Displaying publications 1 - 20 of 340 in total

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  1. Figueroa A
    Zootaxa, 2021 Jun 01;4980(2):397400.
    PMID: 34186971 DOI: 10.11646/zootaxa.4980.2.12
    The agamid genus Bronchocela Kaup, 1827 comprises 13 species of diurnal, arboreal lizards distributed from India east through Myanmar, Thailand, Cambodia, Vietnam, Malaysia, Singapore, Indonesia, the Philippines, to Papua New Guinea (Diong Lim 1998; Hallermann 2005; Grismer et al. 2015). Once occupying this entire range, B. cristatella's distribution has now been restricted to the Andaman and Nicobar Islands, southern Thailand, Malaysia, Singapore, Indonesia, the Philippines, and Papua New Guinea (Hallermann 2005). My intention here is to: 1) clarify the type species of the genus-group name Bronchocela; 2) resolve the valid name for the taxon under consideration; 3) designate lectotypes for Agama cristatella Kuhl, 1820 and Agama gutturosa Merrem, 1820, and; 4) discuss the type locality for the taxon under consideration.
  2. Rossi W, Weir A
    Mycologia, 2007 8 1;99(1):139-43.
    PMID: 17663133
    Four new species of Stigmatomyces (Ascomycetes, Laboulbeniales, Stigmatomycetinae) parasitic on flies (Diptera) are described. These are S. benjaminii, parasitic on Spilochroa polita (Trixoscelididae) from Mexico, S. munarii, parasitic on Trixoscelis namibensis (Trixoscelididae) from Namibia, S. neurochaetae parasitic on Neurochaeta parviceps (Neurochaetidae) from Malaysia, and S. zaleae, parasitic on Zalea spp. (Tethinidae) from Australia. Both Trixoscelididae and Neurochaetidae are new host families for Laboulbeniales.
  3. Khoo ACH
    Indian J Nucl Med, 2018 4 13;33(2):165-166.
    PMID: 29643684 DOI: 10.4103/ijnm.IJNM_148_17
    An 89-year-old man undergoing fluorine-18 fluorodeoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) study posttherapy for hepatocellular carcinoma was noted to have 18F-FDG posterior layering of the urinary bladder. This phenomenon of posterior layering of 18F-FDG in the urinary bladder during PET/CT studies is physiological, and it is important to recognize to avoid misinterpretation and unnecessary investigations. The hypotheses for the cause of this phenomenon are highlighted in these interesting images including the reversed phenomenon where there is anterior layering of 18F-FDG.
  4. Natarajan R, Eapen A, Jambulingam P
    Zootaxa, 2020 Jan 16;4722(5):zootaxa.4722.5.5.
    PMID: 32230607 DOI: 10.11646/zootaxa.4722.5.5
    The original description of Heizmannia (Heizmannia) metallica (Leicester) from Malaysia, and specimens collected in India that were provisionally identified as Hz. metallica, were re-examined for their taxonomic status. Heizmannia metallica from Malaysia was found by Mattingly (1970) to be a junior synonym of Hz. indica (Theobald), whereas we found the specimens identified as Hz. metallica from India to differ distinctly from the holotype of Hz. metallica. We collected adults near Malabar Coast, Western Ghats which corresponded with Indian Hz. metallica sensu auctorum and here describe the previously misidentified species as Hz. (Hez.) rajagopalani n. sp. The adult male and female of the new species, and their genitalia, are described and illustrated.
  5. Alex D, Fauzi AB, Mohan D
    Front Public Health, 2020;8:612154.
