Displaying publications 1 - 20 of 993 in total

  1. Syed-Yahya SNN, Idris MA, Noblet AJ
    J Safety Res, 2022 Dec;83:105-118.
    PMID: 36481002 DOI: 10.1016/j.jsr.2022.08.008
    INTRODUCTION: Since its inception more than four decades ago, research on safety climate has been conducted in many industries. Subsequently, a plethora of systematic literature reviews on safety climate in various work environments has focused on research trends and measurement scales. Yet, despite these reviews, the overall picture of how safety climate influences performance is still not well understood. The current study reviews existing literature on safety climate, specifically how it affects safety performance.

    METHOD: Literature searches were conducted using EBSCOhost and Web of Science databases in March 2021. We included English-language, peer-reviewed studies that reported the results of research done on safety climate and safety performance. We extracted data (contextual, theoretical, methodological and definition of safety performance) from these studies and were deductively analyzed and categorized into common themes.

    RESULTS: One hundred and sixty-two safety climate studies were identified. We found that studies on safety climate-performance were conducted in 16 types of industries while 23 different theories explained the safety climate-performance relationship. The quantity and quality of variables and methods used varied considerably across the surveys. Safety climate is predominantly used as a predictor while safety-related behavior is the most common definition of safety performance among the articles we reviewed. Few papers from the current review were methodologically strong, suggesting that current evidence on the link between safety climate and safety performance still suffers from common method bias.

    CONCLUSIONS: Although literature has provided evidence for the positive effect on safety performance via a strong safety climate, strong and convincing methods are still lacking and the causality of an improved safety climate still needs to be demonstrated.

    PRACTICAL APPLICATIONS: The findings of the current review offer a better understanding of how employers can improve safety climate in the workplace in various settings.

