MyMedR

Fulltext Prevalence and factors associated with low back pain among tea plantation workers in Cameron Highlands, Malaysia

Abdul Hadi H

Journal of Occupational Safety and Health, 2016;13(1):1-10.

MyJurnal

A cross sectional study was conducted among tea plantation workers in Cameron Highlands from July to December 2006 to study the prevalence of low back pain and factors associated with it. One hundred and six tea plantation field workers participated in the study. Data was collected using self-administered questionnaire. Time motion studies were also conducted for 3 different job categories. The prevalence of back pain experienced throughout their work in the plantation was 81.1% and the prevalence of low
back pain experienced in the past 12 months was 64.2%. Feeling the need to work as fast as possible was a significant predictor of low back pain and increased the risk by 3.5 times, therefore it is suggested that both the management and workers give serious attention to this particular aspect to reduce the incidence of low back pain.

The post-mortem resilience of facial creases and the possibility for use in identification of the dead

Hadi H, Wilkinson CM

Forensic Sci Int, 2014 Apr;237:149.e1-149.e7.

PMID: 24613011 DOI: 10.1016/j.forsciint.2013.12.014

The post-mortem resilience of facial creases was studied using donated bodies in order to establish the efficacy of crease analysis for identification of the dead. Creases were studied on normal (pre-embalmed) and bloated (embalmed) cadavers at the Centre for Anatomy and Human Identification (CAHID) to establish whether facial bloating would affect facial crease visibility. Embalming was chosen to simulate the effects produced by post-mortem bloating. The results suggested that creases are resilient and changes were only detected for creases located on the periphery of the face, particularly at areas where the skin is thick, such as at the cheeks. Two new creases not previously classified were identified; these creases were called the vertical superciliary arch line and the lateral nose crease. This research suggests that facial creases may be resilient enough after death to be utilised for human identification.

The biodiversity of black flies (Diptera: Simuliidae) in Indonesia

Hadi UK, Takaoka H

Acta Trop, 2018 Sep;185:133-137.

PMID: 29452114 DOI: 10.1016/j.actatropica.2018.02.013

Indonesia is one of the megadiversity country in the world endowed with rich and unique biodiversity insects such as blackflies species (Diptera: Simuliidae). Blackflies are found almost anywhere with running water suitable as habitat for the immature stages. This family is one of the most important groups of blood-sucking insects. This study collates the records of Simulium (Diptera: Simuliidae) in previous publications related fauna of Indonesia. Based on the results of this study, there were 124 species of blackflies in Indonesian Archipelago. All species are assigned to the genus Simulium Latreille s.l., and are placed into five subgenera, i.e. Gomphostilbia Enderlein, Morops Enderlein, Nevermannia Enderlein, Simulium Latreille s.str. and Wallacellum Takaoka. Further classification into 27 species groups within the subgenera were also made. Checklists of Indonesian Simuliidae are provided including data on the distribution of each species.

Categorizing facial creases: A review

Hadi H, Wilkinson CM

J Cosmet Dermatol, 2017 Jun;16(2):180-185.

PMID: 28145033 DOI: 10.1111/jocd.12305

Ensuring uniformity in the nomenclature standardization of facial creases is important to enable the scholarly community to follow and debate the advancements in research. This review highlights the prevailing disparity in the nomenclature that refers to the same facial crease by researchers and laypeople, and suggests uniform names for the facial creases based on available literature. The previous and current trends in facial crease classification are also discussed. The nomenclature of the facial creases considered for this review include the following: the nasolabial fold, corner of the mouth lines, upper and lower lip creases around the mouth region, the mandibular folds, the bifid nose, the transverse nasal line, the vertical glabellar line, chin crease, the mental crease, four type of creases around the eyes, forehead creases, and periauricular creases. A figure illustrating the above facial creases is included as reference. It is hoped that the proposed standardization of nomenclature would ensure a more scientific referencing of facial creases enabling more effective scientific interaction among the scholarly community as well as the laypeople interested in the research and application of facial creases.

