Displaying publications 141 - 160 of 364 in total

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  1. Quality of life in Malaysian colorectal cancer patients: a preliminary result
    Natrah MS, Ezat S, Syed MA, Rizal AM, Saperi S
    Asian Pac J Cancer Prev, 2012;13(3):957-62.
    PMID: 22631679
    OBJECTIVE: Rapidly increasing colorectal cancer (CRC) incidence in Malaysia and the introduction of cutting edge new treatments, which prolong survival, mean that treatment outcome measures meed to be evaluated, including consideration of patient's quality of life (QoL) assessment. There are limited data on QoL in CRC patients, especially in Malaysia. Therefore, this study was performed focusing on cancer stages and age groups.

    METHODS: The cross sectional study was conducted from June to September 2011 at three public tertiary hospitals with the EORTC QLQ C-30 questionnaire in addition to face to face interview and review of medical records of 100 respondents.

    RESULTS: The mean age was 57.3 (SD 11.9) years with 56.0% are males and 44.0% females, 62% of Malay ethnicity, 30% Chinese, 7% Indian and 1% Sikh. Majority were educated up to secondary level (42%) and 90% respondents had CRC stages III and IV. Mean global health status (GHS) score was 79.1 (SD 21.4). Mean scores for functional status (physical, emotional, role, cognitive, social) rangeds between 79.5 (SD 26.6) to 92.2 (SD 13.7). Mean symptom scores (fatigue, pain, nausea/vomiting, constipation, diarrhea, insomnia, dyspnoea, loss of appetite) ranged between 4.00 (SD 8.58) to 20.7 (SD 30.6). Respondents role function significantly deteriorates with increasing stage of the disease (p=0.044). Females had worse symptoms of pain (p=0.022), fatigue (p=0.031) and dyspnoea (p=0.031). Mean insomnia (p=0.006) and diarrhea (p=0.024) demonstrated significant differences between age groups.

    CONCLUSION: QOL in CRC patients in this study was comparable to that in other studies done in developed countries. Pain, fatigue and dyspnoea are worse among female CRC patients. Given that functions deteriorates with advanced stage of the disease at diagnosis, a systematic screening programme to detect cases as early as possible is essential nationwide.

  2. Association of Malaysian Helicobacter pylori virulence polymorphisms with severity of gastritis and patients' ethnicity
    Alfizah H, Ramelah M, Rizal AM, Anwar AS, Isa MR
    Helicobacter, 2012 Oct;17(5):340-9.
    PMID: 22967117 DOI: 10.1111/j.1523-5378.2012.00956.x
    Polymorphisms of Helicobacter pylori cagA and vacA genes do exist and may contribute to differences in H. pylori infection and gastroduodenal diseases among races in the Malaysian population. This study was conducted to characterize the polymorphisms in H. pylori cagA and vacA in Malaysian population.
  3. Fulltext Caregivers' satisfaction of healthcare delivery at paediatric clinics of Universiti Kebangsaan Malaysia Medical Centre in 2009
    Aniza I, Rizal AM, Ng YS, Mardhiyyah M, Helmi I, Syamimi BK, et al.
    Med J Malaysia, 2011 Jun;66(2):84-8.
    PMID: 22106682
    Patient's satisfaction has become increasingly important as patients evaluate healthcare services for both medical cost and quality. The purpose of this study was to measure the prevalence and the factors influencing caregivers' satisfaction. A cross sectional study of 262 respondents using universal sampling method was conducted at the paediatric clinics of Universiti Kebangsaan Malaysia Medical Centre (UKMMC). Overall, 90.5% were satisfied with the services provided. Satisfaction rates based on various healthcare delivery domains were: 95.0% for communication skills, 88.5% for interpersonal aspect, 83.6% for technical quality, 82.1% for financial aspect, 72.9% for time spent with doctors and 64.9% for ease of contact. This study shows that the caregivers (an unpaid person who helps a person cope with disease) were highly satisfied with the communicational aspect delivered by the clinic. However, there is still room for improvement on ease of contact domain and waiting time in order to produce high quality service.