    Matched MeSH terms: Organizational Culture*
  2. Abraham JJ
    Br Med J, 1912;1:438-446.
    Matched MeSH terms: Culture
  3. Teng CL, Kamil MA, Abu Hassan Z
    Family Physician, 2005;13:2-4.
    Matched MeSH terms: Culture
  4. Huang S, Huat KT, Liu Y
    Math Biosci Eng, 2023 Jun 29;20(8):14281-14305.
    PMID: 37679136 DOI: 10.3934/mbe.2023639
    In accordance with the theory of informal institutions, culture exerts a crucial influence on the enactment of corporate social responsibility. Based on the two core variables of Chinese traditional culture and corporate environmental responsibility, we designed a panel data model to investigate the impact of Chinese traditional culture on corporate environmental responsibility and its heterogeneity. The findings indicate the following: 1) Chinese traditional culture can promote the performance of corporate environmental responsibility. 2) Chinese traditional culture has a heterogeneous influence on the environmental responsibility of enterprises that depends on the ownership difference of enterprises; that is, the influence of traditional culture on the environmental responsibility of state-owned enterprises is stronger than that of non-state-owned enterprises. 3) Chinese traditional culture has a heterogeneous influence on the environmental responsibility of enterprises according to the difference in industrial pollution levels; that is, traditional culture has a positive correlation with the environmental responsibility of enterprises in heavily polluting industries and a negative correlation with non-heavily polluting industries. 4) Chinese traditional culture has a heterogeneous influence on corporate environmental responsibility according to geographical differences; that is to say, traditional culture promotes the development of corporate environmental responsibility in the central and western regions, and vice versa in the eastern regions.
    Matched MeSH terms: Culture*; Organizational Culture*
  5. Ma YC, Gao MR, Yang H, Jiang JY, Xie W, Su WP, et al.
    Appl Biochem Biotechnol, 2023 Jun;195(6):3628-3640.
    PMID: 36648604 DOI: 10.1007/s12010-023-04319-x
    C50 carotenoids, as unique bioactive molecules, have many biological properties, including antioxidant, anticancer, and antibacterial activity, and have a wide range of potential uses in the food, cosmetic, and biomedical industries. The majority of C50 carotenoids are produced by the sterile fermentation of halophilic archaea. This study aims to look at more cost-effective and manageable ways of producing C50 carotenoids. The basic medium, carbon source supplementation, and optimal culture conditions for Halorubrum sp. HRM-150 C50 carotenoids production by open fermentation were examined in this work. The results indicated that Halorubrum sp. HRM-150 grown in natural brine medium grew faster than artificial brine medium. The addition of glucose, sucrose, and lactose (10 g/L) enhanced both biomass and carotenoids productivity, with the highest level reaching 4.53 ± 0.32 μg/mL when glucose was added. According to the findings of orthogonal studies based on the OD600 and carotenoids productivity, the best conditions for open fermentation were salinity 20-25%, rotation speed 150-200 rpm, and pH 7.0-8.2. The up-scaled open fermentation was carried out in a 7 L medium under optimum culture conditions. At 96 h, the OD600 and carotenoids productivity were 9.86 ± 0.51 (dry weight 10.40 ± 1.27 g/L) and 7.31 ± 0.65 μg/mL (701.40 ± 21.51 μg/g dry weight, respectively). When amplified with both universal bacterial primer and archaeal primer in the open fermentation, Halorubrum remained the dominating species, indicating that contamination was kept within an acceptable level. To summarize, open fermentation of Halorubrum is a promising method for producing C50 carotenoids.
    Matched MeSH terms: Culture Media/chemistry
  6. Chua KB, Chua IL, Chua IE, Chong KH, Chua KH
    Malays J Pathol, 2005 Dec;27(2):99-105.
    PMID: 17191392
    A mycological medium was developed for primary isolation and culture of lipophilic yeasts. It was initially based on published information of nutrients and trace components that would promote the growth of these yeasts. It was subsequently modified and adjusted to specifically promote the growth of lipophilic yeasts and simultaneously avoid the luxurious growth of other fungi and bacteria. With this medium, the conventional bacteriological procedures such as microbial streaking for pure culture and anti-microbial sensitivity testing could be carried out for these lipophilic yeasts.
    Matched MeSH terms: Culture Media/chemistry*; Cell Culture Techniques/methods*
  7. Teng CL
    Family Physician, 1996;9(3):23-24.
    This article chronicles the popular health beliefs of the Malays and Chinese regarding chickenpox, as seen through the eyes of a doctor. The interplay of several factors, namely, a marriage of two major cultures, chickenpox in pregnancy, concurrence of two major festivals make this a unique study in medical socio-anthropology.
    Matched MeSH terms: Culture
  8. Khalib AL, Ngan HU
    Workplace bullying has drawn greater attention in the last one and half decades. Despite its recognition by many organizations and countries, it is still rife. Why is that so? Could it be that the root of the problem has not been addressed? Or, could it be due to difficulties and resistances in embarking preventive and control measures. In this paper, we will examine the possible causes of workplace bullying based on a proposed model. In depth discussion of the personal and organizational factors are made while the work group and societal factors are dealt with in brief. In summary, the root of workplace bullying is multi-factorial. Understanding the complexity and subtlety of workplace bullying is pertinent in the effort to prevent or curtail it.
