MyMedR

Fulltext A rare cause of respiratory distress in neonates – congenital nasal pyriform aperture stenosis

Yeong, Lee-chian, Veno Rajendran, Che Zubaidah Che Daud, Hung, Liang-choo

Malaysian Journal of Paediatrics and Child Health, 2016;22(101):0-0.

MyJurnal

Neonates are obligate nasal breather until they are at least two to five months old. Congenital nasal airway obstruction is one of the commonest causes of respiratory problem in newborn. Congenital nasal pyriform aperture stenosis (CNPAS) was first described by Brown et al in 1989 [1] and is a rare cause of nasal airway obstruction which may clinically mimic choanal atresia.(Copied from article)

Matched MeSH terms: Infant, Newborn

A report on superstition and belief of the Malays, Indians and Chinese in Kuala Lumpur in regard to pregnancy, childbirth and the newborn babe

WYLDE EM

Med J Malaya, 1959 Jun;13:322-6.

PMID: 13846271

Matched MeSH terms: Infant, Newborn

A retrospective analysis of oral and maxillofacial biopsied specimens in Malaysian newborns and infants

Binti Shuhairi NN, Bt Abdul Jalil A, Lau SH, Bt Mohd Ghazali S, Kee CC

Int J Paediatr Dent, 2021 Jul;31(4):496-503.

PMID: 32815206 DOI: 10.1111/ipd.12719

BACKGROUND: Globally, research on oral and maxillofacial lesions among newborns and infants remains limited.

AIM: To describe demographic patterns, histopathological findings, and locations of oral and maxillofacial lesions in newborns (birth-1 month) and infants (>1 month-2 years) reported over 51 years.

DESIGN: A retrospective cross-sectional study on histopathological records of newborns and infants was conducted. Patients' demographic characteristics (age, gender, and race), histopathological diagnosis, and lesion's location were gathered. Pearson's chi-square or Fisher's exact test was performed to determine associations between demographic characteristics and different categories of lesions.

RESULTS: Out of 66,546 specimens received, 0.44% (290 specimens) were from patients aged 2 years and younger (27 newborns and 263 infants). The most common category was inflammatory/reactive (44.2%), followed by tumour/tumour-like (42.0%), cystic/pseudocystic (6.6%), and miscellaneous lesions (5.5%). Mucous extravasation cysts (23.4%) and Langerhans cell histiocytosis (7.2%) were the most common histopathological diagnoses. Tumour/tumour-like lesions were significant in newborns (P = .021), and majority were congenital epulis (40.7%). Inflammatory/reactive lesions were significantly higher in male (P = .025) and infants (P = newborns and infants are the key to early detection of lesions.

Matched MeSH terms: Infant, Newborn

Fulltext A retrospective review of tracheal suction at birth in neonates with meconium aspiration syndrome

Manickam D

Med J Malaysia, 1992 Mar;47(1):60-4.

PMID: 1387452

A retrospective study of 54 neonates with Meconium Aspiration Syndrome (MAS) admitted to the Paediatric ICU Penang General Hospital from January 1989-December 1990 was carried out to determine if suction of the trachea at birth was performed in this group of patients. 63% were inborn and 27% outborn. The mean birth weight was 3.2 kg, 83% were ventilated, mean duration of ventilation was five days and the mortality was 24%. 63% had an Apgar Score of less than 5 at 1 min and 65% had thick meconium-stained liquor. Only 48% were intubated and suctioned at birth. Overall tracheal suction rate was low.

Matched MeSH terms: Infant, Newborn

Fulltext A review of Orang Asli newborns admitted to a neonatal unit in a Malaysian general hospital

Kandasamy Y, Somasundram P

Singapore Med J, 2007 Oct;48(10):926-8.

PMID: 17909678

The Orang Asli are the indigenous population in peninsular Malaysia and are in fact a diverse sub-ethnic group with different languages. Our aim was to collect data on Orang Asli newborns, from western and central Pahang, that were admitted to a general hospital with paediatric specialist services.

