Displaying publications 81 - 100 of 137 in total

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  1. Daub NA, Aziz F, Mhamad SA, Chee DNA, Jaafar J, Yusof N, et al.
    Environ Sci Pollut Res Int, 2024 Mar;31(11):16629-16641.
    PMID: 38321283 DOI: 10.1007/s11356-024-32261-w
    In response to the escalating global issue of microbial contamination, this study introduces a breakthrough photocatalyst: bismuth ferrite-activated carbon (BFO-AC) for visible light-driven disinfection, specifically targeting the Gram-positive bacterium Staphylococcus aureus (S. aureus). Employing an ultrasonication method, we synthesized various BFO-AC ratios and subjected them to comprehensive characterization. Remarkably, the bismuth ferrite-activated carbon 1:1.5 ratio (BA 1:1.5) nanocomposite exhibited the narrowest band gap of 1.86 eV. Notably, BA (1:1.5) demonstrated an exceptional BET surface area of 862.99 m2/g, a remarkable improvement compared to pristine BFO with only 27.61 m2/g. Further investigation through FE-SEM unveiled the presence of BFO nanoparticles on the activated carbon surface. Crucially, the photocatalytic efficacy of BA (1:1.5) towards S. aureus reached its zenith, achieving complete inactivation in just 60 min. TEM analysis revealed severe damage and rupture of bacterial cells, affirming the potent disinfection capabilities of BA (1:1.5). This exceptional disinfection efficiency underscores the promising potential of BA (1:1.5) for the treatment of contaminated water sources. Importantly, our results underscore the enhanced photocatalytic performance with an increased content of activated carbon, suggesting a promising avenue for more effective microorganism inactivation.
  2. Abdulsalam M, Che Man H, Goh PS, Yunos KF, Zainal Abidin Z, Isma M I A, et al.
    Polymers (Basel), 2020 Mar 03;12(3).
    PMID: 32138186 DOI: 10.3390/polym12030549
    This study focused on developing a hydrophilic hybrid polyvinylidene fluoride (PVDF)-polyethylene glycol (PEG) hollow membrane by incorporating Nano-magnesium oxide (NMO) as a potent antifouling mediator. The Nano-hybrid hollow fibers with varied loading of NMO (0 g; 0.25 g; 0.50 g; 0.75 g and 1.25 g) were spun through phase inversion technique. The resultants Nano-hybrid fibers were characterized and compared based on SEM, EDX, contact angle, surface zeta-potential, permeability flux, fouling resistance and color rejection from palm oil mill effluent (POME). Noticeably, the permeability flux, fouling resistance and color rejection improved with the increase in NMO loading. PVDF-PEG with 0.50 g-NMO loading displayed an outstanding performance with 198.35 L/m2·h, 61.33 L/m2·h and 74.65% of water flux, POME flux and color rejection from POME, respectively. More so, a remarkable fouling resistance were obtained such that the flux recovery, reversible fouling percentage and irreversible fouling percentage remains relatively steady at 90.98%, 61.39% and 7.68%, respectively, even after 3 cycles of continuous filtrations for a total period of 9 h. However, at excess loading of 0.75 and 1.25 g-NMO, deterioration in the flux and fouling resistance was observed. This was due to the agglomeration of nanoparticles within the matrix structure at the excessive loading.
  3. Muhammad A, Wan Mohammad WMZ, Idris SRA, Ismail AF
    Cureus, 2024 Feb;16(2):e53521.
    PMID: 38445119 DOI: 10.7759/cureus.53521
    INTRODUCTION: Safety has become paramount to ensure that scuba diving continues to expand into new markets, with minimal risks, and that scuba diving translates into a safe and relaxed adventure in response to growing market demands. Research focusing on assessing the knowledge, awareness, and practices (KAP) regarding safety and emergency response among scuba divers has been limited, and there is a need for validated assessment tools in this area.