    Matched MeSH terms: Organizational Culture
  9. Parker DB, Barrett RJ
    Intern Med J, 2003 Sep-Oct;33(9-10):463-4.
    PMID: 14511200 DOI: 10.1046/j.1445-5994.2003.00460.x
    Changes in medical research ethics in the past two decades have made the communication of risk to potential participants a legal imperative. Using ethnographic data from two different cultures, we examine the hazards associated with medical research in relation to the respective societal contexts that imbue them with meaning. The Iban, a Dayak people indigenous to Borneo, perceive the hazards of participating in research in terms of danger to the collective. In Australia they are construed in terms of risk to individuals. Risk in medical research is one manifestation of a broader notion of 'risk' that is constitutive of the research enterprise itself and, we argue, fundamental to post-industrial society.
    Matched MeSH terms: Culture*
  10. Saedi AM, Majid AA, Isa Z
    Int J Occup Saf Ergon, 2021 Sep;27(3):714-727.
    PMID: 31131712 DOI: 10.1080/10803548.2019.1623454
    Introduction. Demographic information is one of the key parameters that organizations utilize to modify their practices in order to respond to the existing risk within work environments. The present article aims to assess the level of safety climate factors as well as to evaluate the influence of personal factors on safety climate in two different-sized industries. Methods. A total of 216 employees in two large and three small and medium-sized chemical manufacturing industries responded to a questionnaire. Descriptive statistics were used to measure the safety climate level; a two-independent-sample Mann-Whitney U test and a Kruskal-Wallis test were run to compare the difference in safety climate scores among different demographic variables. Results. The lower level of safety climate in small and medium-sized industries revealed lower understanding and performance of management and non-management with regard to safety climate compared to the large industries. Additionally, significant mean differences on some safety climate factors among demographic variables were detected in both sizes of industries, emphasizing the important role of the employees' demographic variables on the plants' safety climate. Conclusion. Improving organization-level and group-level safety climates is recommended to improve employees' level of safety climate and control their personal factors.
    Matched MeSH terms: Organizational Culture*
  11. Lee, Pay Chiann, Kumar, Sures, Nor Aini Shukor
    This review paper discussed about publications related to micropropagation of bamboo species. In recent years, the application of tissue culture technique like in vitro micropropagation has been used to meet the demands for bamboo planting materials. In the past 30 years, protocols for micropropagation of various bamboo species have been established by researchers from all over the world. The controlling factors for cultures such as the explants, culture medium, carbon sources, combination and concentration of plant growth regulators and other additional additives are varied. The controlling factors are crucial in developing successful regeneration protocols for various bamboo species. This paper attempts to review and summarize the available and up-to-date information regarding in vitro micropropagation of bamboos.
    Matched MeSH terms: Culture Media; Tissue Culture Techniques
  12. Mohamed Sultan FM, Karuppannan G, Nyoto, Lestari H
    PLoS One, 2023;18(5):e0282941.
    PMID: 37192183 DOI: 10.1371/journal.pone.0282941
    School administration must pay attention to professional teachers' roles rather than nonprofessional teachers as part of important human resources in imparting learning. This study aims to analyse the influence of leadership, work environment, and organisational culture on the teachers' competence and performance in Prajnamitra Maitreya Foundation Pekanbaru, Indonesia. A total of 57 teachers participated in this research. A descriptive analysis of questionnaires and hypothesis analysis using path analysis was used to analyse the data from the saturated sampling method, where 57 teachers became the sample and were categorised based on age, gender, level of education, years of service, and work unit. Using Smart PLS (Partial Least Squares), this research revealed that leadership and work environment positively but non-significant affect the teachers' competence. Meanwhile, organisational culture has a positive and significant effect on the teachers' competence but a non-significant positive effect on the teachers' performance. Thus, the work environment and teacher's competence have a positive and significant effect on the teacher's performance, yet leadership has a negative and non-significant effect on the teacher's performance.
    Matched MeSH terms: Organizational Culture*
  13. Elsayed EA, Farid MA, El-Enshasy HA
    BMC Biotechnol, 2019 07 16;19(1):46.
    PMID: 31311527 DOI: 10.1186/s12896-019-0546-2
    BACKGROUND: Natamycin is an antifungal polyene macrolide antibiotic with wide applications in health and food industries. Currently, it is the only antifungal food additive with the GRAS status (Generally Regarded as Safe).