Matched MeSH terms: Infant, Newborn

Fulltext A review of determinant factors of stillbirths in Malaysia

Rosnah Sutan

Malaysian Journal of Community Health, 2008;14(2):68-77.

MyJurnal

Introduction : Stillbirth is one of the important adverse pregnancy outcomes that has been used as a health indicator for the measurement of the health status of a country especially for its obstetric care management. However, the aetiology of the occurrence of the stillbirth was commonly difficult to identify because of limitations in the classification system.
Methods : A review of existing, available information published up to January 2007 on stillbirths in Malaysia was used to obtain the basic background on the determinant factors of stillbirths. Results : Malaysia, which is a fast developing country, reported a stillbirth rate in the range of 4 to 5 per 1000 births. Almost 30- 40% were recorded as normally formed macerated stillbirths. This was based on a rapid reporting system of perinatal deaths using the modified version of the Wigglesworth’s pathophysiology classification. Those of extreme maternal age (less than 19 years and more than 35 years), those reside in rural areas, of the ‘Bumiputera’ and Indian ethnic groups were at higher risk of stillbirth. On detailed analysis it was seen that the risks of having a normally formed macerated stillbirth increased among those who had a preterm delivery and hypertension. Stillbirth rates were also higher in those with shorter gestational age and in those with parity between 2 and 5. No other factors related to stillbirth were found in this review.
Conclusion : This is a review based on existing published data which has a lot of limitation when it comes to analysing other important factors that might be related with the risk of the stillbirth. However, extreme maternal age and mothers from rural areas are the two factors that were persistently found in almost all literature. When these factors are combined with signs of pre term delivery, they indicate that close monitoring needs to be done.

Matched MeSH terms: Infant, Newborn

A review of experimental evidences that could warn of possible dangers of alcohol consumption by pregnant mothers

Chaudhuri JD

Indian J Med Sci, 2000 Dec;54(12):545-54.

PMID: 11354820

Most of the features of fetal alcohol syndrome (FAS) have been replicated in experimental models. They provide an insight into the effects of alcohol on the developing embryo, however, satisfactory explanations for these effects are still not available. Certain maternal characteristics of children with FAS have been identified. However, it is not absolute as at times the most unlikely women are susceptible to problems of maternal alcoholism. The levels of awareness of FAS among the general public and health workers are inadequate. Measures need to be taken to remedy this condition.

Matched MeSH terms: Infant, Newborn

A review of patients with skeletal tuberculosis treated at the University Hospital, Kuala Lumpur

Silva JF

Int Orthop, 1980;4(2):79-81.

PMID: 7429684 DOI: 10.1007/bf00271088

Two hundred and nineteen patients with skeletal tuberculosis have been reviewed analysing the site of the lesion and the treatment given. Operative management is advocated since the results of this approach are encouraging.

Matched MeSH terms: Infant, Newborn

A review of perinatal mortality in Peninsular Malaysia from 1980 to 1989

Musa Mohd Nordin, Mohd Sham Kasim, Wong, Swee Lan

Malaysian Journal of Child Health, 1993;5(1):9-19.

MyJurnal

An analysis of perinatal statistics in Peninsular Malaysia from 1980 — 1989 was undertaken. The Perinatal Mortality Rate showed a 42% decrease over the 10 year period. The Perinatal Mortality Rate was higher among the Indian and Malay ethnic groups compared to the Chinese. This was largely contributed by the higher Stillbirth rate in the former 2 ethnic groups. The Indians have the highest rate of low birthweight babies. There is a decline in the rate of low birthweight babies born over the studied decade. The major causes of early neonatal mortality included problems asociated with prematurity, asphyxia neonatorum, septicaemia and congenital anomalies. Further epi-demiological research is required to identify other riskfactors which contribute to this ethnic biased perinatal mortality rates. Besides intensifying and upgrading current multifaceted approaches, interventional strategies need to be directed to the identified high risk groups. (Copied from article).

Matched MeSH terms: Infant, Newborn

A review of tetanus neonatorum in Singapore during the years 1946-1950

Loh SG

Med J Malaya, 1951;5.