Fulltext Impact of pharmacist recruitment on ADR reporting: Malaysian experience

Hadi MA, Ming LC

South Med Rev, 2011 Dec;4(2):102-3.

PMID: 23093890 DOI: 10.5655/smr.v4i2.1009

Fulltext Boronate derivatives of functionally diverse catechols: stability studies

Ketuly KA, Hadi AH

Molecules, 2010 Apr;15(4):2347-56.

PMID: 20428047 DOI: 10.3390/molecules15042347

Benzeneboronate of catecholic carboxyl methyl esters, N-acetyldopamine, coumarin and catechol estrogens were prepared as crystalline derivatives in high yield. Related catechol compounds with extra polar functional group(s) (OH, NH2) do not form or only partially form unstable cyclic boronate derivatives.

Neuromuscular blocking activity of a glycosidic extract of the plant Sarcolobus globosus

Mustafa MR, Hadi AH

Toxicon, 1990;28(10):1237-9.

PMID: 2264070

Crude glycoside extracts from the plant, Sarcolobus globosus, were tested on the rat phrenic nerve-diaphragm, chick biventer cervicis and frog rectus abdominis preparations. Nerve-stimulated twitches were inhibited by the extract. The muscle paralysis was not similar to that by curare-like blockers as it was not reversed by neostigmine or by a tetanus. Although contractures to acetylcholine or carbachol were not affected by 0.6 mg/ml of the extract, higher concentration of the extracts (3 mg/ml) depressed the log dose-response curve of acetylcholine and carbachol. The results suggest that the neuromuscular blocking effect of the extracts is either dose-dependent or due to a mixture of toxins with presynaptic or postsynaptic actions.

The modern implementation of patient blood management (PBM) in Malaysia: the use of intravenous iron in severe anaemia with iron deficiency - A Case Report

Krishnamoorthy A, Hadi FA, Naidu A, Sathar J

Med J Malaysia, 2017 02;72(1):53-54.

PMID: 28255141

Anaemia is a common condition in Malaysia, and is mostly due to iron deficiency. In many cases, allogeneic blood transfusion (ABT) is administered unnecessarily to treat anaemia. Patient blood management (PBM) is a concept whereby a patient becomes his or her "own blood bank", instead of receiving ABT. The concept encompasses three pillars namely optimising erythropoiesis, minimising blood loss and harnessing human physiological reserve. We present a safe and fruitful outcome of managing severe anaemia without utilising any ABT, made possible with the PBM approach including administration of intravenous iron.

Fulltext Beyond the pale: Insights into hypopigmented mycosis fungoides - A case report

Nur Zafirah Z, Abdul Hadi A

Malays Fam Physician, 2024;19:47.

PMID: 39220235 DOI: 10.51866/cr.644

Hypopigmented mycosis fungoides (MF) is a rare variant of cutaneous T-cell lymphoma, a type of extranodal non-Hodgkin lymphoma. This report presents the case of a 9-year-old boy with a 2-year history of asymptomatic, hypopigmented skin lesions that were resistant to topical treatment. He was initially treated for a fungal skin infection and had received multiple courses of topical antifungals and steroids but showed no improvement, which led to further evaluation and a referral to a dermatologist. A skin biopsy was performed, and the diagnosis of hypopigmented MF was confirmed through skin histopathology and immunohistochemistry study. His lesions responded well to cycles of narrowband ultraviolet B phototherapy, showing almost complete clearance after 4 months without any side effects.

Fulltext Streptokinase after Spinal Anaesthesia – A Case Report

Hadi, M.R.A., Basri, M.N., Ariff, O.

International Medical Journal Malaysia, 2006;5(1):1-4.