    Study site: Paediatric clinic, Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM)
  4. Fulltext Antioxidant intake and status, and oxidative stress in relation to breast cancer risk: a case-control study
    Sharhar S, Normah H, Fatimah A, Fadilah RN, Rohi GA, Amin I, et al.
    Asian Pac J Cancer Prev, 2008 Apr-Jun;9(2):343-49.
    PMID: 18712988
    A case control study was carried out to investigate associations between breast cancer risk, antioxidant status and oxidative stress among women in Klang Valley and Selangor. A total of 57 newly diagnosed cases aged 30 to 66 years old participated and were matched for age and ethnicity with 139 controls with no diagnosis of cancer or other chronic diseases. An interview based questionnaire designed to collect information on demographic and socioeconomic status, as well as reproductive, medical and dietary history was used. Anthropometric measurements including weight, height, waist and hip circumference were made and a 10 ml fasting venous blood sample was taken for glucose testing and analysis of plasma vitamin antioxidants and malondialdehyde. Hair and toenail samples were taken for selenium analysis. Results showed that the mean intake of vitamin A, vitamin E and selenium among cases (606.8 +/- 334.8 microg/d, 6.1 +/- 2.4 g/d, 56.9 +/- 16.2 microg/d) was lower than controls (724.7 +/- 414 microg/day, 6.9 +/- 3.0 g/d, 60.8 +/- 17.5 microg/d, respectively) (p<0.05 for all parameters). A similar trend was noted for plasma vitamin A and E and also selenium in hair and toenails. Poor antioxidant status as indicated by low plasma vitamin A (<284.3 microg/l or <366.3 microg/l) increased risk of breast cancer by approximately two fold, whilst low plasma vitamin E (<2.5 mg/dl, <2.8 mg/dl and <3.1 mg/dl) increased the risk by two to three fold [Adjusted OR 2.97 (95% CI 1.38-3.48), 2.32 (95% CI 1.07-2.41) and 2.12 (95% CI 1.00-4.21)]. Cases had a greater level of malondialdehyde 4.4 +/- 1.1 mmol/g protein), an indicator of oxidative stress, as compared to controls (3.2 +/- 1.7 mmol/g protein) (p<0.05). A high level of MDA (> or = 4.8 mmol/g protein) was associated with breast cancer [Adjusted OR 6.82 (95% CI 1.95-23.9)]. It is concluded that a poor antioxidant status and high oxidative stress are associated with breast cancer risk. Thus, it is essential for Malaysian women to obtain a good antioxidant status by consuming a diet rich in vitamins A and E as well as selenium and adopt healthy behaviour to reduce oxidative stress in order to prevent breast cancer.
  5. Bilateral ophthalmic vein thrombosis secondary to nasal furunculosis
    Rohana AR, Rosli MK, Nik Rizal NY, Shatriah I, Wan Hazabbah WH
    Orbit, 2008;27(3):215-7.
    PMID: 18569833 DOI: 10.1080/01676830802009754
    We were presented with a teenage female who developed superior ophthalmic vein thrombosis and cavernous sinus thrombophlebitis after a 1-week history of a single acne-like lesion or furuncle at the anterior tip of the nose. She was managed aggressively with heparin and intravenous antibiotic. Signs and symptoms improved after 2 weeks of treatment, and she was discharged with an anticoagulant.
  6. Fulltext 1-(2-Hydr-oxy-5-methyl-phen-yl)ethanone [(1H-indol-3--yl)acet-yl]hydrazone
    Ali HM, Zuraini K, Wan Jeffrey B, Rizal MR, Ng SW
    Acta Crystallogr Sect E Struct Rep Online, 2008;64(Pt 5):o912.
    PMID: 21202394 DOI: 10.1107/S1600536808011124
    The indolyl -NH group of the title Schiff base, C(19)H(19)N(3)O(2), forms a hydrogen bond to the -OH group of an inversion-related mol-ecule, resulting in a hydrogen-bonded dimer; adjacent dimers are further linked through an inter-dimer N-H⋯O hydrogen bond involving the -C(=O)-NH-N=fragment to form a linear ribbon that runs along the a axis.
  7. Arterial embolization of a bleeding gastric Dieulafoy lesion: a case report
    Mohd Rizal MY, Kosai NR, Sutton PA, Rozman Z, Razman J, Harunarashid H, et al.
    Clin Ter, 2013;164(1):25-7.
    PMID: 23455738 DOI: 10.7417/T.2013.1506
    Dieulafoy's lesion is one of an unusual cause of upper gastrointestinal bleeding (U GIB). Endoscopic intervention has always been a preferred non-surgical method in treating UGIB including bleeding from Dieulafoy's lesion. Owing to recent advances in angiography, arterial embolization has become a popular alternative in non- variceal UGIB especially in cases with failed endoscopic treatment. However, managing bleeding Dieulafoy's with selective arterial embolization as the first line of treatment has not been exclusively practiced. We hereby, report a case of bleeding Dieulafoy lesion which had been primarily treated with arterial embolization.
  8. Fulltext Most prevalent unmet supportive care needs and quality of life of breast cancer patients in a tertiary hospital in Malaysia
    Edib Z, Kumarasamy V, Binti Abdullah N, Rizal AM, Al-Dubai SA
    Health Qual Life Outcomes, 2016;14:26.
    PMID: 26898558 DOI: 10.1186/s12955-016-0428-4