    PMID: 33520920 DOI: 10.3389/fpubh.2020.612154
    Introduction: With a rapidly aging population, the Malaysian health care system needs to develop solutions to address the lack of resources that are required for the assessment of the older person. The complex nature of geriatric syndromes coupled with the occurrence of multiple comorbid illnesses with aging, make geriatric assessment a resource intensive process. Digital health solutions could play an important role in supporting existing health care systems, especially in low and middle income countries, with limited speciality services in geriatrics. Objective: This is a pilot study aimed at screening for geriatric syndromes through self-administered online surveys in urban community dwelling older Malaysians and assessing the pattern of geriatric syndromes in relation to the frailty status of the study participants. Methods: This is a cross-sectional pilot study conducted between July-September 2020. Community dwelling adults aged 60 years and over were invited to take part in an online survey. Information on sociodemographic variables, comorbidities, and the self-reported results of geriatric syndromes (frailty, sarcopenia, anorexia of aging, urinary incontinence, falls, and cognitive impairment), were collected through the survey. Results: Data was collected for 162 participants over a period of 2 months. The mean (SD) age of the respondents was 66.42 (5.25) years with 64.9% females. Majority of the respondents were of Chinese ethnic origin (67.9%) and had tertiary level of education (75.9%). The average time taken by participants to complete the survey was 16.86 min. Urinary incontinence was the highest reported geriatric syndrome (55.1%) followed by falls (37.6%), anorexia of aging (32.8%), cognitive impairment (27.8%), and sarcopenia (8.3%). Frailty was detected in 4.5% of the study population. Loss of weight in the previous year was the highest reported component of the frailty assessment tool. The presence of sarcopenia, anorexia of aging, poor/fair self-rated health, urinary incontinence, and multimorbidity were significantly higher in older adults who were frail or prefrail. Conclusion: Screening for geriatric syndromes through online surveys is a feasible approach to identify older adults in the community who are likely to benefit from geriatric assessment. However, the demographic profile of the older population that are accessible through such digital platforms is limited.
  6. Alex Zhen Kai Lo, Siti Khadijah Lukman, Syafiqah Saidin
    MyJurnal
    Introduction: : Ginseng is a type of traditional medicine that has been used for thousand years to treat various dis- eases and has been proven effective in treating cardiovascular diseases. Incorporation of polyaniline (PANI) which is a type of conductive polymer together with ginseng into poly(lactic-co-glycolic acid) (PLGA) microcapsules is neces- sary for the treatment of cardiovascular diseases as the polymer will control drug release and the electroconductivity of PANI is beneficial on myocardium cells. Methods: Therefore, this project involved the encapsulation of ginseng inside PLGA/PANI microcapsules. The encapsulation of ginseng inside the microcapsules was verified through the identification of chemical composition of ginseng, PLGA and PANI using attenuated total reflectance-Fourier trans- form infrared spectroscopy (ATR-FTIR). Results: The results of scanning electron microscope (SEM) showed the formation of microspheres where the microcapsule size was decreased from 3.14±1.87 μm to 1.98±1.30 μm as the concentration of PANI increased. The distribution of microcapsules size was more homogeneous in the high con- centration of PANI as been determined through the histogram analysis. In addition, the fluorescence analysis demon- strated the efficiency of ginseng encapsulation inside PLGA/PANI microcapsules through the appearance of stained ginseng inside the microcapsules. Conclusion: As a conclusion, the ginseng was successfully encapsulated within PLGA/PANI microcapsules that will be beneficial in drug delivery application, specifically in the cardiovascular area.
  7. Ravi Kumar, P., Alex Goh, K.L., Ashutosh, K.S.
    MyJurnal
    Link analysis algorithms for Web search engines determine the importance and relevance of Web pages. Among the link analysis algorithms, PageRank is the state of the art ranking mechanism that is used in Google search engine today. The PageRank algorithm is modeled as the behavior of a randomized Web surfer; this model can be seen as Markov chain to predict the behavior of a system that travels from one state to another state considering only the current condition. However, this model has the dangling node or hanging node problem because these nodes cannot be presented in a Markov chain model. This paper focuses on the application of Markov chain on PageRank algorithm and discussed a few methods to handle the dangling node problem. The Experiment is done running on WEBSPAM-UK2007 to show the rank results of the dangling nodes.
  8. Khoo ACH, Yeoh KW
    Clin Nucl Med, 2019 Oct;44(10):808-809.
    PMID: 31348083 DOI: 10.1097/RLU.0000000000002739
    Extramammary Paget's disease (EMPD) is a rare disease with an estimated prevalence of 0.1 to 2.4 per 1,000,000 person-years. Metastatic EMPD has a poor prognosis with a 5-year survival of approximately 7%. Local therapy is the only curative option with surgery being recommended for resectable disease. It is therefore crucial to be able to stage such patients appropriately. The utility of F-FDG PET/CT for this disease is not well established. We share a case on how F-FDG PET/CT was used to stage metastatic EMPD.
  9. Khoo ACH, Chen SL
    World J Nucl Med, 2019 9 14;18(3):301-303.
    PMID: 31516376 DOI: 10.4103/wjnm.WJNM_43_18
    Follicular thyroid cancers are known to spread hematogenously to the bones and lungs and rarely presenting with massive angioinvasion. We report a case of a middle-aged female who had undergone total thyroidectomy for minimally invasive follicular thyroid cancer with angioinvasion in 2014. She was noted to have a large tumor thrombus extending from the superior vena cava to the right atrium on whole body scan post-Iodine-131 (131I) remnant ablation therapy. We discuss the various imaging modalities, treatment options, and difficulties in managing such massive angioinvasion in patients with well-differentiated thyroid cancers.