    METHODS: This study involved 555 scuba divers in Malaysia, and the questionnaire underwent a thorough development and validation process, including content and face validity assessments, as well as exploratory factor analysis. The validation of the knowledge domain was conducted using Item Response Theory (IRT) analysis, while awareness and practice were validated through exploratory and confirmatory factor analyses (EFA and CFA).

    RESULTS: The content validity of the instrument was confirmed, with all items scoring over 80% for Item Content Validity Index (I-CVI), Scale Content Validity Index (S-CVI), and Scale Content Validity Index/Average (S-CVI/AVE). The initial draft comprises three domains: knowledge, awareness, and practice. Knowledge items were analyzed using IRT and demonstrated acceptable difficulty and discrimination levels. For the awareness and practice domains, EFA showed a Kaiser-Meyer-Olkin measure (KMO) of 0.83 and 0.79, respectively, with a significant Bartlett's test of Sphericity (P < 0.001). EFA yielded three factors for both awareness and practice domains with a total of 12 items for awareness and 13 items for practice, with satisfactory factor loadings (≥0.3). The final model of CFA showed good fits for both awareness and practice domains in terms of absolute, parsimonious, and comparative measures. The composite reliability of awareness was acceptable with Raykov's rho of 0.71, whereas the practice domain fell slightly below the acceptable threshold at 0.55. This was attributed to low factor loading and a limited number of items within each factor. The final questionnaire now consists of 20 items for knowledge, 10 items for awareness, and 12 items for the practice domain.

    CONCLUSION: The results of this validation and reliability study indicate that the newly developed questionnaire possesses favorable psychometric properties for assessing KAP related to safety and emergency response in the scuba diving context. This research is essential for harmonizing the perspectives of crucial stakeholders within the recreational scuba diving industry.

  4. Wan Ikhsan SN, Yusof N, Mat Nawi NI, Bilad MR, Shamsuddin N, Aziz F, et al.
    Polymers (Basel), 2021 Jan 30;13(3).
    PMID: 33573140 DOI: 10.3390/polym13030441
    Membrane filtration is an attractive process in water and wastewater treatment, but largely restricted by membrane fouling. In this study, the membrane fouling issue is addressed by developing polyethersulfone (PES)-based mixed matrix membranes (MMMs) with the incorporation of hydrophilic nanoparticles as an additive. Ultrafiltration MMMs were successfully fabricated by incorporating different loadings of halloysite nanotube-ferrihydrates (HNT-HFO) into a polyethersulfone (PES) matrix and their performance was evaluated for the separation of bovine serum albumin (BSA) solution and oil/water emulsion. The results show that wettability is endowed to the membrane by introducing the additive aided by the presence of abundant -OH groups from the HFO. The loading of additive also leads to more heterogeneous surface morphology and higher pure water fluxes (516.33-640.82 L/m2h) more than twice that of the pristine membrane as reference (34.69 L/m2h) without affecting the rejection. The MMMs also provide much enhanced antifouling properties. The filtration results indicate that the flux recovery ratio of the modified membrane reached 100% by washing with only distilled water and a total flux recovery ratio of >98% ± 0.0471 for HNT-HFO-loaded membranes in comparison with 59% ± 0.0169 for pristine PES membrane.
  5. Nayak V, Jyothi MS, Balakrishna RG, Padaki M, Ismail AF
    ChemistryOpen, 2015 Jun;4(3):278-87.
    PMID: 26246989 DOI: 10.1002/open.201402133
    Herein we present a new approach for the complete removal of Cr(VI) species, through reduction of Cr(VI) to Cr(III), followed by adsorption of Cr(III). Reduction of chromium from water is an important challenge, as Cr(IV) is one of the most toxic substances emitted from industrial processes. Chitosan (CS) thin films were developed on plain polysulfone (PSf) and PSf/TiO2 membrane substrates by a temperature-induced technique using polyvinyl alcohol as a binder. Structure property elucidation was carried out by X-ray diffraction, microscopy, spectroscopy, contact angle measurement, and water uptake studies. The increase in hydrophilicity followed the order: PSf < PSf/TiO2 < PSf/TiO2/CS membranes. Use of this thin-film composite membrane for chromium removal was investigated with regards to the effects of light and pH. The observations reveal 100 % reduction of Cr(VI) to Cr(III) through electrons and protons donated from OH and NH2 groups of the CS layer; the reduced Cr(III) species are adsorbed onto the CS layer via complexation to give chromium-free water.
  6. Khoo YS, Lau WJ, Liang YY, Karaman M, Gürsoy M, Ismail AF
    J Adv Res, 2022 Feb;36:39-49.
    PMID: 35127163 DOI: 10.1016/j.jare.2021.06.011
    INTRODUCTION: Nanomaterials aggregation within polyamide (PA) layer of thin film nanocomposite (TFN) membrane is found to be a common issue and can negatively affect membrane filtration performance. Thus, post-treatment on the surface of TFN membrane is one of the strategies to address the problem.