    Addressing breast cancer patients' unmet supportive care needs in the early stage of their survivorship have become a prime concern because of its significant association with poor quality of life (QOL), which in turn increases healthcare utilization and costs. There is no study about unmet supportive care needs of breast cancer patients in Malaysia. This study aims to assess the most prevalent unmet supportive care needs of Malaysian breast cancer patients and the association between QOL and patients' characteristics, and their unmet supportive care needs.
  9. Fulltext Parasitic infections among aborigine children at Post Brooke, Kelantan, Malaysia
    Rahmah N, Ariff RHT, Abdullah B, Shariman MSM, Nazli MZM, Rizal MZM
    Med J Malaysia, 1997 Dec;52(4):412-5.
    PMID: 10968120
    This study investigated the prevalence of parasitic infections among aborigine children at Post Brooke, Kelantan. Eighty-four formalin-fixed specimens and 78 PVA-fixed specimens were obtained. 79.8% and 35.9% of the samples were positive for helminth ova and protozoa respectively. The parasites detected (single plus mixed infections) were A. lumbricoides (50/84, 59.5%), T. trichiura (35/84, 41.7%), hookworm (5/84, 6.0%), S stercoralis (1/84, 1.2%), G. intestinalis (18/78, 23.1%), E. histolytica (7/78, 9.0%) and E. coli (7/78, 9.0%). Two hundred thick blood film examinations detected only one case of Plasmodium falciparum infection. A high prevalence of intestinal parasitic infections among the children at Post Brooke was demonstrated in this study; thus there is an urgent need to improve the hygiene, education and living standards of this population.
  10. Fulltext Cost analysis of cataract surgery with intraocular lens implantation: a single blind randomised clinical trial comparing extracapsular cataract extraction and phacoemulsification
    Rizal AM, Aljunid SM, Normalina M, Hanom AF, Chuah KL, Suzainah Y, et al.
    Med J Malaysia, 2003 Aug;58(3):380-6.
    PMID: 14750378
    A randomised single blinded clinical trial to compare the cost of cataract surgery between extracapsular cataract extraction (ECCE) and phacoemulsification (PEA) was conducted at Hospital Universiti Kebangsaan Malaysia (HUKM) between March and December 2000. A total of 60 patients were included in this study. The cost of a cataract surgery incurred by hospital, patients and households up to two months after discharge were included. The costs of training, loss of patients' income after discharge and intangible costs were excluded. Results showed that the average cost for one ECCE operation is RM1,664.46 (RM1,233.04-RM2,377.64) and for PEA is RM1,978.00 (RM1,557.87-RM3,334.50). During this short period of follow up, it can be concluded that ECCE is significantly cheaper than PEA by an average difference of RM 313.54 per patient (p < 0.001). Cost of equipment and low frequency of PEA technique done in HUKM were the two main reasons for the high unit cost of PEA as compared to ECCE.
  11. Fulltext Numerical study of tides in the Malacca Strait with a 3-D model
    Haditiar Y, Putri MR, Ismail N, Muchlisin ZA, Ikhwan M, Rizal S
    Heliyon, 2020 Sep;6(9):e04828.
    PMID: 32939416 DOI: 10.1016/j.heliyon.2020.e04828
    Malacca Strait (MS) has an important role and potential for many countries. It is a major transportation route for oil and commodities across continents. In addition, various activities such as shipping, fishing, aquaculture, oil drilling, and energy are also carried out in MS. Tides strongly affect the MS environment so that it becomes a major parameter in MS management. This paper is the first study, which presents MS tidal hydrodynamics based on a baroclinic and nonhydrostatic approach. Tidal hydrodynamics in MS and the surrounding waters were assessed using tidal forces, temperature, salinity, and density. This study analyzes the amplitude, phase, current ellipses, and semi-major axis of the tides. These variables are obtained from the simulation results of the three-dimensional numerical models of M2 tides and combined tides (M2, S2, N2, K1, and O1) with nonhydrostatic models. Then the results obtained are verified by observation data. Amplitude and phase of the tidal wave in MS originate from two directions, namely the northern part of MS (Andaman Sea) and the South China Sea (SCS). Tides from the north of MS propagate into the MS, while tides from the SCS travel to Singapore Waters (SW) and the south of MS. This causes a complex residual flow in SW and shoaling in the middle of MS. Shoaling in the middle of MS is characterized by a large amplitude and semi-major, as in B. Siapiapi. The results of this analysis show that tidal waves are dominated by semidiurnal types rather than diurnal types. The M2 current ellipse has dominantly anticlockwise rotation along the west of the MS, while along the east of MS, it has generally a clockwise rotation.
  12. Fulltext Combination of Superheated Steam with Laccase Pretreatment Together with Size Reduction to Enhance Enzymatic Hydrolysis of Oil Palm Biomass