Report on 174 cases of tetanus neonatorum collected between 1946 and 1950 in the General Hospital, Singapore. There is a marked reduction in the incidence, which is attributed to a better maternity service. The results of treatment are bad – with a mortality of 90% of cases.

Matched MeSH terms: Infant, Newborn

A review of the serological results obtained in a routine diagnostic laboratory for Mycoplasma pneumoniae infections

Tay ST, Cheong YM

Malays J Pathol, 1995 Jun;17(1):35-7.

PMID: 8907003

The results of a Mycoplasma pneumoniae serology test performed routinely at the Bacteriology Division, Institute for Medical Research were reviewed. A total of 1402 patients were screened over a period of 4 years (January, 1990-December, 1993), of which 327 (23.3%) were seropositive. The seropositivity rates among Malays, Chinese and Indians were 25.2, 25.4 and 17.8% respectively. The male to female ratio was 1:1. The age specific rate was highest amongst patients of the 6-12 years (35.1%) followed by the 13-20 years age groups (35.0%). In general, infection with M. pneumoniae appears to be relatively common in this country.

Matched MeSH terms: Infant, Newborn

Fulltext A serological study of cytomegalovirus and herpes simplex virus infections in Peninsular Malaysia

Tan DS, Stern H

Bull World Health Organ, 1981;59(6):909-12.

PMID: 6279323

Healthy Malaysians from various parts of Peninsular Malaysia were examined for CF antibodies against cytomegalovirus (CMV) and herpes simplex virus (HSV) type 2. CMV antibodies were detected in 1114 out of 1556 persons (71.6%) and HSV antibodies were detected in 954 persons out of 1554 (61.4%). The age distribution patterns were similar for the two infections, with maximum prevalence at 5 - 14 years of age. Prevalence was higher in women than in men. There were no significant differences among the Malay, Chinese, and Indian groups of the population with respect to CMV, 72 - 78% possessing antibodies, but in the case of HSV, 76% of the Chinese had antibodies, compared with 57 - 60% of the Malays and Indians. More than 90% of newborn infants had CMV and HSV CF antibodies, confirming the highly immune status of childbearing women in Malaysia. No CMV-specific IgM was detected in the Malaysian neonates examined but this does not exclude the possibility of congenital infection.

Matched MeSH terms: Infant, Newborn

A single centre study on birth of children with transfusion-dependent thalassaemia in Malaysia and reasons for ineffective prevention

Ngim CF, Ibrahim H, Lai NM, Ng CS

Prenat Diagn, 2015 Jan;35(1):51-9.

PMID: 25156332 DOI: 10.1002/pd.4484

We aimed to identify factors contributing to ineffective prevention of thalassaemia in Malaysia by studying events leading to the births of children with transfusion-dependent thalassaemia (TDT) including their parents' reproductive choices.

Matched MeSH terms: Infant, Newborn

Fulltext A structural equation model of the determinants of malnutrition among children in rural Kelantan, Malaysia

Cheah WL, Wan Muda WAM, Zamh ZH

Rural Remote Health, 2010;10(1):1248.

PMID: 20184392

Many studies had shown that poor growth in children is associated with malnutrition. The underlying factors are diverse, multisectoral and interrelated, ranging from biological to social, cultural and economically related. Because the highest levels of under-nutrition worldwide are found in South Asia, it is essential that policymakers in the region understand the underlying determinants, in order to design effective public health intervention programs. This is especially so if public resources are limited. The purpose of this cross-sectional study was to examine causal relationships among the biological, behavioural and environmental factors related to malnutrition in children aged 5 years and under.

Matched MeSH terms: Infant, Newborn

Fulltext A study of cleft lip and palate in neonates born in a large Malaysian maternity hospital over a 2-year period

Boo NY, Arshad AR

Singapore Med J, 1990 Feb;31(1):59-62.

