MyMedR

Fulltext Prevalence of eye diseases and visual impairment among the rural population - a case study of Temerloh Hospital

Thevi T, Maslina B, Reddy SC

Malays Fam Physician, 2012;7(1):6-10.

PMID: 25606238

Objective: To determine the prevalence of eye diseases and visual impairment among new patients at the eye clinic of Hospital Sultan Haji Ahmad Shah, Temerloh, Pahang.
Method: In this cross-sectional prospective study, 1081 new patients were examined over a period of six months. Age, gender, ethnicity, visual acuity and diagnosis were noted from the medical records.
Results: Out of 1081 examined, 607 (56.1%) were males, 783 (72.4%) were Malays. The mean age of patients was 45.2 years (ranging from one month to 91 years). Cataract (248, 22.9%) was the most common eye disease, followed by retinal diseases (124, 11.5%) and ocular trauma (106, 9.8%). Majority of the patients (48) suffering from ocular trauma had foreign body cornea. In 85 premature infants screened for retinopathy, 19 showed different stages of retinopathy of prematurity. Visual impairment was noted in 89 (8.2%) patients, severe visual impairment in 12 (1.1%) and blindness in 35 (3.2%); vision could not be determined in 85 premature infants (7.9%). Cataract was singled out as the cause of severe visual impairment in 11 out of 12 patients.
Conclusion: Health education at primary health centres and availability of eye specialists in all the district hospitals will facilitate the rehabilitation of visually impaired and blind persons by providing early treatment for eye problems (specifically prescription for spectacles, medical treatment and cataract surgery with intraocular lens implantation).
Keywords: Visual impairment, cataract, diabetic retinopathy, glaucoma, refractive errors, ocular trauma, conjunctivitis
Study site: Eye clinic, Hospital Sultan Haji Ahmad Shah, Temerloh, Pahang, Malaysia

Matched MeSH terms: Eye Diseases

Fulltext The fourth report of the National Eye Database 2010

Citation: The fourth report of the National Eye Database 2010. Goh PP, Salowi MA, editors. Kuala Lumpur: Clinical Research Centre; 2012

Matched MeSH terms: Eye Diseases

Fulltext Familial exudative vitreoretinopathy presenting with unilateral rhegmatogenous retinal detachment in a Malay teenager

Leow SN, Bastion ML

BMJ Case Rep, 2013;2013.

PMID: 23645703 DOI: 10.1136/bcr-2013-009664

To describe a case of familial exudative vitreoretinopathy presenting with unilateral rhegmatogenous retinal detachment in a Malay teenager.

Matched MeSH terms: Eye Diseases, Hereditary/diagnosis*; Eye Diseases, Hereditary/surgery

Fulltext The fifth report of the National Eye Database 2011

Citation: The fifth report of the National Eye Database 2011. Goh PP, Salowi MA, editors. Kuala Lumpur: Clinical Research Centre; 2013

Matched MeSH terms: Eye Diseases

Fulltext The sixth report of the National Eye Database 2012

Citation: The sixth report of the National Eye Database 2012. Goh PP, Salowi MA, editors. Kuala Lumpur: Clinical Research Centre; 2013

Matched MeSH terms: Eye Diseases

Dental care access among individuals with Down syndrome: a Malaysian scenario

Abdul Rahim FS, Mohamed AM, Marizan Nor M, Saub R

Acta Odontol Scand, 2014 Nov;72(8):999-1004.

PMID: 25029211 DOI: 10.3109/00016357.2014.936036

The purpose of this cross-sectional study was to assess the legal representatives' perceptions on dental care access of individuals with Down syndrome (DS) compared to their non-DS siblings in Peninsular Malaysia.

Matched MeSH terms: Eye Diseases/therapy

Fulltext Full thickness macular hole: Early intervention is an important factor in visual prognosis

Ng HK, Yaakub A, Ong LB

Malays Fam Physician, 2014;9(3):42-8.

PMID: 26425305 MyJurnal

Full thickness macular hole is an eye disease, which can cause permanent visual impairment. Current advancement in vitreoretinal surgery has high success rates in repairing them, leading to a significant visual improvement, especially if patient presents early. In this article, three cases of idiopathic full thickness macular hole with different visual outcomes have been presented. All cases were referred by the primary care practitioners and had undergone macular hole surgery with the same vitreoretinal surgeon. The visual outcome was best in the patient who had the earliest presentation and referral. Early detection and referral of these patients is vital so that early surgical intervention can be carried out to improve their vision.

Matched MeSH terms: Eye Diseases

A comparative analysis of avoidable causes of childhood blindness in Malaysia with low income, middle income and high income countries

Koay CL, Patel DK, Tajunisah I, Subrayan V, Lansingh VC

Int Ophthalmol, 2015 Apr;35(2):201-7.

