, and perceived severity or the treatment side effects were among the reasons of nonadherence. Appropriate education and motivation from the doctors and reduction in pill burden were suggested to improve adherence.
Conclusion: Educational interventions, self-management, and peer and community supports were among the factors suggested to improve adherence. This necessitates uncovering efficient ways to boost doctor-patient communication and recognizing the role of support group for the social and psychological well-being of the patients.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Factors Affecting Voluntary HIV Testing Among General Adult Population: A Cross-Sectional Study in Sarawak, Malaysia

Lemin AS, Rahman MM, Pangarah CA, Kiyu A

J Family Reprod Health, 2020 Mar;14(1):45-51.
PMID: 32863838

Objective: Voluntary HIV testing is one of the key strategies in the HIV/AIDS prevention and control program. New National Strategic Plan for 2016-2030 in Malaysia, adapt three zeros viz. 'zero new infections of HIV/AIDS, zero discrimination and zero AIDS-related deaths'. This study aimed to determine the predictors of voluntary HIV testing in Sarawak. Materials and methods: A cross-sectional study was conducted with a total of 900 respondents (450 males and 450 females) from the state of Sarawak, aged 18 years and above, who were selected by gender-stratified multistage cluster sampling. Data were obtained by face-to-face interview using a pretested questionnaire. Binary logistic regression analysis was done to determine the potential predictors for voluntary HIV testing. Results: The prevalence of HIV testing was higher among female respondents (26%) compared to male respondents (14.2%), and the difference was statistically significant (p < 0.001). Binary logistic regression analysis revealed that household income more than MYR 1501 (p = 0.009), not living with a partner (p < 0.001) and discussion on HIV/AIDS (p = 0.019) appeared to be predictors for the male respondents, while, ethnicity was statistically significant for female respondents (p < 0.001). Conclusion: The utilisation of HIV testing was low in both males and females. Thus, the finding of this study could be considered when designing HIV education and screening program in Sarawak.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Factors associated with poor CD4 and viral load outcomes in patients with HIV/AIDS

Syed IA, Sulaiman SA, Hassali MA, Syed SH, Shan LH, Lee CK

J Med Virol, 2016 May;88(5):790-7.
PMID: 26399724 DOI: 10.1002/jmv.24389

Suboptimal viral suppression and CD4 response to antiretroviral treatment (HAART) is known to cause poor outcomes with the increase cost of treatment. We aimed to assess factors associated with such control among HIV/AIDS patients in Malaysia. Four hundred and six HIV/AIDS patients, using Antiretroviral Therapy (ART) for at least the past three months, treated as outpatients at medication therapy adherence clinics (MTAC) were recruited. CD4 cell counts, viral load readings along with co-variants such as socio-demographic factors, adverse drug reactions, comorbidities, and medication record were obtained. Statistical Package for Social Sciences (SPSS(®) ) version 18 and STATA IC(®) version 12 were used for data analysis. CD4 counts were found highest among those within the age category 41-50 years (390.43 ± 272.28), female (402.64 ± 276.14), other ethnicities (400.20 ± 278.04), and participants with no formal education (414.87 ± 290.90). Patients experiencing adverse effects had a 2.28 (95%CI:1.25-4.18) fold greater risk of poor CD4 control, while patients with comorbidities had 2.46 (95%CI:1.02-5.91) fold greater risk of mild viral suppression. Adverse drug reactions, co-morbidities were found to be significantly associated with poor immunological and virological outcomes in HIV/AIDS patients. However, a comprehensive evaluation is needed to better understand other confounders.
Study site: Medication therapy adherence clinic, Hospital Sungai Buloh, Selangor, Malaysia

Matched MeSH terms: Acquired Immunodeficiency Syndrome*
Fulltext Faktor perbezaan tahap pengetahuan HIV/AIDS dan stigma pelajar GMI dan UKM mengikut tahap pendidikan

Muhammad Ajib bin Abd R, Nasrudin S

Jurnal Psikologi Malaysia, 2016;30:61-68.