    Ahmad Rizal NFA, Ibrahim MF, Zakaria MR, Kamal Bahrin E, Abd-Aziz S, Hassan MA
    Molecules, 2018 Apr 02;23(4).
    PMID: 29614823 DOI: 10.3390/molecules23040811
    The combination of superheated steam (SHS) with ligninolytic enzyme laccase pretreatment together with size reduction was conducted in order to enhance the enzymatic hydrolysis of oil palm biomass into glucose. The oil palm empty fruit bunch (OPEFB) and oil palm mesocarp fiber (OPMF) were pretreated with SHS and ground using a hammer mill to sizes of 2, 1, 0.5 and 0.25 mm before pretreatment using laccase to remove lignin. This study showed that reduction of size from raw to 0.25 mm plays important role in lignin degradation by laccase that removed 38.7% and 39.6% of the lignin from OPEFB and OPMF, respectively. The subsequent saccharification process of these pretreated OPEFB and OPMF generates glucose yields of 71.5% and 63.0%, which represent a 4.6 and 4.8-fold increase, respectively, as compared to untreated samples. This study showed that the combination of SHS with laccase pretreatment together with size reduction could enhance the glucose yield.
  13. Fulltext Evaluation of Interfacial Fracture Toughness and Interfacial Shear Strength of Typha Spp. Fiber/Polymer Composite by Double Shear Test Method
    Ikramullah, Rizal S, Nakai Y, Shiozawa D, Khalil HPSA, Huzni S, et al.
    Materials (Basel), 2019 Jul 10;12(14).
    PMID: 31295885 DOI: 10.3390/ma12142225
    The aim of this paper is to evaluate the Mode II interfacial fracture toughness and interfacial shear strength of Typha spp. fiber/PLLA and Typha spp. fiber/epoxy composite by using a double shear stress method with 3 fibers model composite. The surface condition of the fiber and crack propagation at the interface between the fiber and the matrix are observed by scanning electron microscope (SEM). Alkali treatment on Typha spp. fiber can make the fiber surface coarser, thus increasing the value of interfacial fracture toughness and interfacial shear strength. Typha spp. fiber/epoxy has a higher interfacial fracture value than that of Typha spp. fiber/PLLA. Interfacial fracture toughness on Typha spp. fiber/PLLA and Typha spp. fiber/epoxy composite model specimens were influenced by the matrix length, fiber spacing, fiber diameter and bonding area. Furthermore, the interfacial fracture toughness and the interfacial fracture shear stress of the composite model increased with the increasing duration of the surface treatment.
  14. Fulltext Interfacial Compatibility Evaluation on the Fiber Treatment in the Typha Fiber Reinforced Epoxy Composites and Their Effect on the Chemical and Mechanical Properties
    Rizal S, Ikramullah, Gopakumar DA, Thalib S, Huzni S, Abdul Khalil HPS
    Polymers (Basel), 2018 Nov 28;10(12).
    PMID: 30961241 DOI: 10.3390/polym10121316
    Natural fiber composites have been widely used for various applications such as automotive components, aircraft components and sports equipment. Among the natural fibers Typha spp have gained considerable attention to replace synthetic fibers due to their unique nature. The untreated and alkali-treated fibers treated in different durations were dried under the sun for 4 h prior to the fabrication of Typha fiber reinforced epoxy composites. The chemical structure and crystallinity index of composites were examined via FT-IR and XRD respectively. The tensile, flexural and impact tests were conducted to investigate the effect of the alkali treated Typha fibers on the epoxy composite. From the microscopy analysis, it was observed that the fracture mechanism of the composite was due to the fiber and matrix debonding, fiber pull out from the matrix, and fiber damage. The tensile, flexural and impact strength of the Typha fiber reinforced epoxy composite were increased after 5% alkaline immersion compared to untreated Typha fiber composite. From these results, it can be concluded that the alkali treatment on Typha fiber could improve the interfacial compatibility between epoxy resin and Typha fiber, which resulted in the better mechanical properties and made the composite more hydrophobic. So far there is no comprehensive report about Typha fiber reinforcing epoxy composite, investigating the effect of the alkali treatment duration on the interfacial compatibility, and their effect on chemical and mechanical of Typha fiber reinforced composite, which plays a vital role to provide the overall mechanical performance to the composite.
  15. Isolated blunt iliac artery injury successfully treated with endovascular stent
    Lee EP, Huei TJ, Lip Henry TC, Salinawati B, Yuzaidi M, Rizal IA
    Chin J Traumatol, 2021 Aug 21.
    PMID: 34503906 DOI: 10.1016/j.cjtee.2021.08.010