    OBJECTIVE: In this study, an eco-friendly surface modification technique based on plasma enhanced chemical vapour deposition (PECVD) was used to deposit hydrophilic acrylic acid (AA) onto the PA surface of TFN membrane with the aims of simultaneously minimizing the PA surface defects caused by nanomaterials incorporation and improving the membrane surface hydrophilicity for reverse osmosis (RO) application.

    METHODS: The TFN membrane was first synthesized by incorporating 0.05 wt% of functionalized titania nanotubes (TNTs) into its PA layer. It was then subjected to 15-s plasma deposition of AA monomer to establish extremely thin hydrophilic layer atop PA nanocomposite layer. PECVD is a promising surface modification method as it offers rapid and solvent-free functionalization for the membranes.

    RESULTS: The findings clearly showed that the sodium chloride rejection of the plasma-modified TFN membrane was improved with salt passage reduced from 2.43% to 1.50% without significantly altering pure water flux. The AA-modified TFN membrane also exhibited a remarkable antifouling property with higher flux recovery rate (>95%, 5-h filtration using 1000 mg/L sodium alginate solution) compared to the unmodified TFN membrane (85.8%), which is mainly attributed to its enhanced hydrophilicity and smoother surface. Furthermore, the AA-modified TFN membrane also showed higher performance stability throughout 12-h filtration period.

    CONCLUSION: The deposition of hydrophilic material on the TFN membrane surface via eco-friendly method is potential to develop a defect-free TFN membrane with enhanced fouling resistance for improved desalination process.