PMID: 24652461 DOI: 10.1007/s10792-014-9932-x

To determine the avoidable causes of childhood blindness in Malaysia and to compare this to other middle income countries, low income countries and high income countries. Data were obtained from a school of the blind study by Patel et al. and analysed for avoidable causes of childhood blindness. Six other studies with previously published data on childhood blindness in Bangladesh, Ethiopia, Nigeria, Indonesia, China and the United Kingdom were reviewed for avoidable causes. Comparisons of data and limitations of the studies are described. Prevalence of avoidable causes of childhood blindness in Malaysia is 50.5 % of all the cases of childhood blindness, whilst in the poor income countries such as Bangladesh, Ethiopia, Nigeria and Indonesia, the prevalence was in excess of 60 %. China had a low prevalence, but this is largely due to the fact that most schools were urban, and thus did not represent the situation of the country. High income countries had the lowest prevalence of avoidable childhood blindness. In middle income countries, such as Malaysia, cataract and retinopathy of prematurity are the main causes of avoidable childhood blindness. Low income countries continue to struggle with infections such as measles and nutritional deficiencies, such as vitamin A, both of which are the main contributors to childhood blindness. In high income countries, such as the United Kingdom, these problems are almost non-existent.

Matched MeSH terms: Eye Diseases/complications; Eye Diseases/epidemiology*

Phospholipase A2 group v in benign familial fleck retina in a set of triplets

Bin NJ, Heng HM, Poh R, Noor SM, Subrayan V

Retina, 2015 Jun;35(6):1266-72.

PMID: 25549071 DOI: 10.1097/IAE.0000000000000446

To evaluate the association of phospholipase A2, Group V (PLA2G5), with benign familial fleck retina in a consanguineous family with triplets.

Matched MeSH terms: Eye Diseases, Hereditary/diagnosis; Eye Diseases, Hereditary/genetics*

Fulltext Orbital compartment syndrome in idiopathic orbital inflammatory disease: A case report

Tiong KI, Aziz S, Hazlita I

Med J Malaysia, 2015 Oct;70(5):316-7.

PMID: 26556124 MyJurnal

Orbital compartment syndrome (OCS) is a visual threatening ocular emergency. We report a 50-year-old male with acute presentation of OCS, a rare manifestation of idiopathic orbital inflammatory disease. At presentation, high intraocular pressure was reduced by prompt lateral canthotomy and cantholysis. The disease responded to systemic steroids and treatment resulted in good visual outcome. Detail evaluation and early detection and treatment are mandatory to prevent permanent vision loss.
Keywords: Sarawak General Hospital

Matched MeSH terms: Eye Diseases

Fulltext The seventh report of the National Eye Database 2013

Citation: The seventh report of the National Eye Database 2013. Salowi MA, et al, editors. Kuala Lumpur: Clinical Research Centre; 2015

Matched MeSH terms: Eye Diseases

Fulltext Optic neuropathy in thyroid eye disease: A case series

Salleh NA, Wong HS, Mohd Isa HD

Korean J Fam Med, 2016 May;37(3):197-201.

PMID: 27274392 DOI: 10.4082/kjfm.2016.37.3.197

In patients with thyroid disease, ocular involvement or thyroid ophthalmopathy is common, irrespective of their thyroid status. A common feature of thyroid eye disease is eyelid retraction, which leads to a classical starry gaze (Kocher sign). Treatment with radioactive iodine (RAI) is a known therapy for hyperthyroidism. However, this treatment may lead to or worsen thyroid ophthalmopathy. We report a case series of two patients with thyrotoxicosis, who presented with an atypical and subtle occurrence of thyroid eye disease (TED) soon after RAI therapy. One of the patients was initially diagnosed and treated for dry eyes; however, over a period of time, the patient's vision progressively deteriorated. Clinical and radiological investigations confirmed thyroid ophthalmopathy with low serum thyroid hormone levels. Both patients recovered well after immediate intensive intravenous steroid treatment. These cases highlight the importance of recognizing partial ptosis as one of the presenting signs of active TED among general practitioners and physicians.

Matched MeSH terms: Eye Diseases

Fulltext Unicentric Castleman Disease: An Unusual Cause of An Isolated Neck Mass

Kumar A, Aggarwal K, Agrawal H, Sharma S, Garg PK

Malays J Med Sci, 2016 Jul;23(4):86-9.