MyJurnal

The use of thrombolytic agent e.g. streptokinase is indicated in patients with early acute ST elevation myocardial infarction (MI) (if there are no contraindications) is becoming increasingly routine. Its use is however significantly limited by bleeding complications. Spinal epidural haematoma (SEH) is haemorrhage in the spinal epidural space after spinal anaesthesia. SEH may be acute or chronic, spontaneous, posttraumatic, or iatrogenic but its occurrence appears to be particularly associated with acquired coagulopathy from medications and disease states. Patients usually present with acute axial spine pain and evolving focal neurological deficits. With increasing number of available anticoagulants and patient receiving them, anaesthesiologists today have to face the challenge of balancing between risks and benefits of regional anesthesia in patients under such medications. The treatment of this condition involves the principles of conservative follow-up directed by an improving examination and an understanding of the pathophysiology of coagulopathy-induced spontaneous epidural bleeds. When the diagnosis is accomplished rapidly, surgical decompression can result in full functional recovery.

Fulltext Classification of phishing websites using machine learning techniques

Hadi Zamani, Muhamad Kamal Mohammed Amin

Journal of Advanced Research in Applied Sciences and Engineering Technology, 2016;5(2):12-19.

MyJurnal

Phishing detection is a momentous problem which can be deliberated by many
researchers with numerous advanced approaches. Current anti-phishing mechanisms
such as blacklist-base anti-phishing, Heuristic-based anti-phishing does suffer low
detection accuracy and high false alarm. There is need for efficient mechanism to
protect users from phishing websites. The purpose of this study is to investigate the
capability of 6 machine learning algorithms i.e. Multi-Layer Perceptron (MLP), Support
Vector Machine (SVM), Random Forest (RF), Decision Tree (DT), Logistic Regression
(LR) and Naïve Bayes (NB) to classify phishing and non-phishing websites. These
algorithms were trained with two different groups of training in WEKA environment
and then were tested in terms of accuracy, precision, TP rate, and FP rate on a 3
different sets of dataset which contains dissimilar portion of phishing and non-phishing
instances. Results presented that Naïve Bayes classifier has better detection accuracy
between other classifiers for predicting phishing websites while Multi-Layer
Perceptron gave worst result in terms of detection accuracy. The result also showed
that Support Vector machine has better FP rate between other classifier. In addition,
Random Forest, Decision Tree, and Naïve Bayes can classify all phishing websites as
phishing correctly. It means that TP rate is 100% for these classifiers. In conclusion this
paper suggests using NB as the best classifier for predicting phishing and non-phishing
websites.

Fulltext Iatrogenic submandibular duct rupture complicating sialography: a case report

Sharouny H, Omar RB

Iran Red Crescent Med J, 2014 Sep;16(9):e7882.

PMID: 25593739 DOI: 10.5812/ircmj.7882

INTRODUCTION: Sialolithiasis is the most common disease of salivary glands. Sialography is particularly important for the assessment of the outflow tract and in diagnosing obstructive salivary gland lesions including calculi.

CASE PRESENTATION: We report on a 38-year-old female with sialolithiasis whom had Wharton's duct perforation, complicating the sialography. She was treated conservatively with a course of co-amoxiclav, oral prednisolone for three days and pain-killers. The patient was clinically well on follow-up reassessments at the end of the first week and three weeks post procedure.

CONCLUSIONS: Perforation of salivary duct complicating the sialography is rare. Awareness of this potential complication and utilizing a good sialography technique need to be advocated amongst radiologists. Response to treatment by conservative management is preferred as illustrated in this case.

Fulltext Endoscopic marsupialisation of the lateral frontal sinus mucocele with orbital extension: a case report

Sharouny H, Narayanan P

Iran Red Crescent Med J, 2015 Jan;17(1):e17104.

PMID: 25763256 DOI: 10.5812/ircmj.17104

INTRODUCTION: Frontal sinus mucoceles are the commonest among all paranasal mucoceles. With introduction of functional endoscopic sinus surgery, surgeons prefer endoscopic management of sinus mucoceles, but lesions that appear in the lateral part of the frontal sinus can be difficult to access and often need external approaches.