HIV /AIDS is a global epidemic problem that is faced by many countries. There is a drastic increase of infection cases in children, youths, adults and elderly. Among students, there is a low level of knowledge that affects the comprehension elasticity based on the educational level which contributes to the increasing stigma among students. The focus of this study is to examine the differences of HIV/AIDS knowledge levels and students' stigma according to their levels of education. This study used HIV Knowledge Questionnaires (HIV-K-Q) version of 45 items and The Berger HIV Stigma Scale version of 40 items. 130 students from UKM and GMI participated in the study. Results showed that there were significant differences in the knowledge levels and stigma of HIV/AIDS between students' educational levels (Diploma level, Bachelor and Masters). The findings can assist educational institutions to develop the awareness of HIV/AIDS knowledge by targeting all levels of students' education. The implementation of various campaigns, talks, and interventions of reducing the stigma should be refined and planned as an annual program.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Fulltext Fuzzy Lambda-Max criteria weight determination for feature selection in clustering

Nurul Adzlyana Mohd Saadon, Rosma Mohd Dom, Nurazzah Abd Rahman

Pertanika Journal of Science & Technology, 2017;25(103):241-254.
MyJurnal

Clustering refers to reducing selected features involved in determining the clusters. Raw data might come with a lot of features, including unimportant ones. A hybrid similarity measure (discovered in 2014) used in selecting features can be improvised as it might select all the attributes, including insignificant ones. This paper suggests Fuzzy Lambda-Max to be used as a feature selection method since Lambda-Max is normally used in ranking of alternatives. A set of AIDS data is used to measure the performance. Results show that Fuzzy Lambda-Max has the ability to determine criteria weights and ranking the criteria. Hence, feature selection can be done by choosing only the important criteria.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Fulltext Global health film club - bringing global health issues and activism to local communities

Nicholas Pang, Jiann Lin Loo

Malaysian Journal of Medicine and Health Sciences, 2019;15(106):50-50.
MyJurnal

Introduction: Global health awareness is sorely lacking in medical curricula and the general public, leading to increasing apathy and decreased levels of volunteerism. Much knowledge about pertinent global health issues is sequestered with academicians and researchers, with little public trickle down. The aim of the study was to increase awareness among Sabahan public about global health issues and promote discussion. Methods: A global health film club was established at community level and discussions about issues and potential individual action points was conducted. Films were screened every month in both UMS and Palliative Care Center Sabah. Global health issues ranging from First World manipulation of HIV/AIDS medication prices, deregulation of medical devices industries, heroin addiction, ADHD drug abuse, and stigma in psychiatry were covered. Public participants’ responses were collected qualitatively. Results: The films largely were well received by participants, with most participants prefer-ring the expose-type films over the more narrative approaches. Films spurred discussion about how foreign or global issues were related to local level, for example unscrupulous sale of medical devices in Malaysian populations and abuse of sleeping medications from local health providers. Also each film screening vastly increased participants’ awareness of pertinent issues, and spurred them to evangelise about said issues to others and take small actions. Conclusion: Global health is a somewhat neglected part of medical and community curricula. Lack of awareness about global health issues reduces the public’s capacity for collective action in exerting pressure on stakeholders, governments, and civil society in taking action. It is hoped such regular global health film screenings at local level brings literacy on urgent public health issues to the people for whom it matters most – the communities where ad-verse global health consequences eventually arise.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Global update: Malaysia

AIDSlink, 1993 Jun-Aug;?(23):15.
PMID: 12159245
Matched MeSH terms: Acquired Immunodeficiency Syndrome*
HIV / AIDS is a challenge we have to face -- Colin Hollis

Asian Forum Newsl, 2000 May-Jul.
PMID: 12296248

PIP: On July 21, 2000, the Asian Forum of Parliamentarians on Population and Development (AFPPD) Malaysia, in cooperation with the UN Population Fund and the UN Development Program (Malaysia), organized the National HIV/AIDS Seminar for Parliamentarians in Kuala Lumpur, Malaysia. During the seminar, Mr. Colin Hollis, secretary general of AFPPD, spoke about the challenge posed by HIV/AIDS on the government. He noted that the epidemic is a part of life and these figures should not only challenge the assumptions of legislators but for them to act as well. He further informed that AFPPD would organize the Asia-Africa Meeting of Parliamentarians and Asia European Dialogue.