  10. Khoo ACH, Cheong YT
    World J Nucl Med, 2020 01 14;19(1):89-91.
    PMID: 32190033 DOI: 10.4103/wjnm.WJNM_14_19
    Renal cell carcinomas (RCCs) commonly metastasize to the lungs and bones and rarely to the parathyroid, maxillary sinus, and adrenals. It is indeed very rare to have these all these metastases occurring simultaneously in an individual. We share a case of 67-year-old woman provisionally treated for parathyroid carcinoma but subsequently found to actually have metastatic RCC to the left maxillary sinus, parathyroid, lungs, and adrenals on 18F-fluorodeoxyglucose positron emission tomography-computed tomography.
  11. Khoo ACH, Chew GK
    Indian J Nucl Med, 2019 5 2;34(2):162-163.
    PMID: 31040534 DOI: 10.4103/ijnm.IJNM_27_19
    Endometriosis is commonly associated with chronic pelvic pain and its presentation varies between individuals. The only way to confirm the presence of endometriosis is via keyhole or open surgery. In the presence of hematuria, deep endometriotic infiltration needs to be considered. We share an interesting case highlighting the role of 18F-fluorodeoxyglucose positron emission tomography-computed tomography in evaluating a posterior urinary bladder wall lesion and hypodense liver lesions in a middle-aged woman with presenting with frank hematuria in the background of treated cervical intraepithelial neoplasia and adenomyosis.
  12. Figueroa A, Low MEY
    Zootaxa, 2021 Apr 01;4951(1):zootaxa.4951.1.10.
    PMID: 33903421 DOI: 10.11646/zootaxa.4951.1.10
    The snake genus Cylindrophis Wagler, 1828 belongs to the  monogeneric family Cylindrophiidae comprising 15 species distributed predominately throughout SE Asia, with one extralimital species occurring in Sri Lanka (Bernstein et al. 2020: 535). Cylindrophis lineatus is a rare species known from only eight museum specimens (discussed herein), and a photograph of one live individual from Kuching, Sarawak, East Malaysia (Stuebing et al. 2014: 63). Despite being originally described with Singapore as the type-locality (Blanford 1881: 217, 218), it is currently understood that C. lineatus is endemic to western Sarawak, East Malaysia (Stuebing et al. 2014: 63). Wallach et al. (2014: 204) stated that C. lineatus is also found in Kalimantan, but did not provide any references. This appears to have been followed by Bernstein et al. (2020: 537), who provide a map indicating C. lineatus occurrences in Kalimantan. The original description of Cylindrophis lineatus is conventionally cited as Blanford (1881: 217, 218, pl. 20). Herein, we demonstrate that the authorship and date of publication of this taxon should correctly be Cylindrophis lineatus Dennys, 1880b, and discuss that the type locality should be changed to "Borneo".
  13. He AJ, Tang VFY
    Health Policy, 2021 03;125(3):351-362.
    PMID: 33422336 DOI: 10.1016/j.healthpol.2020.12.020
    Against the backdrop of rapid ageing populations, there is an increasing recognition of the need to integrate various health services for the elderly, not only to provide more coordinated care, but also to contain the rapid cost inflation driven primarily by the curative sector. Funded by the Asia-Pacific Observatory on Health Systems and Policies, this scoping review seeks to synthesize the received knowledge on care integration for the elderly in four Asian societies representing varying socioeconomic and health-system characteristics: Singapore, Hong Kong, Malaysia, and Indonesia. The search for English-language literature published between 2009 and 2019 yielded 67 publications in the final sample. The review finds that both research and practice regarding health service integration are at a preliminary stage of development. It notes a marked trend in seeking to integrate long-term elderly care with curative and preventive care, especially in community settings. Many distinctive models proliferated. Integration is demonstrated not only horizontally but also vertically, transcending public-private boundaries. The central role of primary care is highly prominent in almost all the integration models. However, these models are associated with a variety of drawbacks in relation to capacity, perception, and operation that necessitate further scholarly and policy scrutiny, indicating the robustness and persistence of siloed healthcare practices.
  14. Khoo ACH, Tang WH
    Clin Nucl Med, 2019 Oct 23.