    Common or external iliac artery injury due to blunt trauma is unusual without an associated pelvic fracture. Here we report on a 62 years old man that sustained left external iliac artery thrombosis due to blunt trauma following fall from motorbike. There was no immediate circulatory compromise. Contrasted CT of abdomen revealed an associated left lower abdominal wall traumatic hernia. The iliac artery was intervened with an endovascular stent to restore luminal flow and the hernia was repaired electively. The entire clinical course and management dilemma are described in this article.
  16. Fulltext The Effect of Brain Breaks on Physical Activity Behaviour among Primary School Children: A Transtheoretical Perspective
    Rizal H, Hajar MS, Muhamad AS, Kueh YC, Kuan G
    Int J Environ Res Public Health, 2019 11 04;16(21).
    PMID: 31690004 DOI: 10.3390/ijerph16214283
    Brain Breaks Physical Activity Solutions (BBPAS) is a web-based structured physical activity (PA) video that is specifically designed for school settings and can stimulate a student's health and learning. The purpose of this study is to measure the effect of BBPAS on the stages of change, decisional balance, processes of change, self-efficacy and leisure-time exercise among Malay ethnic primary school children. A validated Malay version of three of the five constructs was derived with sound validity and was used in the present study. A total of 159 male and 163 female children aged 10 to 11 years old, mean (SD) = 10.53 (0.50), were recruited from two schools in Kelantan, Malaysia. Purposive sampling was used to divide the children into intervention (n = 177) and control (n = 145) groups. Children in the intervention group underwent BBPAS activity for an accumulated 30 min per week, while children in the control group were not involved in the BBPAS intervention. Mixed factorial analysis of variance (ANOVA) was used to examine the effect of BBPAS on the study variables. A mixed ANOVA showed significant changes (time effect) on cognitive process, F(1, 320) = 5.768, p-value = 0.017; behavioural process, F(1, 313) = 5.736, p-value = 0.017; and internal feeling, F(1, 312) = 6.050, p-value = 0.014. There was also a significant difference between groups on cons, F(1, 316) = 7.504, p-value = 0.007. A significant interaction effect was observed for stages of change, F(1, 319) = 7.861, p-value = 0.005; pros, F(1, 316) = 31.311, p-value = 0.001; internal feeling, F(1, 312) = 4.692, p-value = 0.031; and behavioural process, F(1, 313) = 7.312, p-value = 0.007. In conclusion, BBPAS was successful in improving four of the five constructs, and thus, should be recommended to be used in schools throughout Malaysia.
  17. Bright sports, physical activity investments that work: implementing brain breaks in Malaysian primary schools
    Kuan G, Rizal H, Hajar MS, Chin MK, Mok MMC
    Br J Sports Med, 2019 Feb 21.
    PMID: 30792256 DOI: 10.1136/bjsports-2018-100146
  18. Fulltext The role of silica-containing agro-industrial waste as reinforcement on physicochemical and thermal properties of polymer composites
    Rizal S, Fizree HM, Hossain MS, Ikramullah, Gopakumar DA, Wan Ni EC, et al.
    Heliyon, 2020 Mar;6(3):e03550.
    PMID: 32190763 DOI: 10.1016/j.heliyon.2020.e03550
    This study was conducted to determine the influence of the oil palm boiler ash (OPBA) reinforcement on the microstructural, physical, mechanical and thermal properties of epoxy polymer composites. The chemical composition analysis of OPBA revealed that it contains about 55 wt.% of SiO2 along with other metallic oxides and elements. The surface morphology of OPBA showed angular and irregular shapes with porous structures. The influence of OPBA as a reinforcement in epoxy composite was studied with varying filler loadings (10-50 wt.%) and different particle sizes (50-150 μm). The result showed that the incorporation of OPBA in composites has improved the physical, mechanical and thermal properties of the epoxy matrix. The highest physical and mechanical properties of fabricated composites were attained with 30 wt.% loading and size of 50 μm. Also, thermal stability and the percentage of char residue of the composite increased with increasing filler loading. Furthermore, the contact angle of OPBA reinforced epoxy composites increased with the increase of filler loading. The lowest value of the contact angle was obtained at 30 wt.% of filler loading with the OPBA particle size of 50 μm. The finding of this study reveals that the OPBA has the potential to be used as reinforcement or filler as well as an alternative of silica-based inorganic fillers used in the enhancement of mechanical, physical and thermal properties of the epoxy polymer composite.
  19. Factors associated with control of type I diabetes in Malaysian adolescents and young adults
    Tan SM, Shafiee Z, Wu LL, Rizal AM, Rey JM
    Int J Psychiatry Med, 2005;35(2):123-36.
    PMID: 16240970 DOI: 10.2190/EQ71-RMWV-6CEJ-1DGM
    Objectives: To examine the association between ethnicity, depression, quality of life, and diabetic control in Malaysian adolescents and young adults with type I diabetes mellitus.