  7. Seah MQ, Ng ZC, Lai GS, Lau WJ, Al-Ghouti MA, Alias NH, et al.
    Chemosphere, 2024 Apr 09;356:141960.
    PMID: 38604517 DOI: 10.1016/j.chemosphere.2024.141960
    Pesticides are used in agriculture to protect crops from pathogens, insects, fungi and weeds, but the release of pesticides into surface/groundwater by agriculture runoff and rain has raised serious concerns not only for the environment but also for human health. This study aimed to investigate the impact of surface properties on the performance of seven distinct membrane types utilized in nanofiltration (NF), reverse osmosis (RO) and forward osmosis (FO) processes in eliminating multiple pesticides from spiked water. Out of the membranes tested, two are self-fabricated RO membranes while the rest are commercially available membranes. Our results revealed that the self-fabricated RO membranes performed better than other commercial membranes (e.g., SW30XLE, NF270, Duracid and FO) in rejecting the targeted pesticides by achieving at least 99% rejections regardless of the size of pesticides and their log Kow value. Despite the marginally lower water flux exhibited by the self-fabricated membrane compared to the commercial BW30 membrane, its exceptional ability to reject both mono- and divalent salts renders it more apt for treating water sources containing not only pesticides but also various dissolved ions. The enhanced performance of the self-fabricated RO membrane is mainly attributed to the presence of a hydrophilic interlayer (between the polyamide layer and substrate) and the incorporation of hydrophilic nanosheets in tuning its surface characteristics. The findings of the work provide insight into the importance of membrane surface modification for the application of not only the desalination process but also for the removal of contaminants of emerging concern.
  8. Adam MR, Salleh NM, Othman MHD, Matsuura T, Ali MH, Puteh MH, et al.
    J Environ Manage, 2018 Oct 15;224:252-262.
    PMID: 30055458 DOI: 10.1016/j.jenvman.2018.07.043
    Adsorption is one of the most efficient ways to remove heavy metal from wastewater. In this study, the adsorptive removal of hexavalent chromium, Cr (VI) from aqueous solution was investigated using natural zeolite, clinoptilolite, in the form of hollow fibre ceramic membrane (HFCM). The HFCM sample was prepared using phase inversion-based extrusion technique and followed by sintering process at different sintering temperatures in the range of 900-1050 °C. The fabricated HFCM was characterised using scanning electron microscopy (SEM), contact angle, water permeability, and mechanical strength for all HFCMs sintered at different temperatures. The adsorption and filtration test of Cr (VI) were performed using an in-house water permeation set up with a dead-end cross-flow permeation test. An asymmetric structure with sponge- and finger-like structures across the cross-section of HFCM was observed using SEM. Based on the characterisation data, 1050 °C was chosen to be the best sintering temperature as the water permeability and mechanical strength of this HFCM were 29.14 L/m2∙h and 50.92 MPa, respectively. The performance of the HFCM in adsorption/filtration was 44% of Cr (VI) removal at the Cr (VI) concentration of 40 mg/L and pH 4. In addition, the mathematical model was also performed in simulating the experimental data obtained from this study. All in all, the natural zeolite-based HFCM has a potential as a single-step Cr (VI) removal by membrane adsorption for the wastewater treatment.
  9. Makhtar SNNM, Rahman MA, Ismail AF, Othman MHD, Jaafar J
    Environ Sci Pollut Res Int, 2017 Jul;24(19):15918-15928.
    PMID: 28589281 DOI: 10.1007/s11356-017-9405-7
    This work discusses the preparation and characterizations of glass hollow fiber membranes prepared using zeolite-5A as a starting material. Zeolite was formed into a hollow fiber configuration using the phase inversion technique. It was later sintered at high temperatures to burn off organic materials and change the zeolite into glass membrane. A preliminary study, that used thermogravimetric analysis (TGA), X-ray diffraction (XRD), and Fourier transform infrared (FTIR), confirmed that zeolite used in this study changed to glass at temperatures above 1000 °C. The glass hollow fiber membranes prepared using the phase inversion technique has three different microstructures, namely (i) sandwich-like structure that originates from inner layer, (ii) sandwich-like that originates from outer layer, and (iii) symmetric sponge like. These variations were influenced by zeolite weight loading and the flow rate of water used to form the lumen. The separation performances of the glass hollow fiber membrane were studied using the pure water permeability and the rejection test of bovine serum albumin (BSA). The glass hollow fiber membrane prepared from using 48 wt% zeolite loading and bore fluid with 9 mL min(-1) flow rate has the highest BSA rejection of 85% with the water permeability of 0.7 L m(-2) h(-1) bar(-1). The results showed that the separation performance of glass hollow fiber membranes was in the ultrafiltration range, enabled the retention of solutes with molecular sizes larger than 67 kDa such as milk proteins, endotoxin pyrogen, virus, and colloidal silica.