Matched MeSH terms: Acquired Immunodeficiency Syndrome*
HIV Treatment Adherence - A Shared Burden for Patients, Health-Care Providers, and Other Stakeholders

Abdulrahman SA, Ganasegeran K, Rampal L, Martins OF

AIDS Rev, 2019;21(1):28-39.
PMID: 30899114 DOI: 10.24875/AIDSRev.19000037

Successful HIV treatment is contingent on sustained high levels of treatment adherence. Several barriers to optimal adherence have been documented. In this article, we first review the global burden of non-adherence among HIV/AIDS positive individuals on a public health scale. Second, we synthesized available evidence from different study designs and stratified across the European, African, and Asian literature to determine the factors influencing adherence to scheduled clinic appointments and medication non-adherence. Third, we discuss common measurement techniques that quantify the magnitude of non-adherence, their relative advantages and limitations in current practice. From January to May 2018, we reviewed guidelines, standard operating procedures, journal articles, and book chapters on treatment adherence among HIV patients receiving adherence to antiretroviral therapy (ART) globally. We searched PubMed, Medline, Google Scholar, and Cochrane Database of Systematic Reviews with the search terms "adherence," "adherence behavior," "medication adherence," and "HIV patients," or "HIV/AIDS," and "Antiretroviral Therapy" or "ART" or "ARVs" or "highly active ART " from 2000 to 2017. We also identified articles through searches of authors' files and previous research on HIV. We included only papers published in English in this review. We then generated a final list of reference on the basis of originality and the broad scope of this review. We found rich literature evidence of research findings and best practice recommendations on the importance of adherence in HIV/AIDS management, a general understanding of factors associated with non-adherence and approaches to investigating non-adherence behavior among different populations. We observed significant contextual differences exist with regard to barriers and burden of non-adherence among these populations.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
HIV in Southeast Asia

Abrams S

Harv AIDS Rev, 1998.
PMID: 12294443
Matched MeSH terms: Acquired Immunodeficiency Syndrome*
Fulltext HIV in south and South-East Asia

Yasmin AM

Med J Malaysia, 1997 Dec;52(4):311-2.
PMID: 10968105
Matched MeSH terms: Acquired Immunodeficiency Syndrome/epidemiology
HIV infection and the clinical manifestations of AIDS

Goh TK

Family Practitioner, 1986;9(2):27-32.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Fulltext HIV- and AIDS-related Ocular Manifestations in Tanzanian Patients

Sahoo S

Malays J Med Sci, 2010 Jan;17(1):12-6.
PMID: 22135520 MyJurnal

Although around 70% of HIV+ cases used to have ocular manifestations, the late reporting of cases often results in severe forms of ocular morbidity that would otherwise have been prevented. The objective of this study was to describe the ocular manifestations of HIV and AIDS-related patients who had been admitted to TM Jafferji Hospital, Dar-es-Salaam, Tanzania.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Fulltext HIV-related stigma and discriminatory attitudes among a semi-urban population

Lugova H, Mon AA, Daher AM, Suleiman A

Malays J Med Sci, 2015 Sep;22(5):64-69.
PMID: 28239270

BACKGROUND: Stigma and discriminatory attitudes (SDAs) have a negative impact on human immunodeficiency virus (HIV) prevention, testing, and treatment as well as on family and social networks. There is a lack of understanding about HIV-related SDAs among people living outside large cities. This study is aimed to determine the level of HIV-related SDAs among a semi-urban population in Malaysia and to compare the SDA results among people with different sociodemographic characteristics.

METHODS: A sample of 106 respondents was generated by convenience sampling during the screening campaign in Alor Gajah, Malaysia. Data collection was carried out based on a pre-tested questionnaire via face-to-face interviews.

RESULTS: More than half of the respondents (62.3%) thought that an HIV-positive teacher should not be allowed to continue teaching at school; 81.1% were unsure or were unwilling to care for their family member with AIDS at home; 81.2% thought children with HIV/AIDS should not continue to be raised in families; and 77.3% thought they would not reveal if a family member had HIV/AIDS.

CONCLUSION: Priority should be given to evidence-based interventions to reduce HIV-related SDAs. This study did not reveal any significant relationship between sociodemographic profiles and HIV-related SDAs. Therefore, further research with a larger sample size is needed to investigate the underlying causes of HIV-related SDAs.

Matched MeSH terms: Acquired Immunodeficiency Syndrome
Fulltext HIV/AIDS Related Stigma and Discrimination against PLWHA in Nigerian Population

Dahlui M, Azahar N, Bulgiba A, Zaki R, Oche OM, Adekunjo FO, et al.

PLoS One, 2015;10(12):e0143749.
PMID: 26658767 DOI: 10.1371/journal.pone.0143749

HIV/AIDS remain a major public health concern in Nigeria. People living with HIV/AIDS (PLWHA) face not only personal medical problems but also social problems associated with the disease such as stigma and discriminatory attitudes. This study provides an insight into HIV/AIDS related stigma and discrimination against PLWHA in Nigeria.

Matched MeSH terms: Acquired Immunodeficiency Syndrome

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