PMID: 2333547

Out of 52,379 babies delivered in the Maternity Hospital, Kuala Lumpur, over a 2-year period, 64 were born with cleft lip and/or palates. The rate of occurrence of cleft was 1.24 per 1000 livebirths or 1.20 per 1000 deliveries. The Chinese babies had the highest incidence (1.9 per 1000 deliveries) while the Malays had the lowest (0.98 per 1000 deliveries). The most common type was unilateral cleft of the primary and secondary palates. Among the Indian babies, cleft of the secondary palate was most common. 18.8 percent of all the affected babies had positive family history of cleft. 10.9% of the mothers of affected babies had positive history of drug ingestion especially Chinese herbs during pregnancy. Associated congenital abnormalities occurred in 15.6% of the babies with cleft lip and/or palate.

Matched MeSH terms: Infant, Newborn

A study of current infant feeding practices in rural North Malaysia as a basis for determining needs in nutrition education

Pathmanathan I

Southeast Asian J. Trop. Med. Public Health, 1975 Sep;6(3):402-6.

PMID: 1241162

In a study of infant feeding practices in 95 infants aged three months and six months in the rural, predominantly Malay district of Kubang Pasu, which is recently undergoing rapid economic development consequent on the introduction of improved agricultural techniques in rice farming, it was found that approximately 75% of infants in both age groups were wholly or partially breast fed, modified powered milk being the milk food of most of the others. Semisolids were introduced early in the form of commercial prepacked cereals. It is suggested that medical officers of health recognising local socioeconomic and cultural changes that might affect health behavior can initiate simple studies of this type to identify local needs in health education. In circumstances such as this where a still popular beneficial traditional practice like breast feeding might be at risk of losing popularity in the face of socioeconomic development in the community it is suggested that the most useful educational effort regarding infant nutrition would be to preserve breast feeding.

Matched MeSH terms: Infant, Newborn

A study of immunoglobulin levels among Singapore infants and children

Paul FM, Leng T, Wee R

J Singapore Paediatr Soc, 1972 Apr;14(1):1-16.

PMID: 4626321

Matched MeSH terms: Infant, Newborn

Fulltext A study of liver reserves of vitamin A in Malaysians

Chandrasekharan N

Malays J Pathol, 1981 Aug;4:43-7.

PMID: 7186602

Matched MeSH terms: Infant, Newborn

Fulltext A study of perforating eye injuries at the Ophthalmology Department, National University of Malaysia

Zainal M, Goh PP

Med J Malaysia, 1997 Mar;52(1):12-6.

PMID: 10968048

One hundred and sixty seven (167) perforating eye injuries involving 159 patients were analyzed in a retrospective study over a three-year period. The degree of blindness and their associated factors were determined. Most patients were in the first three decades of life and were males. One hundred and seven (64%) eyes had vision of 3/60 or worse at initial assessment. Of these only 45% of eyes had improved vision to 6/36 or better at six months of follow-up. Fifty-five per cent of eyes were blind. The only significant associated factor identified was the extent of injury. Age, time interval and mechanism of injury were not significant factors.

Matched MeSH terms: Infant, Newborn

A study of sudden natural deaths in medico legal autopsies in University Malaya Medical Centre (UMMC), Kuala Lumpur

Kumar V, San KP, Idwan A, Shah N, Hajar S, Norkahfi M

J Forensic Leg Med, 2007 Apr;14(3):151-4.

PMID: 16914354

The main aim of this study is to determine the causes and the epidemiological aspects of sudden natural deaths. Data were collected from 545 sudden natural autopsies in UMMC, Kuala Lumpur over a five-year period, from 1st January 2000 to 31st December 2004. There were 475 males and 70 females. The largest number of sudden natural deaths was in the age group of 41-50 years. 35.8%, 30.5% and 11.7% of the patients were Chinese, Indian and Malay, respectively. A majority of the patients were married (59.8%) and came from the semiskilled-unskilled group (30.6%). The monthly distribution was almost constant. Cardiovascular diseases were the most important cause contributing 64.9% in sudden natural deaths.

Matched MeSH terms: Infant, Newborn

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