  10. Kamaludin R, Othman MHD, Kadir SHSA, Khan J, Ismail AF, Rahman MA, et al.
    Environ Sci Pollut Res Int, 2023 Jan;30(1):259-273.
    PMID: 35902521 DOI: 10.1007/s11356-022-22121-w
    Various treatments of choice are available to overcome contamination of bisphenol A (BPA) in the environment including membrane technologies; however, the treatment still releases contaminants that threaten the human being. Therefore, the present study is conducted to investigate the degradation of BPA by recently developed visible-light-driven photocatalytic nitrogen-doping titanium dioxide (N-doped TiO2) dual-layer hollow fibre (DLHF) membrane and its efficiency in reducing the level of BPA in contaminated water. Fabricated with suitable polymer/photocatalyst (15/7.5 wt.%) via co-extrusion spinning method, the DLHF was characterized morphologically, evaluated for BPA degradation by using submerged photocatalytic membrane reactor under visible light irradiations followed by the investigation of intermediates formed. BPA exposure effects were accessed by immunohistochemistry staining of gastrointestinal sample obtained from animal model. BPA has been successfully degraded up to 72.5% with 2 intermediate products, B1 and B2, being identified followed by total degradation of BPA. BPA exposure leads to the high-intensity IHC staining of Claudin family which indicated the disruption of small intestinal barrier (SIB) integrity. Low IHC staining intensity of Claudin family in treated BPA group demonstrated that reducing the level of BPA by N-doped TiO2 DLHF is capable of protecting the important component of SIB. Altogether, the fabricated photocatalytic DLHF membrane is expected to have an outstanding potential in removing BPA and its health effect for household water treatment to fulfil the public focus on the safety of their household water and their need to consume clean water.
  11. Mohanadas HP, Nair V, Doctor AA, Faudzi AAM, Tucker N, Ismail AF, et al.
    Ann Biomed Eng, 2023 Nov;51(11):2365-2383.
    PMID: 37466879 DOI: 10.1007/s10439-023-03322-x
    Additive Manufacturing is noted for ease of product customization and short production run cost-effectiveness. As our global population approaches 8 billion, additive manufacturing has a future in maintaining and improving average human life expectancy for the same reasons that it has advantaged general manufacturing. In recent years, additive manufacturing has been applied to tissue engineering, regenerative medicine, and drug delivery. Additive Manufacturing combined with tissue engineering and biocompatibility studies offers future opportunities for various complex cardiovascular implants and surgeries. This paper is a comprehensive overview of current technological advancements in additive manufacturing with potential for cardiovascular application. The current limitations and prospects of the technology for cardiovascular applications are explored and evaluated.
  12. Mohamed MA, Salleh WN, Jaafar J, Ismail AF, Abd Mutalib M, Jamil SM
    Carbohydr Polym, 2015 Nov 20;133:429-37.
    PMID: 26344299 DOI: 10.1016/j.carbpol.2015.07.057
    In this work, an environmental friendly RC/N-TiO2 nanocomposite thin film was designed as a green portable photocatalyst by utilizing recycled newspaper as sustainable cellulose resource. Investigations on the influence of N-doped TiO2 nanorods incorporation on the structural and morphological properties of RC/N-TiO2 nanocomposite thin film are presented. The resulting nanocomposite thin film was characterized by FESEM, AFM, FTIR, UV-vis-NIR spectroscopy, and XPS analysis. The results suggested that there was a remarkable compatibility between cellulose and N-doped TiO2 nanorods anchored onto the surface of the RC/N-TiO2 nanocomposite thin film. Under UV and visible irradiation, the RC/N-TiO2 nanocomposite thin film showed remarkable photocatalytic activity for the degradation of methylene blue solution with degradation percentage of 96% and 78.8%, respectively. It is crucial to note that the resulting portable photocatalyst produced via an environmental and green technique in its fabrication process has good potential in the field of water and wastewater treatment application.
  13. Zailani MZ, Ismail AF, Sheikh Abdul Kadir SH, Othman MH, Goh PS, Hasbullah H, et al.
    J Biomed Mater Res A, 2017 05;105(5):1510-1520.
    PMID: 28000366 DOI: 10.1002/jbm.a.35986
    In this study, poly (1,8-octanediol citrate) (POC) was used to modify polyethersulfone (PES)-based membrane to enhance its hemocompatibility. Different compositions of POC (0-3%) were added into the polyethersulfone (PES) dope solutions and polyvinylpyrrolidone (PVP) was used as pore forming agent. The hemocompatible POC modified PES membranes were fabricated through phase-inversion technique. The prepared membranes were characterized using attenuated total reflectance-Fourier transform infrared (ATR-FTIR), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), Atomic-force microscopy (AFM), contact angle, Zeta-potential, membrane porosity and pore size and pure water flux (PWF) and BSA rejection. The hemocompatibility of the modified PES membranes was evaluated by human serum fibrinogen (FBG) protein adsorption, platelet adhesion, activated partial thromboplastin time (APTT) and prothrombin time (PT), and thrombin-antithrombin III (TAT), complement (C3a and C5a) activation and Ca2+ absorption on membrane. Results showed that by increasing POC concentration, FBG adsorption was reduced, less platelets adhesion, prolonged APTT and PT, lower TAT, C5a and C3a activation and absorb more Ca2+ ion. These results indicated that modification of PES with POC has rendered improved hemocompatibility properties for potential application in the field of blood purification, especially in hemodialysis. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1510-1520, 2017.