    PMID: 31693604 DOI: 10.1097/RLU.0000000000002797
    Urothelial carcinoma is the fourth most common genitourinary tumor with the majority of the tumor involving the urinary bladder. Only 5% involves the renal pelvis and ureter. Metastatic urothelial carcinoma of the renal pelvis frequently involves the lymph nodes, lung, liver, bone, and peritoneum. We share rare interesting F-FDG PET/CT images of a 60-year-old man with metastatic urothelial carcinoma of the renal pelvis to the bowel.
  15. Khoo ACH, Lee YF
    Nucl Med Mol Imaging, 2019 02;53(1):71.
    PMID: 30828404 DOI: 10.1007/s13139-018-0557-2
    [This corrects the article DOI: 10.1007/s13139-016-0395-z.].
  16. Khoo ACH, Lim SY
    World J Nucl Med, 2021 08 20;20(3):322-323.
    PMID: 34703405 DOI: 10.4103/wjnm.wjnm_8_21
    Leiomyomatosis peritonealis disseminata (LPD) is a rare benign condition characterized by multiple smooth muscle implants in the peritoneal cavity. The clinical presentation is usually nonspecific abdominal discomfort and nontender abdominal mass. Preoperative imaging usually points to suggests malignancy due to its unusual location, but the diagnosis can only be confirmed by histopathological examination. We share 18F-Fluorodeoxyglucose positron emission tomography-computed tomography images of a 43-year-old woman diagnosed with LPD and briefly discuss the clinical aspects of this disease.
  17. Khoo ACH, Lee YF
    Nucl Med Mol Imaging, 2017 06;51(2):195-196.
    PMID: 28559948 DOI: 10.1007/s13139-016-0395-z
    Tenofovir, used in the treatment of chronic hepatitis B and HIV, is known for its side effects on the kidneys and bones. We share interesting images of a patient with tenofovir-induced osteomalacia on Technetium-99 m hydroxymethyelene (Tc-99 m HDP) bone scintigraphy. Pattern recognition of this bone scintigraphy and correlation with the clinical history is essential to avoid misdiagnosis.
  18. Loh MA, Alex Khoo PC, Chong MF
    Med J Malaysia, 2016 04;71(2):79-80.
    PMID: 27326949
    Neuromyelitis optica (NMO) is a rare disorder in children with variable presentation. We report a 7-year-old boy who presented with bilateral retrobulbar optic neuritis and responded very well to treatment. He was also positive for aquaporin 4 (AQP4) antibodies, which is part of an emerging endophenotype within autoimmune neurological disorders in childhood.
  19. Alex Kim RJ, Chin ZH, Sharlyn P, Priscilla B, Josephine S
    Med J Malaysia, 2019 Oct;74(5):385-388.
    PMID: 31649213
    INTRODUCTION: Patient safety is defined as 'the prevention of harm caused by errors of commission and omission'. Patient safety culture is one of the important determining factor in safety and quality in healthcare. The purpose of this study is to assess the views and perceptions of health care professionals about patient safety culture in Sarawak General Hospital (SGH).

    METHODS: A cross-sectional study, using the 'Hospital Survey on Patient Safety Culture (HSOPSC)' questionnaire was carried out in 2018 in SGH. Random sampling was used to select a wide range of staff in SGH. A self-administered questionnaire was distributed to 500 hospital staff consisting of doctors, nurses, pharmacist and other clinical and non-clinical staff, conducted from March to April 2018. A total of 407 respondents successfully completed the questionnaire. Therefore, the final response rate for the survey was 81.4%. This study used SPSS 22.0 for Windows and Hospital Data Entry and Analysis Tool that works with Microsoft Excel developed by United States Agency for Healthcare Research and Quality (AHRQ) to perform statistical analysis on the survey data.

    RESULTS: Majority of the respondents graded the overall patient safety as acceptable (63.1%) while only 3.4% graded as excellent. The overall patient safety score was 50.1% and most of the scores related to dimensions were lower than the benchmark scores (64.8%). Generally, the mean positive response rate for all the dimensions were lower than composite data of AHRQ, except for "Organizational Learning - Continuous Improvement", which is also the highest positive response rate (80%), higher than AHRQ data (73%). The result showed that SGH has a good opportunity to improve over time as it gains experience and accumulates knowledge. On the other hand, the lowest percentage of positive responses was "Non-punitive response to error" (18%), meaning that most of the staff perceived that they will be punished for medical error.

    CONCLUSIONS: The level of patient safety culture in SGH is acceptable and most of the scores related to dimensions were lower than benchmark score. SGH as a learning organisation should also address the issues of staffing, improving handoff and transition and develop a non-punitive culture in response to error.

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