    Methods: Fifty-two outpatients with type I diabetes (mean age 15.5 years) who attended a Diabetes Clinic were included. The level of HbA1c was the measure of diabetes control used (better control defined as HbA1c < 10%). Other variables were measured through questionnaires (e.g., depressive symptoms, quality of life), computerized diagnostic interviews (major depression), and medical records (e.g., demographic, family circumstances, compliance with treatment).

    Results: Ethnic Chinese youth showed better diabetic control than Malays and Indians (mean HbA1c 9.1%, 10.3%, and 11.0% respectively). Young people with better diabetic control (HbA1c < 10%) were more likely to have better quality of life and less likely to live in problematic families. When the cut-off for diabetic control was stricter (HbA1c < or = 8%), the young person's compliance was the main predictor of poor control. Family problems were also associated with poor control but to a lesser extent. The initial association between poorer diabetes control and depression became non-significant when quality of life was taken into account.

    Conclusions: There are ethnic differences in juvenile diabetic control in this Malaysian sample which need to be understood further. Previous findings of an association between quality of life and glycemic control were verified but different definitions of good control showed different associations with individual and environmental variables. Clinicians' awareness and early intervention for psychosocial problems (for example, inadequate family support) could improve diabetes control.
  20. Fulltext Health-related quality of life of younger and older lower-income households in Malaysia
    Rizal H, Said MA, Abdul Majid H, Su TT, Maw Pin T, Ismail R, et al.
    PLoS One, 2022;17(2):e0263751.
    PMID: 35134086 DOI: 10.1371/journal.pone.0263751
    BACKGROUND: Globally, a lower income is associated with poorer health status and reduced quality of life (QOL). However, more research is needed on how being older may influence QOL in lower-income households, particularly as older age is associated with an increased risk of chronic diseases and care needs. To this end, the current study attempts to determine the health-related QOL (HRQOL) among individuals from lower-income households aged 60 years and over compared to lower-income adults aged less than 60 years.