  14. Abidin MNZ, Goh PS, Ismail AF, Said N, Othman MHD, Hasbullah H, et al.
    Carbohydr Polym, 2018 Dec 01;201:257-263.
    PMID: 30241818 DOI: 10.1016/j.carbpol.2018.08.069
    Portable dialysis is a need to implement daily and nocturnal hemodialysis. To realize portable dialysis, a dialysate regeneration system comprising superior adsorbents is required to regenerate the used dialysate. This study aims to develop a nano-adsorbent, derived from corn starch for urea removal. Oxidized starch nanoparticles (oxy-SNPs) were prepared via liquid phase oxidation, followed by chemical dissolution and non-solvent precipitation. The oxy-SNPs possessed Z-average size of 177.7 nm with carbonyl and carboxyl contents of 0.068 and 0.048 per 100 glucose units, respectively. The urea adsorption achieved the equilibrium after 4 h with 95% removal. The adsorption mechanism fitted Langmuir isotherm while the adsorption kinetics obeyed pseudo-second-order model. This new material has a maximum adsorption capacity of 185.2 mg/g with a rate constant of 0.04 g/mg.h. Moreover, the oxy-SNPs exhibited the urea uptake recovery of 91.6%. Oxy-SNPs can become a promising adsorbent for dialysate regeneration system to remove urea.
  15. Salimi E, Ghaee A, Ismail AF, Karimi M
    Int J Biol Macromol, 2018 Sep;116:364-377.
    PMID: 29709537 DOI: 10.1016/j.ijbiomac.2018.04.137
    The main aim of this study was to evaluate the suitability of sulfonated alginate as a modifying agent to enhance the hemocompatibility of self-fabricated polyethersulfone (PES) hollow fiber membrane for blood detoxification. Sodium alginate was sulfonated with a degree of 0.6 and immobilized on the membrane via surface amination and using glutaraldehyde as cross-linking agent. Coating layer not only improved the membrane surface hydrophilicity, but also induced -39.2 mV negative charges on the surface. Water permeability of the modified membrane was enhanced from 67 to 95 L/m2·h·bar and flux recovery ratio increased more than 2-fold. Furthermore, the modified membrane presented higher platelet adhesion resistance (reduced by more than 90%) and prolonged coagulation time (35 s for APTT and 14 s for PT) in comparison with the pristine PES hollow fiber membrane, which verified the improved anti-thrombogenicity of the modified membrane. On the other hand, obtained membrane after 3 h coating could remove up-to 60% of the uremic toxins. According to the obtained data, sulfonated alginate can be a promising modifying agent for the future blood-contacting membrane and specially blood purification issues.
  16. Mansur S, Othman MHD, Ismail AF, Kadir SHSA, Goh PS, Hasbullah H, et al.
    Mater Sci Eng C Mater Biol Appl, 2019 Jun;99:491-504.
    PMID: 30889724 DOI: 10.1016/j.msec.2019.01.092
    Polyurethane (PU) with three different functional groups: carboxyl, hydroxyl and sulphonyl group on its molecular structure were synthesised in this work. The synthesised material suppresses blood clotting and exhibits anticoagulant characteristics due to the presence of the important anionic groups. The synthesised PU was blended with polyethersulphone (PES) and fabricated into flat-sheet membrane to study the physico-chemical and biocompatibility properties of the PES membrane for blood purification application. PES-PU flat-sheet membranes were fabricated via the dry-wet phase separation technique. Different loading of PU (0, 1, 2, 3, 4, and 5%) blended with PES was studied and compared. Based on the in-vitro biocompatibility analysis of the membrane, it can be suggested that the membrane incorporated with PU has better anticoagulant properties compared to the pristine PES membrane. PU incorporation prolonged the clotting time, decreased the formation of thrombin, decreased soluble complement component 3a (C3a) generation and suppressed platelet adhesion and aggregation. The anionic groups on the membrane surface might bind to coagulation factors (antithrombin) and the calcium ions, Ca2+ and thus improve anticoagulant ability. Based on both physico-chemical and in-vitro studied, 4% loading of PU is the optimum loading for incorporation with PES membrane. These results suggested that the blended PES-PU membranes with good haemocompatibility allowed practical application in the field of blood purification.
  17. Ismail AF, Tengku Azmi TMA, Malek WMSWA, Mallineni SK
    J Indian Soc Pedod Prev Dent, 2021 4 23;39(1):2-8.
    PMID: 33885380 DOI: 10.4103/jisppd.jisppd_36_21
    Objective: The objective was to assess the effectiveness of multisensory-adapted environment on children's behavior toward dental treatment, specifically in special need children.