PMID: 27660550 DOI: 10.21315/mjms2016.23.4.12

Castleman disease (CD) is a rare lymphoproliferative disorder of unknown aetiology. It manifests in two distinct clinical presentations: unicentric and multicentric. Unicentric CD is rare and may present as an isolated neck mass. A 22-year-old man presented with a 6-month history of right neck swelling that occupied the posterior triangle of the right neck region. After surgical exploration, a solitary, well defined, and hyper vascular mass was excise. A histopathological examination confirmed the lesion as CD, hyaline-vascular variant. CD of the neck is a diagnosis that is usually not taken into consideration while evaluating neck masses due to its rarity and unassuming presentation. It should be keep in the differential diagnosis of neck masses as the clinical and radiological features evade a firm diagnosis. The treatment of unicentric CD is complete surgical excision, which cures the patient.

Matched MeSH terms: Eye Diseases, Hereditary

Fulltext Delayed onset porous polyethylene implant-related inflammation after orbital blowout fracture repair: four case reports

Aryasit O, Ng DS, Goh ASC, Woo KI, Kim YD

BMC Ophthalmol, 2016 Jul 07;16:94.

PMID: 27387333 DOI: 10.1186/s12886-016-0287-0

BACKGROUND: Porous polyethylene implants are commonly used in orbital blowout fracture repair because of purported biocompatibility, durability, and low frequency of complications. Delayed inflammation related to porous polyethylene sheet implants is very rare and no case series of this condition have been reported.

CASE PRESENTATION: This is a retrospective review of clinical presentations, radiographic findings, histopathological findings, treatments, and outcomes of patients who developed delayed complications in orbital blowout fracture repair using porous polyethylene sheets. Four male patients were included with a mean age of 49 years (range 35-69 years). Blowout fracture repair was complicated with implant-related inflammation 10 months, 2 years, 3 years, and 8 years after surgery. Chronic and subacute orbital inflammatory signs were noted in two patients and acute fulminant orbital inflammation was found in two patients. Three patients developed peri-implant abscesses and one patient had a soft tissue mass around the implant. All patients underwent implant removal and two of these patients with paranasal sinusitis had sinus surgery. Histopathological findings revealed chronic inflammatory changes with fibrosis, and one patient had foreign body granuloma with culture positive Staphylococcus aureus.

CONCLUSIONS: Delayed complications with porous polyethylene sheets used in orbital blowout fracture repair may occur many years following the initial surgery in immunocompetent patients. Low-grade or fulminant inflammation could complicate blowout fracture repair related with the implant.

Matched MeSH terms: Eye Diseases/etiology*

Revisiting the role of erythropoietin for treatment of ocular disorders

Shirley Ding SL, Leow SN, Munisvaradass R, Koh EH, Bastion ML, Then KY, et al.

Eye (Lond), 2016 Oct;30(10):1293-1309.

PMID: 27285322 DOI: 10.1038/eye.2016.94

Erythropoietin (EPO) is a glycoprotein hormone conventionally thought to be responsible only in producing red blood cells in our body. However, with the discovery of the presence of EPO and EPO receptors in the retinal layers, the EPO seems to have physiological roles in the eye. In this review, we revisit the role of EPO in the eye. We look into the biological role of EPO in the development of the eye and the physiologic roles that it has. Apart from that, we seek to understand the mechanisms and pathways of EPO that contributes to the therapeutic and pathological conditions of the various ocular disorders such as diabetic retinopathy, retinopathy of prematurity, glaucoma, age-related macular degeneration, optic neuritis, and retinal detachment. With these understandings, we discuss the clinical applications of EPO for treatment of ocular disorders, modes of administration, EPO formulations, current clinical trials, and its future directions.

Matched MeSH terms: Eye Diseases/drug therapy*; Eye Diseases/etiology; Eye Diseases/physiopathology; Eye Diseases/prevention & control

Fulltext The eighth report of the National Eye Database 2014

Citation: The eighth report of the National Eye Database 2014. Goh PP, Salowi MA, Adnan TH, Sa'at N, editors. Kuala Lumpur: Clinical Research Centre; 2016

Matched MeSH terms: Eye Diseases

Ocular symptoms and tear film break up time (BUT) among junior high school students in Penang, Malaysia - Associations with fungal DNA in school dust

Norbäck D, Hashim JH, Hashim Z, Sooria V, Ismail SA, Wieslander G

Int J Hyg Environ Health, 2017 06;220(4):697-703.

PMID: 28254266 DOI: 10.1016/j.ijheh.2017.01.016

BACKGROUND: There are few studies on ocular effects of indoor mould exposure in schools, especially in the tropics OBJECTIVE: To study associations between eye symptoms and tear film break up time (BUT) in students and demographic data and fungal DNA in schools.