    METHODS: Participants were identified from the Department of Statistics Malaysia sampling frame. Surveys were carried out with individual households aged 18 years and older through self-administered questionnaires. Information was collected on demographics, household income, employment status, number of diseases, and HRQOL assessed using the EuroQol 5-Dimension 5-Level (EQ-5D-5L) tool.

    RESULTS: Out of a total of 1899 participants, 620 (32.6%) were female and 328 (17.3%) were aged 60 years and above. The mean (SD) age was 45.2 (14.1) and mean (SD) household income was RM2124 (1356). Compared with younger individuals, older respondents were more likely to experience difficulties in mobility (32.1% vs 9.7%, p<0.001), self-care (11.6% vs 3.8%, p<0.001), usual activities (24.5% vs 9.1%, p<0.001), pain/discomfort (38.8% vs 16.5%, p<0.001) and anxiety/depression (21.4% vs 13.5%, p<0.001). The mean (SD) EQ-5D index scores were lower among older respondents, 0.89 (0.16) vs 0.95 (0.13), p = 0.001. After adjusting for covariates, age was a significant influencing factor (p = 0.001) for mobility (OR = 2.038, 95% CI:1.439-2.885), usual activities (OR = 1.957, 95% CI:1.353-2.832) and pain or discomfort (OR = 2.241, 95% CI:1.690-2.972).

    CONCLUSION: Lower-income older adults had poorer HRQOL compared to their younger counterparts. This has important implications concerning intervention strategies that incorporate active ageing concepts on an individual and policy-making level to enhance the QOL and wellbeing, particularly among the older lower-income population.

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