    Materials and Methods: The main health databases were selected such as SCOPUS, Medline, CINAHL, and Dentistry and Oral Sciences. A set of keywords was defined to identify the relevant article were (i.e., Snoezelen OR Multisensory OR sensory-adapted and Dentistry OR Oral). The articles were selected and extracted by two reviewers based on the Preferred Reporting Items for Systematic Review and Meta-analysis guidelines and some predetermined exclusion criteria. Furthermore, the risk of bias assessment was done.

    Results: A total of 317 papers were selected at the first phase from SCOPUS (97 papers), Medline (108 papers), CINAHL (110 papers), and Dentistry and Oral Sciences (2 papers). After applying the inclusion and exclusion criteria and duplicated papers were removed, only four eligible papers were selected for final synthesis.

    Conclusions: Multisensory-adapted dental environment effectively improves oral health behavior among special needs children in terms of physiological changes, behaviors, pain, and sensory discomfort. Thus, the clinician may introduce this approach in their clinical settings.

  18. Ismail AF, Adnan NH, Suhaidi NNS, Mokhtar IW, Yusof MYPM, Mallineni SK
    J Indian Soc Pedod Prev Dent, 2024 Jan 01;42(1):64-70.
    PMID: 38616429 DOI: 10.4103/jisppd.jisppd_47_24
    AIM: This study aimed to validate the accuracy of dental age (DA) based on the dental development of permanent teeth in children with special needs using Demirjian, Willems, and London Atlas methods and to correlate the dental and chronological age (CA) of children with special needs in Malaysia.

    MATERIALS AND METHODS: The panoramic radiographic images belonging to children with special needs from the two teaching dental hospitals in Malaysia aged between 5 and 16 years were included in the study. The evaluation was performed by two observers using three methods (London Atlas, Demirjian, and Willems methods) to estimate the accurate DA. The outcome was determined by comparing the mean of the DA and CA.

    RESULTS: A total of 52 panoramic radiographs were available for the analysis. The London Atlas and Demirjian methods overestimated the DA with a mean of 0.05 and 0.20 years, respectively, while the Willems method underestimated by 0.19 years. The London Atlas method was highly precise and accurate, while Demirjian and Willems methods were the least precise and accurate.