CASE PRESENTATION: We described a lateral frontal sinus mucocele with intra-orbital extension, which was successfully managed by endoscopic sinus surgery.

CONCLUSIONS: Endoscopic sinus surgery is the treatment of choice in most frontal sinus mucoceles including lateral frontal mucoceles.

Fulltext Iatrogenic aspiration of custom-made keel: a case report

Sharouny H, Omar RB

Iran Red Crescent Med J, 2014 Dec;16(12):e17066.

PMID: 25763237 DOI: 10.5812/ircmj.17066

INTRODUCTION: Laryngeal stenosis has various causes and treatment options. Endoscopic resection of the stenotic part with CO2 laser is one of the treatment options of laryngotracheal stenosis. Keels are useful for preventing adhesion formation, restenosis and web formation, which may happen during the later stage. They can be put in place either via the endoscopic approach or through a micro thyroidotomy and are held in place with a heavy suture through cricothyroid and thyrohyoid membranes. They are left in place for two to four weeks, and then removed through the endoscopic approach under general anesthetics.

CASE PRESENTATION: We report on a case of anterior glottis stenosis with keel aspiration for two weeks, after endoscopic CO2 laser resection of the stenotic section and keel placement. The patient was admitted to our center, where bronchoscopy was performed and the keel was removed. A new custom-made silastic keel was properly placed in raw areas and fixed to the skin with suture through the cricothyroid and thyrohyoid membranes. The keel was removed three weeks later.

CONCLUSIONS: Endoscopic keel placement should be done with heavy suture through cricothyroid and thyrohyoid membranes. Surgeons should suture the keel to the anterior laryngeal wall with specially designed Lichtenberger's needle-carriers to prevent complications such as keel aspiration, adhesion formation and imposing a second trip under general anesthetics, which put the patient at increased risk. The false vocal cord microflaps, as biological keels and a relatively new method may replace silastic keel placement in the future.

Fulltext Maxillary Sinus Mucopyocele in a Fifty-eight-year-old man: A Possible Late Complication of Irradiation to Head and Neck

Sharouny H, Narayanan P

Iran Red Crescent Med J, 2014 Jul;16(7):e17133.

PMID: 25237579 DOI: 10.5812/ircmj.17133

INTRODUCTION: A mucocele is an epithelial-lined, mucus-containing sac that can fill the sinus completely and expand gradually. Mucopyocele is an infected mucocele.

CASE REPORT: We presented a case of left maxillary mucopyocele in a 58-year-old man that developed after radiotherapy for nasopharyngeal carcinoma. Computed tomography scan showed opacification of the left maxillary sinus expanding through the medial wall of the antrum with thinning and destruction of the adjacent structures. Endoscopic marsupialization of the lesion and left partial maxillectomy were performed. The cystic mass had yellowish thick mucopurulent fluid that was completely drained.

CONCLUSIONS: A few cases of sphenoid sinus mucocele as a late complication of radiation therapy have been reported. Maxillary mucocele and mucopyocele can be considered as one of the late complications of radiotherapy to head and neck as a result of occlusion of sinus ostia by scarred mucosa.

Effect of MgO nanofillers on burst release reduction from hydrogel nanocomposites

Hezaveh H, Muhamad II

J Mater Sci Mater Med, 2013 Jun;24(6):1443-53.

PMID: 23515904 DOI: 10.1007/s10856-013-4914-5

In this study, MgO nanoparticles are applied to control the initial burst release by modification of matrix structure, thereby affecting the release mechanism. The effects of MgO nanofiller loading on the in vitro release of a model drug are investigated. Surface topography and release kinetics of hydrogel nanocomposites are also studied in order to have better insight into the release mechanism. It was found that the incorporation of MgO nanofillers can significantly decrease the initial burst release. The effect of genipin (GN) on burst release was also compared with MgO nanoparticles, and it was found that the impact of MgO on burst release reduction is more obvious than GN; however, GN cross-linking caused greater final release compared to blanks and nanocomposites. To confirm the capability of nanocomposite hydrogels to reduce burst release, the release of β-carotene in Simulated Gastric Fluid and Simulated Intestinal Fluid was also carried out. Thus, the application of MgO nanoparticles seems to be a promising strategy to control burst release.