METHODS: A school environment study was performed among randomly selected students in eight randomly selected secondary schools in Penang, Malaysia. Information on eye symptoms and demographic data was collected by a standardised questionnaire. BUT was measured by two methods, self-reported BUT (SBUT) and by the non-invasive Tearscope (NIBUT). Dust was collected by vacuuming in 32 classrooms and analysed for five fungal DNA sequences. Geometric mean (GM) for total fungal DNA was 7.31*104 target copies per gram dust and for Aspergillus/Penicillium DNA 3.34*104 target copies per gram dust. Linear mixed models and 3-level multiple logistic regression were applied adjusting for demographic factors.

RESULTS: A total of 368 students (58%) participated and 17.4% reported weekly eye symptoms the last 3 months. The median SBUT and TBUT were 15 and 12s, respectively. Students wearing glasses (OR 2.41, p=0.01) and with a history of atopy (OR=2.67; p=0.008) had more eye symptoms. Girls had less eye symptoms than boys (OR=0.34; p=0.006) Indoor carbon dioxide in the classrooms was low (range 380-720ppm), temperature was 25-30°C and relative air humidity 70-88%. Total fungal DNA in vacuumed dust was associated with shorter SBUT (4s shorter per 105 target copies per gram dust; p=0.04) and NIBUT (4s shorter per 105 target copies per gram dust; p<0.001). Aspergillus/Penicillium DNA was associated with shorter NIBUT (5s shorter per 105 target copies per gram dust; p=0.01).

CONCLUSION: Fungal contamination in schools in a tropical country can be a risk factor for impaired tear film stability among students.

Matched MeSH terms: Eye Diseases/diagnosis; Eye Diseases/etiology*; Eye Diseases/epidemiology

Fulltext Community eye service program: factors associated with delayed presentation to a tertiary centre post community screening

Nor Hafiza I., Lathalakshmi, T., Ab Hamid Siti-Azrin, Liza-Sharmini A.T.

Journal of Biomedical and Clinical Sciences, 2017;2(2):42-47.

MyJurnal

Early detection and prompt treatment of eye diseases can prevent visual disability. To our knowledge, there is no published data on factors associated with delayed presentation of eye diseases in Malaysia. Our objective is to determine the proportion of patients with eye disease who had a delayed presentation to an ophthalmologist after an initial screening, as well as the factors associated with delay in seeking treatment. This was a retrospective cohort study of patients with eye diseases detected during a Community Eye Survey (CES) program from September 2004 to December 2012 who were referred to the ophthalmologist in Hospital Universiti Sains Malaysia (USM). Delayed presentation of eye disease was defined as patients who came to the eye clinic more than six months after eye screening. Multiple logistic regression was used for analyses. A total of 434 patients who were referred to Hospital USM, Kubang Kerian were included in the study. Their mean (standard deviation) age was 55.65 (21.62) years. The majority of patients (76%) had delayed presentation of eye disease post screening. Type of ocular diseases was not associated with delayed presentation. The factors associated with delayed presentation were unemployment (adjusted odds ratio (OR): 2.51, 95% CI (1.36, 4.64), p

Study site: Hospital Universiti Sains Malaysia (HUSM)

Matched MeSH terms: Eye Diseases

Fulltext The ninth report of the National Eye Database 2015

Citation: The ninth report of the National Eye Database 2015. Goh PP, Salowi MA, Adnan TH, Sa'at N, editors. Kuala Lumpur: Clinical Research Centre; 2017

Matched MeSH terms: Eye Diseases

Fulltext Varicella zoster causing preseptal cellulitis - uncommon but possible

Qualickuz Zanan NH, Zahedi FD, Husain S

Malays Fam Physician, 2017;12(3):37-39.

PMID: 29527280

Background: Varicella has been known to be a harmless childhood disease. However, it has been reported that severe complications have taken place following Varicella infection, in both immunocompetent, as well as immunocompromised, individuals. Cutaneous complications of Varicella may manifest as preseptal cellulitis, albeit rarely.

Report: We present a case of a 4-year-old boy who presented with symptoms and signs of preseptal cellulitis following Varicella infection. He was referred to the otorhinolaryngology team for a nasoendoscopy to rule out sinusitis, in view of the fear that a child presenting with a swollen red eye may be a case of true orbital cellulitis. He was treated successfully with intravenous antibiotics and surgical drainage of the preseptal collection.

Conclusion: It is imperative for clinicians to be aware that a simple Varicella infection may lead to cutaneous complications in the pediatric age group, especially in children who are 4 years and younger. They may develop preseptal cellulitis, whose presentation might mimic that of orbital cellulitis. Empirical treatment with antibiotics would be advantageous for the patient. A nasoendoscopic examination may also be warranted in these cases to rule out sinusitis as a cause of orbital cellulitis.

Matched MeSH terms: Eye Diseases

Displaying publications 61 - 80 of 87 in total