    CONCLUSION: The London Atlas method of DA estimation is highly accurate and valid for children with special needs in the Malaysian population, followed by the Willems and Demirjian methods.

  19. Dantham P, Nuvvula S, Ismail AF, Akkilagunta S, Mallineni SK
    Dent Med Probl, 2024;61(2):209-216.
    PMID: 38668708 DOI: 10.17219/dmp/156655
    BACKGROUND: Several risk factors contribute to the development of dental caries in children, including sociodemographic, dietary, oral hygiene-related and other miscellaneous factors. Maternal smoking was highly associated with dental caries when compared to smoking by fathers or other household members.

    OBJECTIVES: The aim of the study was to determine the prevalence of dental caries and their association with exposure to environmental tobacco smoke (ETS) among 5- to 10-year-old students attending private and government schools.

    MATERIAL AND METHODS: A cross-sectional analytical study was conducted among schoolchildren. Data was collected from the primary caregivers using a pre-tested form to assess the ETS exposure under 5 domains based on history: antenatal exposure; exposure during the index period; exposure in the school neighborhood; exposure in restaurants/roadside stalls; and exposure in bus stops/railway stations. Dental caries was assessed based on the World Health Organization (WHO) guidelines from 1997. The association was reported using prevalence ratios (PRs) (95% confidence interval (CI)).

    RESULTS: Data was obtained from 211 schoolchildren attending government (39.8%) and private schools (60.2%). The overall prevalence (95% CI) of dental caries was 49.3% (42.5-56.1%). Among all the risk factors evaluated in the study, exposure to ETS was associated with a significantly increased risk of dental caries. The adjusted prevalence ratio (APR) of ETS exposure varied with the mother's educational status and high sugar exposure, although this was statistically insignificant.

    CONCLUSIONS: The prevalence of dental caries among schoolchildren aged 5 to 10 years in the city was moderate and similar to the national average. Among the risk factors assessed in the study, antenatal exposure to ETS was found to significantly increase the prevalence of dental caries by 41% after adjusting for other factors. Therefore, it is important to educate parents on the causal role of ETS exposure in dental caries.

  20. Zainol Abidin MN, Goh PS, Said N, Ismail AF, Othman MHD, Hasbullah H, et al.
    ACS Appl Mater Interfaces, 2020 Jul 22;12(29):33276-33287.
    PMID: 32589391 DOI: 10.1021/acsami.0c08947
    The development of wearable artificial kidney demands an efficient dialysate recovery, which relies upon the adsorption process. This study proposes a solution to solve the problem of competitive adsorption between the uremic toxins by employing two adsorptive components in a membrane separation process. Dual-layer hollow fiber (DLHF) membranes, which are composed of a polysulfone (PSf)/activated carbon (AC) inner layer and a PSf/poly(methyl methacrylate) (PMMA) outer layer, were prepared for co-adsorptive removal of creatinine and urea from aqueous solution. The DLHF membranes were characterized in terms of morphological, physicochemical, water transport, and creatinine adsorption properties. The membrane was then subjected to an ultrafiltration adsorption study for performance evaluation. The incorporation of AC in membrane, as confirmed by microscopic and surface analyses, has improved the pure water flux up to 25.2 L/(m2 h). A membrane with optimum AC loading (9 wt %) demonstrated the highest maximum creatinine adsorption capacity (86.2 mg/g) based on the Langmuir adsorption isotherm model. In the ultrafiltration adsorption experiment, the membrane removed creatinine and urea with a combined average percent removal of 29.3%. Moreover, the membrane exhibited creatinine and urea uptake recoveries of 98.8 and 81.2%, respectively. The combined action of PMMA and AC in the PSf DLHF membrane has made the adsorption of multiple uremic toxins possible during dialysate recovery.
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