The effect of nanoparticles on gastrointestinal release from modified κ-carrageenan nanocomposite hydrogels

Hezaveh H, Muhamad II

Carbohydr Polym, 2012 Jun 5;89(1):138-45.

PMID: 24750615 DOI: 10.1016/j.carbpol.2012.02.062

In this article, silver and magnetite nanofillers were synthesized in modified κ-carrageenan hydrogels using the in situ method. The effect of metallic nanoparticles in gastro-intestinal tract (GIT) release of a model drug (methylene blue) has been investigated. The effect of nanoparticles loading and genipin cross-linking on GIT release of nanocomposite is also studied to finally provide the most suitable drug carrier system. In vitro release studies revealed that using metallic nanocomposites hydrogels in GIT studies can improve the drug release in intestine and minimize it in the stomach. It was found that cross-linking and nanofiller loading can significantly improve the targeted release. Therefore, applying metallic nanoparticles seems to be a promising strategy to develop GIT controlled drug delivery.

Impact of metal oxide nanoparticles on oral release properties of pH-sensitive hydrogel nanocomposites

Hezaveh H, Muhamad II

Int J Biol Macromol, 2012 Jun 1;50(5):1334-40.

PMID: 22484730 DOI: 10.1016/j.ijbiomac.2012.03.017

In this article, modified κ-carrageenan hydrogel nanocomposites were synthesized to increase the release ability of carrageenan hydrogels under gastrointestinal conditions. The effect of MgO nanoparticle loading in a model drug (methylene blue) release is investigated. Characterization of hydrogels were carried out using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Field Emission Scanning Electron Microscope (FESEM) and Differential Scanning Calorimetry (DSC). Genipin was used to increase the delivery performance in gastrointestinal tract delivery by decreasing release in simulated stomach conditions and increasing release in simulated intestine conditions. It is shown that the amount of methylene blue released from genipin-cross-linked nanocomposites can be 67.5% higher in intestine medium and 56% lower in the stomach compared to κ-carrageenan hydrogel. It was found that by changing the nanoparticle loading and genipin concentration in the composite, the amount of drug released can be monitored. Therefore, applying nanoparticles appears to be a potential strategy to develop controlled drug delivery especially in gastrointestinal tract studies.

Fulltext Foreign bodies in the laryngotracheobronchial tree

Razi Hadi A, Said H, Ahmad K

Med J Malaysia, 1988 Mar;43(1):74-83.

PMID: 3244325

Foreign bodies in the laryngotracheobronchial tree are not uncommon. Their clinical presentations, the radiological and endoscopic findings in sixteen cases that presented to the Department of Otorhinolaryngology, Universiti Kebangsaan Malaysia were reviewed. The technique of removal is also discussed.
Study site: Hospital Kuala Lumpur, Malaysia (UKM unit)

A child with unique skin pattern: A case report of Tinea imbricata

Roslan SR, Abdul Hadi A

Med J Malaysia, 2022 Jan;77(1):113-115.

PMID: 35087009

This paper reports a case of Tinea imbricata in a young Orang Asli boy which was noted during his admission for severe symptomatic anemia. Upon discharge, he was started on syrup Griseofulvin 10mg/kg daily and Whitfield cream for 4 weeks. The Department of Orang Asli Development (JAKOA) and the local Health Clinic were contacted before discharge to facilitate patient's follow-up and monitoring. Outbreaks of Tinea imbricata among the Orang Asli have been known to happen from time to time. Although this dermatophyte infection is rare in the urban population, transmission among travelers has been reported. This case report highlights its unique presentation and treatment approach.

Displaying publications 1 - 20 of 638 in total