    RESULTS: Natamycin production was investigated under the effect of different initial glucose concentrations. Maximal antibiotic production (1.58 ± 0.032 g/L) was achieved at 20 g/L glucose. Under glucose limitation, natamycin production was retarded and the produced antibiotic was degraded. Higher glucose concentrations resulted in carbon catabolite repression. Secondly, intermittent feeding of glucose improved natamycin production due to overcoming glucose catabolite regulation, and moreover it was superior to glucose-beef mixture feeding, which overcomes catabolite regulation, but increased cell growth on the expense of natamycin production. Finally, the process was optimized in 7.5 L stirred tank bioreactor under batch and fed-batch conditions. Continuous glucose feeding for 30 h increased volumetric natamycin production by about 1.6- and 1.72-folds in than the batch cultivation in bioreactor and shake-flasks, respectively.

    CONCLUSIONS: Glucose is a crucial substrate that significantly affects the production of natamycin, and its slow feeding is recommended to alleviate the effects of carbon catabolite regulation as well as to prevent product degradation under carbon source limitation. Cultivation in bioreactor under glucose feeding increased maximal volumetric enzyme production by about 72% from the initial starting conditions.

    Matched MeSH terms: Culture Media/metabolism; Culture Media/chemistry; Batch Cell Culture Techniques/methods*
  14. Alfaqeh H, Chua KH, Aminuddin BS, Ruszymah BH
    Med J Malaysia, 2008 Jul;63 Suppl A:119-20.
    PMID: 19025014
    This study aimed to compare the effects of three different media on the in vivo chondrogenesis of sheep bone marrow stem cells (BMSC). Sheep BMSC were cultured in F12:DMEM + 10% FBS, chondrogenic medium containing 5ng/ml TGF,3 + 50ng/ml IGF-1 and UKM-MECC for three weeks. The cultured cells were then harvested for construct formation with fibrin. Constructed tissues were implanted subcutaneously into nude mice for in vivo development. Cell aggregates were formed in both chondrogenic medium and UKM-MECC demonstrated the early chondrogenesis process. After five weeks of in vivo development, both chondrogenic medium and UKM-MECC promoted cartilage matrix synthesis confirmed by Safranin O staining.
    Matched MeSH terms: Culture Media*; Cell Culture Techniques
  15. Abdul Manas NH, Chong LY, Tesfamariam YM, Zulkharnain A, Mahmud H, Abang Mahmod DS, et al.
    J Biotechnol, 2020 Jun 20;317:16-26.
    PMID: 32348830 DOI: 10.1016/j.jbiotec.2020.04.011
    Bacterial pigments are potential substitute of chemical photosensitizer for dye-sensitized solar cell (DSSC) due to its non-toxic property and cost-effective production from microbial fermentation. Serratia nematodiphila YO1 was isolated from waterfall in Malaysia and identified using 16S ribosomal RNA. Characterization of the red pigment produced by the bacteria has confirmed the pigment as prodigiosin. Prodigiosin was produced from the fermentation of the bacteria in the presence of different oil substrates. Palm oil exhibited the best performance of cell growth and equivalent prodigiosin yield compared to olive oil and peanut oil. Prodigiosin produced with palm oil supplementation was 93 mg/l compared to 7.8 mg/l produced without supplementation, which recorded 11.9 times improvement. Specific growth rate of the cells improved 1.4 times when palm oil was supplemented in the medium. The prodigiosin pigment produced showed comparable performance as a DSSC sensitizer by displaying an open circuit voltage of 336.1 mV and a maximum short circuit current of 0.098 mV/cm2. This study stands a novelty in proving that the production of prodigiosin is favorable in the presence of palm oil substrate with high saturated fat content, which has not been studied before. This is also among the first bacterial prodigiosin tested as photosensitizer for DSSC application.
    Matched MeSH terms: Culture Media/pharmacology; Culture Media/chemistry
  16. Saadatnia G, Haj Ghani H, Khoo BY, Maimunah A, Rahmah N
    Trop Biomed, 2010 Apr;27(1):125-30.
    PMID: 20562822
    In vitro culture of Toxoplasma gondii can provide tachyzoites which are active, viable and with desirable purity. Thus the aim of this study was to optimize the cell culture method for T. gondii propagation to obtain a consistent source of parasites with maximum yield and viability, but minimum host cell contamination for use in production of excretory-secretory antigen. Tachyzoites with seed counts of 1x10(6), 1x10(7) and 1x10(8) harvested from infected mice were added to VERO cells of different degrees of confluence, namely 50%, 85% and 100%, and examined periodically using an inverted microscope. When the maximum release of the tachyzoites was observed from the host cells, the culture supernatant was removed and the tachyzoites harvested. Using a Neubauer chamber, the percentages of viable tachyzoites and host cell contamination were determined using trypan blue stain. Parameters that gave the best yield and purity of viable tachyzoites were found to be as follows: VERO cells at 85% confluence in DMEM medium and inoculum comprising 1x10(7) tachyzoites. After about 3 days post infection, the tachyzoites multiplied 78x, with a yield of ~7.8x10(8) per flask, 99% viability and 3% host cell contamination. This study has successfully optimized the method of propagation of T. gondii tachyzoites in VERO cells which produce parasites with high yield, purity and viability.
    Matched MeSH terms: Culture Media; Cell Culture Techniques/methods*
  17. Koh B, Sulaiman N, Fauzi MB, Law JX, Ng MH, Yuan TL, et al.
    Int J Mol Sci, 2023 Feb 13;24(4).
    PMID: 36835154 DOI: 10.3390/ijms24043745
    Xeno-free three-dimensional cultures are gaining attention for mesenchymal stem cell (MSCs) expansion in clinical applications. We investigated the potential of xeno-free serum alternatives, human serum and human platelet lysate, to replace the current conventional use of foetal bovine serum for subsequent MSCs microcarrier cultures. In this study, Wharton's Jelly MSCs were cultured in nine different media combinations to identify the best xeno-free culture media for MSCs culture. Cell proliferation and viability were identified, and the cultured MSCs were characterised in accordance with the minimal criteria for defining multipotent mesenchymal stromal cells by the International Society for Cellular Therapy (ISCT). The selected culture media was then used in the microcarrier culture of MSCs to determine the potential of a three-dimensional culture system in the expansion of MSCs for future clinical applications, and to identify the immunomodulatory potential of cultured MSCs. Low Glucose DMEM (LG) + Human Platelet (HPL) lysate media appeared to be good candidates for replacing conventional MSCs culture media in our monolayer culture system. MSCs cultured in LG-HPL achieved high cell yield, with characteristics that remained as described by ISCT, although the overall mitochondrial activity of the cells was lower than the control and the subsequent effects remained unknown. MSC microcarrier culture, on the other hand, showed comparable cell characteristics with monolayer culture, yet had stagnated cell proliferation, which is potentially due to the inactivation of FAK. Nonetheless, both the MSCs monolayer culture and the microcarrier culture showed high suppressive activity on TNF-α, and only the MSC microcarrier culture has a better suppression of IL-1 secretion. In conclusion, LG-HPL was identified as a good xeno-free media for WJMSCs culture, and although further mechanistic research is needed, the results show that the xeno-free three-dimensional culture maintained MSC characteristics and improved immunomodulatory activities, suggesting the potential of translating the monolayer culture into this culture system in MSC expansion for future clinical application.
    Matched MeSH terms: Culture Media; Cell Culture Techniques/methods
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